• 한국약용작물학회지
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• 제18권6호
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• pp.429-438
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• 2010

The use of cellulolytic lactic acid bacteria in new method to prepare high nutrition complementary foods was investigated. For the screening of cellulolytic lactic acid bacteria, more than 1,150 bacterial colony were isolated from diluted infant feces samples. A typical strain which appeared the most excellent cellulolytic activities was identified novel acidophilic Enterococcus sp. TO-94 through the results of morphological, biochemical and chemotaxonomic characteristics and 16S rDNA sequencing. The optimal lactic acid fermentation conditions of Omija(Schizandra chinensis Baillon) by Enterococcus sp. TO-94 were as follows: pH and temperature were 3.0 and $37^{\circ}C$, respectively, and fermentation time was 20hrs. The fructose and glucose were major free sugar and the contents were 5.83 and 4.30 mg/g after fermentation, respectively. The contents of lactic acid and acetic acid were 9.84 mg/g and 2.08 mg/g after fermentation, respectively. The vitamin $B_1$, $B_2$, niacin, folic acid and C were major vitamin in the fermented broth, the contents were 1.5~3 times higher than those of initial fermentation time. Also, the contents of polyphenol and anthocyanine were 3.8 and 1.2 times higher than those of initial fermentation time.

• 한국지반공학회:학술대회논문집
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• 한국지반공학회 1992년도 봄 학술발표회 논문집 깊은 기초의 연구와 실무(RESEARCH AND PRACTICE OF DEEP FOUNDATIONS)
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• pp.69-102
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• 1992

말뚝의 지지력 결정은 그 결과로 부터 설계내역이 결정되기 때문에 중요하다. 말뚝의 지지력 결정방법에는 수많은 방법들이 있지만 실무에는 극히 일부분만이 적용되고 있다. 최근 국내 실태조사에 의하면 SPT N 값을 기준으로 한 Meyaerhof공식이 거의 모든 설계에서 적용되고 있으며, 시공중에는 항타공식과 Eoh는 말뚝 재하시험도 실시되고 있다. 본 논문에서는 이들 3가지 방법들을 분석 비교하였다. 분석결과 말뚝재하시험 이외에는 그 신뢰도가 극히 불량하였다. 그리고 말뚝 재하시험 결과의 분석에 있어서, 선단지지력과 주면마찰력을 분리측정하지 않으면 결정적인 오차를 유발할 수 있는 것으로 밝혀졌다. 따라서 선단지지력과 주면마찰력의 분리측정에 의한 말뚝재하시험이 가장 신뢰도가 높은 말뚝지지력 결정방법으로 추천할 수 있다.

• Journal of Korean Neurosurgical Society
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• 제60권1호
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• pp.114-117
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• 2017

A 42-year-old man was admitted to our hospital with complaints of low back pain and intermittent right thigh pain. Twelve weeks before admission, the patient received intradiscal electrothermal therapy (IDET) at a local hospital. The patient still reported low back pain after the procedure that was managed with narcotic analgesics. Follow-up magnetic resonance imaging (MRI) was performed, and his referring physician thought the likely diagnosis was spondylodiscitis at the L4-5 spinal segment with a small epidural abscess. At admission to our department, the patient reported aggravated low back pain. Blood test results, including the erythrocyte sedimentation rate and C-reactive protein levels, were slightly elevated. Biopsy samples of the L4, L5 vertebral bodies and disk were obtained. The material underwent aerobic, anaerobic, fungal, mycobacterial cultures and histologic examination. Results of all cultures were negative. Histologically, necrosis of the bone was evident from the number of empty osteocyte lacunae. In addition, there was no evidence of infection based on biopsy results. No antibiotic treatment was administered on discharge. Repeat computed tomography and MRI performed 12 months after IDET showed a bony defect in the L4 and L5 vertebral bodies, and a decrease in the size of the L4-5 intervertebral disc lesion. We report a case of lumbar vertebral osteonecrosis induced by IDET and discuss etiology and radiologic features.

• 한국안전학회지
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• 제34권4호
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• pp.49-58
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• 2019

There was a difference in recognition of chemical substances according to cognitive level of GHS, knowledge level of organic solvents and each department of workers. they were showed higher recognition of chemical substances by research group, partially group and good group. To identify the relationship between types of job classification(group of department, group of GHS cognitive level and group of organic solvents knowledge level) and the levels of recognition of chemical substances, a total of 153 workers in a small and medium business workplace. Descriptive statistics(SAS ver 9.2)was performed. the results of recognition of chemical substances were analyzed the mean and standard deviation by t-test, and anova, (P=0.05). These results In general, small- and medium-sized workplaces have low levels of GHS awareness and organic solvents knowledge. The perception of chemical substances according to the departments. In general, the demand for chemical substances education was highly suggested regardless of the job type. There was a significant difference in the perception of health, safety and practice according to the level of GHS cognitive, and a high perception in the incomplete group. There was not much difference in average awareness of health, safety and practice according to organic solvents knowledge level, but there was a high perception in good group. It is very important to regularly check the worker's perception of the workplace and identify problems with the work environment and improve the work environment. In addition, each department presents appropriate safety and health education such as chemical process safety, toxicity of chemical substances and human exposure. We also propose a chemical substances assessment and management plan that integrates safety and health.

• Journal of Korean Neurosurgical Society
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• 제30권6호
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• pp.755-760
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• 2001

Objective : To determine the feasibility of translabyrinthine approach in the vestibular schwannoma patients, the authors reviewed eighteen consecutive cases, focusing at their functional outcome and operative complications. Materials and Method : To evaluate the functional outcome, we reviewed preoperative radiological findings such as size of tumors and location of jugular bulb as well as the preoperative neurological status including audiometric analysis and cranial nerve function in 18 patients, diagnosed as vestibular schwannoma. Also the surgical outcome was evaluated according to the functional preservation of facial nerve and incidence of the surgical complication as well as the extent of surgical resection. Results : The age of patients ranged from 21 to 62 years, with a mean of 50 years. Of 18 patients operated in our center by the translabyrinthine approach, wide exposure with total removal of the mass was possible in 16 cases (88.8%). The facial nerve was anatomically preserved in 88.8%. At six-month follow-up, facial nerve function was good(Grade I-II) in 15 patients(83%) and acceptable(I-IV) in all patients. Although the jugular bulb was highly placed is five patients, gross total resection was possible without facial nerve injury in all patients by the translabyrinthine approach. One patient experienced CSF leakage after surgery, but there was no patient with disabling deficit. Conclusion : Use of the translabyrinthine approach for removal of vestibular schwannomas resulted in good anatomical and functional preservation of the facial nerve, with minimal incidence of morbidity and no mortality. In cases of high jugular bulb impacted into mastoid bone, total removal was possible by displacing the jugular bulb with Surgicel cellulose and placement of bone wax.

• Journal of Korean Neurosurgical Society
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• 제30권11호
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• pp.1314-1319
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• 2001

Objects : Because of the nonspecific nature of symptoms in tuberculous spondylitis, a delay in the diagnosis can result in progressive neurologic deficits. The authors evaluate the clinical and the radiological results of the 10 cases of surgically treated tuberculous spondylitis. Clinical materials & Methods : We retrospectively analyzed the medical records of 10 patients with tuberculous spondylitis who were treated between February 1996 and March 2000. Six patients were female, and four were male. Mean age was 43 years old, and mean follow-up period was 20.5 months. All patients were treated with 12 months of antituberculous medication postoperatively, and were followed by complete blood count, ESR, spine X-ray and MRI. Results : The lumbar spine was involved in 5 patients, the thoracic in 4, and the thoracolumbar in one. The infected vertebral bodies were 2.8 in average. The associated lesions were pulmonary tuberculosis in 3 cases, and renal tuberculosis in one. Five patients were treated by anterior debridement and fusion with bone graft using anterior instrumentation, 2 with anterior debridement and fusion with bone graft(Hong Kong procedure only), 1 with Hong Kong procedure with posterior spinal instrumentation, and 2 were managed with posterior debridement and posterior spinal instrumentation. All patients improved after operation, and the average kyphotic angle decreased postoperatively. Postoperatively, one patient had a fistula at the operative site. Conclusion : The debridement and minimal level fusion of motion segment with instrument fixation is one of surgical option for tuberculous spondyltis to preserve the spine motion segment as much as possible. Spine instability and kyphosis were prevented by anterior and posterior spinal instrumentation. But, large number of cases and longer period follow-up study in future will be needed to confirm the long term results.

• Journal of Korean Neurosurgical Society
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• 제29권2호
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• pp.240-248
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• 2000

Objective : Spontaneous intracranial hypotension is a rarely reported syndrome of spontaneous postural headache associated with low CSF pressure and has rarely been demonstrated radiographically or surgically. But recently, it is being recognized with increasing frequency. The purpose of this study was to characterize clinical and imaging features, etiologic factors, and outcome in the spontaneous intracranial hypotension. Patients and Methods : We reviewed our experience with documented cases of spontaneous intracranial hypotension in 5 consecutive patients with orthostatic headaches from April 1998 to April 1999. Results : The mean age was 41 years(from 35 to 49 years). All patients had postural headaches, which were completely alleviated by recumbency position. Nausea, neck pain, horizontal diplopia, photophobia, and blurred vision were noted in some of the patients. Brain MRI showed diffuse pachymeningeal gadolinium enhancement, subdural collections of fluid, and descent of the brain. The opening pressure from lumbar puncture was $4cmH_2O$ or less in three of five patients whereas the opening pressure was within normal range in two patients. All patients underwent radioisotope cisternography and computerized tomographic myelography. On radioisotope cisternography, CSF leakage was suspected at the level of cervical area(1 patient), upper thoracic area(2 patients), mid-thoracic area(1 patient). Computed tomography myelography revealed extraarachnoid accumulation of contrast media(compatible finding with CSF leakage) at the level of cervical or thoracic area. In all patients, the symptoms resolved in response to supportive measures or epidural blood patch(1 patient). Conclusion : Spontaneous spinal CSF leakage is increasingly recognized as a cause of spinal postural headache. Most CSF leaks are located at the cervicothoracic junction or in the thoracic spine and can be demonstrated by variable diagnostic method. The condition is usually self-limiting and its prognosis is typically good.

• 한국안전학회지
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• 제31권5호
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• pp.35-41
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• 2016

Particulate filtering facepiece respirators (PFFR) is one of the most widely used items of personal protective equipments, and a tight fit of the respirators on the wearers is critical for the protection effectiveness. In order to effectively protect the workers through the respirators, it is important to find and evaluate the ways that can be readily applicable at the workplace to improve the fit of the respirators. This study was designed to evaluate effects of mask style (cup or foldable type) and donning training on fit factors (FF) of the respirators, since these are available at various workplace, especially at small business workplace. A total of 40 study subjects, comprised of 30~50s aged male and female workers in metalworking industries, were enrolled in this study. The FF were quantitatively measured before and after training related to the proper donning and use of cup or foldable-type respirators. The pass/fail criterion of FF was set at 100. After the donning training for the cup-type mask, subjects who passed the fit test were increased from 10 to 33. Moreover, the geometric mean (GM) of FF was increased by 340% in subjects who failed the test. In addition, the training effects for the cup-type mask were significant in female and 50s aged subjects. On the other hand, although the GM of FF for the foldable-type mask was also increased after the donning training, the GM of FF for the foldable-type mask and it's increase rate were smaller as compared to the cup-type mask. Furthermore, the differences of the increase rates of the GM of FF in sex and aged of the subjects were not significantly for the foldable-type mask. The multi-distribution of leak points for the foldable-type mask may be one of causes for the less effect of training on the fit of the foldable-type mask. These results imply that the raining on the donning and use of PFFR can enhance the protection effectiveness of cup or foldable-type mask, and that the training effects for the foldable-type mask is less significant than that for the cup-type mask. Therefore, It is recommended that the donning training and fit tests should be conducted before the use of the PFFR, and that efficient tranining programs for the foldable-type mask are required.

• 한국안전학회지
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• 제33권2호
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• pp.52-60
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• 2018

This study compares the differences of the fit factor by the order of wearing preference between Particulate filtering facepiece respirators(PFFR) and glasses when participants wore simultaneously and a survey of physical and visual complaint. Recognition level about fit of respirators was investigated and the educational (before- and after-) effect of the fit factor. When participants wore PFFR and glasses, physical complaints were nose pressure, slipping, nose and ear pressure, ear pressure and rim loosen, the most highly physical complaints were nose pressure. Visual complaints were demister, blurry vision, dizziness, visual field, and lens dirty, the most highly visual complaints were demister. But, there was significant difference in physical complaint such as nose pressure(10.3%), slipping (23.0%), nose and ear pressure(14.3%), and rim loosen(16.2%), visual complaint such as visual field(13.8%) and lens dirty(32.4%). For the recognition of fit of respirators, respirators fitness, leak site, an initial point and an object, faulty factor, recognition level was higher. Fit factor was increased after education of proper wearing of respirator. Change of the fit factor was smaller compared to the normal breathing and after 6 actions in case of after education. Questionnaire consisted of general characteristics and physical/visual complaint, recognition of fit. Complaints were measured after the QNFT with multiple choices. Quantitative fit factor was measured by device and compared the result of (before- and after-) educational effect. Also, we selected to 6 actions (Normal breathing, Deep breathing, Bending over, Turning head side to side, Moving head up and down, Normal breathing) among 8 actions OSHA QNFT (Quantitative Fit testing) protocol to measure the fit factors. The fit factor was higher after the training (p=0.000). Descriptive statistics, paired t-test, and Wilcoxon analysis were performed to describe the result of questionnaire and fit test. (P=0.05) Therefore, it is necessary to investigate the quantitative research such as training program and glasses fitting factor about the wearing of PFFR and glasses simultaneously.

• 대한기계학회논문집B
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• 제34권11호
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• pp.991-998
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• 2010

소듐냉각 고속로 내부기기 배치 변경에 의한 초기냉각 성능변화를 검토하기 위하여 중간열교환기의 수직배치가 다른 3개의 원자로를 대상으로 COMMIX-1AR/P 코드를 활용한 다차원 해석을 수행하였다. 원통좌표계의 중심축을 기준으로 원주방향의 1/4 부분만을 모델링하고 정상상태 및 과도상태 분석을 수행하여 IHX 수직배치 변화가 초기 냉각 특성에 미치는 영향을 분석하였고, DHX를 통한 후기 냉각 모드 개시 시점에 미치는 영향도 분석하였다. 분석 결과 IHX 수직배치 상승은 원자로 풀내부 자연 순환 유량을 증가시켜 초기 냉각과정에서 노심 최고 온도의 급격한 상승을 방지할 수 있으며, 초기냉각 성능을 향상시키기 위한 관성회전차의 가용설계재원의 범위도 확대시킨다. 또한 IHX 수직배치 상승은 후기냉각모드에 큰 영향을 주지 않으면서 초기냉각성능의 향상에 기여할 수 있을 것으로 사료된다.