• Journal of Information Display
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• v.4 no.2
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• pp.13-18
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• 2003

We synthesized bis (2-methyl-8-quinolinolato)(triphenylsiloxy) aluminum (III) (SAlq), a blue-emitting material having a high luminous efficiency, through a homogeneous-phase reaction. The photoluminescence (PL) and electroluminescence (EL) spectra of SAlq show two peaks at 454 nm and 477 nm. Efficient white light-emitting devices are fabricated by doping SAlq with a red fluorescent dye of 4-dicyanomethylene-2-methyl-6-{2-(2,3,6,7-tetrahydro-1H,5H-benzo[i,j]quinolizin-8yl) vinyl}-4H-pyran (DCM2). The incomplete energy transfer from blue-emitting SAlq to red-emitting DCM2 results in light-emission of both blue and orange colors. Devices with the structure of ITO/TPD (50 nm)/SAlq:DCM2 (30 nm, 0.5 %)/$Alq_3$ (20 nm)/LiF (0.5 nmj/Al show EL peaks at 456 nm and 482 nm originating from SAlq and at 570 nm from DCM2, resulting in the Commission Internationale d'Eclairage (CIE) chromaticity coordinates of (0.32, 0.37). The device exhibits an external quantum efficiency of about 2.3 % and a luminous efficiency of about 2.41m/W at 100 $cd/m^2$. A maximum luminance of about 23,800 $cd/m^2$ is obtained at the bias voltage of 15 V.

• Food Science and Biotechnology
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• v.17 no.4
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• pp.761-765
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• 2008

Bacillus cereus causes two different types of food poisoning syndromes: diarrhea and emesis. The diarrheal syndrome is attributed to various enterotoxins, including nonhemolytic enterotoxin, hemolytic enterotoxin, and enterotoxin-T, whereas the emetic syndrome is caused by the dodecadepsipeptide toxin cereulide. A multiplex polymerase chain reaction (PCR) assay was developed to rapidly detect and identify B. cereus strains. Three primer pairs specific to regions within genes encoding nonhemolytic enterotoxin (nheA), molecular chaperonin (groEL), and cereulide synthetase (ces) were used to identify and differentiate between the enterotoxin-producing and emetic toxin-producing B. cereus strains. The cereulide-producing emetic B. cereus showed 3 PCR products of 325, 405, and 685 bp for the groEL, ces, and nheA genes, respectively, whereas the enterotoxin-producing B. cereus showed 2 PCR products without a ces gene specific DNA fragment. Specific amplifications and differentiations by multiplex PCR assay were obtained using 62 B. cereus strains and 13 strains' of other bacterial species. The detection limit of this assay for enterotoxin-producing strain and emetic toxin-producing strain from pure cultures were $2.4{\times}10^1$ and $6.0{\times}10^2\;CFU/tube$, respectively. These results suggest that our multiplex PCR method may be useful for the rapid detection and differentiation of B. cereus strains in foods.

• Steel and Composite Structures
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• v.46 no.1
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• pp.75-92
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• 2023

The novel composite cold-formed steel (CFS)/engineered cementitious composites (ECC) beams have been recently presented. The new composite section exhibited superior structural performance as a flexural member, benefiting from the lightweight thin-walled CFS sections with improved buckling and torsional properties due to the restraints provided by thinlayered ECC. This paper investigated the shear performance of the new composite CFS/ECC section. Twenty-eight simply supported beams, with a shear span-to-depth ratio of 1.0, were assembled back-to-back and tested under a 3-point loading scheme. Bare CFS, composite CFS/ECC utilising ECC with Polyethylene fibres (PE-ECC), composite CFS/MOR, and CFS/HSC utilising high-strength mortar (MOR) and high-strength concrete (HSC) as replacements for PE-ECC were compared. Different failure modes were observed in tests: shear buckling modes in bare CFS sections, contact shear buckling modes in composite CFS/MOR and CFS/HSC sections, and shear yielding or block shear rupture in composite CFS/ECC sections. As a result, composite CFS/ECC sections showed up to 96.0% improvement in shear capacities over bare CFS, 28.0% improvement over composite CFS/MOR and 13.0% over composite CFS/HSC sections, although MOR and HSC were with higher compressive strength than PE-ECC. Finally, shear strength prediction formulae are proposed for the new composite sections after considering the contributions from the CFS and ECC components.

• The Korean Journal of Physiology and Pharmacology
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• v.28 no.3
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• pp.275-284
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• 2024

Worldwide, cardiovascular disease is the main cause of death, which accordingly increased by hyperlipidemia. Hyperlipidemia therapy can include lifestyle changes and medications to control cholesterol levels. Statins are the medications of the first choice for dealing with lipid abnormalities. Rosuvastatin founds to control high lipid levels by hindering liver production of cholesterol and to achieve the targeted levels of low-density lipoprotein cholesterol, another lipid lowering agents named ezetimibe may be used as an added therapy. Both rosuvastatin and ezetimibe have low bioavailability which will stand as barrier to decrease cholesterol levels, because of such depictions, formulations of this combined therapy in nanotechnology will be of a great assistance. Our study demonstrated preparations of nanoparticles of this combined therapy, showing their physical characterizations, and examined their behavior in laboratory conditions and vivo habitation. The mean particle size was uniform, polydispersity index and zeta potential of formulations were found to be in the ranges of (0.181-0.72) and (-13.4 to -6.24), respectively. Acceptable limits of entrapment efficiency were affirmed with appearance of spherical and uniform nanoparticles. In vitro testing showed a sustained release of drug exceeded 90% over 24 h. In vivo study revealed an enhanced dissolution and bioavailability from loaded nanoparticles, which was evidenced by calculated pharmacokinetic parameters using triton for hyperlipidemia induction. Stability studies were performed and assured that the formulations are kept the same up to one month. Therefore, nano formulations is a suitable transporter for combined therapy of rosuvastatin and ezetimibe with improvement in their dissolution and bioavailability.

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.9
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• pp.4815-4822
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• 2012

Invasion and metastasis are the major causes of cancer-related death. Pharmacological or therapeutic interventions such as chemoprevention of the progression stages of neoplastic development could result in substantial reduction in the incidence of cancer mortality. (-)-Epigallocatechin-3-gallate (EGCG), a promising chemopreventive agent, has attracted extensive interest for cancer therapy utilizing its antioxidant, anti-proliferative and inhibitory effects on angiogenesis and tumor cell invasion. In this study, we assessed the influence of EGCG on the proliferative potential of HeLa cells by cell viability assay and authenticated the results by nuclear morphological examination, DNA laddering assay and cell cycle analysis. Further we analyzed the anti-invasive properties of EGCG by wound migration assay and gene expression of MMP-9 and TIMP-1 in HeLa cells. Our results indicated that EGCG induced growth inhibition of HeLa cells in a dose- and time-dependent manner. It was observed that cell death mediated by EGCG was through apoptosis. Interestingly, EGCG effectively inhibited invasion and migration of HeLa cells and modulated the expression of related genes (MMP-9 and TIMP-1). These results indicate that EGCG may effectively suppress promotion and progression stages of cervical cancer development.

• Steel and Composite Structures
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• v.13 no.1
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• pp.91-107
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• 2012

In this research, mechanical buckling of hybrid functionally graded plates is considered using a new four variable refined plate theory. Unlike any other theory, the number of unknown functions involved is only four, as against five in case of other shear deformation theories. The theory presented is variationally consistent, does not require shear correction factor, and gives rise to transverse shear stress variation such that the transverse shear stresses vary parabolically across the thickness satisfying shear stress free surface conditions. The plate properties are assumed to be varied through the thickness following a simple power law distribution in terms of volume fraction of material constituents. Governing equations are derived from the principle of minimum total potential energy. The closed-form solution of a simply supported rectangular plate subjected to in-plane loading has been obtained by using the Navier method. The effectiveness of the theories is brought out through illustrative examples.

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.4
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• pp.1081-1091
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• 2012

Myelodysplastic syndromes (MDS) represent a heterogeneous group of clonal hematologic neoplasms characterized by morphologic dysplasia, aberrant hematopoiesis and peripheral blood refractory cytopenias. MDS is recognized to be associated with an increased risk of symptomatic anemia, infectious complications and bleeding diathesis, as well as a risk of progression to acute myeloid leukemia, particularly in patients with a high IPSS score. The advent of use of hematopoietic growth factors such as granulocyte colony-stimulating factor (G-CSF) and recombinant erythropoietin (EPO) has improved symptoms in MDS patients in addition to some data that suggest there might be an improvement in survival. G-CSF is an effective therapeutic option in MDS patients, and it should be considered for the management of refractory symptomatic cytopenias. G-CSF and EPO in combination can improve outcomes in appropriate MDS patients such as those with lower-risk MDS and refractory anemia with ring sideroblasts (RARS). This article reviews use of growth factors for lower-risk MDS patients, and examines the data for G-CSF, EPO and thrombopietic growth factors (TPO) that are available or being developed as therapeutic modalities for this challenging disease.

• Carbon letters
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• v.13 no.4
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• pp.212-220
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• 2012

Orange peel (OP) exhibits a sorption capacity towards anionic dyes such as reactive blue 19 (RB19). Cetyltrimethylammonium bromide (CTAB) as a cationic surfactant was used to modify the surface nature of OP to enhance its adsorption capacity for anionic dyes from an aqueous solution. Four adsorbents were investigated: the OP, sodium hydroxide-treated OP (SOP), CTAB-modified OP and CTAB-modified SOP. The physical and chemical properties of these sorbents were determined using nitrogen adsorption at 77 K and by scanning electron microscope and Fourier transform infrared spectroscopy techniques. The adsorption of the RB19 dye was assessed with these sorbents at different solution pH levels and temperatures. The effect of the contact time was considered to determine the order and rate constants of the adsorption process. The adsorption data were analyzed considering the Freundlich, Langmuir, Elovich and Tempkin models. The adsorption of RB19 by the assessed sorbents is of the chemisorption type following pseudo-first-order kinetics. CTAB modification brought about a significant increase in RB19 adsorption, which was ascribed to the grafting of the sorbent with a cationic surfactant.

• Journal of Electrical Engineering and Technology
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• v.13 no.2
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• pp.742-751
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• 2018

Electric vehicles (EV) are emerging as the future transportation vehicle reflecting their potential safe environmental advantages. Vehicle to Grid (V2G) system describes the hybrid system in which the EV can communicate with the utility grid and the energy flows with insignificant effect between the utility grid and the EV. The paper presents an optimal power control and energy management strategy for Plug-In Electric Vehicle (PEV) charging stations using Wind-PV-FC-Battery renewable energy sources. The energy management optimization is structured and solved using Multi-Objective Particle Swarm Optimization (MOPSO) to determine and distribute at each time step the charging power among all accessible vehicles. The Model-Based Predictive (MPC) control strategy is used to plan PEV charging energy to increase the utilization of the wind, the FC and solar energy, decrease power taken from the power grid, and fulfil the charging power requirement of all vehicles. Desired features for EV battery chargers such as the near unity power factor with negligible harmonics for the ac source, well-regulated charging current for the battery, maximum output power, high efficiency, and high reliability are fully confirmed by the proposed solution.

• Wind and Structures
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• v.13 no.5
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• pp.451-469
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• 2010

The majority of weather-related failures of transmission line structures that have occurred in the past have been attributed to high intensity localized wind events, in the form of tornadoes and downbursts. A numerical scheme is developed in the current study to assess the performance of transmission lines under tornado wind load events. The tornado wind field is based on a model scale Computational Fluid Dynamic (CFD) analysis that was conducted and validated in a previous study. Using field measurements and code specifications, the CFD model data is used to estimate the wind fields for F4 and F2 full scale tornadoes. The wind forces associated with these tornado fields are evaluated and later incorporated into a nonlinear finite element three-dimensional model for the transmission line system, which includes a simulation for the towers and the conductors. A comparison is carried between the forces in the members resulting from the tornadoes, and those obtained using the conventional design wind loads. The study reveals the importance of considering tornadoes when designing transmission line structures.