New product innovation is a process of embodying new knowledge in a product and technology licensing is getting popular as a means to innovations and introduction of new product to the market in today's competitive global market environment. Incumbents often rely on technology licensing to access new product opportunities created by other firms. Prior research has examined various aspects of technology licensing agreements such as specific contract terms of licensing agreements, e.g., distribution of control rights, exclusivity of licensing agreements, cross-licensing, and the scope of licensing agreements. This study aims to provide answers to an important, but under-researched question: why do some incumbents initiate more licensing agreement for exploratory learning while others do it for exploitative learning along the innovation process? We attempt to extend our knowledge of licensing agreements from an organizational learning perspective. Technology licensing as a specific form of interfirm linkages can be initiated with different learning objectives along the process of new product innovation. The exploratory stages of the innovation process such as discovery or research stages involve extensive searches to create new knowledge or capabilities, whereas the exploitative stages of the innovation process such as application or test stages near the commercialization are more focused on developing specific applications or improving their efficiency or reliability. Thus, different stages of the innovation process generate different types of learning and the resulting technological resources. We examine when incumbents as licensees initiate more licensing agreements for exploratory learning objectives and when more for exploitative learning objectives, focusing on two factors that may influence a firm's formation of exploratory and exploitative licensing agreements: 1) its past radical and incremental innovation experience and 2) its internal investments in R&D and marketing. We develop and test our hypotheses regarding the relationship between a firm's radical and incremental new product experience, R&D investment intensity and marketing investment intensity, and the likelihood of engaging in exploratory and exploitive licensing agreements. Using data collected from various secondary sources (Recap database, Compustat database, and FDA website), we analyzed technology licensing agreements initiated in the biotechnology and pharmaceutical industries from 1988 to 2011. The results of this study show that incumbents initiate exploratory rather than exploitative licensing agreements when they have more radical innovation experience and when they invest in R&D activities more intensively; in contrast, they initiate exploitative rather than exploratory licensing agreements when they have more incremental innovation experience and when they invest in marketing activities more intensively. The findings of this study contribute to the licensing and interfirm cooperation studies. First, this study lays a foundation to understand the organizational learning aspect of technology licensing agreements. Second, this study sheds lights on how a firm's internal investments in R&D and marketing are linked to its tendency to initiate licensing agreements along the innovation process. Finally, the findings of this study provide important insight to managers regarding which technologies to gain via licensing agreements. This study suggests that firms need to consider their internal investments in R&D and marketing as well as their past innovation experiences when they initiate licensing agreements along the process of new product innovation.
The effects of three different feeding systems on beef cattle production performance, rumen fermentation, and rumen digesta particle structure were investigated by using 18 Limousin (steers) with a similar body weight ($575{\pm}10kg$) in a 80-d experiment. The animals were equally and randomly divided into three treatment groups, namely, total mixed ration group (cattle fed TMR), SI1 group (cattle fed concentrate firstly then roughage), and SI2 group (cattle fed roughage firstly then concentrate). The results showed that the average daily gain was significantly higher in cattle receiving TMR than in those receiving SI1 and SI2 (p<0.05). Consumption per kg weight gain of concentrate, silage, and combined net energy (NEmf) were significantly decreased when cattle received TMR, unlike when they received SI1 and SI2 (p<0.05), indicating that the feed efficiency of TMR was the highest. Blood urea nitrogen (BUN) was significantly decreased when cattle received TMR compared with that in cattle receiving SI1 (p<0.05), whereas there was no difference compared with that in cattle receiving SI2. Ammonia nitrogen concentration was significantly lower in cattle receiving TMR than in those receiving SI1 and SI2 (p<0.05). The rumen area of cattle that received TMR was significantly larger than that of cattle receiving SI1 (p<0.05), but there was no difference compared with that of cattle receiving SI2. Although there was no significant difference among the three feeding systems in rumen digesta particle distribution, the TMR group trended to have fewer large- and medium-sized particles and more small-sized particles than those in the SI1 and SI2 groups. In conclusion, cattle with dietary TMR showed increased weight gain and ruminal development and decreased BUN. This indicated that TMR feeding was more conducive toward improving the production performance and rumen fermentation of beef cattle.
Park Moon-Kyung;Cho Sun-Kyung;Cha Jin-A;Yang Il-Sun
Journal of Nutrition and Health
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v.39
no.4
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pp.417-425
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2006
The purpose of this study were to a) investigate operation of human resource in contract foodservice management company (CFMC), b) identify the staffing indices for the establishment an labor productivity for CFMC, and c) develop standardized model of staffing demand as foodservice's scale in CFMC. The data was collected using FS intra-net system from 138 contract-managed foodservice operations in A CFMC and statistical analysis was completed using the SAS/win package (ver. 8.0) for description analysis, ANOVA, Duncan multiple comparison, pearson correlation analysis, and regression analysis. The types of operation were included factory (45%), small scale operation (26%), office (11%), department store (10%), training institute (4%), and hospital (3%). The distribution of foodservice scale was classified by meal served was as follows; 'less than 500 meals (47%)', 'from 500 to 1500 meals (25%)', 'from 1500 to 2500 meals (17%)', and 'more than 2500 meals (12%)'. There was two types of contract method, fee-contract (53%) and profit-and-loss contract (46%) Some variables were significantly high operation indices such as selling price, food cost, monthly sales, net profit and others were significantly low operation indices such as labor, meal time a day in the small foodservice on meal scale (p<.001). The more foodservice was large, the more human resource was disposed on dietitian, cook, cooking employee altogether (p<.001). Foodservice in A CFMC was divided into 2 groups by 500 meals a day, according to comparative analysis of labor productivity as meal scale per working hour, meal scale a day and operation indices as meal per foodservice employee, meal per cooking employee (p<.001). The regression equation model was developed as 'the number of employees=1.82+0.014 ${\times}$ meal served' in the operation of less than 500 meals, 'the number of employees=9.42+0.013 ${\times}$ meal scale a day -0.94 ${\times}$ meal scale per working hour' in the operation over 500 meal scale using labor productivity indices and operation indices. Therefore, CFMC could be enhanced efficiency of human resource arrangement using the standardized model of staffing demand and would be increased effectiveness of profit.
Narcolepsy is characterized by sleep attack with excessive daytime sleepiness(EDS), cataplexy, sleep paralysis, and hypnagogic hallucination. Paradoxically, narcoleptics tend to complain of frequent arousals and shallow sleep during the night time despite their excessive sleepiness. However, nocturnal sleep fragmentation in narcoleptics is relatively ignored in treatment strategies, compared with sleep attack/EDS and cataplexy. In our paper, we attempted to investigate further on the poor nocturnal sleep in narcoleptics and to discuss possible treatment interventions. Out of consecutively seen patients at Seoul National University Sleep Disorders Clinic and Division of Sleep Studies, we recruited 57 patients, clinically assessed as having sleep attack and/or EDS. Nocturnal polysomnography and multiple sleep latency test(MSLT) were done in each of the subjects. We selected 19 subjects finally diagnosed as narcolepsy(mean age $26.0{\pm}18.3$ years, 16 men and 3 women) for this study, depending on the nocturnal polysomnographic and MSLT findings as well as clinical history and symptomatology. Any subject co-morbid with other hypersomnic sleep disorders such as sleep apnea or periodic limb movements during sleep was excluded. Sleep staging was done using Rechtschaffen and Kales criteria. Sleep parameters were calculated using PSDENT program(Stanford Sleep Clinic, version 1.2) and were compared with the age-matched normal values provided in the program. In narcoleptics, compared with the normal controls, total wake time was found to be significantly increased with significantly decreased sleep efficiency(p<.01, p<.05, respectively), despite no difference of sleep period time and total sleep time between the two groups. Stage 2 sleep%(p<.05), slow wave sleep%(p<.05), and REM sleep%(p<.01) were found to be significantly decreased in narcoleptics compared with normal controls, accompanied by the significant increase of stage 1 sleep%(p<.01). Age showed negative correlation with slow wave sleep%(p<.05). The findings in the present study indicate significant fragmentation of nocturnal sleep in narcoleptics. Reduction of REM sleep% and the total number of REM sleep periods suggests the disturbance of nocturnal REM sleep distribution in narcoleptics. No significant correlations between nocturnal polysomnographic and MSLT variables in narcoleptics suggest that nocturnal sleep disturbance in narcoleptics may be dealt with, in itself, in diagnosing and managing narcolepsy. With the objective demonstration of qualitative and quantitative characteristics of nocturnal and daytime sleep in narcoleptics, we suggest that more attention be paid to the nocturnal sleep fragmentation in narcoleptics and that appropriate treatment interventions such as active drug therapy and/or circadian rhythm-oriented sleep hygiene education be applied as needed.
Journal of Korean Society of Environmental Engineers
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v.39
no.12
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pp.698-705
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2017
Environmental impact of a mobile phone charger containing recycled plastic was quantified using LCA and the environmental benefits from the use of recycled and virgin plastic were compared. The assessment considers potential environmental impacts across the whole life cycle of the charger including; pre-manufacturing; manufacturing; distribution; product use; and end-of-life stages and quantified six environmental impact categories; Abiotic depletion; Acidification; Eutrophication; Global warming; Ozone layer depletion; and Photochemical oxidants creation. The study showed that the environmental impacts of the use stage accounted for 94.4% and 70% in the resource depletion and global warming impact categories, respectively, and the environmental impacts of the pre - manufacturing stage accounted for more than 98% in the other impact categories. The main cause of the environmental impacts in the use stage was electricity consumed by the charger. The main cause in the pre-manufacturing stage was PBA (Printed Board Assembly) and external case manufacturing. In order to quantify the environmental benefits of recycled PC (Polycarbonate) in the exterior case, the environmental impacts of 1 kg production of recycled PC and virgin PC were evaluated. The environmental impact on the abiotic depletion of the recycled PC is estimated to be 30% compared to the virgin PC, and the impacts on the other impact categories of the recycled PC were less than 5% of the virgin plastic. Sensitivity analysis was performed for 12 items including site data and assumptions made. The sensitivity of each item was less than 10%. The results of this study confirm that designing compact and light PBA, improving charging efficiency, and use of recycled plastic are important design factors to reduce the environmental impact of a charger.
Journal of Korean Society of Environmental Engineers
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v.28
no.3
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pp.249-256
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2006
Catalytic combustion of toluene was investigated on the Cu-Mn oxide catalysts prepared by the impregnation(Imp) and the deposition-precipitation(DP) methods. The mixing of copper and manganese has been found to enhance the activity of catalysts. It is then found that catalytic efficiency of the Cu-Mn oxide catalyst prepared by the DP method on combustion of toluene is much higher than that of the Cu-Mn oxide catalyst prepared by Imp method with the same chemical composition. The catalyst prepared by the deposition-precipitation method observed no change of toluene conversion at time on stream during 10 days and at the addition of water vapor. On the basis of catalyst characterization data, it has been suggested that the catalysts prepared by the DP method showed uniform distribution and smaller particle size on the surface of catalyst and then enhanced reduction capability of catalysts. Therefore, we think that the DP method leads on progressive capacity of catalyst and promotes stability of catalyst. It was also presumed that catalytic conversion of toluene on the Cu-Mn oxide catalyst depends on redox reaction and $Cu_{1.5}Mn_{1.5}O_4$ spinel phase acts as the major active sites of catalyst.
Journal of the Korea Academia-Industrial cooperation Society
/
v.15
no.2
/
pp.1036-1043
/
2014
The installation of PV system to the power distribution system is being increased as one of solutions for environmental pollution and energy crisis. Because the output efficiency of PV system is getting decreased because of the aging phenomenon and several operation obstacles, the technology development of output prediction and state diagnosis of PV modules are required in order to improve operation performance of PV modules. The conventional methods for output prediction by considering various parameters and standard test condition values of PV modules may have difficult and complex computation procedure and also their prediction values may produce large error. To overcome these problems, this paper proposes an optimal prediction algorithm and state diagnosis algorithm of PV modules by using least square methods of linear regression analysis. In addition, this paper presents a state diagnosis evaluation system of PV modules based on the proposed optimal algorithms of PV modules. From the simulation results of proposed evaluation system, it is confirmed that the proposed algorithms is a practical tool for state diagnosis of PV modules.
Background: This study aimed to assess the appropriate allocation of emergency medical beds across 17 provinces and presume the economic benefits associated with such allocation. Methods: To estimate the optimal allocation of emergency medical beds by province, data from the Statistics Korea's "cause of death statistics (2014-2021)," regional statistics on "area, population, gender, age," and "population projections" were utilized. The "number of emergency beds by city and district" provided by the Health Insurance Review and Assessment Service was also used. In estimating the economic benefits of preventing avoidable emergency deaths due to the expansion of emergency medical facilities, guidelines from the Korea Development Institute and the Korea Transport Institute were referenced to calculate the wage loss costs associated with emergency deaths and estimate the economic benefits. Results: The optimal ratio of emergency medical beds allocation by region was highest in Gyeonggi, Seoul, Gyeongnam, Gyeongbuk, and Busan, while Daejeon, Jeju, and Sejong showed lower ratios. Additionally, the prevention of avoidable deaths and economic benefits resulting from the increase in emergency medical facilities were highest in Gyeonggi, Seoul, Gyeongbuk, Gyeongnam, and Busan. However, when standardized by population, the prevention of avoidable deaths and economic benefits were analyzed to be highest in Gyeongbuk, Chungnam, Jeonnam, Gyeongnam, and Busan. Conclusion: The results of this study can serve as foundational data for future policy measures aimed at addressing the imbalance in the supply of emergency medical facilities across regions. Considering regional characteristics in the distribution of emergency medical facilities is expected to ultimately increase the efficiency of national finances and yield economic benefits.
Jun-Myung Choi;Junhyuk Ha;Ranyeong Choi;Jun-Yeop Lee
Journal of Radiation Industry
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v.18
no.3
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pp.167-171
/
2024
Technetium-99 (99Tc) is recognized as a critical concern in the disposal of spent nuclear fuel due to its long half-life and remarkable stability, existing predominantly as TcO4- in the natural environment. The anionic form of technetium is highly soluble and mobile, posing significant environmental risks from the viewpoint of nuclear waste management. Thus, developing efficient and cost-effective sorbents for aqueous Tc(VII) is essential for mitigating relevant contamination. In the present work, the adsorption characteristics of Re(VII), a chemical analog of Tc(VII), were investigated using the clay mineral bentonite, modified with two different organic cations: hexadecylpyridinium (HDPy) and hexadecyltrimethylammonium (HDTMA). Sorption experiments were conducted at a liquid-to-solid ratio of 1 g/L with Re(VII) solutions prepared at concentrations from 10-4 mol/L to 10-6 mol/L. The sorption ratio and distribution coefficients were determined with samples collected at reaction times of 10, 50, 100, and 500 minutes after 0.45 ㎛ syringe filtration. In parallel, the modified bentonite samples were further analyzed using the X-ray diffraction (XRD) method to understand the adsorption mechanism of Re(VII) onto the target minerals. According to the quantification analysis results, a rapid equilibrium reaction of aqueous Re(VII) for all modified bentonite samples was identified. Moreover, near-complete adsorption of Re(VII) was observed when the bentonite was modified at 200-400% of its cation exchange capacity (CEC) for both organic cations. For cases of lower modification, the HDTMA-modified bentonite showed relatively higher adsorption efficiency compared with the one modified with HDPy. This result was inferred to be due to the difference in inter-layer spacing based on the characteristics of the organic cations. It is expected that the results obtained through this study will serve as a preliminary case for the synthesis of adsorbents for the retardation of highly mobile anionic radionuclides, such as I and Tc, in the natural environment.
This experimental study was intended to improve the compressive strength of multi-walled CNT reinforced cementitious composites with efficiency. The variables considered are the degree of sonication, the amount of surfactant, the replacement ratio of silica fume, etc. Optical microscope informed that fiber dispersion of CNT was improved with the increase of sonication time, and the compressive strength was proved to be enhanced as the degree of sonication increased. When superplasticizer as a surfactant had SP/CNT ratio of 4~6, the best improvement in strength was obtained. Silica fume was shown to produce the highest compressive strength at 10% replacement. Microstructure of CNT composites was also analyzed; XRD and SEM results indicated that CNT addition hardly changed hydration products and microstructure, and MIP analysis found the reduction of total porosity as well as the increase of nano-pores with the size of tens of nm instead of the decrease of pore distribution in the region of around 10 ${\mu}m$ and 100 nm. The results of microstructure analysis explains that the strength improvement is closely related to physical contribution rather than chemical influence by adding CNT.
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