• Journal of Life Science
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• v.18 no.12
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• pp.1679-1685
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• 2008

Conjugated linoleic acid (CLA) is a naturally occurring compound found in dairy and beef products. It has been shown to suppress cancer cells and to induce apoptosis. Practically, there is emerging evidence that CLA can inhibit chemically induced carcinogenesis in various tissues. However, the molecular mechanisms of CLA on human MCF-7 breast cancer cells have not been clearly explained yet. In this report, we investigated the anti-cancer activity of CLA in MCF-7 cells. It was found that CLA could inhibit the growth of the MCF-7 cells and induce apoptosis, through modulating AMP-activated protein kinase (AMPK) and cyclooxygenase-2 (COX-2). AMPK acts as a cellular fuel gauge and responds to decreased cellular energy status by inhibiting ATP-consuming pathways and increasing ATP-synthesis. CLA treatment with variable concentrations and different time of same-dose CLA on MCF-7 cells resulted in a strong activation of AMPK and an inhibition of COX-2 expression. It supports that CLA induces apoptosis in CLA-treated MCF 7 cells. Therefore, the effects of CLA induced COX-2 expression via activating AMPK can provide new possibility into the understanding the molecular mechanisms of anti-cancer component.

• Journal of Food Hygiene and Safety
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• v.28 no.2
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• pp.99-107
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• 2013

Food contaminants are an emerging issue because food is highly influential to human health. Delphi survey was performed to establish the plan for effective management of food contaminants. Fifty experts from academia, research institute, government and food industries on food safety and policy participated in this study. From open-end questions 161 topics were collected and classified into five areas and 42 topics as the first round. The five areas were 'the integrated management system on food contaminants', 'safety management of food contaminants derived from environment', 'safety management of natural toxins contaminated on foods', 'safety management of hazardous substances produced during food processing' and 'construction of cooperative system and public relationship'. At the second round, after analyzing the replies (30/50 replied) the preliminary order was obtained and it was confirmed at the third round (24/30 replied). We suggest the order of priority for required research area of food contaminants considering the importance and urgency of the research.

• Journal of Conservation Science
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• v.36 no.5
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• pp.306-314
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• 2020

The use of synthetic resins in ceramic restoration poses several challenges, including aging and potential damage to artifacts, which has raised the need to investigate new materials and restoration methods. This study set out to incorporate full color 3D printing into the 3D digital technology-based restoration method, an emerging approach currently being researched, and to print out missing parts with color information. After examining material physical properties with an experiment, the investigator printed out missing parts from a white porcelain vessel and grayish-blue-powdered celadon plate and compared them in chromaticity and brilliance. The experimental results show that the outputs had comparable tensile strength to the original restoration materials, whereas the recorded compressive strength was approximately 1.4~2 times higher than that of the original restoration materials. According to the NIST table of color difference values, the white porcelain vessel was visible at ΔE^*ab 1.55, and the grayish-blue-powdered celadon plate was perceivable at 3.34. Even though it was impossible to express the colors accurately owing to printer limitations, this non-contact approach reduced the possibility of damage to the minimum. In conclusion, it can be applied to objects with a high chance of damage or generate display effects through purposeful color differentiation in missing parts.

• Journal of Internet Computing and Services
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• v.12 no.6
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• pp.73-82
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• 2011

The location-based service is emerging again to the public attention. The location recognition environment up-to-now has been studied with its focus only on a person, an object or a moving object. However, this study proposes a location recognition model that serves to recognize and track, in real time, multiple passengers in a moving vehicle. Identifying the locations of passengers can be classified into two classes: one is to use the high price terminal with GPS function, and the other is to use the economic price compact terminal without GPS function. Our model enables the simple compact terminal to provide effective location recognition under the on-boarding situation by transmitting messages through an interface device and sensor networks for a vehicle equipped with GPS. This technology reduces transmission traffic after detecting the condition of a vehicle (being parked or running), because it does not require transmission/receiving of information on the locations of passengers who are confined in a vehicle when the vehicle is running. Also it extends battery life by saving power consumption of the compact terminal. Hence, we carried out experiments to verify its serviceability by materializing the efficient tracking system for passengers with the detection algorithm of a stopping vehicle proposed in this study. Moreover, about 200 experiments using the system designed with this technology proved successful recognition on on-boarding and alighting of passengers with the maximum transmission distance of 12 km. In addition to this, the running recognition tests showed the test with the detection algorithm of a stopping vehicle has reduced transmission traffic by 41.6% compared to the algorithm without our model.

• Journal of Internet Computing and Services
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• v.14 no.5
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• pp.119-128
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• 2013

As ICT technology becomes advanced, the importance of future internet is emphasized and in part of that, M2M (Machine-to Machine communications) is magnified in terms of importance and usage in public and private sector. M2M is emerging as a next generation strategic industry but there is no existing analyzed data or market classification, so it disrupts establishing policies on the M2M industry. As the technology is progressing, the evolution from M2M to IoT (Internet of Things) has started and many countries actively try to find technological trend through market analysis in order to develop new growth engine. Therefore, in order to strengthen competitiveness, we should secure differentiated capabilities in industry and service. This article examines Korea's domestic market and international market trends in IoT and analyses the economic impact of the IoT industry using quantitative methodology and evaluates relations between the IoT industry and other relevant industries. As a result, the effect of IoT industry on production inducement is KRW474.6 billion; the effect on value-added inducement is KRW314.7 billion; and it is measured that 3,628 jobs will be created by the IoT industry.

• Information Systems Review
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• v.6 no.2
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• pp.269-284
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• 2004

Induced from government policy to boost regional economic competitiveness, regional informatization forming e-community has been the subject included in the various regional informatization master plans in Korea. However, few cases are reported for its successful implementation mainly due to the lack of profitable business model to encourage investment. On the other hand, most efforts to build smart apartments, part of the home networking in a broad sense, has been pursued from the different directions. Telecommunication giant such as Korea Telecom tries to find new source of revenue exploiting enhanced broad band technology. Also, construction companies started constructing housing complexes equipped with built-in high speed network infrastructure as a means to differentiation to other competitors. The contents providing community portal has become mandatory in the sense of bearing the cost from customer side who are willing to adopt those services for new smart house. Our research motivation stems from exploring critical value aspects of realizing the profitability of this emerging new business model, that is, industry convergence model. In this paper, mainly from the survey results of the Korean smart apartment complexes, we reported recent home networking services development in Korea, and value propositions from the business model perspective. Merged business model components of telecommunications, construction, and internet contents are analyzed to provide the insights for future directions.

• Journal of the Korean GEO-environmental Society
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• v.16 no.8
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• pp.13-20
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• 2015

Due to the population growth and exhaustion of resource, the development on the harsh environment such as cold weather is emerging as an alternative for new resource development. The permafrost area covers about 14 percent of the world's land area and the global construction market for such area is rapidly expanded. Whereas the developed countries have already recognition of the need for research of coldest place and invested heavily in technology development, the domestic technology for the coldest place development is less developed and related research has rarely been performed. There is not a detailed national specification standard for the strength and deformation properties of the earthworks at sub-zero temperature but simple field directions. Therefore, the D compaction tests were conducted on the sand with fine contents of 0%, 5%, 10% and 15% at room temperature ($18^{\circ}C$), $-3^{\circ}C$ and $-8^{\circ}C$ to investigate the effect of the compaction energy on the compacted soils at sub-zero temperatures. Based on the test results, the larger compaction energy, the larger maximum dry unit weight under sub-zero temperature and D type compaction at $-3^{\circ}C$ show similar max. dry unit weights as those obtained from the compaction at the room temperature. However, compaction at $-8^{\circ}C$ showed significant performance degradation regardless of the compaction energy.

• Korean Journal of Plant Resources
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• v.28 no.1
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• pp.9-15
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• 2015

Methicillin-resistant Staphylococcus aureus (MRSA) has been emerging worldwide as one of the most important hospital and community pathogens. At the same time, because of the difficulty in developing chemical synthetic drugs and because of their side-effects, scientists are making more efforts to search for new drugs from plant resources to combat clinical multidrug-resistant microbial infections. Cinnamomum camphora (C. camphora) is a plant of family Lauraceae, and grown Jeju island in South Korea that are used as a drug to treat neurasthenia, epilepsy, cystitis, pyelonephritis, digitalis, cancer, and diabetes mellitus in folk remedies. In this study, antibacterial activites of 80% ethanol extract of C. camphora leaves (CCE) were investigated in combination with antibiotics against clinical isolates of MRSA. The results showed that CCE was determined with MIC and MBC values ranging from 156 to 313 and 313 to $625{\mu}g/ml$, oxacillin from 128 to 256 and 128 to $512{\mu}g/ml$, ampicillin from 4 to 64 and 8 to $128{\mu}g/ml$. The combination of CCE with oxacillin or/and ampicillin were synergistic effect against MRSA 1, 6, 7, 8, 10, 11, 12, 13, and 15/ MRSA 1, 2, 6, and 7.

• Journal of Science and Technology Studies
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• v.1 no.2 s.2
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• pp.423-438
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• 2001

The purpose of this study is to understand how a teacher's teaching can be changed while he or she teaches the same contents in different classes. The qualitative research method was used in this study. Data were collected from classroom observations, several in-depth interviews, and stimulated-recall interviews after each class. All the data were transcribed and analyzed interpretively, and then, the results of the analysis were checked by each participating teacher. The results are as follows: First, changes appeared in each class in terms of the teaching items, tools, sequence, and time, even though the same teacher taught the same contents. It showed that the teacher's teaching practice changed immediately and intuitively in class. Second, teachers tried to implement "exploratory teaching" or "move-testing teaching" to address the emerging problems during their teaching. They then reflected on and modified their own teaching. This type of change, which happened during the teaching practice, can be an example of "Reflection-in-practice." Thus, the results of this study can provide helpful insights into how teachers might adapt and reflect in their teaching. It suggests that teachers need to recognize their subconscious teaching changes and learn "Reflection-in-practice."

• The Journal of Korea Institute of Information, Electronics, and Communication Technology
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• v.9 no.1
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• pp.82-89
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• 2016

And by entering into an aging society with economic growth "beautiful and healthy desire to live', aesthetics industry as promote interest in 'Anti-aging' is emerging as a promising business increased significantly the skin care market. However, the management of the hospital or the temporal order to receive professional care providers, spatial, and cost constraints caused many companies to solve this problem began to approach the Home Care Area. Global trends in personal skin care market has been activated, the domestic has been activated at low cost, private market due to the recession. We have performed this test in order to develop a skin care device for home in order to compensate for this point.In this paper, we develop a low-level laser to create a personal skin care products and sought to incorporate them into the skin cosmetic.Expand the pores by using the low-level laser to the skin by to the dermal layer of the skin was penetrated aim experiment the ampoule, and by a comparison of the medical low-level laser reliability and determine the effectiveness or absence of the performance and efforts to commercialize.