• Journal of Korean Biological Nursing Science
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• 제17권4호
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• pp.306-314
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• 2015

Purpose: The purpose of this study was to evaluate symptoms, depression and quality of life in colorectal cancer patients who underwent stoma reversal, and to assess the factors related to their quality of life. Methods: A descriptive study was conducted on 125 colorectal cancer patients who underwent stoma reversal in a tertiary hospital in Korea. Data were collected using the Korean versions of the European Organization for Research and Treatment of Cancer-Quality of Life Core 30 and Colorectal Cancer Specific Questionnaire 38 (EORTC QLQ-C30 and CR38), and the Hospital Anxiety-Depression Scale. Data were analyzed using descriptive statistics, t-test, one-way ANOVA, Pearson's correlation, and multiple regression analyses. Results: Participants experienced sexual problems, difficulties in defecation, and nausea/vomiting. About twenty-two percent of the patients were depressed and the mean score for global quality of life was $64.40{\pm}19.43$. The multiple regression showed that social and cognitive functioning, depression, and the location of the anastomosis were the important factors that made contributions to the quality of life in colorectal patients with stoma reversal. Conclusion: Our results suggest that symptom management and emotional support should be incorporated into nursing interventions to improve the quality of life in colorectal patients with stoma reversal.

• 동의생리병리학회지
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• 제28권5호
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• pp.565-570
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• 2014

The purpose of this study is to report a clinical case of a patient with CIPN (Chemotherapy Induced Peripheral Neuropathy) successfully treated with Korean medicine interventions including acupuncture, herbal medicine and moxibustion. The patient is a female with CIPN who was diagnosed with ascending colon cancer and suffering from paresthesia of extremities after chemotherapy of platinum compounds. The patient was treated mainly with electroacupuncture (Ex-LE 10), indirect moxibustion and herbal medicine (Ucha-Shinki-hwan granule). The clinical outcomes were measured by NCI CTCAE grade, EORTC QLQ-C30 (CIPN20) scale and patient's assessment of symptoms. In this case, the NCI CTCAE grade was improved from II to I. The scores of global health status and functional scale in QLQ-C30 were increased and symptom scale was decreased. Especially, this case shows a noticeable decrease in sensory scale in QLQ-CIPN20. In patient's general assessment, the scale was changed from 10 to 5. Korean medical interventions including acupuncture, herbal medicine and moxibustion could potentially be an effective treatment for CIPN if further researches are conducted.

• Asian Pacific Journal of Cancer Prevention
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• 제14권1호
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• pp.435-440
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• 2013

Background: Breast cancer is the leading cause of cancer-related death among women in Malaysia. A diagnosis is very stressful for women, affecting all aspects of their being and quality of life. As such, there is little information on quality of life of women with breast cancer across the different ethnic groups in Malaysia. The purpose of this study was to examine the quality of life in Malay and Chinese women newly diagnosed with breast cancer in Kelantan. Materials and Methods: A descriptive study involved 58 Malays and 15 Chinese women newly diagnosed with breast cancer prior to treatment. Quality of life was measured using the Malay version of the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ-C30) and its breast-specific module (QLQ-BR23). Socio-demographic and clinical data were also collected. All the data were analyzed using SPSS version 20.0. Results: Most of the women were married with at least a secondary education and were in late stages of breast cancer. The Malay women had lower incomes (p=0.046) and more children (p=0.001) when compared to the Chinese women. Generally, both the Malay and Chinese women had good functioning quality-of-life scores [mean score range: 60.3-84.8 (Malays); 65.0-91.1 (Chinese)] and global quality of life [mean score 60.3, SD 22.2 (Malays); mean score 65.0, SD 26.6 (Chinese)]. The Malay women experienced more symptoms such as nausea and vomiting (p=0.002), dyspnoea (p=0.004), constipation (p<0.001) and breast-specific symptoms (p=0.041) when compared to the Chinese. Conclusions: Quality of life was satisfactory in both Malays and Chinese women newly diagnosed with breast cancer in Kelantan. However, Malay women had a lower quality of life due to high general as well as breast-specific symptoms. This study finding underlined the importance of measuring quality of life in the newly diagnosed breast cancer patient, as it will provide a broader picture on how a cancer diagnosis impacts multi-ethnic patients. Once health care professionals understand this, they might then be able to determine how to best support and improve the quality of life of these women during the difficult times of their disease and on-going cancer treatments.

• Asian Pacific Journal of Cancer Prevention
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• 제15권18호
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• pp.7653-7664
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• 2014

Background: Colorectal ranked first among cancers reported in males and ranked second amongst females in Jordan, accounting for 12.7% and 10.5% of cancers in males and females, respectively. Colorectal cancer patients can suffer several consequences after treatment that include pain and fatigue, constipation, stoma complications, sexual problems, appearance and body-image concerns as well as psychological dysfunction. There is no published quantitative data on the health-related quality of life and psychological wellbeing of Jordanian colorectal cancer survivors. Method: This project was a cross-sectional study of colorectal cancer survivors diagnosed in 2009 and 2010. Assessment was performed using the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ-C30), the colorectal cancer specific module (EORTC QLQ-CR 29) and the Hospital Anxiety and Depression Scale (HADS). Data on potential predictors of scores were also collected. Results: A total of 241 subjects completed the study with mean age of $56.7{\pm}13.6$. Males represented 52.3% of study participants. A majority of participants reported good to high overall health; the mean Global health score was $79.74{\pm}23.31$ with only 6.64% of study participants scoring less than 33.3%. The striking result in this study was that none of the study participants participated in a psychosocial support group; only 4 of them (1.7%) were even offered such support. The mean scores for HADS, depression score, and anxiety score were $8.25{\pm}9$, $4.35{\pm}4.9$ and $3.9{\pm}4.6$, respectively. However, 77.1% of study participants were within the normal category for the depression score and 81.7% were within this category for anxiety score; 5.4% of participants had severe anxiety and 5.4% of them had severe depression. Discussion: Patients with colorectal cancer in Jordan have a good quality of life and psychological wellbeing scores when compared with patients from western countries. None of the colorectal cancer patients managed at the Ministry of Health received any formal counselling, or participated in psychological or social support programmes. This highlights the urgent need for a psychosocial support programme, psychological screening and consultations for patients diagnosed with colorectal cancer at the Ministry of Health Hospitals.

• 근관절건강학회지
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• 제24권2호
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• pp.130-139
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• 2017

Purpose: This study was conducted to explore the mediating effect of nutritional status in the relationship between symptom experience and functional status among in patients with lung cancer undergoing chemotherapy. Methods: Subject (N=139) were lung cancer patients visiting the D hospital in B city. Data collection was conducted from May 2016 to February 2017. Seven nutritional status measurement tools, 22 symptom experience tools, and 15 EORTC QLQ-C30 functional scales were used to measure nutritional, symptom, and functional levels. The collected data were analyzed by SPSS / WIN 21.0 using descriptive analysis, Pearson correlation, 3-step regression analysis of Baron and Kenny, and Sobel test. Results: There was a significant positive correlation between symptom experience and nutritional status, a significant negative correlation between symptom experience and functional status, and significant negative correlation between nutritional status and functional status. Symptom experience had direct effect and indirect effects on functional status through nutritional status. Conclusion: For enhancing functional status in lung cancer patients, it is necessary to develop nursing intervention programs to palliate symptoms and improve nutritional status.

• 종양간호연구
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• 제9권2호
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• pp.77-85
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• 2009

Purpose: The purpose of this study was to identify symptom cluster experienced by patients with advanced non-small cell lung cancer (NSCLC) on gefitinib treatment. In addition, this study assessed the patterns in severity of the symptom cluster and differences in quality of life (QOL) and function among subgroups by the severity of symptom cluster. Methods: This study was conducted as a secondary analysis of symptoms of 72 patients from a mother study. Factor analysis was used to identify symptom clusters measured with EORTC QLQ-C30 and LC13 symptom related items. Results: Three symptom clusters were identified: cluster 1 was comprised of fatigue, anorexia and dysphagia; cluster 2 of dyspnea, cough and insomnia; and cluster 3 of pain, constipation and nausea/vomiting. These three symptom clusters were improved one week after gefitinib administration. The group with more severe symptom clusters showed significantly lower QOL and function than the group with less severe symptom clusters. Conclusion: Since symptom clusters experienced by the patients with advanced NSCLC influenced on the QOL and function, it is important for nurses to understand and observe their symptom clusters. In addition, there is an necessity to develop nursing interventions to effectively care patients with the symptom clusters.

• 대한암한의학회지
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• 제25권1호
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• pp.25-39
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• 2020

Objectives : Lung cancer is one of the most common cancer and the leading cause of cancer deaths worldwide. This study aimed to evaluate the role of acupuncture as an adjunctive therapy for lung cancer. Methods : We conducted a systematic review and meta-analysis on the role of acupuncture therapy in lung cancer treatment by electronic and manual searching in ninedatabases, including PubMed, Cochrane library, Embase, Korean databases, and Chinese medical databases. Results : A total of 21 trials were included in the meta-analysis. The study results showed that acupuncture therapy had significant efficacy in immuneregulation, including CD3 andCD4. Further analysis revealed that acupuncture therapy significant improvements in quality of life, including Karnofsky performance status(KPS)score, functional assessment of cancer therapy-lung cancer subscale (FACT-L) and European Organization for the Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ-C30). In addition, the pooled studies also showed that acupuncture therapy reduced cancer pain and chemotherapy-induced nausea and vomiting. Conclusions : Our study provides moderate evidence of the efficacy of the acupuncture therapy in the treatment of lung cancer.

• Asian Pacific Journal of Cancer Prevention
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• 제17권2호
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• pp.723-731
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• 2016

Background: Cancer is a major public health problem in many parts of the world. Gastrointestinal (GI) cancers are responsible for 20% of all cancer-related deaths. In Turkey, stomach cancers account for 8.9%, colon cancer for 6.9%, and pancreatic cancer for 5.9%. This study examined the anxiety-depression levels and the quality of life of patients with GI cancer. Materials and Methods: This descriptive study was carried out on 335 adult patients who had gastrointestinal cancer and who were hospitalized in medical oncology clinics. Data were collected by using hospital anxiety and depression scale, EORTC QLQ C-30 and a patient information form. Results: Patients who were male and secondary school graduates/graduates/postgraduates experienced more functional difficulties. Patients with poor economic status experienced more symptoms. Patient general wellbeing decreased with increase disease duration. The level of functional difficulties decreased with an increasing number of hospital stays. Anxiety scores increased with decreasing age. Both anxiety and depression scores increased with increasing disease duration. Patients who were female, single/widowed/divorced, and literate/elementary school graduates had higher anxiety and depression scores. Life quality decreased with increasing anxiety and depression. Conclusions: Patients should be supported to prevent anxiety and depression, and should be followed up with this in mind.

• 가정∙방문간호학회지
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• 제17권1호
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• pp.45-54
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• 2010

Purpose: This study sought to provide basic information for the establishment of home care nursing system in cancer patients. Methods: Data were collected by the descriptive questionnaires consisting of 42 articles from five fields of nursing services. Patient's symptoms were investigated by the Korean version of EORTC QLQ-C30. Data were analysed using SPSS-PC 12.0. Results: Among the cancer patients (n=182), 40.1% had serious limitations on their usual lives. 74.7% had serious economic burdens. 79.7% agreed strongly with the necessity of home care nursing system, 74.2% were willing to use home care nursing, and 91.2% felt that home care nursing should be mandatory in cancer centers. There was no correlation between the frequency of symptoms or nursing items and the degree of home care nursing requirements. Digestive symptoms, symptoms requiring procedures, and symptoms to meet educational help displayed a high degree of requirement. Conclusion: Home care nursing should be activated for cancer patients as a bridge between hospital-based acute care and community-based chronic care which could increase the quality of care and reduce insurance related payments.

• 종양간호연구
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• 제12권1호
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• pp.12-19
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• 2012

Purpose: To examine the levels of physical activity (PA) and diet quality, socio-demographic and clinical correlates, and identify associations with health-related quality of life (HRQOL) among breast cancer survivors. Methods: The study used a cross-sectional study design. A total of 74 breast cancer survivors who had completed their primary cancer therapy were recruited from a comprehensive cancer center in Korea. Measurements used included the International Physical Activity Questionnaire, the Diet Quality Index, and the EORTC QLQ-C30. Results: Only twenty-six women (35.1%) met the American Cancer Society criteria of weekly PA, while most participants (93.2%) displayed good or excellent diet quality. Those less likely to meet the PA criteria were older women, women who had a lower economic level, and women not receiving anti-hormone therapy. However, there was no significant factor associated with diet quality. Women who met the criteria for PA displayed significantly better global QOL than women who did not meet the criteria. No significant differences were found in HRQOL between women who did and did not meet the diet quality criteria. Conclusion: Nurses should be aware of breast cancer survivors who are older and who have a low economic status when assessing and screening the level of PA to improve HRQOL.