• Title/Summary/Keyword: EGFR Tyrosine Kinase Inhibitor 324674

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Systemic Nocardiosis Mimicking Disease Flare-up after Discontinuation of Gefitinib in a Patient with EGFR-Mutant Lung Cancer

  • Choi, Mihong;Lee, Youngjoo;Hwang, Sang Hyun;Lee, Jin Soo
    • Tuberculosis and Respiratory Diseases
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    • v.77 no.6
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    • pp.271-273
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    • 2014
  • Disease flare-up after discontinuing epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) has been considered as a critical issue in lung cancer patients who have experienced radiologic progression after showing initial durable response. This is a case of systemic nocardiosis that occurred after chronic steroid use for radionecrosis from stereotactic radiosurgery. It was initially thought as a disease flare-up after stopping EGFR-TKI.