• 대한치위생과학회지
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• 제6권2호
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• pp.173-182
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• 2023

서론: 본 연구 우리나라 성인 청년, 중년, 장년층의 구강건강 관련 활동 제한이 삶의 질에 미치는 영향을 규명하고 성인의 구강건강관리의 중요성과 생활습관의 개선으로 삶의 질을 높이기 위한 중재전략을 마련하는데 기여하고자 하였다. 연구방법: 제8기 1차년도(2019) 국민건강영양조사 원시자료를 사용였으며, 우리나라 성인 청년 만19~29세, 중년 만30~49세, 장년 만50~64세를 대상으로 하였다. 인구사회학적 특성, EQ-5D, HINT-8과 구강 관련 활동 제한 변수로는 치통 경험 여부, 저작 불편 호소 여부, 씹기 문제, 말하기 문제를 사용하여 분석하였다. 성인의 구강 관련 활동 제한에 따른 삶의 질에 대한 차이와 삶의 질에 미치는 영향 요인을 조사하기 위해 분산분석, 다중 회귀 분석을 실시하였다. 연구결과:청년, 중년, 장년의 구강건강 관련 활동제한에 따른 EQ-5D와 HINT-8 차이는 구강 관련 활동 제한 변수에서 모두 통계적으로 유의하였다(p≦0.05). 전체 성인의 EQ-5D에 영향을 미치는 요인은 지역(읍,면,동), 성별, 가구 월 소득, 교육수준, 기초생활수급 여부, 경제활동 여부, 주관적 구강건강 상태, 치통 경험 여부, 씹기 문제, 말하기 문제, 저작 시 불편 호소 여부의 변수에서 통계적으로 유의하게 나타났다(p≦0.05). 전체 성인의 HINT-8 에 영향을 미치는 요인은 성별, 가구 월 소득, 교육수준, 기초생활수급 여부, 경제활동 여부, 치통 경험 여부, 씹기 문제, 말하기 문제, 저작 시 불편 호소 여부의 변수에서 통계적으로 유의하게 나타났다(p≦0.05). 결론: 성인의 신체적, 정신적, 사회적으로 준비된 노년기를 맞이할 수 있도록 하여 노년의 삶의 질을 높이기 위한 다각적 방안이 필요하다. 본 연구 결과를 기초로 성인의 구강건강증진과 삶의 질 개선을 위한 성인구강보건사업 프로그램이 개발되어야 할 것이다.

• 대한약리학회지
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• 제13권2호
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• pp.11-17
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• 1977

흰쥐 적출 좌심방근을 사용하여 부자 부타놀 분획의 강심작용의 potassium-dependency 여부를 기존 강심제인 ouabain을 대조 약물로 하여 검토한 결과는 다음과 같다. 1) 흰쥐 적출 좌심방근은 ouabain에 대해서는 가토 등의 실험 동물에 비해 현저한 내성을 보였다. 2) 심방근의 수축장력은 세포의 potassium 농도를 2mM에서 10mM까지 변화 시켰을때 유의한 수축력의 변화를 볼 수 없었다. 3) Potassium 2mM에서의 ouabain의 강심 효과는 6, 10mM에서 보다 현저한, 즉 potassium dependent한 강심 효과를 나타내었으나, 부자 부타놀 분획의 강심효과는 potassium-independent한 양상이었다. 4) 흰쥐 심방근의 흥분성은 생리적 potassium 농도인 6mM에서 가장 높았고 저 농도 및 고농도에서는 흥분성의 감소를 보였으며 본 실험에 사용된 ouabain $2{\times}10^{-5}M$, 부자 부타놀 분획 $5{\times}10^{-4}gm/ml$의 농도는 심방근 흥분성에 별 영향을 주지 못했다.

• Journal of Preventive Medicine and Public Health
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• 제55권3호
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• pp.234-242
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• 2022

Objectives: This study assessed the validity and reliability of the Health-related Quality of Life Instrument with 8 Items (HINT-8) in patients with diabetes. HINT-8 is a newly-developed, generic health-related quality of life (HRQoL) instrument. Methods: Three HRQoL instruments-HINT-8, EuroQoL 5-Dimension 5-Level (EQ-5D-5L), and Short Form Health Survey version 2.0 (SF-36v2)-were provided to 300 patients with diabetes visiting a tertiary hospital for follow-up visits in Korea. The HRQoL scores obtained using the HINT-8 were evaluated for subgroups with known differences based on demographics and diabetes-related characteristics (known-group validity). The mean scores of the instruments were compared between groups segmented by their responses to the HINT-8 (discriminatory ability). Correlation coefficients of the HINT-8 with other instruments were calculated (convergent and divergent validity). The Cohen kappa and intra-class correlation coefficient (ICC) were also evaluated (test-retest reliability). Results: The average HINT-8 indexes were lower among women, older, and less-educated subjects. Subjects who did not list any problems on the HINT-8 had significantly higher HRQoL scores than those who did. The correlation coefficients of the HINT-8 with the EQ-5D-5L index and EuroQoL visual analogue scale were 0.715 (p<0.001) and 0.517 (p<0.001), respectively. The correlation coefficients between the HINT-8 index and the scores of 8 domains of the SF-36v2 ranged from 0.478 (p<0.001) to 0.669 (p<0.001). The Cohen kappa values for the HINT-8 ranged from 0.268 to 0.601, and the ICC of the HINT-8 index was 0.800 (95% confidence interval [CI], 0.720 to 0.860). Conclusions: This study showed that the HINT-8 is a valid and reliable HRQoL instrument for patients with diabetes.

• 보건의료산업학회지
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• 제5권2호
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• pp.77-89
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• 2011

This study conducted a secondary analysis by using original data of performed by Korea Institute for Health and Social Affairs to know factors affecting determinants of health using Lalonde model for the adults aged over 19 years living in Korea. The survey was conducted in 2009 and it evaluated finally 5,867 cases by excluding cases with no answer or a wrong answer. This study model adopted two categories of instrument measure health were objective (Average remaining lifetime) and subjective(EQ-5D) health status. The health determinants included in this study could be divided in to four categories, which were human biology, environment, lifestyle, and health care organization. The results were as follows. In the factors affecting average remaining lifetime, human biology were sex, ages, BMI, showed statistically significant difference, environment category were merry status, education showed statistically significant difference, lifestyle category were exercise, drunks showed statistically significant difference and health care organization category were vaccination, health screening showed statistically significant difference. In the factors affecting EQ-5D, human biology category and health care organization category showed with same average remaining lifetime, environment category were merry status, education, income showed statistically significant difference and lifestyle category were exercise, drunks, stress showed statistically significant difference. The results demonstrated that the best powerful factor was life style category and environment category, the least factor was health care organization category. So lifestyle style and environment category should be considered for the future health plan, budget allocation and the priority in the health care.

• 한방재활의학과학회지
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• 제33권1호
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• pp.97-108
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• 2023

The purpose of this study is to investigate the effectiveness of integrative Korean medicine treatment for patients who were diagnosed as acute fracture on pelvis. The patients were treated by Korean medicine as conservative management including acupuncture, pharmacopuncture, herbal medication and cupping for hospitalization periods. Numerical rating scale (NRS), EuroQol-5 dimensions (EQ-5D), Oswestry disability index (ODI), patient global impression of change (PGIC), self-walking distance and the changes of symptoms were measured to assess patients' improvement. NRS, ODI scores and EQ-5D definitely improved on 4 patients of 5 cases. NRS decreased from 6~7 to 3~5, ODI scores decreased from 62~75.11 to 40~52 and EQ-5D increased from 0.013~0.331 to 0.47~0.773. PGIC and self-walking distance were also enhanced after treatments. In conclusion, this study suggests that integrative Korean medicine could be effective treatment for acute pelvic fracture.

• 한국농촌간호학회지
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• 제9권2호
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• pp.59-70
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• 2014

Purpose: The present study was to done ascertain variables related to health-related quality of life (HRQOL) and their related factors in elders from urban or rural areas. Methods: Data were collected from raw material of the 2009 community health survey. Participants were 2,140 elders. Health related quality of life (HRQOL) was measured using EQ-5D. Data were analyzed with SPSS 13.0. Results: Mean EQ index score for urban elders was $0.78{\pm}0.23$, Mean EQ index score for rural elders was $0.82{\pm}0.16$. Rural elders had significantly higher EQ-5D index value compared to urban elders. The urban elder HRQOL model accounted for 33.6% of the variance due to depression, age, stress perception. The rural elder HRQOL model accounted for 23.5% of the variance due to exercising walking, skipping breakfast, depression in that order. In comparison, depression, skipping breakfast, livelihood, arthritis, stress perception, hours of sleep and age are strongly associated with HRQOL in both groups. Conclusion: Results indicate that significant differences in HRQOL between elders from the two areas and thus, confirm claims that welfare services for elders should be provided with consideration of the different needs of elders in the two areas, and in particular for addressing depression in elders.

• 동의신경정신과학회지
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• 제26권2호
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• pp.79-88
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• 2015

Objectives: The purpose of this study is to investigate the effects of the M&L Trauma Psychotherapy Program on: Impact of Event Scale - Revised (IES-R-K); Euro QOL-5 Dimension (EQ5D); Five-facet Mindfulness Questionnaire (FFMQ); and psychological tests. Methods: Eight middle-aged women subjected to domestic violence participated in the two-day M&L Trauma Psychotherapy Program. The Program was executed 5 times 2 days for about 3 hours. We evaluated IES-R-K, EQ5D, FFMQ, Beck Depression Inventory (BDI), State-Trait Anxiety Inventory (STAI), State-Trait Anger Expression inventory (STAXI) and SUDS before the Program and for four weeks afterwards, to analyze the effects of the M&L Trauma Psychotherapy Program. Results: The scores of IES-R-K, BDI, STAI-S, STAI-T, Hwa ST and Hwa CT decreased significantly (p<0.05). EQ5D scores increased significantly (p<0.05) and overall physical condition scale (VAS) increased. In the FFMQ scores, all five facet scores increased slightly. Scores of SUDS decreased significantly right after the program, and remained decreased four weeks later, rather than before the Program (p<0.05). Conclusions: The results suggested that the M&L Trauma Psychotherapy Program improved post-traumatic stress, quality of life and mindfulness skills, and had positive responses to psychological problems - depression, anxiety, anger and distress.

• 대한조현병학회지
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• 제20권2호
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• pp.37-43
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• 2017

Objectives : This study was aimed to investigate the associations of childhood trauma with psychopathology and clinical characteristics in patients with schizophrenia. Methods : This study enrolled 66 inpatients with schizophrenia. Korean Childhood Trauma Questionnaire (K-CTQ) and Life Event Questionnaire (LEQ) were administered to assess childhood trauma. Psychopatholgy and clinical characteristics were assessed with the Positive and Negative Syndrome Scale (PANSS), Beck Depression Inventory (BDI), Korean Version of Internalized Stigma of Mental Illness (K-ISMI), Perceived Stress Scale (PSS), and visual analogue scale of EuroQoL-5 Dimension Index (EQ-5D). Results : Total scores on K-CTQ were positively associated with scores on the BDI, K-ISMI, PSS, and PANSS and negatively associated with the score on the EQ-5D. Among subscales of K-CTQ, emotional abuse was significantly associated with all measures for psychopathology and clinical characteristics. Patients with physical abuse (36.5%), emotional abuse (30.2%), or bullying (30.6%) according to the LEQ showed sighificanlty higher the ISMI score and lower EQ-5D score. Emotional abuse and bullying were also significantly associated with higher scores on BDI and/or PSS. Conclusion : Our results suggest that childhood trauma negatively influences on internalized stigma, depression, perceived stress and quality of life in patients with schizophrenia. Clinicians should carefully evalute and manage childhood traumatic experience of patients with schizophrenia.

• 디지털융복합연구
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• 제17권6호
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• pp.247-255
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• 2019

본 연구는 만성 뇌졸중 환자에게 키네시오테이핑과 경피신경전기자극을 결합 적용하여 단일방법과 비교하기 위함이다. 본 연구는 뇌졸중환자 29명을 대상으로 테이핑군(10명), 경피신경전기자극군(10명), 테이핑과 경피신경전기자극 결합한 결합군(9명)으로 나누었다. 중재기간은 4주간 주 5회, 30분씩 실시하였다. 평가에는 Timed Up & Go(TUG)와 Berg balance Scale(BBS)를 이용하여 균형평가를 실시하였고 보행 평가는 Functional Gait Assessment(FGA)와 10-metre walk test를 이용하였다. 삶의 질 평가는 EuroQol-5 dimension (EQ-5D)를 이용하였다. 연구결과 세 군 모두에서 TUG, BBS, FGA, 10 meter walk test, EQ-5D에 유의한 개선이 나타났다(p<.05). 세 군간 중재효과 비교에서 결합군이 나머지 두 군보다 FGA에 유의한 증가를 보였다. 본 연구를 통해 경피신경전기자극과 테이핑 결합이 단일적용 보다 FGA에 더욱 효과적인 것을 알 수 있었다. 하지만 FGA를 제외하고 다른 변수간에 차이가 없었으므로 앞으로의 연구에서는 더 많은 대상자 수와 중재기간이 필요할 것으로 사료된다.

• 대한의료기공학회지
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• 제22권1호
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• pp.83-96
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• 2023

Objective : The purpose of this study is to report that patients with panic disorder were able to discontinue the psychotropic medication through Korean Medicine treatment alone. Methods : The patient diagnosed with panic disorder were hospitalized on the 9th and were treated steadily through outpatient treatment afterwards with herbal medicine, acupuncture, cupping therapy, and Whidam's Sugi therapy while taking the chemical. Treatment effects were evaluated through BAI, BDI, STAI-X-1, CSEI-s, GIS, NDI-K, and EQ-5D measurements. Results & Conclusions : The patient's anxiety was relieved and the psychotropic medication was discontinued, but it did not recur. And after inpatient treatment, he has been steadily receiving outpatient treatment on a regular basis, maintaining an improved state and leading a normal daily life.