• Animal Bioscience
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• v.37 no.6
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• pp.1096-1109
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• 2024

Objective: This research aims to explore the nutritional and bioactive peptide properties of goat meat taken from various primal cuts, including the breast, shoulder, rib, loin, and leg, to produce these bioactive peptides during in vitro gastrointestinal (GI) digestion and absorption. Methods: The goat meat from various primal cuts was obtained from Boer goats with an average carcass weight of 30±2 kg. The meat was collected within 3 h after slaughter and was stored at -80℃ until analysis. A comprehensive assessment encompassed various aspects, including the chemical composition, cooking properties, in vitro GI digestion, bioactive characteristics, and the bioavailability of the resulting peptides. Results: The findings indicate that the loin muscles contain the highest protein and essential amino acid composition. When the meats were cooked at 70℃ for 30 min, they exhibited distinct protein compositions and quantities in the sodium dodecyl sulfate-polyacrylamide gel electrophoresis profile, suggesting they served as different protein substrates during GI digestion. Subsequent in vitro simulated GI digestion revealed that the cooked shoulder and loin underwent the most significant hydrolysis during the intestinal phase, resulting in the strongest angiotensin-converting enzyme (ACE) and dipeptidyl peptidase-IV (DPP-IV) inhibition. Following in vitro GI peptide absorption using a Caco-2 cell monolayer, the GI peptide derived from the cooked loin demonstrated greater bioavailability and a higher degree of ACE and DPP-IV inhibition than the shoulder peptide. Conclusion: This study highlights the potential of goat meat, particularly cooked loin, as a functional meat source for protein, essential amino acids, and bioactive peptides during GI digestion and absorption. These peptides promise to play a role in preventing and treating metabolic diseases due to their dual inhibitory effects on ACE and DPP-IV.

• Journal of the Korea institute for structural maintenance and inspection
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• v.28 no.2
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• pp.61-68
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• 2024

The majority of high-speed railway bridges along the domestic Gyeongbu and Honam lines feature a PSC-box type structure with a span length ranging from 35 to 40m, which typically exhibits a first bending natural frequency of approximately 4 to 5Hz. When KTX high-speed trains transverse these bridges at speeds ranging from 290 to 310km/h, the vibration induced by the trains approaches the first bending natural frequency of the bridge. Furthermore, with the upcoming operation of a EMU-320 high-speed train and the anticipated increase in the speeds of these high-speed trains, there is a need to analyze the dynamic response of high-speed railway bridges. For this, based on measured responses from actual railway bridges, a numerical model was constructed using a numerical model updating technique. The dynamic response of the updated numerical model exhibited a strong agreement with the measured response from the actual railway bridges. Subsequently, this updated model was utilized to analyze the dynamic response characteristics of the bridges when KTX and EMU-320 trains operate at increased speeds. The maximum vertical displacement and acceleration at the mid-span of the bridges were also compared to those specified in the railway design standard with the increasing speed of KTX and EMU-320.

• Korean Journal of Radiology
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• v.22 no.11
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• pp.1764-1776
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• 2021

Objective: This study aimed to validate a deep learning-based fully automatic calcium scoring (coronary artery calcium [CAC]_auto) system using previously published cardiac computed tomography (CT) cohort data with the manually segmented coronary calcium scoring (CAC_hand) system as the reference standard. Materials and Methods: We developed the CAC_auto system using 100 co-registered, non-enhanced and contrast-enhanced CT scans. For the validation of the CAC_auto system, three previously published CT cohorts (n = 2985) were chosen to represent different clinical scenarios (i.e., 2647 asymptomatic, 220 symptomatic, 118 valve disease) and four CT models. The performance of the CAC_auto system in detecting coronary calcium was determined. The reliability of the system in measuring the Agatston score as compared with CAC_hand was also evaluated per vessel and per patient using intraclass correlation coefficients (ICCs) and Bland-Altman analysis. The agreement between CAC_auto and CAC_hand based on the cardiovascular risk stratification categories (Agatston score: 0, 1-10, 11-100, 101-400, > 400) was evaluated. Results: In 2985 patients, 6218 coronary calcium lesions were identified using CAC_hand. The per-lesion sensitivity and false-positive rate of the CAC_auto system in detecting coronary calcium were 93.3% (5800 of 6218) and 0.11 false-positive lesions per patient, respectively. The CAC_auto system, in measuring the Agatston score, yielded ICCs of 0.99 for all the vessels (left main 0.91, left anterior descending 0.99, left circumflex 0.96, right coronary 0.99). The limits of agreement between CAC_auto and CAC_hand were 1.6 ± 52.2. The linearly weighted kappa value for the Agatston score categorization was 0.94. The main causes of false-positive results were image noise (29.1%, 97/333 lesions), aortic wall calcification (25.5%, 85/333 lesions), and pericardial calcification (24.3%, 81/333 lesions). Conclusion: The atlas-based CAC_auto empowered by deep learning provided accurate calcium score measurement as compared with manual method and risk category classification, which could potentially streamline CAC imaging workflows.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.44 no.1
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• pp.41-48
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• 2024

In 2017, the Ministry of the Interior and Safety conducted research for the revision of seismic design standards and performed studies on standard design response spectra. As a result, the Common Application Guidelines for Seismic Design Standards were introduced, and these guidelines have been implemented in the national design standards of the Ministry of Land, Infrastructure, and Transport for practical use. However, it should be noted that the research for proposing standard design response spectra during the 2017 revision was conducted before the occurrence of the significant seismic events in South Korea, such as the 2016 Gyeongju Earthquake and the 2017 Pohang Earthquake. To account for these recent major earthquakes, this study adjusted the standard design spectra based on the records of the 2016 Gyeongju Earthquake and the 2017 Pohang Earthquake and conducted ground response analyses accordingly. The results revealed variations in peak ground acceleration (PGA) at the ground surface even within the same ground classification. It was confirmed that this variation can lead to overestimation or underestimation of seismic loads.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.44 no.1
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• pp.49-62
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• 2024

Reckless development of the underground by rapid urbanization causes inspection delay on replacement of existing structure and installation new facilities. However, frequent accidents occur due to deviation in construction design planned by inaccurate location information of underground structure. Meanwhile, the electrical resistivity survey, knowns as non-destructive method, is based on the difference in the electric potential of electrodes to measure the electrical resistance of ground. This method is significantly advanced with multi-electrode and deep learning for analyzing strata. However, there is no study to quantitatively assess change in electrical resistance according to geometric conditions of structures. This study evaluates changes in electrical resistance through geometric parameters of electrodes and structure. Firstly, electrical resistance numerical module is developed using generalized mesh occurring minimal errors between theoretical and numerical resistance values. Then, changes in resistances are quantitatively compared on geometric parameters including burial depth, diameter of structure, and distance electrode and structure under steady current condition. The results show that higher electrical resistance is measured for shallow depth, larger size, and proximity to the electrode. Additionally, electric potential and current density distributions are analyzed to discuss the measured electrical resistance around the terminal electrode and structure.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.44 no.1
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• pp.95-100
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• 2024

The public survey performance review conducted by the Spatial Information Quality Management Institute is conducted at the screening rate in accordance with the regulations, and the examiner directly judges the overall trend of the submitted performance based on the extracted sample. However, the evaluation of the Ministry of Land, Infrastructure and Transport, the evaluation trustee shall be specified by random extraction (Random Collection) is specified by the sample. In this study, it analyzed the details of the actual site and analyzed through securing actual performance review data. In addition, we analyzed considerations according to various field conditions and studied ways to apply the public survey performance review sampling algorithm. Therefore, detailed sampling criteria analysis by performance reviewers is necessary. A relative comparison was made feasible by comparing the data for which the real performance evaluation was performed with the outcomes of the Python automation program. This automation program is expected to be employed as a foundation program for the automated application of public survey performance evaluation sampling in the future.

• Journal of the Korean Geotechnical Society
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• v.40 no.1
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• pp.47-54
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• 2024

In current slope stability analysis techniques, slope stability is evaluated based on the saturated-soil theory. However, soil-water characteristics change frequently depending on the climate. Therefore, because the saturated soil theory has limitations, the application of the unsaturated soil theory is necessary for slope stability. It is also important to evaluate the engineering properties of unsaturated soil because the capillary absorption capacity is reduced due to heavy rain, thereby causing a reduction in slope stability. In this study, soil-water characteristic tests were performed using four samples with different fine contents (0%, 10%, 20%, and 30%) using granite-weathered soil in domestic production areas. In particular, to consider the previously conducted drying process as well as the evaluation of stability due to heavy rain on the actual slope, a wetting process was conducted, in which the water content was increased. In addition, the van Genuchten (1980) model, which is the most consistent theoretical equation for the experiment, was used with various theoretical equations, and the parameters were analyzed according to the fine content of the granite-weathered soil for the drying and wetting processes.

• Journal of the korean academy of Pediatric Dentistry
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• v.51 no.2
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• pp.149-164
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• 2024

This study compared the solubility, water absorption, dimensional stability, release of various ions (hydroxyl, calcium, sulfur, strontium, and silicon), and cytotoxicity of light-cured resin-modified pulp-capping materials. Resin-modified calcium hydroxide (Ultra-blend^TM plus, UBP), light-cured resin-modified calcium silicate (TheraCal LC^TM, TLC), and dual-cure resin-modified calcium silicate (TheraCal PT^TM, TPT) were used. Each material was polymerized; solubility, 24-hour water absorption, and 30- day dimensional stability experiments were conducted to test its physical properties. Solubility was assessed according to the ISO 6876 standard, and 24 hours of water absorption, 30 days of dimensional stability were assessed by referring to the previous protocol respectively. Eluates at 3 and 24 hours and on 7, 14, and 28 days were analyzed according to the ISO 10993-12 standard. And the pH, Ion-releasing ability, cell proliferation rate, and cell viability were assessed using the eluates to evaluate biochemical characteristics. pH was measured with a pH meter and Ion-releasing ability was assessed using inductively coupled plasma atomic emission spectrometry (ICP-AES). Cell proliferation rate and cell viability were assessed using human dental pulp cells (hDPCs). The former was assessed by an absorbance assay using the CCK-8 solution, and the latter was assessed by Live and Dead staining. TPT exhibited lower solubility and water absorption than TLC. UBP and TPT demonstrated higher stability than TLC. The release of sulfur, strontium, calcium, and hydroxyl ions was higher for TLC and TPT than for UBP. The 28-day release of hydroxyl and silicon ions was similar for TLC and TPT. TLC alone exhibited a lower cell proliferation rate compared to the control group at a dilution ratio of 1 : 2 in cell proliferation and dead cells from Live and Dead assay evaluation. Thus, when using light-cure resin-modified pulp-capping materials, calcium silicate-based materials can be considered alternatives to calcium hydroxide-based materials. Moreover, when comparing physical and biochemical properties, TPT could be prioritized over TLC as the first choice.

• Korean Chemical Engineering Research
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• v.62 no.1
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• pp.27-35
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• 2024

Fuel gases such as methane and propane are used in explosion hazardous area of domestic plants and can form non-uniform mixtures with the influence of process conditions due to leakage. The fire-explosion risk assessment using literature data measured under uniform mixtures, damage prediction can be obtained the different results from actual explosion accidents by gas leaks. An explosion characteristics such as explosion pressure and flame velocity of non-uniform gas mixtures with concentration change similar to that of facility leak were examined. The experiments were conducted in a closed 0.82 m long stainless steel duct with observation recorded by color high speed camera and piezo pressure sensor. Also we proposed the quantification method of non-uniform mixtures from a regression analysis model on the change of concentration difference with time in explosion duct. For the non-uniform condition of this study, the area of flame surface enlarged with increasing the concentration non-uniform in the flame propagation of methane and was similar to the wrinkled flame structure existing in a turbulent flame. The time to peak pressure of methane decreased as the non-uniform increased and the explosion pressure increased with increasing the non-uniform. The ranges of K_G (Deflagration index) of methane with the concentration non-uniform were 1.30 to 1.58 [MPa·m/s] and the increase rate of K_G was 17.7% in methane with changing from uniform to non-uniform.

• Design & Manufacturing
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• v.17 no.4
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• pp.33-41
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• 2023

Excessive use of plastic bottles contributes to a significant environmental issue due to the high volume of plastic waste generated. To address this, efforts are needed to reduce the weight of plastic bottles. However, indiscriminate weight reduction may compromise the essential rigidity required for plastic bottles. Extensive research on rib shape for pressure vessels are exists, but there is a few research of rib shapes to enhance the stiffness of plastic bottles. The following results were obtained from the analyses conducted in this study. 1) Among the rib cross-sections of square, trapezoid, and triangle, the buckling critical load of PET bottles with square-shaped ribs is improved by about 14% compared to the buckling critical load of PET bottles without ribs. 2) The buckling critical load is improved by about 18% when a square-shaped rib with an aspect ratio of 0.2 is applied, compared to the buckling critical load of the bottle without the rib. 3) When longitudinal and transverse square ribs were applied to the axial direction of the PET bottle, the buckling critical load was improved by about 32% and 58% compared to the buckling critical load of the PET bottle without ribs, respectively, indicating that applying longitudinal ribs is effective in reinforcing the stiffness of PET bottles. 4) When 14 transverse ribs were applied, the maximum improvement was about 48% compared to the buckling critical load of the plastic bottle without ribs. 5) When 3 longitudinal ribs were applied on each side, the maximum improvement was about 76% compared to the buckling critical load of the bottle without ribs. Therefore, it was concluded that for effective stiffness reinforcement of a 500ml square bottle with a thickness of 0.5mm, 3 square-shaped ribs with an aspect ratio of 0.2 should be applied in the longitudinal direction relative to the axial direction of the bottle.