• The Korean Journal of Emergency Medical Services
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• v.8 no.1
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• pp.19-32
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• 2004

This study was conducted to identify an initial fire station experience of EMT students, so to better understand their' practice experience in fire station. The subjects were 28 EMT students of C department of Emergency Medical technology in C city, who were demonstrating at the fire station in C city. This study was approached by phenomenological method, collected data were analyzed by Colaizzi's method, the results were as a follows. From the protocol, 201 significant statements were organized into 93 formulated meanings. From the formulated meanings, 30 themes were identified, organized into 16 theme clusters, and then 7 categories. EMT students got experienced 'tension' in resulting from new training situation and at the field practice, 'comport and gratitude', in feeling of identity and a bond sympathy with senior EMT, in training environment and heartfelt care, 'stress' from lack of knowledge and skill, difficulties in field practice for 24 hours, in dealing with making interpersonal relationship with patient and staffs and from the insufficiency of instruction, 'confidence feeling' from the participation of field treatment, in improving of learning, in self-esteem of EMT job, 'confusing feeling' of conflict of the path in work, 'disappointment and doubt' by the discrepancy between learning and actuality, and disappointment of actuality, 'feeling of lack' based on the passive attitude. The results of this study are to use as basic data for students attending fire station experience for the first time.

• Journal of Korean Clinical Health Science
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• v.2 no.1
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• pp.25-34
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• 2014

Purpose. The checked of perception for the protection of personal medical information of EMT student and Nursing student. Methods. Nursing students and EMT students 200 questionnaires were collected and Frequency analysis, Chi-square test, one-way ANOVA was performed for using the Windows SPSS(ver. 12.0). Results. Most of the subjects were aware of the protection law of personal information and Infringement of the privacy of personal information will be exposed. also, Education is needed privacy(EMT students $3.84{\pm}0.96$, Nursing students $3.73{\pm}0.99$). EMT($3.99{\pm}1.00$) and Nursing($4.07{\pm}0.94$)students due to exposure to both the patient's personal information privacy was violated would get recognized. Exposure to the computerization of information privacy will be exploited in other agencies(EMT students $3.78{\pm}0.88$, Nursing students $3.95{\pm}0.94$) was called. Conclusions. For the protection of personal health information, education needs to be expanded.

• The Korean Journal of Emergency Medical Services
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• v.11 no.2
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• pp.5-17
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• 2007

Purpose: The purpose of this study was to supply basic data for a health promoting program and to elevate the level of it by examining whether EMT-P Students' health promoting behaviors were related to health percetion, health concept, health status, self-esteem, perceived benefits of action, perceived barriers of action, perceived self-efficacy, activity-related affect, social support, preference, prior related behavior, and a plan for action. Method: Subjects were 116 EMT-P Students in K city. Data collection method was a structured questionnaire. Data was analyzed using descriptive statistics, t-test, ANOVA, Pearson's correlation analysis, and stepwise multiple regression. Result: The most powerful predictor was prjor related behavior(28.8%). Altogether prjor related behavior, health status, perceived barriers of action, a plan for action were proven to account for 44.6% of health promoting behaviors of EMT-P Students. Conclusion: It suggested that prjor related behavior, health status, perceived barriers of action, a plan for action should be considered when developing a EMT-P Students' health promoting program.

• Tuberculosis and Respiratory Diseases
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• v.70 no.6
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• pp.462-473
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• 2011

Background: Smoking is a risk factor for idiopathic pulmonary fibrosis (IPF), but the mechanism of the association remains obscure. There is evidence demonstrating that plasminogen activator inhibitor-1 (PAI-1) is involved in the progression of pulmonary fibrosis. This study was to determine whether the administration of small interfering RNA (siRNA) targeting PAI-1 or PAI-1 inhibitor to the cigarette smoking extract (CSE)-exposed rat alveolar type II epithelial cells (ATII cells) limits the epithelial-mesenchymal transition (EMT). Methods: ATII cells were isolated from lung of SD-rat using percoll gradient method and cultured with 5% CSE. The EMT was determined from the ATII cells by measuring the real-time RT PCR and western blotting after the PAI-1 siRNA transfection to the cells and after administration of tiplaxtinin, an inhibitor of PAI-1. The effect of PAI-1 inhibitor was also evaluated in the bleomycin-induced rats. Results: PAI-1 was overexpressed in the smoking exposed ATII cells and was directly associated with EMT. The EMT from the ATII cells was suppressed by PAI-1 siRNA transfection or administration of tiplaxtinin. Signaling pathways for EMT by smoking extract were through the phosphorylation of SMAD2 and ERK1/2, and finally Snail expression. Tiplaxtinin also suppressed the pulmonary fibrosis and PAI-1 expression in the bleomycin-induced rats. Conclusion: Our data shows that CSE induces rat ATII cells to undergo EMT by PAI-1 via SMAD2-ERK1/2-Snail activation. This suppression of EMT by PAI-1 siRNA transfection or PAI-1 inhibitor in primary type II alveolar epithelial cells might be involved in the attenuation of bleomycin-induced pulmonary fibrosis in rats.

• Journal of the Korea Society of Computer and Information
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• v.27 no.2
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• pp.135-144
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• 2022

Electromagnetic topology (EMT) technique is a method to analyze each component of the electromagnetic propagation environment and combine them in the form of a network in order to effectively model the complex propagation environment. In a typical commercial communication channel model, since the propagation environment is complex and difficult to predict, a probabilistic propagation channel model that utilizes an average solution, although with low accuracy, is used. However, modeling techniques using EMT technique are considered for application of propagation and coupling analysis of threat electromagnetic waves such as electromagnetic pulses, radio wave models used in electronic warfare, local communication channel models used in 5G and 6G communications that require relatively high accuracy electromagnetic wave propagation characteristics. This paper describes the effective implementation method, algorithm, and program implementation of the electromagnetic topology (EMT) method analyzed in the frequency domain. Also, a method of deriving a response in the time domain to an arbitrary applied signal source with respect to the EMT analysis result in the frequency domain will be discussed.

• 대한예방의학회:학술대회논문집
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• 1995.10a
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• pp.321-322
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• 1995

• Korean Journal of Clinical Laboratory Science
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• v.50 no.3
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• pp.337-344
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• 2018

Hepatocellular carcinoma (HCC), a major type of hepatoma, is associated with high recurrence and mortality because of its uncontrolled metastatic feature. Silymarin is a polyphenolic flavonoid from Silybum marianun (milk thistle) and exhibits anti-carcinogenic activity through modulation of the epithelial-mesenchymal transition (EMT) in several cancer cells. In this study, the inhibitory mechanism of silymarin against migration and invasion was investigated in the Huh7 HCC cell line. Wound healing and in vitro invasion assays were conducted to examine the effects of silymarin on migration and invasion. Western blot analysis was also applied to evaluate the inhibitory effects of silymarin on the EMT-related genes and their upstream signaling molecules. Silymarin inhibited the migratory and invasive activities of Huh7 cells. In addition, silymarin attenuated the protein expression levels of vimentin and matrix metalloproteinase (MMP)-9 as well as their transcription factors, Snail, and nuclear factor $(NF)-{\kappa}B$, while the expression of E-cadherin was increased by the silymarin treatment. Among the upstream signaling molecules, the phosphorylation of Akt was inhibited by the silymarin treatment, which was confirmed by the selective inhibitor, LY294002. Consequently, silymarin inhibited the invasive and migratory activities in Huh7 cells through the modulation of EMT-related gene expression by the PI3K/Akt signaling pathway, which may have potential as a chemopreventive agent against HCC metastasis.

• The Korean Journal of Emergency Medical Services
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• v.13 no.1
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• pp.49-60
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• 2009

The purpose of this study was to investigate the creativity and problem-solving of EMT students in Gwangju Metropolitan City. Data was collected by self-reported questionnaire from 106 EMT students from December 1, to December 20, 2008, Data collected were analyzed by technical statistics and correlation analysis using $SPSS/PC^+$ 12.0 program, The results were as follows : 1. The subjects were 49 males (46%) and 57 females (54%). 2. According to gender characteristics and creativity of the subjects, there were not significant differences(t = 1.02, p = .312). To gender characteristics and problem-solving of the subjects, male were higher grade more than female and there were significant differences(t = 2.04, p = .044). 3. According to age characteristics and creativity of the subjects, there were not significant differences(F = 8.73, p = .421). To age characteristics and problem-solving of the subjects, there were not significant differences(F = 2.314, p = .104). 4. There was positive correlation between creativity and problem-solving(r = .489, p = .000). Therefore, these findings showed that more studies needed about creativity and problem-solving on EMT students and creative problem-solving programs be started for these EMT students in order to development their creativity and problem-solving.

• Journal of dental hygiene science
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• v.17 no.5
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• pp.433-438
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• 2017

Relative to its incidence, oral cancer has serious negative social effects. The exact causes of oral cancer have not been clarified, but many studies have implicated smoking and drinking. However, the fundamental mechanism of oral cancer causation has yet to be elucidated. Lysophosphatidic acid (LPA) augments epithelial mesenchymal transition (EMT) and development of various cancer cells. However, a detailed mechanistic explanation for LPA-induced EMT and the effects of EMT-promoting conditions on oral squamous cell carcinoma development remain elusive. In the present study, a quantitative reverse transcription polymerase chain reaction was used to analyze TWIST1, Slug, E-cadherin, and glyceraldehyde-3-phosphate dehydrogenase (GAPDH) transcript expression. Immunoblotting was used to analyze TWIST1, Slug, E-cadherin, and GAPDH protein expression. siRNAs were used to silence TWIST1 and Slug transcript expression. A matrigel-coated in vitro invasion insert was used to analyze oral cancer cell invasion. The results of the present study show that the expression levels of TWIST1 and Slug, which are EMT factors, were increased by LPA treatment in YD-10B oral squamous cell carcinoma. Conversely, E-cadherin expression was significantly reduced. In addition, transfection of the cells with TWIST1 and Slug siRNA strongly inhibited LPA-induced oral cancer cell invasion. The present study shows that TWIST1 and Slug mediate LPA-induced oral cancer cell EMT and invasiveness. The present study confirmed the mechanism by which LPA promotes oral cancer cell development, with TWIST1 and Slug providing novel biomarkers and promising therapeutic targets for oral cancer cell development.

• The Korean Journal of Emergency Medical Services
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• v.15 no.1
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• pp.89-99
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• 2011

Purpose : This study was performed to examine the euthanasia attitude of EMT students. Method : The results were based on the revised questionnaires on euthanasia. Total 155 students filled out the questionnaires in September 17-18, 2009. Data were analyzed using SPSS 14.0 in terms of means, $x^2-test$, mean, standard deviation, and one way ANOVA. Results : The euthanasia attitude was no statistically significant difference between three groups. In the area of quality of life, there were no statistically significant difference between three groups. In the area of life respect, there were no statistically significant difference between three groups. In the area of medical ethics, there were statistically significant difference between three groups. In the area of client right, there were no statistically significant difference between three groups. Conclusion : This results showed that education of euthanasia attitude must be instructed to EMT students. It is necessary to make a further development euthanasia program of EMT.