• Title/Summary/Keyword: EQ-5D

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The Separation of Vanadium and Tungsten from Spent Selective Catalytic Reduction Catalyst Leach Solution by Alamine 336 (탈질 폐촉매 침출액으로부터 Alamine 336에 의한 바나듐과 텅스텐의 분리)

  • Seongsu Kang;Gyeonghye Moon;In-Hyeok Choi;Dakyeong Baek;Kyoungkeun Yoo
    • Resources Recycling
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    • v.33 no.3
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    • pp.30-37
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    • 2024
  • In this study, we investigated the separability of vanadium and tungsten from spent SCR (Selective Catalytic Reduction) catalyst leach solution by reduction of vanadium and solvent extraction using Alamine 336 and conducted experiments to optimize process conditions. It is difficult to separate vanadium and tungsten due to their similar chemical behavior, but tungsten can be selectively extracted from acidic solution when vanadium extraction is prevented by reducing anionic pentavalent vanadium to cationic tetravalent vanadium. The results showed that NaHSO3 was most suitable as a reducing agent, and the extraction efficiency of vanadium decreased and the separation efficiency increased as the amount of reducing agent added, reaction time, and temperature increased. When reducing NaHSO3 1.5 eq, 60 min, and 60℃, which are optimal conditions of reduction, vanadium and tungsten were effectively separated with vanadium extraction efficiency of 5.8%, tungsten extraction efficiency of 99%, and separation factor of vanadium and tungsten of 7,564.

The Effects of Hyperglycemia and Hyperlipidemia on Muscle Glycogen Utilization during Exercise in Rats (흰쥐에서 고혈당 및 고지질혈증이 운동 중 골격근 당원이용에 미치는 영향)

  • Ahn, Jong-Chul;Lee, Dong-Woo;Shon, Oog-Jin;Lee, Seuk-Kang
    • Journal of Yeungnam Medical Science
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    • v.16 no.1
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    • pp.34-42
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    • 1999
  • The effects of hyperglycemia and hyperlipidemia on utilization of muscle glycogen during 45 minute Session of treadmill running(26 m/min, 8% grade) were evaluated using Sprague Dawley rats, and the characteristics of the 4 different type of muscles, I.e., soleus, white and red gastrocnemius, and plantaris, on glycogen utilization were simultaneously investigated. Hyperglycemia was induced by 145-165 mg/dL of oral glucose administration, and hyperlipidemia was induced by combined treatment of intraperitoneal heparine injection of 444 uEq/L and 10 % intralipose oral adminstration. During the hyperglycemic trial, the glycogen utilization of plantaris muscle was decreased by 13 % in 45 minute session of treadmill running compared to the control trial(p<0.05), and the glycogen utilization of white gastrocnemius was also decreased. The sparing tendency of glycogen was observed in soleus and red gastrocnemius by 5-13 % during 30 and 45 minute session of treadmill running in hyperglycemic trial. There was no glycogen sparing effect of hyperlipidemia in soleus, red gastrocnemius and plantaris muscle subjected in this experiment during exercise. However, only a slight sparing tendency of white gastrocnemius muscle was observed. In summary, the glycogen sparing effect of hyperglycemia during exercise was observed in plantaris and white gastrocnemius muscles in rats. However, there was no glycogen sparing effect of hyperlipidemia in the 4 hindlimb muscles. It was observed that the glycogen sparing effect of hyperglycemia is more prominent in fast glycolytic muscle fibers.

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A Review of Questionnaire for the Clinical Trials on Chronic Low Back Pain (만성 요통 임상연구에 사용된 설문지 현황 고찰)

  • Kim, Doo-Hee;Shin, Woo-Suk;Lee, Jin-Won;Park, Won-Hyung;Cha, Yun-Yeop;Ko, Youn-Seok;Lee, Jung-Han;Chung, Won-Suk;Shin, Byung-Cheul;Song, Yun-Kyung;Go, Ho-Yeon;Sun, Seong-Ho;Jeon, Chan-Yong;Jang, Bo-Hyoung;Ko, Seong-Gyu
    • Journal of Korean Medicine Rehabilitation
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    • v.23 no.4
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    • pp.95-115
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    • 2013
  • Objectives The aim of this review is to provide fundamental data for low back pain scales which can be used in clinical trial. Methods We investigated the latest studies on chronic low back pain via PubMed. And we also investigated domestic studies through "http://oasis.kiom.re.kr". 95 research papers were analyzed. Scales were classified into pain scale, function scale, generic health status scale and psychological scale. Results 1) According to foreign clinical studies, Visual Analog Scale (VAS) and Numerical Rating Scale (NRS) were used 18 times as pain scale. Oswestry Disability Index (ODI) was used 20 times as function scale, Roland-Morris Disability Questionnaire (RMDQ) was 17, and Hannover Functional Ability Questionnaire (HFAQ) was used 3 times. 36-item Short Form Health Survey (SF-36) was used 13 times as generic health status scale, Euroqol-5 Dimentions Questionnaire (EQ-5D) was 11, and 12-item Short Form Health Survey (SF-12) was used 3 times. Fear-Avoidance Beliefs Questionnaire (FABQ) was used 9 times as psychological scale, Pain Catastrophizing Scale (PCS) and Tampa Scale for Kinesiophobia (TSK-R) both were used 3 times. 2) According to domestic clinical studies, VAS was used 37 times as pain scale, NRS was 11, and Short Form McGill Pain Questionnaire (SF-MPQ) was used 6 times. ODI was used 30 times as function scale, RMDQ was 2 times only. SF-36 was used once as generic health status scale and Beck's Depression Inventory (BDI) was used 3 times as psychological scale. Conclusions We recommend VAS or NRS as a measure to evaluate pain, and ODI as a measure to evaluate functional disability. And we also recommend SF-36 or SF-12 and EQ-5D as a measure to evaluate generic health status. Finally, we recommend FABQ for use in measuring psychological scale.

The Effect of Social Capital on Health-related Quality of Life of Residents in Integrated Changwon City: Using the Data of the 2013 Community Health Survey (통합창원시 3개 지역 주민들의 사회자본이 건강 관련 삶의 질에 미치는 영향: 2013년 지역사회건강조사를 중심으로)

  • Park, Bo-hyun;Oh, Younjae
    • Research in Community and Public Health Nursing
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    • v.26 no.4
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    • pp.342-354
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    • 2015
  • Purpose: The purpose of this study was to examine social capital and health-related quality of life (HRQoL) of residents who were living in the three regions(Masan, Jinhae, and Changwon) of integrated Changwon and to analyze the effect of social capital on HRQoL. Methods: This study used the Masan, Jinhae and Changwon data of the 2013 Community Health Survey. The social capital questionnaire consisted of three subdomains (trust, participation, and network). HRQoL was measured with the Korean-version EQ-5D. The effect of social capital on HRQoL was analyzed using multiple regression with controlling for general characteristics and health behavior. Results: The trust level of Masan citizen was highest among the three regions. Jinhae citizen showed the highest level of participation and network out of the three regions. Trust was not a significant influencing factor in any of the three models. Participation was a significant influencing factor in all of the three models. Network was a significant influencing factor only in the Masan model. Conclusion: Participation was the most important factor for health among the three social capital subdomains. Strategies for encouraging social participation are needed for health promotion for the residents of integrated Changwon.

Quality of Life of Family Members Living with Cancer Patients

  • Lee, Hyo Jung;Park, Eun-Cheol;Kim, Seung Ju;Lee, Sang Gyu
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.16
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    • pp.6913-6917
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    • 2015
  • Background: Due to the rapid progress of industrialization, the expansion of the nuclear family, and an increase in women's social activities, the burden of care of cancer patients has increased, so that all family members are now involved in care. We compared the health-related quality of life (HRQOL) between members of families of cancer patients (hereafter, cancer families) and members of cancer-free families (non-cancer families). Materials and Methods: The data were from the Community Health Survey (2012). The study population included respondents at least 30 years of age. Data were adjusted for the following covariates: sex, age, education, marital status, household income, economic activity, household type, chronic disease, and perceived health status. Frequency analysis, analyses of variance, and multiple linear regression analysis were performed. Results: Among 163,495 respondents, 3,406 (2.1%) were part of a cancer family and 160,089 (97.9%) were part of a non-cancer family. Cancer families had lower EQ-5D scores than non-cancer families. However, by subgroup, the scores had significant association between cancer and non-cancer families only for females and for those who worked. Conclusions: There was a significant relationship between HRQOL scores and being a family member of a cancer patient. This indicates that the responsibility for care has been extended to the entire family, not only the primary caregiver.

The Quality of Life in COPD Patients according to Gender: Based on the 4th Korea National Health and Nutrition Examination Survey (제4기 국민건강영양조사에 기초한 만성 폐쇄성폐질환자의 성별에 따른 삶의 질 분석)

  • Kang, Kyung Sook;Na, Soon Ok;Yu, Young Beob;Shin, Jun Ho
    • Research in Community and Public Health Nursing
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    • v.26 no.2
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    • pp.61-68
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    • 2015
  • Purpose: In this study, we performed a comparative analysis on the quality of life (QoL) in male and female chronic obstructive pulmonary disease (COPD) patients based on the 4th Korea National Health and Nutrition Examination Survey (KNHANES IV) from 2007 to 2010. Methods: We extracted the socio-demographic and clinical data of 1,218 COPD patients including 874 men and 344 women from the KNHANES IV database. Descriptive statistics and correlation test were used to analyze the data. In order to find factors associated with QoL of COPD patients, we conducted multivariate linear regression analysis. Results: Infrequency analysis, the educational level and income were lower in the female COPD patients than in the male ones. The QoL indexes including mobility, self-care, activities of daily living, discomfort, anxiety, and depression were significantly worse in the female of COPD patients than in the male ones (p<.01).Conclusion: Our study indicates that QoL of female COPD patients should be improved on the educational, economic, and healthcare aspects.

Development and validation of an instrument to measure the health status of healthy but unsatisfied people : Mibyeong index(未病 index) (이상증상 기반 미병 분류도구의 신뢰도 및 타당도 연구)

  • Lee, Youngseop;Baek, Younghwa;Park, Kihyun;Jin, Hee-Jeong;Lee, Siwoo
    • Journal of Society of Preventive Korean Medicine
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    • v.20 no.3
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    • pp.45-53
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    • 2016
  • Objectives : The number of people in Mibyeong state that complain of physical and mental discomfort but without a clear medical diagnosis has rapidly increased, but the conventional medical system is insufficient to care for these people. By establishing an evaluation instrument for Mibyeong state, it will be possible to provide a research base for Mibyeong management system and expand the clinical area of integrative medicine. Methods : Mibyeong Index was designed to measure inconvenience and resilience of subject's complains including four physical symptoms (fatigue, pain, low sleep quality, indigestion) and mental distress include anxiety, anger, depression. A 21-item quality of healthy measure was developed and tested. We used results of a nation-wide stratified sampled adult data in Korea. Results and Conclusions : Mibyeong index had adequate internal consistency, Cronbach's alpha was 0.88 in general population(N=1,110). The correlation between establised quality of life questionnaires (including SF-12 and EQ-D5 VAS) and the Mibyeong index were from 0.468 to 0.493. The national promotion of advanced health for an aging society and original Mibyeong care technology based on traditional Korean medicine can be developed by a self-care system that enhancing health before suffering illness. We expect that this instrument could be contribute to health management of people in Mibyeong state.

Systemic White Blood Cell Count as a Biomarker Associated with Severity of Chronic Obstructive Lung Disease

  • Koo, Hyeon-Kyoung;Kang, Hyung Koo;Song, Pamela;Park, Hye Kyeong;Lee, Sung-Soon;Jung, Hoon
    • Tuberculosis and Respiratory Diseases
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    • v.80 no.3
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    • pp.304-310
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    • 2017
  • Background: Chronic obstructive pulmonary disease (COPD), is a chronic inflammatory disorder. We evaluated whether white blood cell (WBC) count, is associated with the severity of COPD, independent of other inflammatory conditions, such as metabolic syndrome. Methods: The WBC counts were compared between 1227 COPD patients and 8679 non-COPD adults older than 40. The relationships between the WBC count, lung function, and symptoms score in COPD patients, were determined, using general linear regression analyses. Results: The WBC count was negatively associated with forced vital capacity (FVC, L), FVC (% predicted), forced expiry volume in one second ($FEV_1$, L), and $FEV_1$ (% predicted) in COPD patients. Additionally, the WBC count was independently associated with the quality of life measure, by EQ5D-index score. However, this relationship between WBC count, and disease severity, was not significant in current smokers, because of the confounding effect of smoking, on the WBC count. Conclusion: The WBC count is associated with current smoking status and COPD severity, and a risk factor for poor lung function, and quality of life, especially in non-currently smoking COPD patients. The WBC count can be used, as an easily measurable COPD biomarker.

Clinical Research of Korean Medicine and Western Medicine Collaboration Registry for Low Back Pain: A Pilot Study Protocol (요통에 대한 협진 레지스트리 임상연구: 예비 임상연구 프로토콜)

  • Kim, Byung-Jun;Shin, Byung-Cheul;Heo, In;Lim, Kyeong-Tae;Park, In Hwa;Hwang, Eui-Hyoung
    • Journal of Korean Medicine Rehabilitation
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    • v.27 no.3
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    • pp.117-124
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    • 2017
  • Objectives Collaboration medicine means cooperate with western medicine and traditional korean medicine to treat the one disease. In Korea, Interest in collaboration medicine is increasing, But the number of studies is scare. Therefore we will conduct collaboration medicine study for the low back pain. Methods This study composes prospective cohort registry study. If the patients who need collaboration medicine by doctor come, we will ask regist this study. And patient select collaboration treatment group and single treatment group. Total 120 patients will recruit from collaboration pilot project hospitals. Each group patient will observed 4 weeks. Telephone research will conducted after 1 month from the last follow up. During the treatment, patients are treated usual treatment type of each medicine. Primary outcome is NRS and secondary outcomes are EQ-5D and ODI. We will analyze difference of 1 week and 4 week outcome result. Conclusions This study is the first large sample size study effect of collaboration medicine in Korea for low back pain. We check present collaboration system and improve collaboration system. Aim of this study is to find the effectiveness collaboration medicine for low back pain in the real condition. And we expect this pilot study will provide the clinical collaboration information and basis.

A Prospective Observational Study of Herbal Medicines on Depressive Disorder (우울장애 한약치료에 대한 전향적 관찰연구)

  • Kim, Ju Yeon;Kim, Hwan;Lee, Ji-Yoon;Jung, Jin-Hyeong;Yang, Changsop;Lee, Mi-Young;Jung, In Chul
    • Journal of Oriental Neuropsychiatry
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    • v.31 no.2
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    • pp.63-76
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    • 2020
  • Objectives: The purpose of this study was to verify the clinical effects of herbal medicines on patients with depressive disorder. Methods: A prospective observational study on patients with depressive disorder was conducted. The patients were treated with herbal medicines for eight weeks. The Korean Hamilton Depression Rating Scale (K-HDRS) was evaluated as the primary outcome and the Korean Beck's Depression Inventory (K-BDI), Instrument on Pattern Identification for Depression, Korean Symptom Checklist-95 (KSCL-95), Insomnia Severity Index (ISI), Korean State-Trait Anxiety Inventory (STAI-K), Korean State-Trait Anger Expression Inventory (STAXI-K), EuroQol five-dimensional Questionnaire (EQ-5D), Minnesota Multiphasic Personality Inventory-2 (MMPI-2), Heart Rate Variability (HRV) were measured as the secondary outcome. Adverse events were assessed for safety. Results: A total of 35 participants were observed for 12 weeks. The K-HDRS improved significantly in four, eight, and 12 weeks and the K-BDI showed significant differences in four, and eight weeks. There were no significant improvements in other evaluation scales. Gyejibongnyeong-hwan was the most frequently and continuously prescribed, showing significant improvements of K-HDRS after eight weeks of treatment. Conclusions: In our observational study, herbal medicine was effective for relieving the depression of patients with depressive disorder and Gyejibongnyeong-hwan showed the most significant effectiveness.