• 대한의용생체공학회:의공학회지
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• 제25권6호
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• pp.623-628
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• 2004

본 논문에서는 원적외선 온열효과가 자율 신경계에 미치는 영향을 심박변동(HRV)을 이용하여 평가 하였다. 측정된 심박변동신호를 FFT 의한 전력스펙트럼을 구함으로써 자율 신경계의 반응 특성을 고찰하고 Poincare plot 분석 방법을 이용하여 결과를 비교 분석하였다. 실험을 통해 심박변동 신호분석해보면 원적외선 온열에 노출되기 전에 비해 노출된 후에 매우 복잡한 모습임을 관찰 할 수 있었는데 이것은 자율신경계가 관여하는 심혈관계 제어 메커니즘이 원적외선 온열에 노출되기 전보다 노출된 후에 더욱 복잡함을 반영하는 것으로 분석된다.

• 대한전자공학회:학술대회논문집
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• 대한전자공학회 2005년도 추계종합학술대회
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• pp.493-496
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• 2005

For home healthcare, the unconstrained measurement of physiological signal is highly required to avoid the inconvenience of users. The recording and analysis of the fundamental parameters during sleep like respiration and heart beat provide valuable information on his/her healthcare. Using the air mattress sensor system, the respiration and heart beat movements can be measured without any harness or sensor on the subject's body. The differential measurement technique between two air cells is adopted to enhance the sensitivity. The balancing tube between two air cells is used to increase the robustness against postural changes during the measurement period. The meaningful frequency range could be selected by the pneumatic filter with balancing tube. ECG (Electrocardiography) and respiration sensor (plethysmography) were measured for comparison with the signal from air mattress. To extract the heart beat information from air pressure sensor, digital signal processing technique was used. The accuracy for breathing interval and heart beat monitoring was acceptable. It shows the potentials of air mattress sensor system to be the unconstrained home sleep monitoring system.

• 대한의용생체공학회:의공학회지
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• 제18권1호
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• pp.37-44
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• 1997

In this paper, the power spectral analysis of heart rate variability(HRV) was performed to evaluate effects of orthostatic stress with head-up tiIt on autonomic nervous system(ANS) for 25 healthy male subjects(age : 24 $\pm$ 5 yr.) and a new method was proposed to assess the autonomic balance. The ECG and respiration signals were recorded at tiIt angles of $0^{\circ}$, $45^{\circ}$, $90^{\circ}$and $0^{\circ}$ successively for 10 minutes per each stage under the condition of frequency controlled respiration(0.25Hz). Heat rate(HR) gradually increased ils the angle increased Similarly, according to the increment of angle, normalized low frequency component(0.05-0.15Hz) gradually increased, whereas normalized high frequency component (0.20-0.30Hz) was reduce4 From these results it is speculated that orthostatic stress head-up tiLt, results in the prevalence of sympathetic tone in autonomic balance with the increment of sympathetic tone and the decrement of parasympathetic tone, which seems to meanthat autonomic nervous system plays a major role in compensating for disturbances of cardiovascular system due to it.

• Journal of Electrical Engineering and Technology
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• 제10권1호
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• pp.364-371
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• 2015

In this study, we developed a feasible structure of a textile-based inductive sensor using a machine embroidery method, and applied it to a non-contact type vital sign sensing device based on the principle of magnetic-induced conductivity. The mechanical heart activity signals acquired through the inductive sensor embroidered with conductive textile on fabric were compared with the Lead II ECG signals and with respiration signals, which were simultaneously measured in every case with five subjects. The analysis result showed that the locations of the R-peak in the ECG signal were highly associated with sharp peaks in the signals obtained through the textile-based inductive sensor (r=0.9681). Based on the results, we determined the feasibility of the developed textile-based inductive sensor as a measurement device for the heart rate and respiration characteristics.

• 전기학회논문지
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• 제61권6호
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• pp.891-898
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• 2012

The study for the passenger's comfortableness of vehicles and the arousal of car drivers has been done widely. On the other hand, there are few studies for the locomotive engineers. Human error means that the mistakes made by human, recently it receives attention in the field of safety engineering and human engineering. Comparing the operating condition of train with car, because of the simplification of the visual stimulus, the arousal level on the train goes down easily. The arousal level down makes judgement down, the accident risk from human error is getting bigger. In this study, we measured bio-signals(ECG, EDA, PPG, respiration and EEG) from 6 locomotive engineers to evaluate their arousal state while they operated the train. Also we recorded the 3 axes acceleration signal showing the vibration state of train. Also, the existence of tunnels were simultaneously measured. At the station section where the train speed goes down, the size of vector's sum decreases because of reduced vibration. Beta component in EEG tends to increase at the entering point of each station and tunnel. It is due to the arousal reaction and tension growth. The mean SCR(skin conductance response) was more increased in neutral section. As the button control movement (body movement) increases in the neutral section, it is appeared that SCR increase. RR interval tends to gradually increase during train operation for 1 hour 40 minutes. However, It tends to sharply decrease at the stop station because strong concentration needed to stop train on the exact point. The engineer's arousal reaction can be checked through analysing the bio-signal change during train operation. Therefore, if this analysing result is adopted to the sleepiness prevention caution system, it will be useful for the safety train operation.

• 대한인간공학회지
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• 제25권4호
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• pp.129-135
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• 2006

he purpose of this study is to measure bio-signal to investigate the driver's physiological response change under real situation using train simulator. The train simulator used in this study is KTX model and according to changes of driving situation, The bio-signal controlled by autonomic nervous system, such as GSR(Galvanic Skin Response), SpO2(Saturation percent O2), HR(Heart Rate), ECG(Electrocardiograph), EEG(Electroencephagram) and movement and response of eye were measured. Statistically significant difference in bio-signal data and eye movement activity pattern were investigated under several different driving speeds using analysis of variance (p<0.05). The GSR and HR value measured in average and mission speed operation is higher than in high-speed operation. β wave of EEG in average speed operation become more activated than in high speed operation. In accordance with a characteristic of rail vehicle, movement and response of eye in high-speed operation requiring relatively simple maneuver become less activated than in either average or mission speed operations. Conclusively, due to more careful driving controls in average and mission speed operation are required than in high-speed operation, level of mental and physical stresses of train driver was increased and observed through changes of bio-signal and eye movement measured in this study.

• 디지털융복합연구
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• 제18권8호
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• pp.231-242
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• 2020

연구의 목적은 가정에서 안정 시 인체의 생리적 활력 정보를 센서와 ICT 정보 기술을 통해 연속적으로 수집하는 시스템과 수집된 정보를 이용하여 당뇨병증 유무를 예측하는 인공신경망 기계학습 방법과 필수적인 기본 변수 값을 제시하였다. 연구 방법은 정상인(DM-) 20명과 당뇨병(DM+) 15명을 대상으로 BCG와 ECG 센서의 심박수 측정값의 상관 관계를 분석하였으며 상관 계수는 R²=0.959이다. Artificial Neural Network(ANN) 기계학습 프로그램을 이용하여 당뇨병증 예측 가능성을 확인하였고 입력 변수는 심박변이도의 시계열정보와 심박수, 심박변이도, 호흡율, 박동량 정보, 최저혈압, 최고혈압, 년령, 성별이며 ANN 기계학습 예측 정확도는 99.53%이다. 그리고 향후 ANN 기계학습 방법을 활용하여 BMI 정보를 이용한 당뇨예측 모델, 심장 기능 장애 예측 모델, 수면장애 분석 모델 등의 계속적인 연구가 필요하다.

• Archives of Pharmacal Research
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• 제29권11호
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• pp.977-983
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• 2006

The objective was to devise an animal model of myocardial infarction (MI) against which cardioprotective drugs might be tested. We describe the effects of nimesulide, a COX experience with development and validation of such a model. The rabbit was chosen in preference to rodents because its heart and cardiac circulation more closely resemble those of human. Thus, the cardiovascular system of anaesthetized male rabbits, 1 to 1.5 kg (n=11), was stressed by a single bolus intravenous injection of isoprenaline (ISP), 65 mg/kg. The effects of the injection were followed for sixteen days and were evaluated in four ways: 1) measurements of creatinine kinase isozyme and troponin-I (TPI) in serum 2) Electrocardiographic (ECG) changes (ST elevation and Q wave development) 3) Cardiac histopathology observed in tissue sections of the isolated of the heart. The histopathological analysis showed that rabbit heart on 2nd day after ISP injection showed changes of coagulation necrosis. Day 4 total coagulation with the loss of nuclear and striation associated with heavy interstitial infiltrate of neutrophils was found. Day 8 after infarction showed collagen deposition with capillary channels in between the remaining islands of myocytes in the infarcted area. On the 16th day scarring was complete. Coronary perfusion rates (CPR) and heart rate (HR) of the infarcted and nimesulide (a COX-2 inhibitor) treated rabbits displayed significant improvement (n=11) on each corresponding day after infarction as compared to the infarcted and saline treated rabbits (P<0.05). All four indices revealed similarities with effects commonly associated with MI in humans.

• 대한전자공학회:학술대회논문집
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• 대한전자공학회 2003년도 하계종합학술대회 논문집 V
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• pp.2883-2886
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• 2003

좋은 발성을 위하여 음성이 만들어지려면, 뇌의 언어중추의 명령에 의하여 신경망을 통하여 ‘호흡기관(폐와 흉곽. 호흡관련 근육들)’과 ‘발성기관(주로 후두 즉 성대)’ 그리고 ‘조음, 공명기관(인두, 구강 및 비강)’의 근육들이 유기적으로 작용하여야 한다. 이런 협력 체제에 문제가 생기면, 다양한 종류의 질환이 유발될 수 있다[1,2]. 현재 임상에서 음성 분석을 위해 사용되는 시스템은 대부분 성대의 진동을 측정하기 위해 stroboscopy, 전기성문파형검법 (EGG, electroglottography), 후두근전도 중의 한 방법과 음성 분석을 위한 분석 프로그램으로 구성되어 있다. 그러나, 발성은 호흡과 매우 밀접한 관계가 있어 음성, 성대의 진동, 호흡 관계를 종합적으로 관찰할 필요가 있다. 본 연구에서는 발성 시 성대 점막의 접촉 양상은 ECG 로 측정하며, 발성의 주 에너지원이 되는 호흡의 변화를 2 channel 인덕턴스 호흡감시 장치(RIP: repiratory inductive plethymography)를 이용하여 흉곽의 움직임과 상 복강의 움직임에 대하여 측정하며, 발성되는 음성은 마이크로폰을 통하여 측정하는 ‘EGG, 음성, 호흡 통합검사 장치’를 개발하였다.

• 감성과학
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• 제1권1호
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• pp.93-103
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• 1998

In this paper, we present change of human sensiblity when the 26 healthy female subjects were exposed with visual picture stimulus. We used Intermational Affective Picture System as the visual stimulus. The methods are AutoRegressive(AR) spectrum which is a linear method and Return Map which is a nonlinear mithod. SR spectrum may variability(HRV). The LF/HF of HRV and the variation of Return Map were analyzed from ECG signal of the female subjects. Return Map of RR intervals were analyzed by computiong the variation. When the subjets were stimulated by the pleasant pictures, LF/HF and variation were decreased compared with unpleasant stimulus, We may obtain good parameters for the measurement of the change of human sensibility for the visual picture stimulus.