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A Study on Breakdown Patterns which influence Down-Time of Medical Equipment (의료기기의 Down-Time에 영향을 미치는 고장유형에 관한 연구)

  • Seo, G.H.;Han, K.D.;Kim, H.K.;Lee, H.S.;Lim, H.S.;Kwon, H.N.
    • Proceedings of the KOSOMBE Conference
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    • v.1998 no.11
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    • pp.100-101
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    • 1998
  • In this paper, we've studied on the Breakdownpatterns which hove an effect on Down-Time of Medical Equipment. This study is based on the statistics of MMS(Maintenance Management System) accumulated since the opening of Samsung Medical Center. We hope that this paper, which is acquired through the analysis about the seasonal feature, the work pattern feature and the period used, is useful to reduce a term of Down-Time and to retrench hospital management cost.

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Molecular Cloning and Characterization of the Yew Gene Encoding Squalene Synthase from Taxus cuspidata

  • Huang, Zhuoshi;Jiang, Keji;Pi, Yan;Hou, Rong;Liao, Zhihua;Cao, Ying;Han, Xu;Wang, Qian;Sun, Xiaofen;Tang, Kexuan
    • BMB Reports
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    • v.40 no.5
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    • pp.625-635
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    • 2007
  • The enzyme squalene synthase (EC 2.5.1.21) catalyzes a reductive dimerization of two farnesyl diphosphate (FPP) molecules into squalene, a key precursor for the sterol and triterpene biosynthesis. A full-length cDNA encoding squalene synthase (designated as TcSqS) was isolated from Taxus cuspidata, a kind of important medicinal plants producing potent anti-cancer drug, taxol. The full-length cDNA of TcSqS was 1765 bp and contained a 1230 bp open reading frame (ORF) encoding a polypeptide of 409 amino acids. Bioinformatic analysis revealed that the deduced TcSqS protein had high similarity with other plant squalene synthases and a predicted crystal structure similar to other class I isoprenoid biosynthetic enzymes. Southern blot analysis revealed that there was one copy of TcSqS gene in the genome of T. cuspidata. Semi-quantitative RT-PCR analysis and northern blotting analysis showed that TcSqS expressed constitutively in all tested tissues, with the highest expression in roots. The promoter region of TcSqS was also isolated by genomic walking and analysis showed that several cis-acting elements were present in the promoter region. The results of treatment experiments by different signaling components including methyl-jasmonate, salicylic acid and gibberellin revealed that the TcSqS expression level of treated cells had a prominent diversity to that of control, which was consistent with the prediction results of TcSqS promoter region in the PlantCARE database.

Collapse risk evaluation method on Bayesian network prediction model and engineering application

  • WANG, Jing;LI, Shucai;LI, Liping;SHI, Shaoshuai;XU, Zhenhao;LIN, Peng
    • Advances in Computational Design
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    • v.2 no.2
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    • pp.121-131
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    • 2017
  • Collapse was one of the typical common geological hazards during the construction of tunnels. The risk assessment of collapse was an effective way to ensure the safety of tunnels. We established a prediction model of collapse based on Bayesian Network. 76 large or medium collapses in China were analyzed. The variable set and range of the model were determined according to the statistics. A collapse prediction software was developed and its veracity was also evaluated. At last the software was used to predict tunnel collapses. It effectively evaded the disaster. Establishing the platform can be subsequent perfect. The platform can also be applied to the risk assessment of other tunnel engineering.

A new decision method for construction scheme of shallow buried subway station

  • Qiu, Daohong;Yu, Yuehao;Xue, Yiguo;Su, Maoxin;Zhou, Binghua;Gong, Huimin;Bai, Chenghao;Fu, Kang
    • Geomechanics and Engineering
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    • v.30 no.3
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    • pp.313-324
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    • 2022
  • With the development of the economy, people's utilization of underground space are also improved, and a large number of cities have begun to build subways to relieve traffic pressure. The choice of subway station construction method is crucial. If an inappropriate construction method is selected, it will not only waste costs but also cause excessive deformation that may also threaten construction safety. In this paper, a subway station construction scheme selects model based on the AHP-fuzzy comprehensive evaluation. The rationality of the model is verified using numerical simulation and monitoring measurement data. Firstly, considering the economy and safety, a comprehensive evaluation system is established by selecting several indicators. Then, the analytic hierarchy process is used to determine the weight of the evaluation index, and the dimensionless membership in the fuzzy comprehensive evaluation method is used to evaluate the advantages and disadvantages of the construction method. Finally, the method is applied to Liaoyang east road station of Qingdao metro Line 2, and the results are verified by numerical simulation and monitoring measurement data. The results show that the model is scientific, practical and applicable.