• Title/Summary/Keyword: Endocrine disruptor

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In vitro approach to investigating the free radical generation of endocrine disruptor

  • Kim HJ;Kim BH;An KH
    • Proceedings of the Korea Society of Environmental Toocicology Conference
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    • 2001.05a
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    • pp.117-117
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    • 2001
  • We investigated Free radical generation of endocrine disrupter, bisphenol A and alkyl esters of phthalic acid (DEP, DBP) using lipid peroxidation, enzyme assay (SOD, Catalase, Gpx-px), Cell viability and phototoxicity. Bisphenol A are monomers of various plastics including polycarbonates and epoxy resins which are used in numerous consumer products. The release of BPA from some of these materials has recently been reported. (omitted)

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The substitution of paper cup for the PSP noodle cup (컵라면 용기의 종이컵 대체)

  • Kim, Seong-Jin
    • KOREAN JOURNAL OF PACKAGING SCIENCE & TECHNOLOGY
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    • v.5 no.2
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    • pp.59-62
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    • 1999
  • After reported that Styrene dimer and Styrene trimer was Endocrine Disrupter, if it was a fact or not, the sales of PSP noodle cup was rapidly decreased and social responsibilities of the substitution materials development was raised. Therefore we had studied many materials like paper, pulp mold, PP injection molding, PP lamination, etc as substitution materials and selected paper cup which was safe in many sides and easy to recycle. Mainly we had checked the shape, safety, stability and recycling possibility of paper cup and secured many data which could prove them.

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A Study on the Cognition of High School Students and Science Teachers of Seoul and Province of Gyeonggi on the Endocrine Disruptors (서울 경기지역 고등학교의 학생가 과학 교사의 내분비계 장애 물질(환경 호르몬)에 대한 인식 조사)

  • Choi, Soo-Yeun;So, Keum-Hyun;Shim, Kew-Cheol;Yeau, Sung-Hee
    • Hwankyungkyoyuk
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    • v.19 no.3
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    • pp.93-101
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    • 2006
  • The purpose of this study was to investigate the cognition of high school students and science teachers on the endocrine disruptors. Subjects of this study were 204 high school students and 26 science teachers. The results were as follows. Students obtained informations about endocrine disruptors mainly through mass media like TV, radio or lesson in school. Most of them were interested in endocrine disruptors and they thought that endocrine disruptors were very dangerous for people. And they preferred learning materials such as movies, images, and animations, but they didn't want to participate in activity of education on endocrine disruptors actively. Science teachers has agreed to needs of education on endocrine disruptors and has required education programs such as movies, images or animations for effective endocrine disruptors education.

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Gene Expression Profiles of Dibutyl Phthalate and 17$\beta$-Estradiol using cDNA microarray in MCF 7 Human Breast Cancer Cell Line

  • Ryu, Jae-Chun;Kim, Hyung-Tae;Kim, Youn-Jung
    • Environmental Mutagens and Carcinogens
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    • v.22 no.4
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    • pp.274-278
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    • 2002
  • Phthalates, suspected endocrine disruptor, are plasticizer and solvent used in industry, and some phthalates are known as potential carcinogen. Most common human exposure to this compounds may occur with contaminated food. It may migrate into food from plastic wrap or may enter food from general environmental contamination, and it has become widespread environmental pollutants, thus leading to a variety of phthalates that possibly threaten the public health. Dibutyl phthalate (DBP) may playa part of cell proliferator, which mediates changes in gene expression and the metabolism of xenobiotics. An understanding of the role of DBP in modulating gene regulation should provide insight regarding mechanisms of DBP induced xenoestrogenic impact. To elucidate the type of genes that are associated with estrogenic activity induced by DBP at the dose (10$^{-8}$ M) appeared proliferating effects, the pattern of gene expression in MCF7 cells was compared between 17$\beta$-estradiol and DBP exposure in the cDNA microarray. From the results, it showed some differences of gene expression patterns between MCF7 cells treated with 17$\beta$-estradiol and DBP, and also DBP shows estrogenic potential with changes in estrogen-related gene expression levels.

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