• Parasites, Hosts and Diseases
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• 제49권3호
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• pp.277-279
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• 2011

Hydatid cysts commonly affect the liver and the lung. However, they rarely involve bones with vertebral column. We hereby report a case of a female patient with cystic echinococcosis of the hip bone and ilium. She presented with a long history of frequent recurrences highlighting the dismal prognosis at this rare site. Resection of the hydatid cyst from the sacroiliac region was done with allograft and autograft (rib graft) with lumbosacroiliac fixation. Follow-up of the patient at 6 months showed no detectable abnormality on radiology and the patient was doing well.

• Parasites, Hosts and Diseases
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• 제27권2호
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• pp.131-140
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• 1989

사람의 포충증과 유구낭미충증을 혈청학적으로 진단하는 데에는 교차반응이 상호 빈번히 일어나 임상상이나 기타 병력 등을 기초로 하여야 감별진단이 가능하다. 이 연구는 혈청학적 진단상 두가지 질환에서 교차반응을 일으키는 항원분획을 관찰하고 또 포충증과 유구낭미충증에 특이하게 반응하는 분획이 각 낭액중에 있는지를 관찰하기 위하여 실시하였다. 사우디·아라비아와 리비아에의 근무하고 귀국한 다음 발병한 포충증 환자 5예의 혈청과 유구낭미충증 환자 67예, 기타 간흡충증, 폐흡충증, 스파르가눔증, 무구조충감염자 89예 혈청을 포충과 유구낭미충 낭액을 항원으로 각각 효소면역측정법(ELISA)으로 특이항체가(IgG)를 측정하였다. 그 결과 포충 낭액에 대하여 포충증 혈청은 전례에서, 유구낭미충증 혈청은 49.3%에서, 기타 기생충증 혈청은 5.6%에서 양성반응을 보였다. 유구낭미충 낭액에 대하여 포충증 혈청은 전례가, 유구낭미충증 혈청은 55.1%가, 기타 기생충증 혈청은 12.3%가 양성반응을 나타내었다. 포충 낭액과 유구낭미충 낭액을 10∼15% linear gradient gel에서 SDS-PAGE를 실시한 바 포충 낭액에는 모두 19개 분획이, 유구낭미충 낭액에는 23개 분획이 나타났고 그 중 64, 35, 22, 7 kDa 분획이 두가지 낭액에 모두 나타나고 있었다. SDS-PAGE로 분리한 각낭액 분획을 항원으로 포충증과 유구낭미충증 환자 혈청을 반응시키고 반응분획을 발색시킨 바(면역얼룩법, immunoblot), 포충증 환자혈청은 포충 낭액의 145, 140, 135, 125, 117, 110, 100, 86, 64, 52, 45, 39, 35, 29, 24, 22, 17, 12 및 7 kDa분획에 반응하였고 유구낭미충 낭액에 대해서는 135, 110, 100, 86, 64, 45, 39, 35 및 24 kDa분획에 반응하였다. 또 유구낭미충증 환자혈청은 유구낭미충 낭액의 135, 130, 110, 105, 86, 72, 64, 57, 52, 45, 39, 55, 24, 22, 15, 10 및 7 kDa분획에 반응하였고 포충 낭액에는 135, 100, 86, 64, 52, 39, 35, 29 및 24 kDa 분획에 반응하였다. 이상의 결과에서 포충 및 유구낭미충 낭액에는 SDS-PAGE로 분리되는 분획중 135, 100, 86, 64, 39, 35 및 24 kDa 분획이 교차반응에 관여하는 공통항원 분획으로 판단되며 포충 낭액의 7 kDa 및 유구낭미충 낭액의 낭액의 15,10 및 7 kDa 분획은 특이항원 분획으로 생각된다.

• Parasites, Hosts and Diseases
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• 제55권4호
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• pp.429-431
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• 2017

Hydatid cyst is usually located in the liver and lungs, rare cases showing localization in other organs or tissues. In the unusual location, echinococcosis is an excluding diagnosis that is established only after microscopic evaluation. Our first case occurred in a 67-year-old female previously diagnosed with pulmonary tuberculosis and hospitalized with persistent pain in the hip joint. The clinical diagnosis was tuberculosis of the joint, but the presence of the specific acellular membrane indicated a hydatid cyst of the synovial membrane, without bone involvement. Fewer than 25 cases of joint hydatidosis have been reported in literature to date. In the second case, the intramural hydatid cyst was incidentally discovered at autopsy, in the left heart ventricle of a 52-year-old male hospitalized for a fatal brain hemorrhage, as a result of rupture of an anterior communicating artery aneurysm. The conclusion of our paper is that echinococcosis should be taken into account for the differential diagnosis of cystic lesions, independently from their location.

• Parasites, Hosts and Diseases
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• 제53권6호
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• pp.785-788
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• 2015

Cystic echinococcosis (CE) caused by Echinococcus granulosus is a major public health problem worldwide, including Turkey. The aim of the current study was to identify the strains and to estimate the potential risk factors of E. granulosus in operated pediatric cases in eastern Turkey. Ten pediatric patients (7 boys and 3 girls) living in rural areas, with ages ranging from 3 to 15 years old and various clinical histories, were included in this study. Eight patients had only liver hydatid cyst, while 1 patient had liver and lung hydatid cyst and the other liver, lung, and spleen, together. There were 2 ruptured liver cysts. After surgery, during follow-up, no increase was observed in hemagglutination levels, there were no mortalities, and there was no evidence of recurrence at 2 years post operation in all patients. Molecular analysis was performed on hydatid cyst samples obtained from the 10 pediatric cases. According to mt-12S rRNA PCR results, all cases were found to be G1/G3 cluster of E. granulosus sensu stricto.

• Journal of Chest Surgery
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• 제41권4호
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• pp.527-531
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• 2008

포충증은 단방조충의 유충감염에 의한 기생충 질환으로 전세계적으로 발생하고 있으나 국내에서는 매우 드문 질환이다. 34세 몽고 남성이 기침과 흉부불쾌감을 주소로 내원하였고 흉부 전산화 단층촬영에서 우폐 상엽에 낭종이 발견되었다. 낭종은 우폐 상엽의 쐐기절제술로 제거되었고 병리학적 검사상 포충낭종으로 확진되었다. 술 후 재발 방지를 위하여 알벤다졸을 투약하였다. 유행지역에서 온 외국인의 폐포충증 1예를 수술 치험하였기에 문헌고찰과 함께 보고하는 바이다.

• Parasites, Hosts and Diseases
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• 제43권1호
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• pp.15-18
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• 2005

The diagnosis of human hydatidosis is primarily made using radiological and serological methods. Radiological methods are generally of low specificity and serological methods lack sensitivity, especially for pulmonary disease. In this study the capabilities of a new rapid test, the hydatid antigen dot immunobinding assay (HA-DIA), which was developed for the diagnosis of pulmonary hydatidosis, were studied and compared with another immunodiagnostic method, indirect hemagglutination (IHA). The study subjects included 18 patients, 9 women, 9 men; range 7 to 63 years; mean 30 years, with surgically proven pulmonary hydatidosis, a control group comprised of 14 patients; viral respiratory infections (1), cirrhosis (2), connective tissue disease (2), taeniasis (3), and 6 healthy donors. We found that the HA-DIA test had a sensitivity of $67\%$ and specificity of $100\%$, and that the IHA test had a sensitivity of $50\%$ and specificity of $100\%$. We conclude that HA-DIA is a simple, rapid, low cost assay that does not require instrumentation and has a higher sensitivity than IHA for the diagnosis of pulmonary hydatidosis.

• Parasites, Hosts and Diseases
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• 제50권4호
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• pp.357-360
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• 2012

A 25-year-old Uzbek male presented with right upper abdominal pain for 20 days. On radiologic studies, a huge cystic mass was noticed in the right liver which was suspected as parasitic. The patient received right hepatic segmentectomy (segment 7), and the surgically resected mass was confirmed as cystic echinococcosis (CE), measuring 10.5 cm in its diameter. The inner surface of the cyst was bile-stained. The patient was discharged on the 8th hospital day, and was rechecked 6 months after the surgical intervention without any evidence of recurrence. The present report describes findings of an imported case of CE which represented ultrasound images of the 'ball of wool'.

• Parasites, Hosts and Diseases
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• 제48권3호
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• pp.263-265
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• 2010

Echinococcosis is a multisystem disease and has propensity to involve any organ, an unusual anatomical site, and can mimic any disease process. Primary peritoneal echinococcosis is known to occur secondary to hepatic involvement but occasional cases of primary peritoneal hydatid disease including pelvic involvement have also been reported. We report here 1 such case of primary pelvic hydatidosis mimicking a malignant multicystic ovarian tumor where there was no evidence of involvement of the liver or spleen. Our patient, a 27-year-old female, was detected to have a large right cystic adnexal mass on per vaginal examination which was confirmed by ultrasonography. Her biochemical parameters were normal and CA-125 levels, though mildly raised, were below the cut off point. She underwent surgery and on exploratory laparotomy, another cystic mass was found attached to the mesentery of the small gut. The resected cysts were processed histopathologically. On cut sections both large cysts revealed numerous daughter cysts. Microscopic examination of fluid from the cysts revealed free scolices with hooklets and the cyst wall had a typical laminated membrane with inner germinal layer containing degenerated protoplasmic mass. The diagnosis of pelvic hydatid disease was confirmed and patient was managed accordingly. Hydatid disease must be considered while making the differential diagnosis of pelvic cystic masses, especially in endemic areas.

• Tuberculosis and Respiratory Diseases
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• 제70권4호
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• pp.338-341
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• 2011

Hydatid disease is caused by the larval stage of taenia $Echinococcus$, which endemic in the Mediterranean region. Recently, the prevalence of the disease has increased worldwide due to an increase in the frequency of travel and immigration. As the infested larvae migrate through the bloodstream, the final destination is most commonly the liver or lungs; direct pleural invasion is very rare. A 50-year-old diabetic Korean man presented with an incidentally noted 2 cm right pleural nodule. On follow up imaging after three months, its size had increased. To confirm the diagnosis of the lesion, surgical excision was performed. Histopathological examination showed the diagnosis of a hydatid cyst. The patient had no history of overseas travel, but lives in an urban area where many foreign workers from endemic countries reside. This is the first reported case of primary pleural hydatid disease in a non-endemic country.

• Parasites, Hosts and Diseases
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• 제38권3호
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• pp.191-194
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• 2000

Genus specific antigenicity of the 10 kDa protein in cyst fluid (CF) of Taenia solium metacestodes was demonstrated by comparative immunoblot analysis. When CFs from taeniid metacestodes of T. saginata, T. solium, T. taeniaeformis and T. crassiceps were probed with specific monoclonal antibody (mAb) raised against 150 kDa protein of T. solium metacestodes, specific antibody reactions were observed in 7 and 10 kDa proteins of T. solium and in 7/8 kDa of T. saginata, T. taeniaeformis and T. crasiceps. The mAb did not react with any protein in hydatid fluid of Echinococcus granulosus and E. multilocularis. This result revealed that the 10 kDa peptide of T. solium metacestodes and its equivalent proteins of different Taenia metacestodes are genus specific antigens that are shared among different Taenia species.