• Childhood Kidney Diseases
• /
• v.21 no.2
• /
• pp.47-52
• /
• 2017

Purpose: Renal ultrasonography has been widely used in children with renal disease. However, the relationship of renal echogenicity with renal pathology and function in children is not well known. Method: Ultrasound examination was performed in 75 patients undergoing renal biopsy for suspected renal disease in Konkuk University Medical Center from August 2005 to November 2015. We compared renal echogenicity to pathologic findings and renal function. Renal echogenicity was scored as 0 to 2 by comparing adjacent liver echogenicity. Three histologic characteristics were evaluated: glomerular changes, interstitial infiltration or fibrosis, and tubular atrophy. These were graded as 0 to 3, according to increasing severity. Laboratory results included urine albumin excretion and estimated glomerular filtration rate (eGFR). Results: Among pathologic findings, renal echogenicity revealed a positive correlation with interstitial infiltration or fibrosis (r=0.259, P=0.025), and with tubular atrophy (r=0.268, P=0.02). Renal echogenicity and glomerular changes were not correlated. Renal echogenicity showed a positive correlation with microalbuminuria (r=0.283, P=0.014), but a negative correlation with eGFR (r=-0.352, P=0.002). Conclusion: Increased renal echogenicity suggested severe interstitial infiltration or fibrosis and tubular atrophy among the pathologic findings. Moreover, increased echogenicity is correlated with increased urine albumin excretion and decreased eGFR. Echogenicity on ultrasonography is useful for determining the status of renal pathology and function.

• Korean Journal of Radiology
• /
• v.21 no.11
• /
• pp.1248-1255
• /
• 2020

Objective: To analyze long-term follow-up sonographic findings of intrathyroidal thymus in children. Materials and Methods: Among 1259 patients with congenital hypothyroidism under 15 years of age who underwent thyroid ultrasonography (US), 41 patients were diagnosed with an intrathyroidal thymus based on US criteria, i.e., hypoechoic solid lesion with punctate and linear echogenicity. In 26 patients aged one to 14 years old, the last follow-up US was performed after 6 to 132 months and compared with the initial US. The lesion was considered to decrease in size if there was a change of more than 2 mm in any dimension. The margin change was divided into well-defined and indistinct, blurred. When the echogenicity changed to a hyperechoic from a characteristic thymic echogenicity pattern, the pattern was considered a hyperechogenic. The changes in size were compared with the changes in shape, margin, and echogenicity pattern. The changes in size, shape, margin, and echogenicity were analyzed the association with the age of last follow-up. Statistical analysis was conducted using the chi-squared test and logistic regression. Results: Fifteen (57.7%) cases were stable in size, and 11 (42.3%) decreased in size, including one that disappeared. Ten (38.5%) cases changed to indistinct margins from initially well-defined margins including one case of initially indistinct margin. Six (23.1%) changed to hyperechogenic, from initially characteristic thymic echogenicity patterns. When follow-up change was compared, decreases in size were significantly associated with lesion changes to indistinct margins (p = 0.004). The age at last follow-up was significantly associated with change to hyperechogenicity (odd ratio, 2.141; 95% confidence interval, 1.144-4.010, p = 0.017). Conclusion: On follow-up US, an intrathyroidal thymus may be decreased in size, with indistinct margins, or show changes to a hyperechoic mass. Decreases in size may be associated with changing to indistinct margins, and changes to hyperechogenicity may be associated with increasing age.

• Journal of the Korean Academy of Clinical Electrophysiology
• /
• v.4 no.1
• /
• pp.13-25
• /
• 2006

This study aims to suggest clinical basis of physical therapy of neuromuscular system complication in type diabetic patients through a variety II of analysis methods including echogenicity using ultrasound image and measurement of peripheral nerve function to their neuromuscular system and provide basic materials for preparing evaluation of physical therapy and intervention program. Subjects of this study were 75 type II diabetic patients between 40 and 80 years old and it obtained the following results through echogenisity and function of peripheral nerve. Incidence of neuropathy in type II diabetes was 55.8% in men and 53.1% in women, and total incidence of neuropathy was 54.7%. Echogenicity of patients with neuropathy was significantly increased compared to that of patients with neuropahty. It was also found that there were correlations between function of peripheral nerve and echogenicity of tibialis anterior and gastrocnemius muscle. In addition, it will be important for physical therapists to divide type II diabetic patients into neuropathy and myopathy and interpret and approach changes of neuro-muscular system from comprehensive side.

• Journal of Veterinary Clinics
• /
• v.18 no.1
• /
• pp.35-43
• /
• 2001

Present study was undertaken in order to document early renal ultrasonographic changes of gentamicin nephrotoxicosis and to show the value of renal ultrasonography as a contributory means of early diagnosis of acute renal failure in dogs. The experimental design was a randomized complete block design with six treatments in two blocks (gentamicin-treated & saline-treated). Acute renal failure was induced by toxic dosage of gentamicin (30 mg/kg) and saline solution sham equivalent in volume to that of the toxic dosage of gentamicin (1.5-3ml). Subjective visualization of increased renal cortex was visible as homogenous echoes that were hypoechoic relative to the surrounding tissues, whereas the renal medulla was anechoic to slightly hypoechoic. After treatment, the renal cortex was hyperechoic relative to the surrounding tissue. Increased renal cortex echogenicity was associated with significant nephrotoxicosis and was superior to serum creatinine elevation in nephrotoxicosis detection. Urine GGT was superior to other clinicopathological data utilized in the diagnosis of nephrotoxicosis. Based on the above results, increased renal cortex echogenicity seemed to be of use in detecting of acute renal failure.

• Journal of the Korean Academy of Clinical Electrophysiology
• /
• v.7 no.1
• /
• pp.11-15
• /
• 2009

Purpose : This study aims to comparison of ultrasonography on both sides of biceps brachii muscle of hemiplegic patient. Methods : The biceps brachii muscle of fifteen subjects (5 male, 10 female) with stroke were scanned with ultrasonography at the muscle belly at rest at elbow angles of 90 deg. The echogenicity (density, white area index; WAI, anatomic cross-sectional area; ACSA, volume) of ultrasonography was examined. Results : In the biceps brachii muscle, there were significant differences of density, WAI, ACSA, and volume between affected side and non-affected side. biceps brachii muscle, echogenicity (density, WAI) of the affected side was higher than non-affected side. biceps brachii muscle, echogenicity (ACSA, volume) of the non-affected side was higher than affected side. Conclusion : This study showed that change of skeletal muscle architecture properties occurred biceps brachii muscle of the affected side muscle of hemiplegic patient.

• Journal of Embryo Transfer
• /
• v.22 no.4
• /
• pp.229-234
• /
• 2007

This study was undertaken to determine the normal appearance of the postpartum uterine involution. Postpartum changes in uterine shape, architecture, echogenicity and diameter were monitored with ultrasonography in 8 Miniature Schnauzer dogs. Vaginal discharge was observed visually during the 3 weeks of postpartum. A large amount of viscous dark green discharge changed progressively to a small amount of transparent discharge. In the uterine shape, the transverse images were crescent or polygonal at the beginning, but became circular after 16 days. At postpartum day 24, the longitudinal images of placental and interplacental sites were similar to each other The echogenicity of uterine structure was clearly distinguishable among the hyperechoic serous membrane, hypochoic myometrium, hyperechoic endometrium, and anechoic uterine contents during the first week postpartum, but afterward the interluminal boundaries and echogenicity became obscure gradually. In addition, the anechoic substance of the endometrial cavity was not observed after postpartum day 28. In the uterine diameter, the diameter of placental sites decreased markedly from 24 mm at the first day postpartum to 13 mm at day 7, and the diameter of interplacental sites decreased from 15 mm at postpartum day 1 to 10 mm at day 7. At postpartum day 65, the uterus (6.4 mm) changed little and had a uniform homogenous echo, and thus it was confirmed that uterine involution was completed at that time in Miniature Schnauzer dogs.

• Childhood Kidney Diseases
• /
• v.2 no.1
• /
• pp.26-33
• /
• 1998

This retrospective study was designed to evaluate the prognostic value and histologic correlation of sonography in childhood nephrotic syndrome. Sixty-nine patients with proteinuria over 2g per day at the time of presentation who were treated at the Korea University Hospital were included in this review. They were 1 to 15 years old(mean age, 7.8 years) with 49 males and 20 females. In each patient an ultrasound examination was done using SPA 1000(Diasonics, C.A., U.S.A.) on admission. Tissue specimens were obtained from 46 patients. The paraffin-embedded specimens were reviewed with special reference to interstitial edema, interstitial fibrosis, tubular atrophy, global sclerosis or inflammatory cell infiltrates. Biopsy proven renal disease were minimal change disease(n=20), focal segmental glomerulosclerosis(n=7), membranous glomerulonephritis(n=2), membranoproliferative glomerulonephritis(n=1), $Henoch-Sch\"{o}nlein$ purpura nephritis(n=6), IgA nephropathy(n=5), poststreptococcal glomerulonephritis(n=2), systemic lupus erythematosus(n=1) and Alport syndrome(n=2). There was a significant relationship between increased cortical echogenicity and global sclerosis or tubular atrophy(P<0.05). But no significant relationship was found between increased cortical echogenicity and interstitial fibrosis, interstitial edema, or inflammatory cell infiltration. In biopsy-proven primary nephrotic syndrome(n=30), no significant relationship was found between the increased conical echogenicity and the interstitial edema, interstitial fibrosis, global sclerosis, tubular atrophy or inflammatory cell infiltration. But there was a significant relationship between increased cortical echogenicity and resistance to corticosteroid (P<0.05). These results suggest that increased cortical echogenicity may be due to tubular atrophy or global sclerosis in patients with proteinuria and may be an effective indicator of resistance to corticosteroid in primary nephrotic syndrome.(J Korean Soc of Pediatr Nephrol 2:26-33, 1998)

• Journal of the Korean Society of Radiology
• /
• v.84 no.3
• /
• pp.596-605
• /
• 2023

Purpose This study aimed to evaluate the US features of the parathyroid glands (PTGs) using surgical specimens of normal PTGs obtained during thyroid surgery. Materials and Methods This study included 34 normal PTGs from 17 consecutive patients who underwent thyroid surgery between December 2020 and March 2021. All normal PTGs were histologically confirmed by intraoperative frozen-section biopsy for autotransplantation. Surgically resected parathyroid specimens were scanned in sterile normal saline using high-resolution US prior to autotransplantation. The US features of echogenicity (hyperechogenicity or hypoechogenicity), echotexture (homogeneous or heterogeneous), size, and shape (ovoid or round) were retrospectively evaluated. The echogenicity of the three PTGs was compared with that of the thyroid parenchyma of the resected thyroid specimens in two patients. Results All PTGs showed hyperechogenicity similar to that of gauze soaked in normal saline. Homogeneous hyperechogenicity was observed in 32/34 (94.1%) patients, and the echogenicity of the three PTGs was hyperechoic compared with that of the thyroid parenchyma. The long diameter of the PTGs ranged from 5.1 mm to 9.8 mm (mean, 7.1 mm) and the shape of the PTGs was ovoid in 33/34 (97.1%) patients. Conclusion The echogenicity of normal PTG specimens was consistently hyperechoic, and the small ovoid homogeneously hyperechoic structure was a characteristic US feature of the PTGs.

• Journal of the Korean Academy of Clinical Electrophysiology
• /
• v.5 no.1
• /
• pp.1-10
• /
• 2007

This study aims to comparison of ultrasonography on both sides of the upper arm of hemiplegic patient. The biceps brachii and deltoid muscle of ten subjects(4 men, 6 women) with stroke were scanned with ultrasonography at the muscle belly at rest at elbow angles of 90 deg. The echogenicity(densit, white area index; WAI) and muscle thickness of ultrasonography was examined using real-time B-mode ultrasonography with 7.5 MHz linear-array prob. In the biceps brachii muscle, MHz there were significant differences of thickness, density, and WAI between affected side and non-affected side. In the deltoid muscle, there were significant differences of thickness, density, and WAI between affected side and non-affected side. Both of the muscles, thickness of the affected side was thin than non-affected side and echogenicity(density, WAI) of the affected side was higher than non-affected side. This study showed that change of skeletal muscle architecture properties occurred in the upper arm of the affected side muscle of hemiplegic patient.

• Journal of the Korean Academy of Clinical Electrophysiology
• /
• v.5 no.1
• /
• pp.11-20
• /
• 2007

The purpose of this study were to analysis on quality properties of lower extremity of patient with stroke by the existence of the independent walking. We recruited fourteen adults after stroke(7 male, 7 female; mean age, 64y) for our study. The subjects were divided into two groups; independent walking group(3 male, 3 female) and non-independent walking group(4 male, 4 female). We used in this study included a B-mode ultrasonography scanner with a 7.5 MHz linea probe. During the experiment, the subject was seated in the chair. The echogenicity(density, white area index; WAI) of the tibialis anterior and rectus femoris muscles were measured on both sides of the leg. In both of the density and WAI, the tibialis anterior muscle were significant differences between paratic side and non-paratic side, the independent walking and non-independent walking group. However, in both of the density and WAI of the rectus femoris muscle were only significant differences between paratic side and non-paratic side. This study showed that stroke and the independent walking have influenced on quality properties of lower leg. Especially, the independent walking has influenced on the tibialis anterior muscle.