• 대한화학회지
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• 제42권1호
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• pp.99-101
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• 1998

• 무역상무연구
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• 제13권
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• pp.699-733
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• 2000

This article analyzes the state-of-play of WTO dispute settlement for first four and a half years. Remarkable points found on this analysis are as follows: First, the Quad consisting of the United States, the European Community (EC), Canada and Japan has participated in the WTO dispute settlement mechanism more frequently than any other WTO member. Second, among developing country members some leading countries such as Korea, Brazil and India have relied actively upon the mechanism to claim and defend their rights and obligations under the WTO rules. Third, bilateral dispute settlements generally have been preferred to multilateral dispute settlements by the panel or Appellate Body. Fourth, observation of the Appellate Body proceedings well shows WTO members' strategy to use every process available to them. Fifth, the provisions of GATT 1994 have been most frequently invoked by the members. GATS and TRIPS Agreement disputes are mainly involved in developed countries, in particular the U.S. and the EC. Sixth, very high winning ratio in the panel and Appellate Body process indicates that complaining parties review the possibility to get favorable rulings even before referring to the Dispute Settlement Body (DSB) and prepare for the case very thoroughly. Seventh, roughly speaking, disputes were settled within two or three years. Therefore, seeking bilateral dispute settlement can be more advantageous to a complaining party than referring to a panel or an arbitrator because of low costs and short time period in dispute settlement. Finally, the DSB approved retaliatory actions for winning complaining parties against the defending parties who had rejected implementation of its rulings and recommendations. In conclusion, it can be said that the WTO dispute settlement mechanism has been operated very successfully for the first four and a half years. It is hoped that continued study on state-of-play of WTO dispute settlement mechanism will be contributory to improved national interest of Korea.

• 한국데이타베이스학회:학술대회논문집
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• 한국데이타베이스학회 1999년도 춘계공동학술대회: 지식경영과 지식공학
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• pp.353-359
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• 1999

We present a matrix-based inference algorithm suitable for electronic commerce applications. For this purpose, an Extended AND-OR Graph (EAOG) was developed with the intention that fast inference process is enabled within the electronic commerce situations. The proposed EAOG inference mechanism has the following three characteristics. 1. Real-time inference: The EAOG inference mechanism is suitable for the real-time inference because its computational mechanism is based on matrix computation. 2. Matrix operation: All the subjective knowledge is delineated in a matrix form. so that inference process can proceed based on the matrix operation which is computationally efficient. 3. Bi-directional inference: Traditional inference method of expert systems is based on either forward chaining or backward chaining which is mutually exclusive in terms of logical process and computational efficiency. However, the proposed EAOG inference mechanism is generically bi-directional without loss of both speed and efficiency. We have proved the validity of our approach with several propositions and an illustrative EC example.

• 한국지능정보시스템학회:학술대회논문집
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• 한국지능정보시스템학회 1999년도 춘계공동학술대회-지식경영과 지식공학
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• pp.353-359
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• 1999

We present a matrix-based inference alorithm suitable for electronic commerce applications. For this purpose, an Extended AND-OR Graph (EAOG) was developed with the intention that fast inference process is enabled within the electronic commerce situations. The proposed EAOG inference mechanism has the following three characteristics. 1. Real-time inference: The EAOG inference mechanism is suitable for the real-time inference because its computational mechanism is based on matric computation.2. Matrix operation: All the subjective knowledge is delineated in a matrix form, so that inference process can proceed based on the matrix operation which is computationally efficient.3. Bi-directional inference: Traditional inference method of expert systems is based on either forward chaining or backward chaining which is mutually exclusive in terms of logical process and exclusive in terms of logical process and computational efficiency. However, the proposed EAOG inference mechanism is generically bi-directional without loss of both speed and efficiency. We have proved the validity of our approach with several propositions and an illustrative EC example.

• Bulletin of the Korean Chemical Society
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• 제31권4호
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• pp.989-998
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• 2010

The titled dye of DBPI gives amplified spontaneous emission (ASE) with maximum at 580 nm upon pumping by nitrogen laser (${\lambda}_{ex}\;=\;337.1\;nm$). The ground state absorption cross section (${\sigma}_A$) and emission cross section (${\sigma}_E$) as well as effective emission cross section(${\sigma}^*_E$) have been determined. The electronic absorption spectra of DBPI were measured in ethanol and tetrahydrofuran at room and low temperature. DBPI displays molecular aggregation in water. The photochemical reactivity of DBPI was also studied in carbon tetrachloride upon irradiation with 525 nm light. The electrochemical investigation of DBPI dye has been carried out using cyclic voltammetry and convolution deconvolution voltammetry combined with digital simulation technique at a platinum electrode in 0.1 mol/L tetrabutyl ammonium perchlorate (TBAP) in two different solvents acetonitrile ($CH_3CN$) and dimethylformamide (DMF). The species were reduced via consumption of two sequential electrons to form radical anion and dianion (EE mechanism). In switching the potential to positive direction, the compound was oxidized by loss of two sequential electrons, which were followed by a fast dimerization and/or aggregation process i.e $EC_{dim1}EC_{dim2}$ mechanism. The electrode reaction pathway and the chemical and electrochemical parameters of the investigated compound were determined using cyclic and convolutive voltammetry. The extracted electrochemical parameters were verified and confirmed via digital simulation method.

• BMB Reports
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• 제49권12호
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• pp.681-686
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• 2016

Fructose 1,6-bisphosphate aldolase (FBA) is important for both glycolysis and gluconeogenesis in life. Class II (zinc dependent) FBA is an attractive target for the development of antibiotics against protozoa, bacteria, and fungi, and is also widely used to produce various high-value stereoisomers in the chemical and pharmaceutical industry. In this study, the crystal structures of class II Escherichia coli FBA (EcFBA) were determined from four different crystals, with resolutions between $1.8{\AA}$ and $2.0{\AA}$. Native EcFBA structures showed two separate sites of Zn1 (interior position) and Zn2 (active site surface position) for $Zn^{2+}$ ion. Citrate and TRIS bound EcFBA structures showed $Zn^{2+}$ position exclusively at Zn2. Crystallographic snapshots of EcFBA structures with and without ligand binding proposed the rationale of metal shift at the active site, which might be a hidden mechanism to keep the trace metal cofactor $Zn^{2+}$ within EcFBA without losing it.

• Asian Pacific Journal of Cancer Prevention
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• 제13권8호
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• pp.3751-3755
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• 2012

Aim: Tea polyphenols are known to play roles in critical steps of human lung carcinoma cell metastasis. For understanding the mechanisms whereby they inhibit tumor metastasis, the present study was conducted to investigate their effects on the adhesion of highly metastatic lung carcinoma cell lines (PG cells) to endothelial cells (EC cells) and adhesion molecule expression in vitro. Methods: The expression of CD44 or CD54 in the PG cells was detected by flow cytometry and adhesion of PG cells to EC cells was assessed by confocal microscopy double fluorescence staining. Results: The results showed that tea polyphenols: (1) inhibited the expression of CD44 and CD54, two important adhesion molecules in the PG cells in a dose-dependent manner; (2) significantly blocked the adhesion of PG cells to EC cells not only in a state of rest but also when active; and (3) influenced CD44 and CD54 expression during the adhesion process of PG cells to EC cells. Conclusions: The data indicated that the blocking role of tea polyphenols in the adhesion of PG cells to EC cells is related to CD44 and CD54. The mechanism of tea polyphenol prevention of human lung carcinoma metastasis might be through inhibiting adhesion molecule expression to block cancer cell adhesion.

• 한국동물학회지
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• 제39권1호
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• pp.75-88
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• 1996

OTF9-63 (OTF9)와 P19S1O1A1 (P19) 배종양 세포들의 체세포에 존재하는 불화성 X 염색체의 재활성과 유발 능력을 조사하였다. 배종야 세포와 체세포들의 융합에 의해 얻어진 HATr 클론들의 형태, 염색체 복제 양상을 비롯하여 X 염색체에 존재하나 그 위치는 상당히 먼 유전자들인 Hprt와 Pgk-1의 발현 양상을 분석한 결과, OTF9 세포는 불활성 X 염색체를 재활성화 시킬 수 있는데 반해 P19 세포는 불가능한 것으로 나타났다. 또한, 모든 유합세포는 장기간 배양되었을 때 성염색체의 수가 감소하였으며, 결국 1:2의 성염색체:상염색체의 비율을 나타내었다. 배종양 세포-체세포 융합세포의 이용은 초기 배발생 과정에서 시작되어 난자형성 과정의 감수분열 전까지의 유지되는 X 념색체의 재활성화 기작을 연구하기 위한 실험 방법을 제공한다.

• 대기
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• 제16권1호
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• pp.33-48
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• 2006

A classification of snowfall type based on development mechanism is proposed using previous snowfall studies, operational experiences, etc. Five types are proposed: snowfall caused by 1) airmass transformation (AT type), 2) terrain effects in a situation of expanding Siberian High (TE type), 3) precipitation systems associated with extratropical cyclones (EC type), 4) indirect effects of extratropical cyclones passing over the sea to the south of the Korean peninsula (ECS type), and 5) combined effects of TE and ECS types (COM type). Snowfall events during 1981-2001 are classified according to the 5 types mentioned above. For this, 118 events, with at least one station with daily snowfall depth greater than 20 cm, are selected. For the classification, synoptic weather charts, satellite images, and precipitation data are used. For TE and COM types, local sea-level pressure chart is also used to confirm the presence of condition for TE type (this is done for events in 1990 and thereafter). The classification shows that 109 out of 118 events can be classified as one of the 5 types. In the remaining 8 events, heavy snowfall occurred only in Ullung Island. Its occurrence may be due to one or more of the following mechanism: airmass transformation, mesoscale cyclones and/or mesoscale convergence over the East Sea, etc. Each type shows different characteristics in location of snowfall and composition of precipitation (i.e., dry snow, rain, and mixed precipitation). The AT-type snowfall occurs mostly in the west coast, Jeju and Ullung Islands whereas the TE-type snowfall occurs in the East coast especially over the Young Dong area. The ECS-type snowfall occurs mostly over the southern part of the peninsula and some east cost area (sometimes, whole south Korea depending on the location of cyclones). The EC- and COM-type snowfalls occur in wider area, often whole south Korea. Precipitation composition also varies with the type. The AT-type has a snow ratio (SR) higher than the mean value. The TE- and EC-type have SR similar to the mean. The ECS- and COM-type have SR values smaller than the mean. Generally the SR values at high latitude and mountainous areas are higher than those at the other areas. The SR value informs the characteristics of the precipitation composition. An SR value larger than 10 means that all precipitation is composed of snow whereas a zero SR value means that all precipitation is composed of rain.

• 한국정보처리학회논문지
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• 제7권4호
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• pp.1227-1235
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• 2000

In this paper, we propose new concepts that the distributed counter value with the distributed EC system identify each user who users the distributed system. The web user should register his/her own user ID in the cyber shopping mall system. Instead of registration, this paper proposes the proprietary mechanism that is distributing counter. The counter assigns the distinguished number to each client. The distributed lock algorithm is used for mutual assignment of the counter to each client. The proposed algorithm is the best solution in the distributed environment system such as cyber shopping mall. If a user should register his/her own ID in every EC system, he/she may not try to use these uncomfortable systems. The mutual counter is used to identify each client. All of these features are designed and implemented on Windows NT web server. Also these features were experiments with 5 clients for 300 times. According to the experiments, clients have their own mutual counter value. The proposed algorithm will be more efficient in internet application environment. Moreover, it will improve the number of internet users.