• 제목/요약/키워드: Early development

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생쥐 배아 동결시 전핵의 발생시기가 생존률과 발생률에 미치는 영향 (Effects of the Age of Pronucleate Ova on Survival and Development in Cryopreservation of Mouse Embryos)

  • 양현원;강희규;최규완;차영범;이승재;박종민
    • Clinical and Experimental Reproductive Medicine
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    • 제20권1호
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    • pp.31-36
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    • 1993
  • The effects of freezing and 1,2-propanediol on early and late pronucleate stage mouse ova were investigated in terms of survival after thawing and development in vitro. The samples were divided into two groups according to different age in pronucleate ova: ova in(1) early pronuclear stage with two distant pronuclei at 18h after hCG injection, and (2) late pronuclear stage with adjacent pronuclei at 30h. Zygotes in the late pronuclear stage have been proven to be more resistant to 1,2-propanediol, showing a significantly higher developmental rate than zygotes in early stage (80.3 versus 66.3%, <0.05), but survival rate was similar in the two groups (91.0 versus 93.5%). After freezing and thawing, survival and developmental rates were decreased in both groups when compared to the control group (54.3 versus 92.3%, 47.7 versus 73.3%. respectively). And developmental rate in the late pronuclear stage zygotes showed significantly higher than in early (55.4 versus 40.0%) after thawing. In conclusion, early pronucleate mouse ova have a lower developmental capacity in vitro and a lower survival rate after freezing and thawing than late ova. These findings suggest that the timing of freezing could be important for survival and further development in vitro in cryopreservation of human pronucleate ova.

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초기재령 콘크리트의 응결특성 모델링 (Modeling of the Setting Characteristics of Early-age Concrete)

  • 조호진;송하원;변근주
    • 한국콘크리트학회:학술대회논문집
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    • 한국콘크리트학회 2002년도 가을 학술발표회 논문집
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    • pp.391-396
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    • 2002
  • The so called setting is defined as the onset of rigidity in fresh concrete. In the analysis of the early-age concrete behavior, we consider fresh concrete as a structural element immediately after mixing. But for the activation of real structural behavior of fresh concrete, it takes some time after the beginning of hydration reaction. So, the very early age deformations due to hydration heat and shrinkage which occur before the setting do not produce restraint stresses. In this paper, we propose a setting characteristic model based on the so called percolation theory. From the analysis using the model, the influence of curing temperature is investigated and analytical results are compared with experimental results. From the comparison, the validity of proposed model is verified. This model is also applied to evaluate stress development in a temperature-stress test machine (TSTM) specimen and then the effect of setting time on the stress development is discussed.

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Early Life History of Coreoperca herzi in Han River, Korea

  • Park, Jae-Min;Jeon, Hyung-Bae;Suk, Ho Young;Cho, Seong-Jang;Han, Kyeong-Ho
    • 한국발생생물학회지:발생과생식
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    • 제24권1호
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    • pp.63-70
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    • 2020
  • This study aimed to investigate early life of Coreoperca herzi living in Han River and compare morphological differences between different groups during the development in order to provide basic data for relevant taxonomic research. On average, one female individual spawned 541 to 861 eggs (average 701) at once. After 259 hours, the tail broke out of the egg membrane and hatching began. Immediately after hatching, the larvae were average 7.81±0.10 mm (n=5) in total length. 60 days the juvenile was average 35.9±1.30 mm (n=5) in total length. The white spots spread to the rest of the body, rending the same pattern as that on the body of their broodstock fish.

Technology Development of Early Diagnosis for Pregnancy in Deer

  • Lee, J. H.;Park, S.J.;Ryu, I. S.;Kim, I.C.;Lee, D.W.;Seo, K.H.;Heo, T.H.;Yu, C.H.;Kim, C.K;Baek, S.H.;Son, D.S.
    • 한국동물번식학회:학술대회논문집
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    • 한국동물번식학회 2002년도 춘계학술발표대회 발표논문초록집
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    • pp.81-81
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    • 2002
  • The deer was inseminated at the breeding season, which only shows appearance of the estrus cycles. Early diagnosis of pregnancy is very useful to select non-pregnant does and also very important to decide re-inseminations or mating for producing of calves. Therefore, for the development of techniques on the early diagnosis of pregnancy of deer, the results of this study were summarized as following. (omitted)

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Support Vector Machine을 이용한 초기 소프트웨어 품질 예측 (Early Software Quality Prediction Using Support Vector Machine)

  • 홍의석
    • 한국IT서비스학회지
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    • 제10권2호
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    • pp.235-245
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    • 2011
  • Early criticality prediction models that determine whether a design entity is fault-prone or not are becoming more and more important as software development projects are getting larger. Effective predictions can reduce the system development cost and improve software quality by identifying trouble-spots at early phases and proper allocation of effort and resources. Many prediction models have been proposed using statistical and machine learning methods. This paper builds a prediction model using Support Vector Machine(SVM) which is one of the most popular modern classification methods and compares its prediction performance with a well-known prediction model, BackPropagation neural network Model(BPM). SVM is known to generalize well even in high dimensional spaces under small training data conditions. In prediction performance evaluation experiments, dimensionality reduction techniques for data set are not used because the dimension of input data is too small. Experimental results show that the prediction performance of SVM model is slightly better than that of BPM and polynomial kernel function achieves better performance than other SVM kernel functions.

'새노래부르기' 활동에서 다루고 있는 유아교사의 음악적 개념과 지도의 어려움 (Early Childhood Teachers' Practice and Difficulties with Musical Concepts Treated in the 'Sing-a-New-Song' Activity)

  • 박미경;엄정애
    • 아동학회지
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    • 제29권3호
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    • pp.93-113
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    • 2008
  • This study examined musical concepts of early childhood teachers with the 'Sing-a-New-Song' activity and problems teachers face in the application of musical concepts. Participants were 10 kindergarten teachers; data were collected through lesson plans, videos of classes, and interviews with teachers. Results showed that (1) selection of songs focused on words of a song rather than musical concepts; ignoring development of the musical level of the children. (2) Goal-setting ignored musical concepts. (3) Class management confused musical concepts with other concepts. (4) No evaluation of musical concepts was undertaken. Problems included teachers' lack of knowledge of musical development in young children, insufficient understanding and limited application of musical concepts, and low expectations regarding music as a subject of instruction.

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동절기 고강도콘크리트의 시공에 있어서 초기동해 방지에 관한 실험적 연구 (An Experimental Study on the Early Frost Resistance Properties of High-Strength Concrete in Winter Concreting)

  • 권영진
    • 한국건축시공학회:학술대회논문집
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    • 한국건축시공학회 2001년도 학술논문발표회
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    • pp.76-81
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    • 2001
  • Recently, the structure is higher and larger, so that the application of high-strength concrete is increased, And as the development of construction skills, it is possible to place during the winter. Concrete work during winter is indispensible to shorten time of completion and cut costs. When concrete work during winter is placed, it has anxiety that concrete freeze at low temperature. As repetition of concrete's freezing cause reduction of durability, it is necessary for mixing to pay attention to air content and W/C ratios. Accordingly, in this study, we estimate the frost resistance by air content and W/C ratios, and development of strength after early-frost damage in the high-strength concrete during the cold weather. In this study, it could be confirmed that factors which were air content, W/C ratios and early curing period, affected on the frost resistance.

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폐암과 보험의학 (Lung cancer and insurance medicine)

  • 이신형
    • 보험의학회지
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    • 제31권1호
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    • pp.34-36
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    • 2012
  • Lung cancer such as small cell lung cancer(SCLC) and non small cell lung cancer(NSCLC) have high mortality rate, so, we insurance doctors have little interest in their risk. But nowadays there's a lot of development in targeted therapy of NSCLC. Screening by CT scanning and early resection strategy also shows better prognosis. It is helpful for underwriters and insurance doctors to review the current development of targeted therapy of NSCLC and estimation of extra-risk of early lung cancer. The preferred treatment option for patients whose tumors contain EGFR-activating mutations are one of the EGFR-directed tyrosine kinase inhibitors, such as gefitinib or erlotinib. In patients with NSCLC whose tumors harboured an ALK rearrangement, there was 61% objective response rate to crizotinib in the phase 1 study. The median survival progression-free survival was 10 months. Mortality analysis of early lung cancer who were detected by CT screening, MR of 105% and EDR of 1‰ were calculated.

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디젤엔진용 고장 및 예측진단 기술 개발 (Development of the Fault and Early Diagnosis Technology for Diesel Engine)

  • 박종일;류길수;조권회;소명옥;김태진;원라경;장태린;안종갑
    • 한국마린엔지니어링학회:학술대회논문집
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    • 한국마린엔지니어링학회 2005년도 전기학술대회논문집
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    • pp.321-325
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    • 2005
  • These days, it is needed that more stability and reliability of Diesel engine. So it is essential that a systematic and comprehensive fault diagnosis analysis technology. this technology makes fault diagnosis analysis system more efficient. Expert System is required to make fault diagnosis analysis system. In this paper, fault and early diagnosis system is implemented to use Expert System development tools.

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Limnoperna fortunei의 초기발생 및 유생에 관한 연구 (Study on the Early Development and Larvae of Limnoperna fortunei)

  • 최신석;신창남
    • 한국패류학회지
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    • 제1권1호
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    • pp.5-12
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    • 1985
  • The maturity of gonads, early development of the fertilized egg, spawning period, and morphogenesis of larvae in Limnoperua fortunei were studied from October, 1981 to November, 1982 as on attempt to identify its life cycle. 1) Active motility of its sperm was observed at late May, and matured egg could be found at late June. 2) It was estimated that the spawning was occured from late August. This species was belong to the short-term breeder because it finished its spawning within 20 days. 3) It has free-living trochophore and D-shaped larva stage. The shell lengths of early, middle, and D-larval stage were $140.0{\mu}m$, $167.6{\mu}m$ and $210.0{\mu}m$, respectively. The shell heigths of each stage were $97.3{\mu}m$, $137.6{\mu}m$ and $178.2{\mu}m$, respectively.

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