• Archives of Plastic Surgery
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• 제33권3호
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• pp.347-352
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• 2006

Ingrowing toenail has been treated conventionally by various surgical treatment modlities. However, none of these procedures are perfect to achieve esthetic results with low cost, recurrence, and complication rates. Although mild cases can be treated conservatively, in severe recurrent cases, surgical treatment is preferred. The purpose of this study is to evaluate the effectiveness and safety of using partial matricectomy and paronychial advancement flap for correction of recurrent ingrowing toenail. Eight patients suffering from recurrent ingrowing toenail were operated using partial matricectomy and paronychial advancement flap in our department from August 2004 to August 2005. The number of recurrent episodes ranged from 2 to 5. With digital nerve block, the excision area was marked on nailplate and inflammed lateral nail fold. The horizontally designed paronychial flap considering defect size was effective for wide exposure of the neighboring germinal matrix, which is later to be completely excised or cauterized because remnant germinal matrix made postoperative spicule formation. The nailplate on the affected side was removed about 3-5 mm width longitudinally, being cautious not to damage the proximal dorsal nail fold. The same width of the sterile matrix including germinal matrix was excised longitudinally with inflammed granulation tissue and partial lateral nail fold on the affected side. The subcutaneously elevated paronychial flap was advanced to cover the defect and was anatomically sutured with 5-0 nylon sutures. We evaluated our procedure's effectiveness by examining some factors such as cosmetic results, recurrence, spicule formation, postoperative pain and duration of return to normal activities. In eight patients, no complication was observed such as recurrence, severe pain and spicule formation except for 1 case of infection. Postoperative discomfort was minimal. Average duration of return to normal activities was 12 days. Cosmetically the results were acceptable in all patients. The partial matricectomy and paronychial advancement flap for correction of recurrent ingrowing toenail were found to be technically simple, efficient procedure with a relative low recurrence rate and better cosmetic results.

• 기술혁신연구
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• 제21권1호
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• pp.141-163
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• 2013

국가성장동력으로서 생명공학의 중요성이 날로 높아짐에 따라 세계 각국은 생명공학분야의 기술경쟁력 확보에 몰두하고 있다. 치열한 글로벌 경쟁 속에서 효과적인 연구개발을 수행하기 위해서는 주변국들과 우리나라의 기술경쟁력을 파악하는 것은 매우 중요하다. 기술경쟁력을 분석하기 위해 주로 델파이와 같은 전문가 의견조사가 이루어지고 있지만 이같이 전문가 직관에 의존하는 방법은 주관적 성향이 강해 설문응답자에 따라 다른 결과가 나올 수 있다. 본 연구에서는 객관적 데이터를 바탕으로 한 기술경쟁력 분석을 위해 미국에 등록된 특허를 활용하였다. 대상국가로는 동북아의 중심국인 한국, 중국, 일본을 선택하였고, 분석 지표로서 특허수, 인용도지수, 영향력지수, 기술자립도, 기술력지수, 시장확보지수 등을 분석하였다. 뿐만 아니라 특허의 IPC 코드를 44개의 산업과 매칭시킴으로써 생명공학기술과 산업의 연계성을 분석하였고, 이를 바탕으로 기술의 융합도와 활용도를 수치화하였다. 해당 연구결과는 우리나라 생명공학분야 기술경쟁력 제고를 위한 정책 수립 시 기초자료로써 활용 할 수 있을 것이다.

• 천문학회보
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• 제42권1호
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• pp.30.2-31
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• 2017

Compact elliptical (cE) galaxies are in a rare class of stellar systems characterized by high stellar densities, small sizes, high velocity dispersion, and high metallicity corresponding to elliptical galaxies. cE galaxies have been observed around massive galaxies, so they could be formed under strong influences of tidal stripping and truncation. However, the recent discovery of isolated cE galaxies requires the need of new formation scenarios. We aim at finding cE galaxies in various environments using SDSS DR12, and studying stellar population of cEs as function of environments. Based on the typical properties of cE galaxies, we selected cE candidates by restricting that low-luminosity Mg > 19.5 mag, small sizes Re < 700 pc, and high velocity dispersions ${\sigma}$ > $60kms^{-1}$. Since effect radii of cE candidates are mostly smaller than the seeing size of SDSS photometry, we calculated the effective radius by fitting a Sersic profile. In addition, we assumed that host galaxies have brightness with Mr < -21 mag, and an environmental parameter is computed as distances between cE galaxies and host-galaxies. We found 112 cE galaxies at z < 0.05, which have high sersic indices (mean value is 5.2) similar to the typical massive elliptical galaxies. Mgb values of cE galaxies increase as the distances from the host galaxies decrease. Especially, for cEs close to the host galaxies (NcE; $D_{host}$ < 300 pc), the Mgb values are similar to those of massive elliptical galaxies, which is consistent with the previous studies. On the other hand, cE galaxies distant from the host galaxies (DcE; Dhost >300 pc) have lower Mgb values than the conventional cE. The Mgb values follow the ${\sigma}$-Mgb relation of elliptical galaxies, and are connected to its faint end. This can be explained as a result of different merger histories for differing environments. For example, NcE galaxies are formed by tidal stripping by massive galaxies as suggested by previous studies, but DcE galaxies could be linked with high-redshift spheroids (e.g. red nuggets) which have not evolved into present-day elliptical galaxies because of the environmental influences.

• 지역사회간호학회지
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• 제4권1호
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• pp.5-13
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• 1993

The objective of this study was to analyze the status of health examination, and the health care management of industries in Seoul. This will provide effective industrial health care services. 46 industries were selected as a sample, and were given self administered questionnaire developed by the academic affairs of community health nursing. The results of this study are as follows: (1) The general characteristics of industries: The greater part of the industries were manu facturing companies, 300-900 workers, in a one shift system. (2) The general characteristics of health man ager: 96% of the companies had industrial nurses and the larger industries had comprehensive health managers. 90% of the industrial nurses were full-time employees and 77% of the industrial physician were part time employees. 80% of the industrial physician were age 50 or older, while 59% of the industrial nurses were 25-29 years of age. (3) Health examination and follow up care: The proportions of the workers who took general health examination was 94%. Of those, 12% took secondary examinations. In secondary examinations, 36% were evaluated at the C-grade, 20% were evaluated at the D-grade. The proportion of the workers who were required to take special examination were 29% and of that, the proportion of the workers who actually took the examination was 88%. 85% of the workers who were recommended for follow up cares were given follow up care while working. The physical agents among the special examination were done the most frequently to detect the examination effects. (4) Health care services: Industrial nurses performed health examination most frequently and health education was done the least. There were significant differences in health care services according to the size of the industries. Companies with 300 workers or less had higher health care services than other groups. The three primary reasons of health care management and examinations of workers are: First, industrial nurses are requires to accumulate professional knowledge and experience through continuos' activities. Second, systematic and concert examination for industrial workers should be performed periodically. Third, it needs developing health education strategies that are important workers for health promotion in industries.

• 수면정신생리
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• 제2권1호
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• pp.55-64
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• 1995

수면중에는 여러 가지 호흡생리의 변화가 나타나는데, 호흡의 수의적 조절은 경미하고 대부분 대사성조절에 의해 호흡이 유지되며, 탄산가스와 산소변화에 의한 화학자극 및 호흡기계통의 기계적 자극에 대한 환기반응이 감소하고, 늑간근 및 상기도근육들과 같은 보조호홉근의 기능이 억제되며, 체위변동 즉 누운 자세에서는 여러 가지 호흡기능의 변화가 온다. 이러한 호흡생리의 변화로 정상인에서도 수면 중에는 경미한 환기장애(저환기)를 보일 수 있으며, 수면 무호흡이 있는 경우에는 환기장애가 더욱 현저하다. 환기장애 즉 만성 폐포저환기를 동반하는 질환은 심폐질환 이외에도 여러 가지가 있으며 수면 무호흡 증후군은 환기장애를 일으키는 중요한 원인중의 하나이다. 만성 폐포저환기를 보이는 환자는 원인질환에 관계없이 수면중에 환기장애가 더욱 심해지며 특히 수면 무호흡이 빈번하게 동반되는 경우에는 중증의 임상경과를 보인다. 폐쇄성 수면 무호흡증후군 환자는 수면중에 반복되는 저산소증과 각성반응으로 수면장애증상 이외에도 전신 고혈압과 심부정맥이 흔히 동반되며, 주간에도 저산소증을 보이는 심폐질환자에서 수변 무호흡증후군이 동반되는 경우 폐동맥고혈압과 폐성심이 올 수 있다. 이러한 심폐혈관계 합병증은 수면 무호흡증후군 환자의 장기사망율을 높이는 중요한 원인이 되며, 중증 환자의 경우 수면중에 급사할 수도 있다. 폐쇄성 수면 무호흡증후군 환자의 심폐혈관계 합병증과 장기사망율을 감소시키기 위해서는 적절한 치료법이 요구되며, 환기장애(만성 폐포저환기)의 다른 원인질환이 함께 있는 경우에는 수면 무호흡의 치료와 병행하여 이들 질환의 치료를 동시에 실시하여야 한다.

• Journal of Gastric Cancer
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• 제18권1호
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• pp.37-47
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• 2018

Purpose: The endoscopic management of a fully covered self-expandable metal stent (SEMS) has been suggested for the primary treatment of patients with anastomotic leaks after total gastrectomy. Embedded stents due to tissue ingrowth and migration are the main obstacles in endoscopic stent management. Materials and Methods: The effectiveness and safety of endoscopic management were evaluated for anastomotic leaks when using a benign fully covered SEMS with an anchoring thread and thick silicone covering the membrane to prevent stent embedding and migration. We retrospectively reviewed the data of 14 consecutive patients with gastric cancer and anastomotic leaks after total gastrectomy treated from January 2009 to December 2016. Results: The technical success rate of endoscopic stent replacement was 100%, and the rate of complete leaks closure was 85.7% (n=12). The mean size of leaks was 13.1 mm (range, 3-30 mm). The time interval from operation to stent replacement was 10.7 days (range, 3-35 days) and the interval from stent replacement to extraction was 32.3 days (range, 18-49 days). The complication rate was 14.1%, and included a single jejunal ulcer and delayed stricture at the site of leakage. No embedded stent or migration occurred. Two patients died due to progression of pneumonia and septic shock 2 weeks after stent replacement. Conclusions: A benign fully covered SEMS with an anchoring thread and thick membrane is an effective and safe stent in patients with anastomotic leaks after total gastrectomy. The novelty of this stent is that it provides complete prevention of stent migration and embedding, compared with conventional fully covered SEMS.

• 한국터널지하공간학회 논문집
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• 제15권4호
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• pp.401-413
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• 2013

최근 연약지반 터널 현장에 활용되는 슬러리 쉴드 TBM은 굴진면으로 슬러리가 주입됨으로 그 안정성을 확보하는 공법이다. 하지만 간극이 과다하여 슬러리에 의한 폐색이 발생하지 않는 조립질 지반에서는 적용이 어렵기 때문에 첨가제를 혼입하여 사용하기도 한다. 본 연구에서는 첨가제의 역할로서 탄산가스를 주입함으로 슬러리가 주입되었을 때에 간극 내에 탄산가스가 흡착하여 폐색현상을 촉진시키는 효과를 규명하였다. 실내실험 결과 탄산 혼입에 따라 슬러리 쉴드 터널이 적용 가능한 유효입경이 1.0 mm에서 2.6 mm가량으로 증가하였고, 필터계수 ${\lambda}$가 $0.007sec^{-1}$이상인 경우에 탄산에 의한 효과가 발생함을 알 수 있었다.

• Asian-Australasian Journal of Animal Sciences
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• 제25권11호
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• pp.1605-1610
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• 2012

Two experiments were conducted to study the effects of red pepper (Capsicum frutescens) powder or red pepper pigment on the performance and egg yolk color of laying hens. In Exp. 1, 210, thirty-wk old, Hy-line Brown laying hens were fed one of seven diets containing 0.3, 0.6, 1.2, 2.0, 4.8 or 9.6 ppm red pepper pigment or 0.3 ppm carophyll red. Each diet was fed to three replicate batteries of hens with each battery consisting of a row of five cages of hens with two hens per cage (n = 3). In Exp. 2, 180, thirty-wk old, Hyline Brown laying hens, housed similarly to those in Exp. 1, were fed an unsupplemented basal diet as well as treatments in which the basal diet was supplemented with 0.8% red pepper powder processed in a laboratory blender to an average particle size of $300{\mu}m$, 0.8% red pepper powder processed as a super fine powder with a vibrational mill ($44{\mu}m$) and finally 0.8% red pepper powder processed as a super fine powder with a vibrational mill but mixed with 5% $Na_2CO_3$ either before or after grinding. A diet supplemented with 0.3 ppm carophyll red pigment was also included (n = 3). In both experiments, hens were fed the red pepper powder or pigment for 14 days. After feeding of the powder or pigment was terminated, all hens were fed the basal diet for eight more days to determine if the dietary treatments had any residual effects. In Exp. 1, there were no differences in egg-laying performance, feed consumption or feed conversion ratio due to inclusion of red pepper pigment in the diet. Average egg weight was higher (p<0.05) for birds fed 1.2, 2.4 or 9.6 ppm red pepper pigment than for birds fed the diet containing 0.3 ppm red pepper pigment. On d 14, egg color scores increased linearly as the level of red pepper pigment in the diet increased. In Exp. 2, feeding red pepper powder did not affect egg-laying performance, feed consumption or feed conversion ratio (p>0.05). However, compared with the control group, supplementation with all of the red pepper powder treatments increased egg weight (p<0.05). All the red pepper powder treatments also increased (p<0.05) the yolk color score compared with the control. The results of the present study suggest that both red pepper powder and pigment are effective feed additives for improving egg yolk color for laying hens.

• Asian-Australasian Journal of Animal Sciences
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• 제26권6호
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• pp.755-765
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• 2013

The accumulation of inbreeding and the loss of genetic diversity is a potential problem in the modern swine breeds in China. Therefore, the purpose of this study was to analyze the pedigrees of Chinese Duroc (CD), Landrace (CL) and Yorkshire (CY) swine to estimate the past and current rates of inbreeding, and to identify the main causes of genetic diversity loss. Pedigree files from CD, CL and CY containing, 4529, 16,776 and 22,600 records, respectively, were analyzed. Pedigree completeness indexes of the three breeds, accounting for one generation back, were 83.72, 93.93 and 93.59%, respectively. The estimated average annual inbreeding rates for CD, CL and CY in recent three years were 0.21, 0.19 and 0.13%, respectively. The estimated average percentage of genetic diversity loss within each breed in recent three years was about 8.92, 2.19, and 3.36%, respectively. The average relative proportion of genetic diversity loss due to unequal contributions of founders in CD, CL and CY was 69.09, 57.95 and 60.57%, and due to random genetic drift was 30.91, 42.05 and 39.43%, respectively. The estimated current effective population size for CD, CL and CY was 76, 117 and 202, respectively. Therefore, CD has been found to have lost considerable genetic diversity, demanding priority for optimizing the selection and mating to control future coancestry and inbreeding. Unequal contribution of founders was a major cause of genetic diversity loss in Chinese swine breeds and random genetic drift also showed substantial impact on the loss of diversity.

• Asian-Australasian Journal of Animal Sciences
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• 제31권9호
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• pp.1442-1448
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• 2018

Objective: This study was conducted to evaluate the effect of different levels of total digestible nutrients (TDN) and sodium stearoyl-2-lactylate (SSL) supplementation on growth performance and blood and carcass characteristics in Hanwoo steers during the early fattening period. Methods: Sixty Hanwoo steers (average body weight, $333{\pm}36.4kg$) were randomly allotted to 3 treatments, with twenty steers per treatment, and ten steers per pen with a size of $80m^2$. Dietary treatments were as follows: CON, basal diet; treatment (TRT) 0.5, 0.5% down-spec of TDN with 0.1% SSL; TRT 1.0, 1.0% down-spec of TDN with 0.1% SSL. Results: The results demonstrated that average daily gain and feed efficiency increased with TRT 0.5 (0.85 kg and 11.68) vs CON (0.82 kg and 11.27) or TRT 1.0 (0.78 kg and 10.74), indicating that 0.1% SSL supplementation in the feed of early fattening steers may result in a saving of 0.5% TDN. No significant differences were observed amongst all treatments (p>0.05) for blood metabolite concentration and blood corpuscle values, which were all within the normally accepted range for healthy steers. Conclusion: Our study suggests that a TDN 0.5% down spec with 0.1% SSL supplemented feed may be effective and profitable for the early fattening period of Hanwoo steers without causing adverse effects.