Li, Jung Hua;Kweon, Hyun Kyu;Gwon, Dong Jae;Park, Sang Jun;Jeon, Yoo Jin
Journal of the Semiconductor & Display Technology
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v.21
no.1
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pp.27-32
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2022
There has always been a demand for orthodontic treatment. Orthodontic treatment allows tooth to be arranged by flexible arch wire fixed with tooth-attached brackets. Arch wire generate constant pressure to tooth brackets which moves the teeth to proper place. When the bracket transmits force, the braced wing of the bracket may deform. Deformed tie wing will lead to lost tension of elastic ligature. Then, lacking grip between tie wing and ligature might delay the tooth movement. Furthermore, tooth brackets used for orthodontic treatment make contact with in direct oral surface and this cause feeling of irritation that comes from height of tooth braces. This study suggests an optimal teethe bracket design to make up for inconvenience by shorten the height of bracket and complement the shape of bracket to reduce strain rate using finite element analysis. As a result, new optimal design of teethe bracket indicates lower strain rate of the bracket wing and takes good effects of shorten body height in terms of convenience.
Aerodynamic effects, such as drag force and flow-induced vibration (FIV), on civil engineering structures can be minimized by optimally modifying the structure shape. This work investigates the turbulent wake of a square prism with its faces modified into a sinusoidal wave along the spanwise direction using three-dimensional large eddy simulation (LES) and particle image velocimetry (PIV) techniques at Reynolds number $Re_{Dm}$ = 16,500-22,000, based on the nominal width ($D_m$) of the prism and free-stream velocity ($U_{\infty}$). Two arrangements are considered: (i) the top and bottom faces of the prism are shaped into the sinusoidal waves (termed as WSP-A), and (ii) the front and rear faces are modified into the sinusoidal waves (WSP-B). The sinusoidal waves have a wavelength of $6D_m$ and an amplitude of $0.15D_m$. It has been found that the wavy faces lead to more three-dimensional free shear layers in the near wake than the flat faces (smooth square prism). As a result, the roll-up of shear layers is postponed. Furthermore, the near-wake vortical structures exhibit dominant periodic variations along the spanwise direction; the minimum (i.e., saddle) and maximum (i.e., node) cross-sections of the modified prisms have narrow and wide wakes, respectively. The wake recirculation bubble of the modified prism is wider and longer, compared with its smooth counterpart, thus resulting in a significant drag reduction and fluctuating lift suppression (up to 8.7% and 78.2%, respectively, for the case of WSP-A). Multiple dominant frequencies of vortex shedding, which are distinct from that of the smooth prism, are detected in the near wake of the wavy prisms. The present study may shed light on the understanding of the underlying physical mechanisms of FIV control, in terms of passive modification of the bluff-body shape.
International Journal of Computer Science & Network Security
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v.24
no.8
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pp.191-204
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2024
IOT has carried out important function in converting the traditional fitness care corporation. With developing call for in population, traditional healthcare structures have reached their outmost functionality in presenting sufficient and as plenty as mark offerings. The worldwide is handling devastating developing antique population disaster and the right want for assisted-dwelling environments is turning into inevitable for senior citizens. There furthermore a determination by means of the use of way of countrywide healthcare organizations to increase crucial manual for individualized, right blanketed care to prevent and manipulate excessive coronial situations. Many tech orientated packages related to Health Monitoring have been delivered these days as taking advantage of net boom everywhere on globe, manner to improvements in cellular and in IOT generation. Such as optimized indoor networks insurance, community shape, and fairly-low device fee performances, advanced tool reliability, low device energy consumption, and hundreds higher unusual common usual performance in network safety and privacy. Studies have highlighted fantastic advantages of integrating IOT with health care location and as era is improving the rate also cannot be that terrific of a problem. However, many challenges in this new paradigm shift notwithstanding the fact that exist, that need to be addressed. So the out most purpose of this research paper is 3 essential departments: First, evaluation of key elements that drove the adoption and boom of the Internet of factors based totally domestic some distance off monitoring; Second, present fashionable improvement of IOT in home a long manner off monitoring shape and key building gadgets; Third, communicate future very last effects and distinct guidelines of such type a long way off monitoring packages going ahead. Such Research is a wonderful manner in advance now not outstanding in IOT Terminology but in standard fitness care location.
The purpose of this study is to present basic data that can express beautiful silhouette by studying visual effect that depend on waist position of basic pants and the change of round belt width and analyzing the study of visual effect of the pattern design as well as the effect of design component. The stimuli are 21 samples: 7 variations of the location of the waistline and 3 variations of the width of the belt. The data has been obtained from 35 fashion design majors. The data has analyzed by frequency, factor analysis, anova, scheffe's test and the MCA method. The visual effects by the location of waistline and the width of belt are composed of 3 factors : horizontal direction factor, vertical direction factor and flexuosity factor. In these factors, horizontal factor is estimated by most important factor. Visual effect is positive when belt width widens as the location of waist line goes down to position of low belt. And in case the location of waist line is in the position of natural waist belt and low rise belt, belt of 3.2cm width is effective visually. The interaction effects between the location of the waistline and the width of the belt have significant differences in all factors. Factor that appears in visual effect of basic pants can be evaluated differently according to pattern of pants and characteristic of body shape. So we may receive better visual assessment if we consider the location of waist belt and width of belt in side of visual effect and image, when we produce pants giving variety to crotch depth.
Yadav, Deepak;Anwar, Mohammad Faiyaz;Garg, Veena;Kardam, Hemant;Beg, Mohd Nadeem;Suri, Suruchi;Gaur, Sikha;Asif, Mohd
Asian Pacific Journal of Cancer Prevention
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v.15
no.5
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pp.2335-2340
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2014
Paclitaxel is hydrophobic in nature and is recognized as a highly toxic anticancer drug, showing adverse effects in normal body sites. In this study, we developed a polymeric nano drug carrier for safe delivery of the paclitaxel to the cancer that releases the drug in a sustained manner and reduces side effects. N-isopropylacrylamide/vinyl pyrrolidone (NIPAAm/VP) nanoparticles were synthesized by radical polymerization. Physicochemical characterization of the polymeric nanoparticles was conducted using dynamic light scattering, transmission electron microscopy, scanning electron microscopy and nuclear magnetic resonance, which confirmedpolymerization of formulated nanoparticles. Drug release was assessed using a spectrophotometer and cell viability assays were carried out on the MCF-7 breast cancer and B16F0 skin cancer cell lines. NIPAAm/VP nanoparticles demonstrated a size distribution in the 65-108 nm range and surface charge measured -15.4 mV. SEM showed the nanoparticles to be spherical in shape with a slow drug release of ~70% in PBS at $38^{\circ}C$ over 96 h. Drug loaded nanoparticles were associated with increased viability of MCF-7 and B16F0 cells in comparison to free paclitaxel. Nano loaded paclitaxel shows high therapeutic efficiency by sustained release action for the longer period of time, i increasing its efficacy and biocompatibility for human cancer therapy. Therefore, paclitaxel loaded (NIPAAm/VP) nanoparticles may provide opportunities to expand delivery of the drug for clinical selection.
The present study was carried out to investigate morphologic changes in the corpus luteum of the pregnant rat by electron microscope after administration of prostaglandin F2$\alpha$(PGF2$\alpha$). Pregnant rates were treated with PGF2$\alpha$(1,500$\mu\textrm{g}$/rat) and their corpura lutea were observed morphologically. The results obtained in this study were summarized as follows ; 1. The weight of the ovaries and corpura lutea were decreased slightly at 8~24 hours after PGF2$\alpha$ administratin but no significant differences were observed. 2. The number of corpora lutea and luteal cells decreased slightly at 12~48 hours and 18~24 hours after PGF2$\alpha$ tretment but there were no signifciant differences between control and treatment. 3. The weight of uterus and the unmber of embryo decreased slightly at 96 hours and at 18~96 hours after PGF2$\alpha$ administration but no significant differences were obtained. 4. In the electron microscopic observatons, lipid droplets which are electron dense and appear in the cytoplasm moderately increased in number after PGF2$\alpha$ treatment. The lipid droplets were surrounded by mitochodria and appeared in the autophagic vacuoles. 5. Moderated and high electron dense mitochondria which are round or elongated in shape showed pleomorphism from 3 hours after PGF2$\alpha$ treatment. Destruction of tubular of vesicular cristae was observed at 6 hours after the treatment. Dense body and myelin figures in matrix of mitochondria were also appeared. 6. Well-developed smooth endoplasmic reticulum(sER) showed tubular or vesicular cisternae. A number of whorl membranes containing ribosomes, mitochondria and lipid droplets were observed at 1.5 hour after treatment. sER was abundant in luteal cells at 12 hours were treatment. 7. Well-developed Golgi pparatus appeared obviously 6 hours and more prominently at 12 hours. Those Golgi vesicles were remarkably dilated. 8. Generally, a few rough endoplasmic reticulum (rER) were appeared after treatment and cisternae showed slight dilatation. No differences among the treatments were observed. However, slight dilation of cisternae was observed at 1.5 hours after treatment. 9. Ribosomes composed of free and polyribosomes were abundant before treatment but polyribosomes were appeared at 12 to 24 hours after treatment. 10. Intercellular space were slightly extended at 3 hours and markedly extended at 12 hours. Numerous microvillous protrusions were observed at these times. Membranous multivesicular structures and autophagic vacuoles were also appeared in the intercellular space. 11. At 3 hours after the treatment, autophagic vacuoles appeared in the cytoplasm of the cell. They increased in number with time and were observed to transfer to the intercellular space. Lysosomal dense body appeared in the cytoplasm and the inclusion body was also observed in nucleus at 12 to 24 hours after treatment.
Park, Young-Sun;Jang, Jae-Hee;Bae, Bok-Sun;Seo, Jung-Sook
Nutritional Sciences
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v.3
no.1
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pp.3-10
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2000
The present study was aimed at investigating the nutritional and physiological significance of rice bran as a source of dietary fiber as compared to pectin and wheat bran. The parameters for comparison included hypertrophy and morphology of intestines, stool weights and villus marker enzyme activity. For 6 weeks, 10 Sprague Dawley male rats were given one of six experimental diets: 1% cellulose control (CC), 5% pectin (P5), 5% rice bran(RB5), 10% rice bran(RB10), 5% wheat bran (WB5) or 10% wheat bran (WB10) based on the level of dietary fiber. Among experimental groups, food efficiency ratio and body weight gain was comparable. RB10 increased cecal and colonic tissue weights and content weights of cecum and colon as much as P5 did. Stool weight was positiviely correlated with colonic tissue weight (r=0.727, P<0.001), with colonic content weight(r=0.647, P<0.001). Small intestine length increased most in the P5 group, followed by the RB10 group. The scanning electron micrograph of jejunal villi from rice bran groups showed a leaf-shaped, smooth and regular pattern, whereas that of CC group produced a rather long shape. The wheat bran groups showed an irregular leafshaped pattern, and the pectin group typically produced leaf-shaped villi with surface damage. The activities of villus marker enzymes (maltase and sucrase) were higher in the bran-fed rats than in the control or pectin-fed rats. The results indicate than not only dietary fiber amounts but also fiber sources are closely related to the physiology and morphology of the large and small intestines in rats. Rice bran exerted effects on fecal output and trophic effects on the intestines similar to those of pectin.
Korean Journal of Computational Design and Engineering
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v.17
no.3
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pp.149-155
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2012
The ankle over-pronation causes the mechanical overloading transferred to proximal areas (i.e. knees or hips) over time. Thus, the over-pronation is recognized as a contributory factor in a wide variety of musculo-skeletal pathologies in lower extremities. Commonly, over-pronated ankles are treated using specially designed insoles that support medial heels and correct the posture of lower limbs. However, the biomechanical effects of the insoles are not yet fully understood, so there still are controversies whether such insoles really have clinical significance. In this study, in order to verify the effects of insoles and determine the best shape of the insoles, we examined how the medio-lateral knee joint reaction force changes due to insole conditions through a case study about a subject. As a result, it is revealed that the medial heel post, which drastically reduced the peak medio-lateral knee joint reaction force, has significant effects on the gait of the over-pronated patients. However, in case that the arch support is combined together, the positive effect of the medial heel post may rather decrease.
There is a growing interest in breast augmentation surgery, which can most effectively maximize femininity, among modern women around the world. However, breast augmentation surgery is considered one of the most terrifying surgeries many women are afraid of, as many cases of its side effects have been reported. As a way to provide a complementary method to deal with it, this study investigated the effects of a non-surgical breast enhancement program by stretching soft tissue of the breast. According to the results, there was no change in body weight and breast elasticity, but there were marked increases in breast cup size, breast diameter and volume of the women who used this program. The external soft tissue expansion system was found to be effective in Korean women's change of breast shape. On the other hand, users should use this system regularly for some period of time, and this would limit their social activities. Therefore, for the effective use of this system, its users should make individual efforts.
Generally, global performance analysis in offshore platforms is performed using potential-based numerical tools, which neglect hydrodynamic viscous effects. In comparison with the potential theory, computational fluid dynamics (CFD) methods can take into account the viscous effects by solving the Navier-Stokes equation using the finite-volume method. The open-source field operation and manipulation (OpenFOAM) C++ libraries are employed for a finite volume method (FVM) numerical analysis. In this study, in order to apply CFD to the global performance analysis of a hull-mooring coupled system, we developed a numerical wave basin to analyze the global performance problem of a floating body with a catenary mooring system under regular wave conditions. The mooring system was modeled using a catenary equation and solved in a quasi-static condition, which excluded the dynamics of the mooring lines such as the inertia and drag effects. To demonstrate the capability of the numerical basin, the global performance of a barge with four mooring lines was simulated under regular wave conditions. The simulation results were compared to the analysis results from a commercial mooring analysis program, Orcaflex. The comparison included the motion of the barge, catenary shape, and tension in the mooring lines. The study found good agreement between the results from the developed CFD-based numerical calculation and commercial software.
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