• Korean Journal of Ecology and Environment
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• v.49 no.4
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• pp.343-353
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• 2016

Oligochaetes distribute widely in freshwater ecosystem, and some species are used as bioindicators for water quality assessment because they are tolerant to organic enrichment. They are acknowledged for potential for environmental health recovery of organic polluted environment. There are a lot of studies on ecology and toxicity assessment using oligochaetes in aquatic environment. In this study, we reviewed literature on ecotoxicology of aquatic oligochaetes. We searched literature from a database 'google scholar' by using keywords such as aquatic, oligochaete, and toxicity. The literature were summarized according to publication years, species, test methods, and chemicals. We obtained 133 articles published from 1953 to 2015 from the database. Among them, 58 papers(43.6% of total) have been published in 1990s. Three species(Lumnbriculus variegatus, Tubifex tubifex, and Limnodrilus hoffmeisteri) have been used most frequently in the study. Different species displayed different toxicological responses to different toxic chemicals. The results on the ecotoxicological study with aquatic oligochaetes revealed the possibility of the development for early warning system using aquatic oligochaetes to monitor aquatic ecosystem disturbance.

• Journal of International Academy of Physical Therapy Research
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• v.11 no.1
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• pp.2005-2011
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• 2020

Background: Motor imagery is the mental representation of an action without overt movement or muscle activation. However, few previous studies have demonstrated motor imagery training effects as an objective assessment tool in patients with early stroke. Objective: To investigate the effect of motor imagery training on Somatosensory Evoked Potentials (SSEP) and upper limb function of stroke patients. Design: A quasi-experimental study. Methods: Twenty-four patients with stroke were enrolled in this study. All subjects were assigned to the experimental or control group. All participants received traditional occupational therapy for 30 minutes, 5 times a week. The experimental group performed an additional task of motor imagery training (MIT) 20 minutes per day, 5 days a week, for 4 weeks. Both groups were assessed using the SSEP amplitude, Fugl-Meyer assessment of upper extremity (FMA UE) and Wolf motor function test. Results: After the intervention, the experimental group showed significant improvement in SSEP amplitude and FMA UE than did the control group. Conclusion: These findings suggest that the MIT effectively improve the SSEP and upper limb function of stroke patients.

• The Journal of Internal Korean Medicine
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• v.40 no.5
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• pp.999-1006
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• 2019

Objectives: The purpose of this study was to report the improvement of symptoms by Korean medicine in acute hemorrhagic infarction. Method: The patient was diagnosed with a cerebral infarction of the right temporal lobe accompanied by cerebral hemorrhage of the left basal ganglia. He did not receive intravenous thrombolytic treatment. Sunghyangjungi-san-gamibang was initially administered, and Gami-daebo-tang was administered during the recovery phase, together with Uhwangchungsim-won, Simjeok-hwan, and acupuncture. The prognostic observation was conducted using the manual muscle test (MMT), the Korean version of the modified Bathel index (K-MBI), and subjective assessment. Results: After Korean medicine treatment, the K-MBI score was improved from 52 to 93. The MMT score and subjective assessment also showed improvement. Conclusions: For patients who cannot be treated with intravenous thrombolytic treatment, Korean medicine treatment is effective during the early and recovery stages of stroke.

• Natural Product Sciences
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• v.24 no.4
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• pp.219-224
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• 2018

During the screening for cytotoxic compounds from plants grown in Korea, Betula platyphylla (BP) showed potent activity against the adenocarcinomic human alveolar basal epithelial A549 cell line. To identify the cytotoxic components from BP, the $CH_2Cl_2$ fraction with the most significant cytotoxic effect was applied to the column chromatographies. Seven compounds were isolated: lupeol (1), betulinic acid (2), (-)-rhododendrol (3), platyphyllenone (4), platyphyllone (5), (-)-centrolobol (6), and oleanolic acid (7). Among them, three diarylheptanoids (4 - 6) exhibited cytotoxicity toward A549 cells. Especially, $50{\mu}M$ of 4 reduced A549 cell viability to $18.93{\pm}0.82%$ compared to control ($100.00{\pm}21.48%$). Lactate dehydrogenase (LDH) leakage and intracellular reactive oxygen species (ROS) production were also induced by $50{\mu}M$ 4. This is the first report on the cytotoxic effect of BP-derived diarylheptanoids 4-6 against A549 cells. The compound 4 may be useful for the development of early hit compounds for non-small cell lung carcinoma, but the consideration about selectivity of 4 is required since 4 also showed the cytotoxicity in the human normal lung epithelial BEAS-2B cell line.

• Nuclear Engineering and Technology
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• v.51 no.4
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• pp.1024-1031
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• 2019

The Molten Salt Fast Reactor (MSFR) with its liquid circulating fuel and its fast neutron spectrum calls for a new safety approach including technological neutral methodologies and analysis tools adapted to early design phases. In the frame of the Horizon2020 program SAMOFAR (Safety Assessment of the Molten Salt Fast Reactor) a safety approach suitable for Molten Salt Reactors is being developed and applied to the MSFR. After a description of the MSFR reference design, this paper focuses on the identification of the Postulated Initiating Events (PIEs), which is a core part of the global assessment methodology. To fulfil this task, the Functional Failure Mode and Effect Analysis (FFMEA) and the Master Logic Diagram (MLD) are selected and employed separately in order to be as exhaustive as possible in the identification of the initiating events of the system. Finally, an extract of the list of PIEs, selected as the most representative events resulting from the implementation of both methods, is presented to illustrate the methodology and some of the outcomes of the methods are compared in order to highlight symbioses and differences between the MLD and the FFMEA.

• International Journal of Computer Science & Network Security
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• v.21 no.5
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• pp.23-30
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• 2021

In recent years, hazardous flash flooding has caused deaths and damage to infrastructure in Saudi Arabia. In this paper, our aim is to assess patterns and trends in climate means and extremes affecting flash flood hazards and water resources in Saudi Arabia for the purpose to improve risk assessment for forecast capacity. We would like to examine temperature, precipitation climatology and trend magnitudes at surface stations in Saudi Arabia. Based on the assessment climate patterns maps and trends are accurately used to identify synoptic situations and tele-connections associated with flash flood risk. We also study local and regional changes in hydro-meteorological extremes over recent decades through new applications of statistical methods to weather station data and remote sensing based precipitation products; and develop remote sensing based high-resolution precipitation products that can aid to develop flash flood guidance system for the flood-prone areas. A dataset of extreme events has been developed using the multi-decadal station data, the statistical analysis has been performed to identify tele-connection indices, pressure and sea surface temperature patterns most predictive to heavy rainfall. It has been combined with time trends in extreme value occurrence to improve the potential for predicting and rapidly detecting storms. A methodology and algorithms has been developed for providing a well-calibrated precipitation product that can be used in the early warning systems for elevated risk of floods.

• International conference on construction engineering and project management
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• 2009.05a
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• pp.794-799
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• 2009

The temperature control of in-place concrete is the most important factor for an early age of curing concrete. Heat stress of mass concrete caused by the heat of hydration can induce the crack of concrete, and a frost damage from cold weather casting concrete results defect on compressive strength and degradation of durability. Therefore, success and failure of concrete work is dependant on the measurement and control of concrete temperature. In addition, the compressive strength assessment of in-place concrete obtained from the maturity calculated from the history of temperature make a reduction of construction cycle time, possible. For that purpose, wireless temperature measuring system was developed to control temperature and assess strength of concrete. And, it was possible to monitor the temperature of concrete over 1km apart from site office and to take a proper measure; mesh-type network was developed for wireless sensor. Furthermore, curing control system that contains the program capable to calculate the maturity of concrete from the history of temperature and to assess the compressive strength of concrete was established. In this study, organization and practical method of developed curing control system are presented; base on in-place application case.

• International conference on construction engineering and project management
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• 2022.06a
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• pp.25-32
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• 2022

As a project delivery method, Design-Build (DB) has provided owner, architect, and contractor groups with a process of early design and rapid construction for the past three decades. Although there are many benefits to using standard DB, dissatisfaction has arisen due to limitations to innovate, limited owner involvement during design, and often lengthy procurement. Progressive Design-Build (PDB) has become an appealing alternative providing benefits not seen with standard DB. This paper investigates how PDB impacts a project and how it compares against standard DB; it also presents a proposed framework for evaluating the owner's responsibility and assessment of a project, which we named the "Four Pillars of Project Success". The four pillars are defined with respect to an owner's responsibility and assessment of a project, including project predictability, project risk, project schedule, and project cost. We conducted a literature review, examined several public project case studies, analyzed PDB project information collected by the Design-Build Institute of America (DBIA), and held stakeholder interviews with owners, contractors, and architects who have used both PDB and standard DB. This paper offers insight into PDB's structure and outcomes so an owner group can make an informed decision when considering PDB as their next construction contracting method.

• Nuclear Engineering and Technology
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• v.56 no.3
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• pp.866-872
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• 2024

Design Extension Conditions (DEC)-A assessments of the operating nuclear power plants are generally considered for the purpose of getting additional safety demonstrations of their capability to undergo conditions that are generally more severe than DBAs by features implemented in the design and accident management measures. The pursued methodology is generally based upon Best Estimate approaches aiming at verifying that the safety limits in terms of integrity of the barriers against eventual large or early releases of radioactive material are fulfilled. These aspects are nowadays being experimentally and analytically addressed within the OECD/NEA experimental projects like the ATLAS and PKL series where a set of DEC-A experiments are considered. In this paper, experiments related to SBLOCA at the vessel upper head of the pressurized vessel of ATLAS and PKL are analytically assessed using the CATHARE code. These experiments includes issues related to common cause failure of the safety injection system and operator actions for preventing core excessive overheating. It is shown that, on the one hand, the safety features embedded in the design together with the operator actions are capable to prevent the progression towards a severe accident state and on the other hand, the code prediction capabilities for such scenario are generally good but still to be enhanced.

• Dementia and Neurocognitive Disorders
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• v.22 no.1
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• pp.1-15
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• 2023

The Seoul Neuropsychological Screening Battery (SNSB) is known as a representative comprehensive neuropsychological evaluation tool in Korea since its first standardization in 2003. It was the main neuropsychological evaluation tool in the Clinical Research Center for Dementia of South Korea, a large-scale multi-center cohort study in Korea that was started in 2005. Since then, it has been widely used by dementia clinicians, and further solidified its status as a representative dementia evaluation tool in Korea. Many research results related to the SNSB have been used as a basis for the diagnosis and evaluation of patients in various clinical settings, especially, in many areas of cognitive assessment, including dementia evaluation. The SNSB version that was updated in 2012 provides psychometrically improved norms and indicators through a model-based standardization procedure based on a theoretical probability distribution in the norm's development. By providing a score for each cognitive domain, it is easier to compare cognitive abilities between domains and to identify changes in cognitive domain functions over time. Through the development of the SNSB-Core, a short form composed of core tests, which also give a composite score was provided. The SNSB is a useful test battery that provides key information on the evaluation of early cognitive decline, analysis of cognitive decline patterns, judging the severity of dementia, and differential diagnosis of dementia. This review will provide a broad understanding of the SNSB by describing the test composition, contents of individual subtests, characteristics of standardization, analysis of the changed standard score, and related studies.