• Radiation Oncology Journal
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• v.9 no.1
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• pp.123-130
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• 1991

A docking intraoperative electron beam applicator system, which is easily docking in the collimator for a linear accelerator after setting a sterilized transparent cone on the tumor bearing area in the operation room, has been designed to optimize dose distribution and to improve the efficiency of radiation treatment method with linear accelerator. This applicator system consisted of collimator holder with shielded metals and docking cone with transparent acrylic cylinder, A number of technical innovations have been used in the design of this system, this dooking cone gives a improving latral dose coverage at therapeutic volume. The position of $90\%$ isodose curve under suface of 8 cm diameter cone was extended $4\sim7$ mm at 12 MeV electron and the isodose measurements beneath the cone wall showed hot spots as great as $106\%$ for acrylic cone. The leakage radiation dose to tissues outside the cone wall was reduced as $3\sim5\%$ of output dose. A comprehensive set of dosimetric characteristics of the intraoperative radiation therapy applicator system is presented.

• The Journal of Korean Academy of Prosthodontics
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• v.29 no.2
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• pp.245-265
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• 1991

The purpose of this study was to observe the changes of the elemental transmission and bond strength between the metal and porcelain according to various kinds of ion beam mixing method. ion beam mixing of $meta1/SiO_2$ (silica), $meta1/Al_2O_3$(alumina) interfaces causes reactions when the $Ar^+$ was implanted into bilayer thin films using a 100KeV accelerator which was designed and constructed for this study. A vacuum evaporator used in the $10^{-5}-10^{-6}$ Torr vacuum states for the evaporation. For this study, three kinds of porcelain metal selected, -precious, semiprecious, and non-precious. Silica and alumina were deposited to the metal by the vacuum evaporator, separately. One group was treated by two kinds of dose of the ion beam mixing $(1\times10^{16}ions/cm^2,\;5\times10^{15}ions/cm^2)$, and the other group was not mixed, and analyzed the effects of ion beam mixing. The analyses of bond strength, elemental transmissions were performed by the electron spectroscopy of chemical analysis (ESCA), light and scanning electron microscope, scratch test, and micro Vickers hardness tests. The finding led to the following conclusions. 1. In the scanning electron and light microscopic views, ion beam mixed specimens showed the ion beam mixed indentation. 2. In the micro Vickers hardness and scratch tests, ion beam mixed specimens showed higher strength than that of non mixed specimens, however, nonprecious metal showed a little change in the bond strength between mixed and non mixed specimens. 3. In the scratch test, ion beam mixed specimens showed higher shear strength than that of non treated specimens at the precious and semiprecious groups. 4. In the ESCA analysis, Au-O and Au-Si compounds were formed and transmission of the Au peak was found ion beam mixed $SiO_2/Au$ specimen, simultaneously, in the higher and lower bonded areas, and ion beam mixed $SiO_2/Ni-Cr$ specimen, oxygen, that was transmitted from $SiO_2\;to\;SiO_2/Ni-Cr$ interface combined with 12% of Ni at the interface.

• Applied Microscopy
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• v.22 no.2
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• pp.1-14
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• 1992

This experiment was performed to study the morphological responses of the parafollicular cells of rat following X-ray irradiation. Male rats were divided into normal and experimental groups. The head and neck region of the rat, under sodium thiopental anesthesia, was exposed to 3,000 rads or 6,000 rads of radiation in a single dose, respectively. The source was a Mitsubishi Linear Accelerator ML-4MV. The target to skin distance was 80 cm, and the dose rate was 200 rads/min. The rate of experimental groups were sacrificed on the 6th hour, 2nd and 6th day after X-ray irradiation. Pieces of the tissue taken from the thyroid gland were fixed in 2.5% glutaraldehyde-1.5% paraformaldehyde (0.1M Millonig's phosphate buffer, pH 7.3), and in 1% osmium tetroxide (0.1M Millonig's phosphate buffer, pH 7.3), and embedded in araldite mixture. The ultrathin sections stained with uranyl acetate and lead citrate were observed with JEM 100 CX-II electron microscope. The results were as follow; 1. Two types of the parafollicular cells, according to their electron densities, were found, i. e., light cells and dark cells. 2. Three types of the parafollicular cells, according to their sizes of secretory granules were found, i.e., small granule cells ($85nm{\pm}20.1;64{\sim}102nm$), medium granule cells ($120nm{\pm}26.5;77{\sim}179nm$), and large granule cells ($165nm{\pm}25.7;128{\sim}189nm$). 3. The differential ultrastructural changes of the cells according to their cell types, i.e., dark and light cell, or small, medium and large granule cells, were hardly observed in the time and dose range covered by this study. 4. The morphological changes of the parafollicular cells were not pronounced after exposure to 3,000 rads of X-ray. 5. Swollen cisternae of the granular endoplasmic reticulum and partial cytolysis were observed after exposure to 6,000 rads of X-ray. 6. Above results suggest that the parafollicular cells showed the alterations of mitochondrial and granular endoplasmic reticular swelling, and partial cytolysis, but only in doses of 6,000 rads.

• Journal of the Korean Vacuum Society
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• v.16 no.6
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• pp.474-478
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• 2007

Nanostructures of $SiN_x$ were made by bombardment of ionized $N_2$ on Si surface and subsequent annealing. Atomic force micrograph showed the density of $SiN_x$ nanostructures was $3\times10^{10}/cm^2$. Their lateral size and height were 40$\sim$60 nm and 15 nm, respectively. The chemical state of the nanostructure was measured using X-ray photoelectron spectroscopy, which changed from $SiN_x$ to $Si_3N_4\;+\;SiN_x$ as the bombarding ionized gas current increases. Upon annealing, transmission electron micrograph showed a clear evidence for crystalline Si phase formation inside the $SiN_x$ nanostructures. Photoluminescence peak observed at around 400nm was thought to be originated from the interface states between the nanocrystalline Si and surrounding $SiN_x$ nanostructures.

• Journal of Korea Foresty Energy
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• v.22 no.2
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• pp.69-77
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• 2003

This study reviewed antioxidants and various enzymic physiological functions of Korean ash tree extractives that contains coumarine and ester component in order to examine the practical possibility of those materials as pharmaceutical and cosmetic additive applications. first, in the experiment of enzymic physiological activity, the electron donating ability showed 62.00% at 1ppm and over 90% at 10ppm or higher concentration, and the pseudo SOD ability showed 39% at the concentration of 2000ppm and 84.73% at the concentration of 5000ppm. Second, the inhibition activity of xanthine oxidase showed a relatively low inhibition effect of 45.57% at 200ppm, and the inhibition effect of tyrosinase showed 57.51% at 2000ppm. However, it showed a very low inhibition effect at the concentration of 500ppm or less. Third, the lipid oxidation, when Cu$\^$2＋/ion was used as an oxidation accelerator, showed the inhibition effect of 82% at the concentration of 10ppm, and when Fe$\^$2＋/ion was used also as the oxidation accelerator, it showed a very outstanding effect of 60% and more at 100ppm. Conclusively it is clear that the extracts of Korean ash tree bark can be used as cosmetic and pharmaceutical additive agents due to their excellent activities as antioxidant and enzymic physiological functions of it.

• The Journal of Korean Society for Radiation Therapy
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• v.29 no.2
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• pp.65-73
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• 2017

Purpose: Machine Performance Check (MPC) is a self-checking software based on the Electronic Portal Imaging Device (EPID) to measure daily beam outputs without external installation. The purpose of this study is to verify the usefulness of MPC by comparing and correlating daily beam output of QA Beamchecker PLUS. Materials and Methods: Linear accelerator (Truebeam 2.5) was used to measure 10 energies which are composed of photon beams(6, 10, 15 MV and 6, 10 MV-FFF) and electron beams(6, 9, 12, 16 and 20 MeV). A total of 80 cycles of data was obtained by measuring beam output measurement before treatment over five months period. The Pearson correlation coefficient was used to evaluate the consistency of the beam output between the MPC and the QA Beamchecker PLUS. In this study, if the Pearson correlation coefficient is; (1) 0.8 or higher, the correlation is very strong (2) between 0.6 and 0.79, the correlation is strong (3) between 0.4 and 0.59, the correlation is moderate (4) between 0.2 and 0.39, the correlation is weak (5) lower than 0.2, the correlation is very weak. Results: Output variations observed between MPC and QA Beamchecker PLUS were within 2 % for photons and electrons. The beam outputs variations of MPC were $0.29{\pm}0.26%$ and $0.30{\pm}0.26%$ for photon and electron beams, respectively. QA Beamchecker PLUS beam outputs were $0.31{\pm}0.24%$ and $0.33{\pm}0.24%$ for photon and electron beams, respectively. The Pearson correlation coefficient between MPC and QA Beamchecker PLUS indicated that photon beams were very strong at 15 MV, and strong at 6 MV, 10 MV, 6 MV-FFF and 10 MV-FFF. For electron beams, the Pearson correlation coefficient were strong at 16 MeV and 20 MeV, moderate at 9 MeV and 12 MeV, and very weak at 6 MeV. Conclusion: MPC showed significantly strong correlation with QA Beamchecker PLUS when testing with photon beams and high-energy electron beams in the evaluation of daily beam output, but the correlation when testing with low-energy electron beams (6 MeV) appeared to be low. However, MPC and QA Beamchecker PLUS are considered to be suitable for checking daily beam output, as they performed within 2 % of beam output consistency during the observation. MPC which can perform faster than the conventional daily beam output measurement tool, is considered to be an effective method for users.

• Journal of the Korean Society of Radiology
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• v.4 no.4
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• pp.29-32
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• 2010

The neutron capture cross section of $^{197}Au$ has been measured relative to the $^{10}B(n,{\gamma})$ standard cross section by the neutron time-of-flight(TOF) method using a 46-MeV electron linear accelerator(linac) at the Research Reactor Institute, Kyoto University(KURRI). In order to experimentally prove the result obtained, the supplementary cross section measurement has been made from 0.1 eV to 10 keV using the Kyoto University Lead slowing-down spectrometer (KULS) coupling to the linac. The relative measurement by the TOF method has been normalized to the reference value(24.5 b) at 1 eV. The evaluated capture cross sections in JENDL/D-99 Dosimetry have been compared with the current measurements by the KULS experiments.

• Polymer(Korea)
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• v.27 no.3
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• pp.242-248
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• 2003

PP-g-(AN/Sty) was synthesized by grafting with acrylonitrile (AN) and styrene (Sty) onto PP staple fiber using an electron beam accelerator and followed by amidoximination and phosphorylation. Mole fraction of AN in the graft chain increased with the increase of the AN content in the monomer mixture. The highest AN grafting yield of 45% was obtained at a monomer ratio of 40 vol% AN/60 vol% Sty. Mole fraction of AN in the graft chain decreased with the increase of methanol amount used its solvent. As reaction temperature increased, the grafting yield of copolymer increased and reached equilibrium at 50$^{\circ}C$. Amount of amidoxime group in fibrous ion exchanger was increased as increasing amount of hydroxylamine, and the maximum content of amidoxime group was observed at 5.8 mmol/g with the 9 wt% hydroxylamine concentration. Content of phosphorous group in fibrous ion exchanger increased up to 0.5 N phosphoric acid concentration, and then leveled off. The adsorption ability of the copolymer for uranyl ion by the chelating adsorbents was in the following order : bifunctional PP-g-(AN/sty) > amidoximated PP-g-(AN/Sty) > phosphorylated PP-g-(AN/Sty).

• Journal of radiological science and technology
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• v.41 no.2
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• pp.141-148
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• 2018

This study examined the properties of photons and the dose distribution in a human body via a simulation where the total body irradiation(TBI) is performed on a pediatric anthropomorphic phantom and a child size water phantom. Based on this, we tried to find the optimal photon beam energy and material for beam spoiler. In this study, MCNPX (Ver. 2.5.0), a simulation program based on the Monte Carlo method, was used for the photon beam analysis and TBI simulation. Several different beam spoiler materials (plexiglass, copper, lead, aluminium) were used, and three different electron beam energies were used in the simulated accelerator to produce photon beams (6, 10, and 15 MeV). Moreover, both a water phantom for calculating the depth-dependent dosage and a pediatric anthropomorphic phantom for calculating the organ dosage were used. The homogeneity of photon beam was examined in different depths for the water phantom, which shows the 20%-40% difference for each material. Next, the org an doses on pediatric anthropomorphic phantom were examined, and the results showed that the average dose for each part of the body was skin 17.7 Gy, sexual gland 15.2 Gy, digestion 13.8 Gy, liver 11.8 Gy, kidney 9.2 Gy, lungs 6.2 Gy, and brain 4.6 Gy. Moreover, as for the organ doses according to materials, the highest dose was observed in lead while the lowest was observed in plexiglass. Plexiglass in current use is considered the most suitable material, and a 6 or 10 MV photon energy plan tailored to the patient condition is considered more suitable than a higher energy plan.

• Proceedings of the Materials Research Society of Korea Conference
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• 2011.05a
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• pp.239.2-239.2
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• 2011

치과재료의 개발은 치과 치료 기술에 있어서 가장 중요한 요소이며, 현재 일반화되고 있는 치과 치료 기술 중 하나가 임플란트 시술이다. 임플란트의 기술 개발은 주로 임플란트 나사의 표면개질을 통한 기능개선에 초점을 ��추어 진행되어지고 있다. 본 연구에서는 Ti 임플란트 표면상에 양극산화법을 적용하여 다양한 지름 및 기공 크기를 갖는 $TiO_2$ 나노튜브를 제조하여 전자빔 조사를 통한 표면개질시 그 특성에 관한 연구를 수행하였다. 특히 전자빔 조사가 Ti/$TiO_2$ 나노튜브 표면상에 존재 가능한 조골세포의 성장 특성에 미치는 영향을 연구하였다. 양극산화법을 이용한 Ti/$TiO_2$ 나노튜브는 전해질로서 HF와 $NH_4F$를 사용하였으며, 20-80 V의 인가 전압하에서 내경 약 80 nm, 외경 약 124 nm 및 길이 약 280 nm-14 ${\mu}m$의 비교적 균질한 지름 및 분포를 갖는 Ti/$TiO_2$ 나노튜브를 제조하였다. 전자빔 조사는 EB-Tech (대전, 한국)의 electron-beam accelerator(Model ELV-4)를 이용하였으며, 1.0 MeV의 빔 에너지로 총 흡수선량이 50 kGy, 500 kGy 및 5,000 kGy로 조사하였다. 전자빔을 조사하기 전 후 Ti/$TiO_2$ 나노튜브 표면상에 조골세포주(Osteoblast cell)의 배양시간의 변화에 따른 효과를 연구한 결과 배양 전 후 전자빔 조사선량의 증가에 따라 조골세포의 흡착률이 증가함을 확인할 수 있었다. 특히 HF전해질을 이용한 $TiO_2$ 나노튜브의 경우 5,000 kGy 조사선량의 전자빔을 조사한 후 조골세포 흡착률이 약 160% 증가하는 결과를 얻을 수 있었다. 전자빔 조사 전 후 조골세포 흡착률의 변화원인은 전자빔 조사 유무에 따른 $Ti^{3+}$와 $Ti^{4+}$의 변화에 기인함을 규명하였다. 이러한 결과는 향후 임플란트용 Ti/$TiO_2$ 나노튜브의 표면 개질시 전자빔의 유용성을 제시한다고 할 수 있다.