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Analysis of Randomized Controlled Trial Study of Korean Herbal Medicine Treatment for Acne (여드름 한약 치료의 무작위 대조군 임상연구에 관한 분석)

  • Lee, Ma-Eum;Kwon, Kang;Jee, Seon-Young;Hwangbo, Min;Kim, Chul-Yun;Seo, Hyung-Sik
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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    • v.35 no.4
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    • pp.139-162
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    • 2022
  • Objectives : The review was conducted to validate the effectiveness of herbal medicines on acne. Methods : Randomized controlled trials(RCTs) reporting the effects of herbal medicine treatment on acne were searched through seven electronic databases from the time of application of the material to October 2021. Cochrane Collaboration's Risk of Bias was used to assess the risk of bias. Analysis was performed using Review Manager 5.4 and R 4.1.0 Meta, Metafor program. Results : 34 RCTs was selected and meta-analysis was performed with 30 studies. The inflammatory lesion count of the herbal medicine(MD=0.29, 95% CI:-0.59-0.01, p<0.01, I2=80%) and the non inflammatory lesion count of herbal medicine(MD=-0.30, 95% CI:-0.70-0.10, p<0.01, I2=78%) were seen. The score of IGA(RR=1.43, 95% CI:0.90-2.27, p<0.91, I2=0%), VISIA(MD=0.36, 95% CI:0.21-0.51, p=0.07, I2=40%), effective rate(RR=1.23, 95% CI:1.05-1.44, p<0.01, I2=98%), DLQI(MD : 0.59, 95% CI:0.14-1.04, p=0.07, I2=63%) and recurrence rate(RR=0.36, 95% CI:0.23-0.58, p=0.73, I2=0%) were seen. The effective rate of herbal medicine were statistically higher that of the control group(WM)(RR=1.19, 95% CI:1.04-1.37, p<0.01, I2=97%). As a result of dividing the treatment groups into OHM, EHM, and OEHM, the EHM group(RR=1.17, 95% CI:0.79-1.72, p<0.01, I2=99%) showed the most statistically significant effect. The overall risk of bias of the included studies was some concerns. No serious adverse effects were observed. Conclusions : This review found the effectiveness of herbal medicine for acne.

Domestic Clinical Research Trends of Motion-Style Acupuncture Treatment: A Scoping Review (동작침법의 국내 임상 연구 동향: 주제범위 문헌고찰)

  • Jeon, Jong-Hyeok;Woo, Hyeon-Jun;Ha, Won-Bae;Geum, Ji-Hye;Han, Yun-Hee;Park, Shin-Hyeok;Lee, Jung-Han
    • Journal of Korean Medicine Rehabilitation
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    • v.32 no.4
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    • pp.19-32
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    • 2022
  • Objectives This scoping review aimed to investigate the domestic clinical research trends of motion-style acupuncture treatment (MSAT), identify diseases and symptoms for which MSAT is used, summarize specific methods of MSAT, and suggest the direction of future studies. Methods The study was conducted in accordance with a previously specified methodology, using the preferred reporting items for systematic reviews and meta-analyses extension for scoping reviews (PRISMA-ScR) checklist. We searched nine electronic databases for studies on MSAT reported till March 21, 2022. The search terms were 'kinematic acupuncture,' 'MSAT,' 'motion style acupuncture,' and 'motion style treatment.' Results A total of 29 studies were included in our analyses; of them, 23 (79.3%) were before-after studies. Lumbosacral disease was the most common for which MSAT was applied (n=16). The frequency and duration of treatments differed depending on the researchers, and local acupoints (including ashi points) were used in 22 (75.9%) studies. In most cases, the method of mobilizing the joint or stretching the muscle in the disease area was used after inserting the acupuncture; however, in 7 studies, gait exercise was used. Most studies used MSAT in combination with other treatments. Conclusions This study supports the direction of future research by presenting the methodological applications of MSAT. To increase its clinical applicability, studies with a high level of evidence investigating the application to various body part, standardization and safety of MSAT are necessary.

Association of School Sport Club participation with Character, School Life Satisfaction, Life Attitude, and Educational Attitude among School Students in Korea: A Systematic Review (학교스포츠클럽 활동 참여와 초·중·고등학생의 인성, 학교생활만족도, 생활·학습태도의 관계: 체계적 문헌고찰)

  • Yu, Mi-seong;Song, Yoon Kyung;Kim, Ji-young;Lee, Junga;Yang, Hyuk In;Jeon, Justin Y.
    • 한국체육학회지인문사회과학편
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    • v.55 no.5
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    • pp.249-262
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    • 2016
  • The policy regarding school sport club participation that was implemented in 2007 to mitigate reductions in fitness has been reported to be satisfactory at improving the physical, mental, and social health of elementary, middle, and high school students by the students as well as by their teachers and parents. The purpose of this systematic review is to investigate the association between participation in school sport club and character-building among adolescents in Korea, and to provide evidence to inform physical education policies in the future. Using "School Sport Club" as the key word, the Korean electronic databases were searched, and this systematic review included a total of 13 articles. School sport club participation among school students is closely correlated to character-building, prevention of school violence, attitude towards life and attitude toward education. The findings of this study support the Ministry of Education's new policy (2015) to extend and expand school sport club participation and highlights the importance of physical activity.

Effectiveness of Acupuncture in the Treatment of Post-Disaster Musculoskeletal Pain: A Systematic Review (재난 후 근골격계 통증에 침치료의 유효성: 체계적 문헌고찰)

  • Ka-Hyun Kim;Sung-Won Choi;Hae-Won Hong;Ju-Young Yoon;Yong-Jun Kim;Jung-Hyun Kim
    • Journal of Korean Medicine Rehabilitation
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    • v.33 no.3
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    • pp.135-148
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    • 2023
  • Objectives To investigate the effectiveness of acupuncture in the treatment of post-disaster musculoskeletal pain by reviewing relevant clinical studies. Methods A systematic search was conducted across 10 electronic databases to identify relevant clinical studies on acupuncture treatment for post-disaster musculoskeletal pain until May 2023. The methodological quality was evaluated using the Cochrane Risk of Bias 2 and Risk of Bias Assessment tool for non-randomized studies tools. Results Six articles were analyzed, including two randomized controlled trials (RCTs), two before-after studies, one qualitative research, and one case series. Overall, acupuncture therapy showed some improvement in pain scale among musculoskeletal pain survivors. However, no significant improvement was observed in the Short-Form McGill Pain Questionnaire (SF-MPQ-2). Subgroup analysis of participants who completed at least four acupuncture sessions revealed a significant effect on the SFMPQ-2. Additionally, a significant improvement in 36-Item Short Form Survey (SF36P) was observed after 6 months of treatment, but the 2-month treatment period did not show statistically significant effects on SF-36P improvement. The evaluation of the methodological quality of the RCTs identified some concerns of bias. Conclusions The results suggest that acupuncture is effective in alleviating post-disaster musculoskeletal pain. However, considering the limited number of selected studies and the inclusion of subjective evaluation measures, caution should be exercised in interpreting the results. Further large-scale follow-up studies are needed to determine the optimal frequency and duration of acupuncture treatment. Well-designed controlled trials should be conducted to provide more robust evidence regarding the effectiveness of acupuncture for post-disaster musculoskeletal pain.

Study of MongoDB Architecture by Data Complexity for Big Data Analysis System (빅데이터 분석 시스템 구현을 위한 데이터 구조의 복잡성에 따른 MongoDB 환경 구성 연구)

  • Hyeopgeon Lee;Young-Woon Kim;Jin-Woo Lee;Seong Hyun Lee
    • The Journal of Korea Institute of Information, Electronics, and Communication Technology
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    • v.16 no.5
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    • pp.354-361
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    • 2023
  • Big data analysis systems apply NoSQL databases like MongoDB to store, process, and analyze diverse forms of large-scale data. MongoDB offers scalability and fast data processing speeds through distributed processing and data replication, depending on its configuration. This paper investigates the suitable MongoDB environment configurations for implementing big data analysis systems. For performance evaluation, we configured both single-node and multi-node environments. In the multi-node setup, we expanded the number of data nodes from two to three and measured the performance in each environment. According to the analysis, the processing speeds for complex data structures with three or more dimensions are approximately 5.75% faster in the single-node environment compared to an environment with two data nodes. However, a setting with three data nodes processes data about 25.15% faster than the single-node environment. On the other hand, for simple one-dimensional data structures, the multi-node environment processes data approximately 28.63% faster than the single-node environment. Further research is needed to practically validate these findings with diverse data structures and large volumes of data.

Research Trends in Neonatal Simulation Practice Education of Nursing Students (간호대학생의 신생아 시뮬레이션 실습교육 연구동향(2011년~2023년))

  • Sung Hee Choi;Sang Hee Kim;Sun Hui Kim
    • The Journal of the Convergence on Culture Technology
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    • v.10 no.2
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    • pp.215-224
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    • 2024
  • The purpose of this study was to examine research trends related to neonatal simulation practice education of domestic nursing students. It was a descriptive research study. For literature collection, a total of 17 journals were selected as a result of a search using ('Newborn Simulation') AND ('Nursing Student' OR 'Nursing College Student' OR 'Student Nurse') in 6 domestic electronic databases. The research results showed that it started with 7 journals from 2011 to 2015 and decreased slightly to 5 journals from 2016 to 2020 and 5 journals from 2021 to 2023. The research design was mostly quantitative with a total of 16 journals(94%). Among them, there were 15 intervention journals(88%), 1 descriptive research journals(6%), and 1 mixed method journals(6%). The key topics in simulation practice were high-risk newborns with 9 journals(52%), respiratory distress syndrome in neonatal intensive care units appeared with 3 journals(18%), neonatal care with 3 journals(18%), normal newborn care with 1 journal(6%), and neonatal emergency airway care with 1 journals(6%). The main outcome variables were clinical performance, accounting for 5 journals(19.2%), followed by practice satisfaction 3 journals(11.5%). clinical competency and practice satisfaction were found to have significant positive effects. In conclusion, various research methods are required, such as expansion of nursing students' neonatal simulation practice education, repeated research, and qualitative research.

Pharmacoacupuncture for the Treatment of Frozen Shoulder: protocol for a systematic review and meta-analysis

  • Ji-Ho Lee;Hyeon-Sun Park;Sang-Hyeon Park;Dong-Ho Keum;Seo-Hyun Park
    • Journal of Pharmacopuncture
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    • v.27 no.1
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    • pp.14-20
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    • 2024
  • Objectives: Frozen shoulder (FS) is one of the most challenging shoulder disorders for patients and clinicians. Its symptoms mainly include any combination of stiffness, nocturnal pain, and limitation of active and passive glenohumeral joint movement. Conventional treatment options for FS are physical therapy, nonsteroidal anti-inflammatory drugs, injection therapy, and arthroscopic capsular release, but adverse and limited effects continue to present problems. As a result, pharmacoacupuncture (PA) is getting attention as an alternative therapy for patients with FS. PA is a new form of acupuncture treatment in traditional Korean medicine (TKM) that is mainly used for musculoskeletal diseases. It has similarity and specificity compared to corticosteroid injection and hydrodilatation, making it a potential alternative injection therapy for FS. However, no systematic reviews investigating the utilization of PA for FS have been published. Therefore, this review aims to standardize the clinical use of PA for FS and validate its therapeutic effect. Methods: The protocol was registered in Prospero (CRD42023445708) on 18 July 2023. Until Aug. 31, 2023, seven electronic databases will be searched for randomized controlled trials of PA for FS. Authors will be contacted, and manual searches will also be performed. Two reviewers will independently screen and collect data from retrieved articles according to predefined criteria. The primary outcome will be pain intensity, and secondary outcomes will be effective rate, Constant-Murley Score, Shoulder Pain and Disability Index, range of motion, quality of life, and adverse events. Bias and quality of the included trials will be assessed using the Cochrane handbook's risk-of-bias tool for randomized trials. Meta analyses will be conducted using Review Manager V.5.3 software. GRADE will be used to evaluate the level of evidence for each outcome. Results: This systematic review and meta-analysis will be conducted following PRISMA statement. The results will be published in a peer-reviewed journal. Conclusion: This review will provide scientific evidence to support health insurance policy as well as the standardization of PA in clinical practice.

Prefetching based on the Type-Level Access Pattern in Object-Relational DBMSs (객체관계형 DBMS에서 타입수준 액세스 패턴을 이용한 선인출 전략)

  • Han, Wook-Shin;Moon, Yang-Sae;Whang, Kyu-Young
    • Journal of KIISE:Databases
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    • v.28 no.4
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    • pp.529-544
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    • 2001
  • Prefetching is an effective method to minimize the number of roundtrips between the client and the server in database management systems. In this paper we propose new notions of the type-level access pattern and the type-level access locality and developed an efficient prefetchin policy based on the notions. The type-level access patterns is a sequence of attributes that are referenced in accessing the objects: the type-level access locality a phenomenon that regular and repetitive type-level access patterns exist. Existing prefetching methods are based on object-level or page-level access patterns, which consist of object0ids of page-ids of the objects accessed. However, the drawback of these methods is that they work only when exactly the same objects or pages are accessed repeatedly. In contrast, even though the same objects are not accessed repeatedly, our technique effectively prefetches objects if the same attributes are referenced repeatedly, i,e of there is type-level access locality. Many navigational applications in Object-Relational Database Management System(ORDBMs) have type-level access locality. Therefore our technique can be employed in ORDBMs to effectively reduce the number of roundtrips thereby significantly enhancing the performance. We have conducted extensive experiments in a prototype ORDBMS to show the effectiveness of our algorithm. Experimental results using the 007 benchmark and a real GIS application show that our technique provides orders of magnitude improvements in the roundtrips and several factors of improvements in overall performance over on-demand fetching and context-based prefetching, which a state-of the art prefetching method. These results indicate that our approach significantly and is a practical method that can be implemented in commercial ORDMSs.

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Pain Reduction Effects of Lidocaine Gel for Urethral Catheterization : A Systematic Review and Meta-Analysis (요도 카테터 삽입술에서 리도카인 윤활제의 통증 감소 효과 : 체계적 문헌고찰과 메타분석)

  • Hong, Hyun-Jung;Kim, Ga-Eun;Lee, Ha-Nee;Lee, A-Reum
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.18 no.6
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    • pp.438-448
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    • 2017
  • This study was a systematic review and meta-analysis that evaluated the results of research on the pain reduction effects of lidocaine gel for urethral catheterization in adults. A literature search was conducted using seven electronic databases, gray literature and other resources based on the guidelines of Preferred Reporting Items for Systematic review and Meta-Analysis (PRISMA). A Risk of Bias (RoB) tool was applied to assess the quality of selected studies. Data were analyzed using the RevMan 5.3.-program. Sixteen randomized controlled trials involving 1904 adults were included. RoB was not observed in the funnel plot. Overall, lidocaine gel was effective for pain reduction during urethral catheterization (Standard Mean Difference[SMD] -0.96;95% CI: -1.43, -0.49). To explore the cause of heterogeneity (I2=95%, p<.001), subgroup analysis was conducted according to three catheter types (urinary catheter, flexible cystoscopy, and rigid cystoscopy) and the SMDs were -0.88 (95% CI:-1.51, -0.26), -0.31 (95% CI:-0.63, 0.01), and -1.93 (95% CI:-2.88, -0.97), respectively. A significant pain reduction effect was observed regardless of gender in urinary catheterization. However, in rigid cystoscopy, a significant pain reduction effect was observed only in male subjects. Pain reduction effects were observed when 10~11ml lidocaine gel was used during rigid cystoscopy and when lubrication was used during urinary catheterization, irrespective of application time. These findings suggest that lidocaine gel is a useful anesthetic lubricant for urinary catheterization and rigid cystoscopy in male adults.

Herbal Medicine for the Treatment of Rosacea: A Systematic Review and Meta-analysis of Randomized Controlled Trials (주사(Rosacea)의 한약 치료에 대한 체계적 문헌고찰 및 메타분석)

  • Kang, Eun-Jeong;Kam, Eun-Young;Kim, Seo-Hee;Yoon, Seok-Yeong;Jeon, Seok-Hee;Choi, Jung-Wha;Kim, Jong-Han;Park, Soo-Yeon;Jung, Min-Yeong
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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    • v.34 no.3
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    • pp.27-54
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    • 2021
  • Objectives : This review was conducted to validate the effectiveness and safety of herbal medicine combined with conventional therapy for rosacea. Methods : Randomized controlled trials(RCTs) reporting the effects of herbal medicine treatment on rosacea were searched through eight electronic databases from 2016 to March 17, 2020. This study collection and data extraction were performed by two independent reviews. The Cochrane risk-of-bias tool was used for the evaluation of the risk of bias in all included RCTs. Mean differences(MD) and Risk ratio(RR) of 95% Confidence intervals(Cls) were calculated and data synthesis was conducted using Review Manager(RevMan, ver.5.4) Results : Eighteen RCTs were included and all trials compared the combined therapy of herbal medicine with conventional western therapy to conventional therapy alone. The effective rate of the combination of herbal medicine with western medicine(RR 1.20, 95% CI : 1.13-1.28, p<0.00001, I2=0%), the effective rate of the combination of herbal medicine with laser-based therapy(RR 1.12, 95% CI : 1.04-1.21, p=0.004, I2=18%) and the effective rate of the combination treatment group using herbal medicine, western medicine and external drugs were all statistically higher that of the control group(RR 1.19, 95% CI : 1.11-1.28, p<0.00001, I2=0%). The score of non transient erythema(MD -0.36, 95% CI : -1.01 0.29, p=0.27, I2=93%), flushing(MD -0.69, 95% CI : -0.97, 0.41, p<0.00001, I2=32%), papules or pustules(MD 0.10, 95% CI : -0.15, 0.35 p=0.44, I2=0%) were also seen in the herbal medicine and western medicine combination group. The overall risk of bias of the included studies was some concerns. No serious adverse effects were observed. Conclusions : This review found the safety and effectiveness of the combined therapy of herbal medicine with conventional western therapy for rosacea.