• 한국전산유체공학회:학술대회논문집
• /
• 2009.11a
• /
• pp.151-158
• /
• 2009

To implement the insects' flapping flight for developing flapping MAVs(micro air vehicles), the unsteady flow characteristics of the insects' forward flight is investigated. In this paper, two-dimensional FSI(Fluid-Structure Interaction) simulations are conducted to examine realistic flow features of insects' flapping flight and to examine the flexibility effects of the insect's wing. The unsteady incompressible Navier-Stokes equations with an artificial compressibility method are implemented as the fluid module while the dynamic finite element equations using a direct integration method are employed as the solid module. In order to exchange physical information to each module, the common refinement method is employed as the data transfer method. Also, a simple and efficient dynamic grid deformation technique based on Delaunay graph mapping is used to deform computational grids. Compared to the earlier researches of two-dimensional rigid wing simulations, key physical phenomena and flow patterns such as vortex pairing and vortex staying can still be observed. For example, lift is mainly generated during downstroke motion by high effective angle of attack caused by translation and lagging motion. A large amount of thrust is generated abruptly at the end of upstroke motion. However, the quantitative aspect of flow field is somewhat different. A flexible wing generates more thrust but less lift than a rigid wing. This is because the net force acting on wing surface is split into two directions due to structural flexibility. As a consequence, thrust and propulsive efficiency was enhanced considerably compared to a rigid wing. From these numerical simulations, it is seen that the wing flexibility yields a significant impact on aerodynamic characteristics.

• Journal of Veterinary Science
• /
• v.23 no.2
• /
• pp.40.1-40.13
• /
• 2022

Background: Somatic cell nuclear transfer (SCNT) is used widely in cloning, stem cell research, and regenerative medicine. The type of donor cells is a key factor affecting the SCNT efficiency. Objectives: This study examined whether urine-derived somatic cells could be used as donors for SCNT in pigs. Methods: The viability of cells isolated from urine was assessed using trypan blue and propidium iodide staining. The H3K9me3/H3K27me3 level of the cells was analyzed by immunofluorescence. The in vitro developmental ability of SCNT embryos was evaluated by the blastocyst rate and the expression levels of the core pluripotency factor. Blastocyst cell apoptosis was examined using a terminal deoxynucleotidyl transferase dUTP nick end-labeling assay. The in vivo developmental ability of SCNT embryos was evaluated after embryo transfer. Results: Most sow urine-derived cells were viable and could be cultured and propagated easily. On the other hand, most of the somatic cells isolated from the boar urine exhibited poor cellular activity. The in vitro development efficiency between the embryos produced by SCNT using porcine embryonic fibroblasts (PEFs) and urine-derived cells were similar. Moreover, The H3K9me3 in SCNT embryos produced from sow urine-derived cells and PEFs at the four-cell stage showed similar intensity. The levels of Oct4, Nanog, and Sox2 expression in blastocysts were similar in the two groups. Furthermore, there is a similar apoptotic level of cloned embryos produced by the two types of cells. Finally, the full-term development ability of the cloned embryos was evaluated, and the cloned fetuses from the urine-derived cells showed absorption. Conclusions: Sow urine-derived cells could be used to produce SCNT embryos.

• Journal of the Korean Society for Aeronautical & Space Sciences
• /
• v.38 no.8
• /
• pp.747-757
• /
• 2010

The ice accreted on the airfoil is one of the critical drivers that causes the degradation of aerodynamic performance as well as aircraft accidents. Hence, an efficient numerical code to predict the accreted ice shape is crucial for the successful design of de-icing and anti-icing devices. To this end, a numerical code has been developed for the prediction of glaze ice accretion shape on 2D airfoil. Constant Source-Doublet method is used for the purpose of computational efficiency and heat transfer in the icing process is accounted for by Messinger model. The computational results are thoroughly compared against available experiments and other computation codes such as LEWICE and TRAJICE. The direction and thickness of ice horn are shown to yield similar results compared to the experiments and other codes. In addition, the effects of various parameters - temperature, free-stream velocity, liquid water contents, and droplet diameter - on the ice shape are systematically analyzed through parametric studies.

• Korean Journal of Plant Tissue Culture
• /
• v.27 no.6
• /
• pp.423-428
• /
• 2000

In 1997 when cloned sheep Dolly and soon after Polly were born, it had become head-line news because in the former the nucleus that gave rise to the lamb came from cells of six-year-old adult sheep and in the latter case a foreign gene was inserted into the donor nucleus to make the cloned sheep produce human protein, factor IX, in e milk. In the last few years, once the realm of science fiction, cloned mammals especially in livestock have become almost commonplace. What the press accounts often fail to convey, however, is that behind every success lie hundreds of failures. Many of the nuclear-transferred egg cells fail to undergo normal cell divisions. Even when an embryo does successfully implant in the womb, pregnancy often ends in miscarriage. A significant fraction of the animals that are born die shortly after birth and some of those that survived have serious developmental abnormalities. Efficiency remains at less than one % out of some hundred attempts to clone an animal. These facts show that something is fundamentally wrong and enormous hurdles must be overcome before cloning becomes practical. Cloning researchers now tent to put aside their effort to create live animals in order to probe the fundamental questions on cell biology including stem cells, the questions of whether the hereditary material in the nucleus of each cell remains intact throughout development, and how transferred nucleus is reprogrammed exactly like the zygotic nucleus. Stem cells are defined as those cells which can divide to produce a daughter cell like themselves (self-renewal) as well as a daughter cell that will give rise to specific differentiated cells (cell-differentiation). Multicellular organisms are formed from a single totipotent stem cell commonly called fertilized egg or zygote. As this cell and its progeny undergo cell divisions the potency of the stem cells in each tissue and organ become gradually restricted in the order of totipotent, pluripotent, and multipotent. The differentiation potential of multipotent stem cells in each tissue has been thought to be limited to cell lineages present in the organ from which they were derived. Recent studies, however, revealed that multipotent stem cells derived from adult tissues have much wider differentiation potential than was previously thought. These cells can differentiate into developmentally unrelated cell types, such as nerve stem cell into blood cells or muscle stem cell into brain cells. Neural stem cells isolated from the adult forebrain were recently shown to be capable of repopulating the hematopoietic system and produce blood cells in irradiated condition. In plants although the term$\boxDr$ stem cell$\boxUl$is not used, some cells in the second layer of tunica at the apical meristem of shoot, some nucellar cells surrounding the embryo sac, and initial cells of adventive buds are considered to be equivalent to the totipotent stem cells of mammals. The telomere ends of linear eukaryotic chromosomes cannot be replicated because the RNA primer at the end of a completed lagging strand cannot be replaced with DNA, causing 5' end gap. A chromosome would be shortened by the length of RNA primer with every cycle of DNA replication and cell division. Essential genes located near the ends of chromosomes would inevitably be deleted by end-shortening, thereby killing the descendants of the original cells. Telomeric DNA has an unusual sequence consisting of up to 1,000 or more tandem repeat of a simple sequence. For example, chromosome of mammal including human has the repeating telomeric sequence of TTAGGG and that of higher plant is TTTAGGG. This non-genic tandem repeat prevents the death of cell despite the continued shortening of chromosome length. In contrast with the somatic cells germ line cells have the mechanism to fill-up the 5' end gap of telomere, thus maintaining the original length of chromosome. Cem line cells exhibit active enzyme telomerase which functions to maintain the stable length of telomere. Some of the cloned animals are reported prematurely getting old. It has to be ascertained whether the multipotent stem cells in the tissues of adult mammals have the original telomeres or shortened telomeres.

• Animal Bioscience
• /
• v.35 no.3
• /
• pp.475-483
• /
• 2022

Objective: Methionine (Met) is involved in methyl group transfer besides protein synthesis. As the availability is limited and cost is high for synthetic Met, reductions in its inclusion in broiler diet may be possible by supplementing the low Met diets with methyl donors (MD) like betaine (Bet), folic acid (FA), vitamin B12 (B12), and biotin (Bio). An experiment was conducted to study the effects of supplementing the MD on performance (average daily gain [ADG], daily feed intake, feed efficiency [FE]), anti-oxidant variables, immune responses and serum protein concentration in broilers fed sub-optimal concentrations of dietary Met. Methods: Maize-soybean meal diet was used as control (CD). Different MD like Bet (0.2%), B12 (0.1 mg), FA (4 mg), or Bio (1.5 mg/kg) were supplemented to basal diet (BD) having no supplemental Met. The BD without MD was kept for comparison. Each diet was fed ad libitum to 10 replicates of 25 chicks in each from 1 to 42 d of age. Results: At the end of experiment, the ADG in MD group was higher than BD and lower than CD. The FE improved with FA or Bet compared to the BD. Breast meat weight was higher in Bet compared to the BD, while it was intermediate between BD and CD in other groups. The lipid peroxidation reduced with Bio, B12, or Bet, while the glutathione peroxidase activity improved with Bio or B12 compared to the BD. Lymphocyte proliferation improved with Bet compared to the BD. The serum protein concentrations increased with FA, Bio, or Bet compared to those fed BD. Conclusion: It can be concluded that the ADG can be improved partially with supplementation of MD while the FE improved with FA or Bet. Some MD also reduced the stress indices and improved immune responses compared to the BD fed broilers.

• The Journal of the Korea Contents Association
• /
• v.10 no.3
• /
• pp.301-314
• /
• 2010

The digital content industry, purred by the growth of high technology content digitization is growing in demand for content technology. The development of the digital content industry and competitive technology ensure that superior digital content is essential. National policy development through business support enables the digital content industry to pursue technology development, transfer and trade, export and industrial use of digital content and value creation to maximize the time required for project. To this end, significant public and corporate funds to strengthen competitiveness for digital content on research and development. Companies perform research and development for effective decision-making, and invest in an archive to check the efficiency and soundness of technology valuation systems in place. This research studies the development of digital content, technology, and the old methods of technology commercialization to facilitate the growth and development of digital content throughout the business world. In order to assess the value of this support, a technology valuation framework has been developed and applied to this case to validate its usefulness.

• KSII Transactions on Internet and Information Systems (TIIS)
• /
• v.17 no.6
• /
• pp.1530-1544
• /
• 2023

Data monitoring is an important foundation of modern science. In most cases, the monitoring data is time-series data, which has high application value. The deep learning algorithm has a strong nonlinear fitting capability, which enables the recognition of time series by capturing anomalous information in time series. At present, the research of time series recognition based on deep learning is especially important for data monitoring. Deep learning algorithms require a large amount of data for training. However, abnormal sample is a small sample in time series, which means the number of abnormal time series can seriously affect the accuracy of recognition algorithm because of class imbalance. In order to increase the number of abnormal sample, a data augmentation method called GANBATS (GAN-based Bi-LSTM and Attention for Time Series) is proposed. In GANBATS, Bi-LSTM is introduced to extract the timing features and then transfer features to the generator network of GANBATS.GANBATS also modifies the discriminator network by adding an attention mechanism to achieve global attention for time series. At the end of discriminator, GANBATS is adding averagepooling layer, which merges temporal features to boost the operational efficiency. In this paper, four time series datasets and five data augmentation algorithms are used for comparison experiments. The generated data are measured by PRD(Percent Root Mean Square Difference) and DTW(Dynamic Time Warping). The experimental results show that GANBATS reduces up to 26.22 in PRD metric and 9.45 in DTW metric. In addition, this paper uses different algorithms to reconstruct the datasets and compare them by classification accuracy. The classification accuracy is improved by 6.44%-12.96% on four time series datasets.

• Proceedings of the Materials Research Society of Korea Conference
• /
• 2012.05a
• /
• pp.73-73
• /
• 2012

Modern technology-driven society largely relies on hybrid electric vehicles or electric vehicles for eco-friendly transportation and the use of high technology devices. Lithium rechargeable batteries are the most promising power sources because of its high energy density but still have a challenge. Graphite is the most widely used anode material in the field of lithium rechargeable batteries due to its many advantages such as good cyclic performances, and high charge/discharge efficiency in the initial cycle. However, it has an important safety issue associated with the dendritic lithium growth on the anode surface at high charging current because the conventional graphite approaches almost 0 V vs $Li/Li^+$ at the end of lithium insertion. Therefore, a fundamental solution is to use an electrochemical redox couple with higher equilibrium potentials, which suppresses lithium metal formation on the anode surface. Among the candidates, $Li_4Ti_5O_{12}$ is a very interesting intercalation compound with safe operation, high rate capability, no volume change, and excellent cycleability. But the insulating character of $Li_4Ti_5O_{12}$ has raised concerns about its electrochemical performance. The initial insulating character associated with Ti4+ in $Li_4Ti_5O_{12}$ limits the electronic transfer between particles and to the external circuit, thereby worsening its high rate performance. In order to overcome these weak points, several alternative synthetic methods are highly required. Hence, in this presentation, novel ways using a synergetic strategy based on 1D architecture and surface coating will be introduced to enhance the kinetic property of Ti-based electrode. In addition, first-principle calculation will prove its significance to design Ti-based electrode for the most optimized electrochemical performance.

• Journal of the Korea Society of Computer and Information
• /
• v.26 no.3
• /
• pp.1-7
• /
• 2021

In this paper, optimized media data retrieval and transmission based on the Hybrid CDN/P2P architecture and selective storage through user's prediction of requestability enable seamless data transfer to users and reduction of unnecessary traffic. We also propose a new media management method to minimize the possibility of transmission delay and packet loss so that media can be utilized in real time. To this end, we construct each media into logical segments, continuously compute weights for each segment, and determine whether to store segment data based on the calculated weights. We also designate scattered computing nodes on the network as local groups by distance and ensure that storage space is efficiently shared and utilized within those groups. Experiments conducted to verify the efficiency of the proposed technique have shown that the proposed method yields a relatively good performance evaluation compared to the existing methods, which can enable both initial latency reduction and seamless transmission.

• The Journal of the Korea institute of electronic communication sciences
• /
• v.16 no.6
• /
• pp.1133-1144
• /
• 2021

Zero-copy is a technology that is also called no-memory copy, and through its use, context switching between the user space and the kernel space can be reduced to minimize the load on the CPU. However, this technology is only used to transmit small random files, and has not yet been widely used for large file transfers. This paper intends to discuss the practical application of zero-copy in processing large files via a network. To this end, we first developed a small test bed and program that can transmit and store data based on zero-copy. Afterwards, we intend to verify the usefulness of the applied technology in detail through detailed performance evaluation