• 제목/요약/키워드: EAN

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의약품 물류정보화를 위한 표준 바코드 체계 (EAN-14 for Managing Drug Supply)

  • 이장룡;변의석
    • 한국경영과학회:학술대회논문집
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    • 대한산업공학회/한국경영과학회 2000년도 춘계공동학술대회 논문집
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    • pp.493-497
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    • 2000
  • 현재 국내의 바코드 체계는 거의 모든 항목에 관하여 KAN-13 코드의 체계를 이용하고 있으며, 이는 상품정보에 관련하여 국가코드, 제조업체코드, 상품품목코드, 체크디지트의 4개 부분에 각각의 성질에 따른 내용을 담아 그 상품의 특성을 나타낸다. KAN-13은 상품 각각의 성질을 나타내는 데에는 문제가 없지만 매입, 매출 및 재고업무 관리 등의 물류정보에 관련된 정보를 자동화·전산화하기 위해서는 적합하지 못하다. 이를 보충하기 위해 KAN-13 코드의 체계에 한 자리의 물류 식별코드가 추가되어 박스 단위를 표시할 수 있는 EAN-14 코드 체계의 도입이 필연적이다. 본 논문에서는 기존의 국내외 각 분야에 사용되어 진 EAN-13 코드와 EAN-14 코드의 사례를 비교 분석하여 국내의 EAN-14 코드 사용의 필연성을 제시하였고, 각 분야 중 특히 의약품의 사례를 중심으로 살펴보았다. 향후 EAN-14 코드의 체계는 좀더 구체적이고 광범위한 정보를 담고 있는 바코드 체계인 EAN-128 코드 체계의 구현을 위한 기반을 조성하게 될 것이다.

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Effect of Improving Accuracy for Effective Atomic number (EAN) and Relative Electron Density (RED) extracted with Polynomial-based Calibration in Dual-energy CT

  • Daehong Kim;Il-Hoon Cho;Mi-jo Lee
    • 한국방사선학회논문지
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    • 제17권7호
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    • pp.1017-1023
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    • 2023
  • The purpose of this study was to improve the accuracy of effective atomic number (EAN) and relative electron density (RED) using a polynomial-based calibration method using dual-energy CT images. A phantom composed of 11 tissue-equivalent materials was acquired with dual-energy CT to obtain low- and high-energy images. Using the acquired dual-energy images, the ratio of attenuation of low- and high-energy images for EAN was calibrated based on Stoichiometric, Quadratic, Cubic, Quartic polynomials. EAN and RED were extracted using each calibration method. As a result of the experiment, the average error of EAN using Cubic polynomial-based calibration was minimum. Even in the RED image extracted using EAN, the error of the Cubic polynomial-based RED was minimum. Cubic polynomial-based calibration contributes to improving the accuracy of EAN and RED, and would like to contribute to accurate diagnosis of lesions in CT examinations or quantification of various materials in the human body.

Lithium alleviates paralysis in experimental autoimmune neuritis in Lewis rats by modulating glycogen synthase kinase-3β activity

  • Meejung Ahn
    • Journal of Veterinary Science
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    • 제25권5호
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    • pp.69.1-69.10
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    • 2024
  • Importance: Guillain-Barré syndrome (GBS)-like neuropathy mimics the leading cause of sporadic acute nontraumatic limb paralysis in individuals from developed countries. Experimental autoimmune neuritis (EAN) is an animal model of GBS and of syndromes such as acute canine polyradiculoneuritis, seen in dogs and cats. Objective: The involvement of glycogen synthase kinase (GSK)-3β, a pro-inflammatory molecule, in rat EAN is not fully understood. This study evaluated the potential role of GSK-3β in EAN through its inhibition by lithium. Methods: Lewis rats were injected with SP26 antigen to induce EAN. Lithium was administered from 1 day before immunization to day 14 post-immunization (PI). Then the rats were euthanized and their neural tissues were prepared for histological and Western blotting analyses. Results: Lithium, an inhibitor of GSK-3, significantly ameliorated EAN paralysis in rats, when administered from day 1 to day 14 PI. This corresponded with reduced inflammation in the sciatic nerves of EAN rats, where phosphorylation of GSK-3β was also upregulated, indicating suppression of GSK-3. Conclusions and Relevance: These findings suggest that lithium, an inhibitor of GSK-3β, plays a significant role in ameliorating rat EAN paralysis, by suppressing GSK-3β and its related signals in EAN-affected sciatic nerves.

Effect of Total Collimation Width on Relative Electron Density, Effective Atomic Number, and Stopping Power Ratio Acquired by Dual-Layer Dual-Energy Computed Tomography

  • Jung, Seongmoon;Kim, Bitbyeol;Yoon, Euntaek;Kim, Jung-in;Park, Jong Min;Choi, Chang Heon
    • 한국의학물리학회지:의학물리
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    • 제32권4호
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    • pp.165-171
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    • 2021
  • Purpose: This study aimed to evaluate the effect of collimator width on effective atomic number (EAN), relative electron density (RED), and stopping power ratio (SPR) measured by dual-layer dual-energy computed tomography (DL-DECT). Methods: CIRS electron density calibration phantoms with two different arrangements of material plugs were scanned by DL-DECT with two different collimator widths. The first phantom included two dense bone plugs, while the second excluded dense bone plugs. The collimator widths selected were 64 mm×0.625 mm for wider collimators and 16 mm×0.625 mm for narrow collimators. The scanning parameters were 120 kVp, 0.33 second gantry rotation, 3 mm slice thickness, B reconstruction filter, and spectral level 4. An image analysis portal system provided by a computed tomography (CT) manufacturer was used to derive the EAN and RED of the phantoms from the combination of low energy and high energy CT images. The EAN and RED were compared between the images scanned using the two different collimation widths. Results: The CT images with the wider collimation width generated more severe artifacts, particularly with high-density material (i.e., dense bone). RED and EAN for tissues (excluding lung and bones) with the wider collimation width showed significant relative differences compared to the theoretical value (4.5% for RED and 20.6% for EAN), while those with the narrow collimation width were closer to the theoretical value of each material (2.2% for EAN and 2.3% for RED). Scanning with narrow collimation width increased the accuracy of SPR estimation even with high-density bone plugs in the phantom. Conclusions: The effect of CT collimation width on EAN, RED, and SPR measured by DL-DECT was evaluated. In order to improve the accuracy of the measured EAN, RED, and SPR by DL-DECT, CT scanning should be performed using narrow collimation widths.

EAN을 이용한 한글 전자우편 시스템의 구현 (Implementation of Hangul Message Handling System Using EAN)

  • 임재홍;신의섭;오익균;박용진
    • 대한전기학회:학술대회논문집
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    • 대한전기학회 1987년도 전기.전자공학 학술대회 논문집(II)
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    • pp.1022-1025
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    • 1987
  • This paper describes the implementation of HMHS (Hangul Message Handling System) using EAN based on CClTT X.400 protocols and X.200 protocols. The implemented HMHS allows users to use Hangul user name, Hangul address and Hangul commands as well as English.

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Nitrox 공기통의 기체 분석에 의한 스쿠버다이버 사망원인 추정에 관한 사례연구 (Case on the Death of Scuba Diver by Analyzing the Air in Nitrox Cylinder)

  • 이준배;유재훈;손성건;성태명;팽기정
    • 한국안전학회지
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    • 제26권2호
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    • pp.42-47
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    • 2011
  • Going underwater is supposed to begin with the history of human beings. At first it was confined to relatively shallow level, less than several meters by holding breath. Recently, deep level diving has been necessary for such purpose as construction, maritime salvage, military operations, research and sports by using SCUBA(self-contained underwater breathing apparatus) equipment. As one goes down into water, the pressure on the diver is increased due to water pressure with depth, usually 1 atm for each 10 m water level. In deep water, mixed gas or nitrox(EAN, enriched air nitrox) could be applied for the divers lest they should get disease due to high pressure. Of these, the former is usually composed of oxygen and inert gas like helium or hydrogen, the latter contains higher oxygen content than that in normal air in which the oxygen concentration is designated by the character "EAN" followed by vol. % of oxygen, for example, "EAN 40" contains 40% of oxygen. In this case, a victim was found at the 39 m below the sea surface breathing air and nitrox in cylinder wrongly marked as EAN 36, which was analyzed to contain 63% of oxygen by GC/TCD. The cause of death could not be exactly related with the oxygen content in the nitrox cylinder, because the accurate depth for the victim to dive was not known, even though the victim was just found at the depth of 39 m. However, the wrongly marked nitrox could be believed to be the main cause of the death at the depth unless there happened any other accident except that during diving.

실험적 자가면역성 말초신경염에서의 조직병리적 병변 및 CD5+ B-림프구의 발현 (Histopathologic Features and CD5+ B-lymphocyte Expression in the Experimental Allergic Neuritis)

  • 조중양;최원준;김성훈;성정준;김호진;박경석;최기영;김현정;이광우
    • Annals of Clinical Neurophysiology
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    • 제1권2호
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    • pp.91-98
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    • 1999
  • Background : The pathogenesis of acute inflammatory demyelinating polyradiculoneuropathy (AIDP), Guillain Barre syndrome (GBS) is not clear, but it has been known that the immune mechanisms play an important role. Authors performed this study to establish an animal model of experimental allergic neuritis (EAN) by immunizing the myelin components of peripheral nerves and to understand the electrophysiological and histopathological features as well as the ${CD_5}^+$ B-lymphocyte changes in peripheral bloods in the EAN models. Methods : Lewis rats weighing 150-200 gm were injected subcutaneously in soles two times with total myelin, P0, P1, or P2 proteins purified from the bovine cauda eguina. The EAN induction was assessed by evaluating clinical manifestations. The electrophysiological and histopathological features were studied as routine methods. The ${CD_5}^+$ Blymphocytes were double stained using monoclonal FITC conjugated anti-rat CD45RA and R-PE conjugated anti-rat ${CD_5}^+$ antibodies and calculated using a fluorescence activated cell sorter (FACS). Results : The EAN animal models were established. In two out of five, in one out of two, in none out of three, and in none out of one Lewis rats injected with purified total myelin, P0, P1, P2 proteins respectively, They showed slow spontaneous motor activity and weak resistance against pulling back by tails. The typical electrophysiological and histologic findings in total protein and P0 induced EAN animal models were the decreased conduction velocity, the decreased compound muscle action potential (CMAP) amplitude and the dispersion phenomenon. The perivascular infiltrates of lymphocytes with focal demyelinating process were found in light microscopy. The ${CD_5}^+$ B-lymphocyte expression in three EANs were 2.38%, 3.50% 2.50%, which were not significantly increased, compared with those in normal controls. Conclusion : The EAN animal models were successfully established by injecting the total myelin and P0 myelin and they showed electrophysiological and histological features typical of demyelinating process. However they did not show an increased expression of ${CD_5}^+$ B-lymphocyte in peripheral bloods which could be indirect evidence of humoral autoimmunity.

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Development of Impact Table and optimum combination dedication module for green-remodeling advance business value assessment

  • Choi, Jun-Woo;Kim, Gyoung-Rok;Ko, Jung-Lim;Shin, Jee-Woong;Lee, Keon-Ho
    • KIEAE Journal
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    • 제16권3호
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    • pp.5-12
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    • 2016
  • Purpose: In case of existing building, A lot of attempts are being made like changing thermal system or using high efficiency products to decrease energy load and increase energy efficiency. However, (1) Absence of systemed database of green-remodeling technology and products. (2) Absence of comparative analysis system and qualitative/quantitative evaluation method of energy performance and energy reduction cost. (3) Existing remodeling was very hard to access for non-experts. So, in this paper, the authors developed data base for green-remodeling(Impact Table A, Impact Table B) and optimum combination dedication tool for user convenience. Accordingly, purpose of this paper validate usefulness of Impact Table and optimum alternative dedication tool. Method: For validate the usefulness of Impact Table and optimum combination dedication tool, the authors selected five test model office buildings. Next, through research investigation, the authors diagnosed the present state of buildings. In base of diagnosis results, select technologies for remodeling by qualitative comparison (Impact Table A). Next, evaluate quantitative price and performance technologies that selected in Impact Table A (Impact Table B). Lastly, through final evaluation of Impact Taba A and Impact Table B, determine the direction of the green-remodeling. Result: Impact Table and optimum combination dedication tool can use relative indicator for green-remodeling, especially through ROI by detail field.