• Proceedings of the Korean Environmental Health Society Conference
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• 2004.06a
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• pp.173-177
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• 2004

The acute toxicities of two major anti-pathogenic veterinary medicines, i.e., ciprofloxacin and enrofloxacin, and six benzimidazole anthelmintics, i.e., albendazole, thiabendazole, flubendazole, febantel, fenbendazole, and oxfendazole, were evaluated with a marine bacterium, Vibrio fischeri, and invertebrate Daphnia magna. These veterinary medical products have been widely used for farm animals, but their impact on aquatic fauna has seldom been investigated. In general, daphnids responded as much as 3 orders of magnitude more sensitively to the tested pharmaceuticals than the microbes. For Daphnia, the most toxic product among the tested anthelmintics was fenbendazole, followed by flubendazole > albendazole ${\approx}$ febantel > thiabendazole > oxfendazole. Daphnids' EC50 values obtained from 48 to 96 hrs of fenbendazole exposure ranged from 2.7 to 6.3 ug/L. The mixture toxicity of the test pharmaceuticals was generally additive in nature and was well predicted by a concentration addition model. Using the predicted no effect concentrations (PNECs) of the benzimidazole derivatives estimated from this study, and predicted environmental concentrations (PECs) of these pharmaceuticals, the risk quotients of each anthelmintics were calculated. Most of the test anthelmintic compounds resulted in risk quotients greater than 1. Especially, risk quotient for fenbendazole was 2,791, which strongly indicates this compound might cause severe ecological consequences, should no future action be taken. This study is the first report on the aquatic toxicities and potential ecological risk of major anthelmintic and antimicrobial veterinary products in Korea. The result of this study provides information necessary for conducting more detailed ecological risk assessment of pharmaceutical products in ambient water and guiding proper management decision.

• Journal of the Korean Society for Marine Environment & Energy
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• v.18 no.4
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• pp.245-253
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• 2015

Total acid digestion and 1 M HCl extraction methods were used to investigate the pollution status and the degree of ecological risk of trace metals in surface sediments from the Ulsan-Onsan coast. Total concentrations of trace metals (Cu, Cd, Pb, Zn, and Hg) were two-fold higher in surface sediments from Onsan coast than in those from Ulsan coast. The mean labile fractions of the total concentrations of Cd and Pb were 72% and 78%, respectively, indicating a high contribution from anthropogenic sources, whereas Cr, Li, Ni, and As in the residual fraction exceeded 80%, indicating a high contribution from natural sources. According to the results of assessment of trace metal pollution using the sediment quality guidelines in Korea, the concentrations of Cu, Pb, Zn, and Hg were higher than the values of the probable effects level (PEL) at some stations of Onsan coast, and the concentrations of Cr and Ni were lower than the values of the threshold effects level (TEL). The pollution level and ecological risk of the trace metals were analyzed using various indexes (EF, $I_{geo}$, m-PEL-Q, and ERI). Our results showed that the degree of pollution by trace metals (Cu, Cd, Pb, Zn, and Hg) on the Ulsan-Onsan coast was high, and Hg and Cd were the major potential ecological risk factors.

• The Journal of the Korea Contents Association
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• v.21 no.3
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• pp.720-729
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• 2021

The purpose of this study was to measure repeated the process of non-suicidal self-injury individuals change in everyday life through the Ecological Momentary Assessment(EMA) daily diary. The study subjects of were 17 adults aged 19 to 29, accessed a link sent by text message on a cell phone and recorded a diary of the day's affects, interpersonal conflicts, self-injury thoughts, and behaviors once a day for two weeks. Using a total of 238 reported entries, the contextual factors of NSSI were examined, and the effects of affects and interpersonal conflicts on NSSI analyzed through a multi-level model. As a result, the negative affects of that day have a significant relation with within subject NSSI behavior and positive affects have a significant relation between subject NSSI behavior. These findings means that overall individuals with low positive affects have a higher risk of self-injury behavior compared to those with higher levles of positive emotions, and an increase in negative emotions on that day within an individual increases the risk of self-injury behavior on that day. In other words, it implies that it is important to manage negative emotions and strengthen overall positive affects for that day in the intervention of emotion-regulation of experienced self-injury individuals. It is meaningful that this study explored NSSI risk factors experienced in daily life through the short-term longitudinal study.

• The Korean Journal of Pesticide Science
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• v.15 no.1
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• pp.48-54
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• 2011

Risk assessments of pesticides detected in six major rivers during peak season were estimated for algae, Daphnia, and fish using hazard quotient (HQ) indexes. The eight pesticides (isoprothiolane, hexaconazole, diazinon, chlorpyrifos, prothiofos, alachlor, butachlor, molinate) were detected within the range of 0.027~12.871 ${\mu}g/L$. Detection frequency of isoprothiolate was estimated to be high at 67.5%, and those of the others varied from 15.0 to 37.5%, Hazard Quotients (HQ) indexes varied by freshwater organisms (algae, Daphnia, and fish). Overall, the ecological risk probability due to exposure of pesticides detected in major rivers did not reveal based on HQ indexes below 1.0. Particularly, butachlor and molinate for algae, chlorpyrifos, diazinon, prothiofos for Daphnia, and chlorpyrifos for fish acted as dominant contributors in increasing the ecological risk in six major rivers. This implied that integrated ecological risk assessment is required using various biological species, reflecting toxicity sensitivity. This study may provide the essential data in establishing the priority for pesticides management in major rivers, Korea.

• Advances in environmental research
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• v.7 no.3
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• pp.177-200
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• 2018

Sixteen USEPA priority polycyclic aromatic hydrocarbons (PAHs) in the surface water from the coastal areas of Bangladesh were analyzed by GC-MS/MS. Samples were collected in winter and summer, 2015. The total concentration of PAHs (${\Sigma}PAHs$) showed a slight variation in the two seasons, which varied from 855.4 to 9653.7 ng/L in winter and 679.4 to 12639.3 ng/L in summer, respectively. The levels of ${\Sigma}PAHs$ were comparable to or relatively higher than other coastal areas around the world. The areas with recent urbanization and industrialization (Chittagong, Cox's Bazar and Sundarbans) were more contaminated with PAHs than the unindustrialized area (Meghna Estuary). Generally, 2-3-ring PAHs were the dominant compounds. Molecular ratios suggested that PAHs in the study areas could be originated from both pyrogenic and petrogenic sources. The risk assessment revealed the extremely high ecological risk of PAHs, indicating an intense attention should be paid to PAHs pollution in the coastal areas of Bangladesh.

• Korean Journal of Ecology and Environment
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• v.44 no.3
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• pp.272-279
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• 2011

Copper cyanide is a chemical produced in large quantities with 2,500 tonnes being produced in 2006. It is mainly used for electroplating copper, particularly alkali-Cu plate and brass plating. The purpose of this study is to reassess the physicochemical properties and environmental fate of copper cyanide based on reliable data and and to conduct an ecotoxicity test according to the OECD test guidelines as an initial environmental risk assessment (need to state where this was done). Metal containing inorganic substances are not subject to degradation, biodegradation or hydrolysis. Aquatic toxicity tests of copper cyanide were conducted according to OECD test guideline 201, 202 and 203 for green algae, daphnia, and fish, respectively. The following acute toxicity test results were obtained for aquatic species: 0.089 mg $L^{-1}$ (Algae, 72 Hr-$EC_{50}$); 0.21 mg $L^{-1}$ (flea, 48 Hr-$LC_{50}$); 0.62 mg $L^{-1}$ (Fish, 96 Hr-$ErC_{50}$). The chemical possesses properties indicating a hazard for the aquatic environment (acute toxicity in fish, daphnia and algae below 1.0 mg $L^{-1}$). As a result of this study, copper cyanide has become a candidate for detailed risk assessment. Countries that produce this chemical in significant quantities are recommended to perform specific assessments.

• Korean Journal of Environmental Biology
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• v.25 no.1
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• pp.1-7
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• 2007

Medaka(Oryzias latipes) and earthworm(Eisenia fetida) toxicity tests were carried out and ecological risk assessment in water and soil was performed with national monitoring data. NOEC of alachlor was $100\;{\mu}g\;L^{-1}$ in the medaka early life-stage test. Embryonic development, hatchability and time to hatching of medaka eggs were affected by this chemical. The $LC_{50}$ and NOEC of alachlor were $94.1\;mg\;kg^{-1}\;and\;55.0\;mg\;kg^{-1}$, respectively, in the earthworm acute toxicity test. The environmental monitoring has been carrying out by NIER since 1999. Exposure levels of alachlor in water and soil were $ND{\sim}0.54\;{\mu}g\;L^{-1}\;and\;ND{\sim}0.9\;{\mu}g\;kg^{-1}$, respectively, in national monitoring data which had been performed from 2000 to 2004. The measured water and soil exposure levels were applied to evaluate the environmental risk assessment. The PNEC of alachlor in water and in soil were determined as $1\;{\mu}g\;L^{-1}\;and\;55.0\;{\mu}g\;kg^{-1}$, respectively using the safety factors which were suggested in EU and OECD. The HQs (PEC/PNEC) were determined to be below 1 for both water and soil when the maximum exposure levels ($0.54\;{\mu}g\; L^{-1}$ in water and $0.9\;{\mu}g\;kg^{-1}$ in soil) were applied. Conclusively, our study indicated that there was not significant ecological risk of alachlor in water and soil of our monitoring sites.

• Korean Journal of Environmental Biology
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• v.36 no.1
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• pp.43-49
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• 2018

The toxic assessment of the PBDEs (BDE-47, BDE-209) has been comprehensively investigated by using the rates of survival and population growth in the marine rotifer, Brachionus plicatilis. Chiefly, the survival rate was determined after a measurement of 24 hours of exposure to the BDE-47 (2,2'4,4'-Tetrabromodiphenyl ether) and the BDE-209 (2,2',4,4'-Decabromodiphenyl ether) was performed. The BDE-47 reduced survival rate in dose-dependent manner and a significant reduction were noted to have occurred at a concentration of greater than $3.9mg\;L^{-1}$, but the BDE-209 had no effect which was subsequently observed in this study. The population growth rate (r) was determined after 72 hours of exposure to toxicants in the study. It was observed that the r value in the controls (absence PBDEs) was greater than 0.5, and that it decreased as the dose-dependent manner as recorded. The survival rate when exposed to BDE-47 and BDE-209, $EC_{50}$ value was $13mg\;L^{-1}$ and $>1,000mg\;L^{-1}$, and population growth rate was $3.67mg\;L^{-1}$ and $862.75mg\;L^{-1}$, respectively. Therefore, the BDE-47 is considered to be 76-235 times more harmful than the BDE-209 as noted. In this study, the ecotoxicological bioassay using a noted survival rate and population growth rate of B. plicatilis can be used as a baseline data for the continued establishment of the environmental quality standard of the incidences of the BDE-47 and BDE-209 in a marine environment.

• Korean Journal of Environmental Biology
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• v.34 no.4
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• pp.353-360
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• 2016

Effect of heavy metals(Cd, Cu, Zn) on the survival and population growth rates(PGR) of marine rotifer, Brachionus plicatilis were examined. B. plicatilis were exposed to Cd, Cu and Zn for 24 h to determine their survival and 72 h to determine their PGR. Survival rates in the control groups were greater than 90%. They were decreased with increasing concentrations of Cd, Cu and Zn. Survival rates were reduced in a concentration-dependent manner. Significant reduction in survival rates after exposure to Cd, Cu and Zn at concentration greater than 40.00, 0.13 and $10.00mg\;L^{-1}$, respectively. PGR in the control groups were greater than 0.50. They were decreased with increasing concentrations of heavy metals. PGR were reduced in a concentration-dependent manner. Significant reduction in PGR after exposure to Cd, Cu and Zn occurred at concentration greater than 12.5, 0.06 and $1.00mg\;L^{-1}$, respectively. The order of heavy metal toxicity based on PGR was Cu>Zn>Cd, with $EC_{50}$ (50% Effective Concentration) values of 0.12, 6.15 and $21.41mg\;L^{-1}$, respectively. The lowest-observed-effective-concentrations(LOEC) of PGR after exposure to Cd, Cu and Zn were 12.50, 0.06 and $1.00mg\;L^{-1}$, respectively. The No-observed-effective-concentrations(NOEC) of PGR after exposure to Cd, Cu and Zn were 6.25, 0.03 and $0.01mg\;L^{-1}$, respectively, in marine ecosystems have toxic effects on PGR of B. plicatilis. These results suggest that the PGR of B. plicatilis are useful tool to assess the effect of heavy metals on primary consumers in marine natural ecosystems.

• Korean Journal of Environmental Biology
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• v.38 no.2
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• pp.207-215
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• 2020

Toxic assessment of antifouling agents (diuron and irgarol) was conducted using the fertilization and the normal embryogenesis rates of the sea urchin, Mesocentrotus nudus. Bioassessment began with male and female reproductive cell induction. White or cream-colored male gametes(sperm) and yellow or orange-colored female gametes (eggs) were acquired and fully washed, separately. Then, the fertilization and normal embryogenesis rates were measured after 10 min and 48 h of exposure to the toxicants, respectively. The fertilization and embryo development rates were greater than 90% in the control, validating the suitability of both endpoints. The normal embryogenesis rates were significantly decreased with increasing concentrations of diuron and irgarol, but no changes in the fertilization rates were observed in concentrations ranging from 0 to 40 mg L^-1. The EC₅₀ values of diuron and irgarol for the normal embryogenesis rates were 20.07 mg L^-1 and 22.45 mg L^-1, respectively. The no observed effect concentrations (NOEC) were <1.25 mg L^-1 and the lowest observed effect concentrations (LOEC) were 1.25 mg L^-1 and 2.5 mg L^-1, respectively. From these results, concentrations of diuron and irgarol over 1.25 mg L^-1 and 2.5 mg L^-1, respectively, can be considered to have toxic effects on invertebrates, including M. nudus. The ecotoxicological bioassay in this study using the noted fertilization and normal embryogenesis rates of M. nudus can be used as baseline data for the continued establishment of environmental quality standards for the effects of antifouling agents(especially diuron and irgarol) in a marine environment.