• Journal of Biomedical Engineering Research
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• v.15 no.2
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• pp.151-158
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• 1994

It has been shown that many of physiological systems have nonlinear dynamics. The evidences of these nonlinear behaviors make us analyze physiological systems in the new viewpoint. And, some of these nonlinear dynamics can be represented by chaotic behaviors, which is studied by several methods-correlation dimension, return map, power spectrum analysis, etc. This study is on the analysis of nonlinear characteristics of ECG. After data have been acquired from 20 children (10-13 years old), and 30 students (20-24 years old). We have calculated parameters HR, PR, VAT, TD, TRD, TPD from data, and estimated correlation dimension, return map, power spectrum, time series. Results show the nonlinear and chaotic characteristics of ECG.

• Korean Journal of Radiology
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• v.22 no.7
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• pp.1034-1043
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• 2021

Objective: The purpose of this meta-analysis was to investigate the pooled agreements of the coronary artery calcium (CAC) severities assessed by electrocardiogram (ECG)-gated and non-ECG-gated CT and evaluate the impact of the scan parameters. Materials and Methods: PubMed, EMBASE, and the Cochrane library were systematically searched. A modified Quality Assessment of Diagnostic Accuracy Studies-2 tool was used to evaluate the quality of the studies. Meta-analytic methods were utilized to determine the pooled weighted bias, limits of agreement (LOA), and the correlation coefficient of the CAC scores or the weighted kappa for the categorization of the CAC severities detected by the two modalities. The heterogeneity among the studies was also assessed. Subgroup analyses were performed based on factors that could affect the measurement of the CAC score and severity: slice thickness, reconstruction kernel, and radiation dose for non-ECG-gated CT. Results: A total of 4000 patients from 16 studies were included. The pooled bias was 62.60, 95% LOA were -36.19 to 161.40, and the pooled correlation coefficient was 0.94 (95% confidence interval [CI] = 0.89-0.97) for the CAC score. The pooled weighted kappa of the CAC severity was 0.85 (95% CI = 0.79-0.91). Heterogeneity was observed in the studies (I² > 50%, p < 0.1). In the subgroup analysis, the agreement between the CAC categorizations was better when the two CT examinations had reconstructions based on the same slice thickness and kernel. Conclusion: The pooled agreement of the CAC severities assessed by the ECG-gated and non-ECG-gated CT was excellent; however, it was significantly affected by scan parameters, such as slice thickness and the reconstruction kernel.

• Journal of Biomedical Engineering Research
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• v.19 no.3
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• pp.251-260
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• 1998

The Holter monitoring system is a widely used noninvasive diagnostic tool for ambulatory patient who may be at risk from latent life-threatening cardiac abnormalities. In this paper, we design a high performance intelligent holter monitoring system which is characterized by the small-sized and the low-power consumption. The system hardware consists of one-chip microcontroller(68HC11E9), ECG preprocessing circuit, and flash memory card. ECG preprocessing circuit is made of ECG preamplifier with gain of 250, 500 and 1000, the bandpass filter with bandwidth of 0.05-100Hz, the auto-balancing circuit and the saturation-calibrating circuit to eliminate baseline wandering, ECG signal sampled at 240 samples/sec is converted to the digital signal. We use a linear recursive filter and preprocessing algorithm to detect the ECG parameters which are QRS complex, and Q-R-T points, ST-level, HR, QT interval. The long-term acquired ECG signals and diagnostic parameters are compressed by the MFan(Modified Fan) and the delta modulation method. To easily interface with the PC based analyzer program which is operated in DOS and Windows, the compressed data, that are compatible to FFS(flash file system) format, are stored at the flash memory card with SBF(symmetric block format).

• Proceedings of the KOSOMBE Conference
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• v.1996 no.11
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• pp.118-121
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• 1996

This paper describes ECG signal labeling based on Fuzzy clustering, which is necessary at automated ECG diagnosis. The NPPA(Non parametric partitioning algorithm) compares the correlations of wave forms, which tends to recognize the same wave forms as different when the wave forms have a little morphological variation. We propose to apply Fuzzy clustering to ECG QRS Complex labeling, which prevents the errors to mistake by using If-then comparision. The process is divided into two parts. The first part is a parameters extraction process from ECG signal, which is composed of filtering, QRS detection by mapping to a phase space by time delay coordinates and generation of characteristic vectors. The second is fuzzy clustering by FCM(Fuzzy c-means), which is composed of a clustering, an assessment of cluster validity and labeling.

• Korean Circulation Journal
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• v.54 no.3
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• pp.140-153
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• 2024

Background and Objectives: Although a single-lead electrocardiogram (ECG) patch may provide advantages for detecting arrhythmias in outpatient settings owing to user convenience, its comparative effectiveness for real-time telemonitoring in inpatient settings remains unclear. We aimed to compare a novel telemonitoring system using a single-lead ECG patch with a conventional telemonitoring system in an inpatient setting. Methods: This was a single-center, prospective cohort study. Patients admitted to the cardiology unit for arrhythmia treatment who required a wireless ECG telemonitoring system were enrolled. A single-lead ECG patch and conventional telemetry were applied simultaneously in hospitalized patients for over 24 hours for real-time telemonitoring. The basic ECG parameters, arrhythmia episodes, and signal loss or noise were compared between the 2 systems. Results: Eighty participants (mean age 62±10 years, 76.3% male) were enrolled. The three most common indications for ECG telemonitoring were atrial fibrillation (66.3%), sick sinus syndrome (12.5%), and atrioventricular block (10.0%). The intra-class correlation coefficients for detecting the number of total beats, atrial and ventricular premature complexes, maximal, average, and minimal heart rates, and pauses were all over 0.9 with p values for reliability <0.001. Compared to a conventional system, a novel system demonstrated significantly lower signal noise (median 0.3% [0.1-1.6%] vs. 2.4% [1.4-3.7%], p<0.001) and fewer episodes of signal loss (median 22 [2-53] vs. 64 [22-112] episodes, p=0.002). Conclusions: The novel telemonitoring system using a single-lead ECG patch offers performance comparable to that of a conventional system while significantly reducing signal loss and noise.

• Journal of Biomedical Engineering Research
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• v.41 no.2
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• pp.107-119
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• 2020

The deep neural networks (DNN) that can replicate the behavior of the human expert who recognizes the characteristics of ECG waveform have been developed and studied to analyze ECG. However, although the existing DNNs can not provide the explanations for their decisions, those trials have attempted to determine whether patients have certain diseases or not and those decisions could not be accepted because of the absence of relating theoretical basis. In addition, these DNNs required a lot of training data to obtain sufficient accuracy in spite of the difficulty in the acquisition of relating clinical data. In this study, a small-sized continuous data processing DNN (C-DNN) was suggested to determine the simple characteristics of ECG wave that were not required additional explanations about its decisions and the C-DNN can be easily trained with small training data. Although it can analyze small input data that was selected in narrow region on whole ECG, it can continuously scan all ECG data and find important points such as start and end points of P, QRS and T waves within a short time. The star and end points of ECG waves determined by the C-DNNs were compared with the results performed by human experts to estimate the accuracies of the C-DNNs. The C-DNN has 150 inputs, 51 outputs, two hidden layers and one output layer. To find the start and end points, two C-DNNs were trained through deep learning technology and applied to a parameter acquisition algorithms. 12 lead ECG data measured in four patients and obtained through PhysioNet was processed to make training data by human experts. The accuracy of the C-DNNs were evaluated with extra data that were not used at deep learning by comparing the results between C-DNNs and human experts. The averages of the time differences between the C-DNNs and experts were 0.1 msec and 13.5 msec respectively and those standard deviations were 17.6 msec and 15.7 msec. The final step combining the results of C-DNN through the waveforms of 12 leads was successfully determined all 33 waves without error that the time differences of human experts decision were over 20 msec. The reliable decision of the ECG wave's start and end points benefits the acquisition of accurate ECG parameters such as the wave lengths, amplitudes and intervals of P, QRS and T waves.

• Proceedings of the KOSOMBE Conference
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• v.1995 no.11
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• pp.193-196
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• 1995

An algorithm using topological mapping has been developed for a real-time detection of the QRS complexes of ECG signals. As a measurement of QRS complex energy, we used topological mapping from one dimensional sampled ECG signals to two dimensional vectors. These vectors are reconstructed with the sampled ECG signals and the delayed ones. In this method, the detection rates of CRS complex vary with the parameters such as R-R interval average and peak detection threshold coefficient. We use mean, median, and iterative method to determint R-R interval average and peak estimation. We experiment on various value of search back coefficient and peak detection threshold coefficient to find optimal rule.

• Journal of the Korean Institute of Telematics and Electronics
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• v.26 no.8
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• pp.1217-1226
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• 1989

This paper describes a design of hardware system for real time automatic diagnosis of ECG arrhythmia based on pipeline processor consisting of three microcomputer. ECG data is acquisited by 12 bit A/D converter with hardware QRS triggered detector. Four diagnostic parameters-heart rate, morpholigy, axis, and ST segment-are used for the classification and the diagnosis of arrhythmia. The functions of the main CPU were distributed and processed with three microcomputers. Therefore the effective data process and the real time process using microcomputer can be obtained. The interconnection structure consisting of two common memory unit is designed to decrease the delay time caused by data transfer between processors and be which the delay time can be taken 1% of one clock period.

• Proceedings of the KOSOMBE Conference
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• v.1992 no.11
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• pp.47-50
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• 1992

This paper describes pattern classification algorithm of ECG using back-propagation neural network. We presents new feature extractor using second order approximating function as the input signals of neural network. We use 9 significant parameters which were extracted by feature extractor. 5 most characterized ECG signal pattern is classified accurately by neural network. We use AHA database to evaluate the performance ol the proposed pattern classification algorithm.

• Proceedings of the KIEE Conference
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• 1988.07a
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• pp.731-733
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• 1988

This paper describes a design of hardware system for real time automatic diagnosis of ECG arrhythmia based on pipeline processor consisting of the three microcomputer. ECG data is acquisited by 12 bit A/D converter with hardware QRS triggered detector. Four diagnostic parameters - heart rate, morphology, axis, and ST segment - are used for the classification and the diagnosis of arrhythmia. The functions of the main CPU were distributed and processed with three microcomputers. There-fore the effective data process and the real time process using microcomputer can be obtained. The interconnection structure consisting of two common memory units is designed to decrease the delay time caused by data transfer between processors and by which the delay time can be taken 1 % of one clock period.