• KIEAE Journal
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• 제10권2호
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• pp.9-18
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• 2010

As an aging population has increased vastly and nuclear families have been a dominating family type in modern Korean society, the numbers of the elderly who suffer Empty Nest Syndrome and LID (Loss Isolation Depression) syndrome have been accelerated. These syndromes involve psychological instability, melancholy, and lethargy. To make the elderly get out of this phenomenon and live actively, the scheme of converting their existing house into shared housing was set as a hypothetical solution in this study. This study sets out to find out responses of the elderly to alter their own house's function in housing improvement area. A Small Workshop Panel method was used and the elderly aged 55 years upwards took part and they own a detached house in a housing improvement area that is relatively large for the elderly or the elderly couple to live alone. Through the workshop, problems that the elderly have been experiencing within their houses were looked into and responses of the elderly on altering their house to shared housing by introducing developed schematic plans. Although, the first response was negative, positive responses from the house owners were carried out when a visual support i.e. developed shared housing plan was provided. The positive response was based on the fact that subsidies from the government on house renovation and tenants matching programs are supported as shared housing could provide home owners economical support with rents and help them to feel less lonely. This is a way of relieving the elderly from being neglected and supporting them to live and age actively in their later lives. Furthermore, by providing a visual media to the elder residents in housing improvement area, their greater understandings on the development and addressing their opinions were possible. Therefore, more tools that promote elder residents' participation are needed for future housing improvement projects and an aging society.

• 한국지구과학회지
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• 제26권7호
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• pp.714-724
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• 2005

The East Sea, a semi-enclosed marginal sea with shallow straits in the northwest Pacific, is marked by the nearly geographic isolation and the low sea surface salinity during the last glacial maximum (LGM). The East Sea might have the only connection to the open ocean through the Korea Strait with a sill depth of 130 m, allowing the paleo-Tsushima Water to enter the sea during the LGM. The low paleosalinity associated with abnormally light $\delta^{18}O$ values of planktonic foraminifera is interpreted to have resulted from river discharge and precipitation. Nevertheless, two LGM features in the East Sea are disputable. This study attempts to estimate volume transport of the paleo-Tsushima Water via the Korea Strait and further examines its effect on the low sea surface salinity (SSS) during the lowest sea level of the LGM. The East Sea was not completely isolated, but partially linked to the northern East China Sea through the Korea Strait during the LGM. The volume transport of the paleo-Tsushima Water during the LGM is calculated approximately$(0.5\~2.1)\times10^{12}m^3/yr$ on the basis of the selected seismic reflection profiles along with bathymetry and current data. The annual influx of the paleo-Tsushima Water is low, compared to the 100 m-thick surface water volume $(about\;79.75\times10^{12}m^3)$ in the East Sea. The paleo-Tsushima Water influx might have changed the surface water properties within a geologically short time, potentially decreasing sea surface salinity. However, the effect of volume transport on the low sea surface salinity essentially depends on freshwater amounts within the paleo-Tsushima Water and excessive evaporation during the glacial lowstands of sea level. Even though the paleo-Tsushima Water is assumed to have been entirely freshwater at that time period, it would annually reduce only about 1‰ of salinity in the surface water of the East Sea. Thus, the paleo-Tsushima Water influx itself might not be large enough to significantly reduce the paleosalinity of about 100 m-thick surface layer during the LGM. This further suggests contribution of additional river discharges from nearby fluvial systems (e.g. the Amur River) to freshen the surface water.

• Parasites, Hosts and Diseases
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• 제55권3호
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• pp.239-246
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• 2017

Strains of Toxoplasma gondii in Brazil are highly genetically diverse compared to strains from North America and Europe. Dogs are epidemiologically important because they act as sentinels for T. gondii infections in humans and are good indicators of environmental contamination. The aim of this study was to isolate and genetically characterize T. gondii strains from tissues of naturally infected Brazilian dogs. For this study, 21 blood samples were collected from dogs at the Zoonosis Control Centers of $Ilh{\acute{e}}us$ and Itabuna cities, Bahia, Brazil. The sera were examined for T. gondii antibodies using the indirect hemagglutination test. Brains and hearts of seropositive dogs were bioassayed in mice to isolate and characterize T. gondii parasites by PCR-RFLP using 10 genetic markers (SAG1, newSAG2, SAG3, BTUB, c22-8, c29-2, GRA6, PK1, APICO, and L358). However, T. gondii was isolated from only 4 (57.1%) dogs, designated TgDgBr6, 13, 17, and 21. All strains were virulent, causing clinical changes (rough hair coat, lethargy, and abdominal distention) and the death of all mice within 8-20 days after inoculation. Genetic analysis of these 4 T. gondii isolates revealed 4 distinct genotypes with different clonal lineage combinations (types I, II, and III) and 2 atypical alleles. Using PCR-RFLP with several markers, this study contributes to evaluations of the genetic diversity of strains circulating in Brazil.

• Asian-Australasian Journal of Animal Sciences
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• 제15권7호
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• pp.1040-1044
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• 2002

The efficacy of an organic acid solution in the prevention of neonatal kid diarrhoea, was examined in this study and was compared with that of different antibiotics. In a goat farm, kids and their mothers were divided in 4 experimental groups. The kids of Group I were not given any treatment serving as negative controls. The kids of Group II were treated orally for 3 consecutive days with a solution of organic acids starting approximately 12 h after their birth. The kids of Groups III and IV were treated once orally with ampicillin and oxytetracycline respectively, approximately 12 h after birth. All groups were compared as regards the occurrence of diarrhoea, its duration, and the rate of mortality. The results have shown that the number of cases and the duration of diarrhoea were significantly reduced in all treated groups, when compared to the control group (p<0.05). However, no or little difference was noted with respect to morbidity, mortality and diarrhoea characteristics when treated groups were compared with each other (p>0.05). Samples of diarrhoeic faeces from kids in the control group resulted in the isolation of K88 and K99 strains of Escherichia coli. It was concluded that, early oral administration of organic acids can be effective in the prevention of scours in neonatal kids, possibly caused by enterotoxigenic E. coli strains, and to a degree of protection similar to that seen with the used antibiotic schemes.

• 대한전자공학회논문지TC
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• 제42권3호
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• pp.33-38
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• 2005

본 논문에서는 표면 마이크로 머시닝 기법으로 구현된 DAML (Dielectric-supported Airbridge Microstrip Line) 형태의 새로운 구조를 이용하여 $180^{\circ}$ 링 하이브리드 결합기를 설계 및 제작 하였다. DAML 구조로 이용하여 제작된 결합기는 60 GHz 중심 주파수에서 3.58 dB의 S31과 3.31 dB의 S21과 61 GHz에서 16.17 dB 이상의 S11과 55 dB 이상의 S41를 얻을 수 있다. 결합기의 크기를 줄이기 위하여 slow wave 구조가 삽입된 결합기를 설계 제작하였으며 크기를 $33\%$ 정도 줄일 수 있는 효과를 얻을 수 있었다.

• 대한전자공학회논문지TC
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• 제38권12호
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• pp.49-57
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• 2001

이 논문에서는 실리콘 기판 등가 회로 모델과 새로운 모델 파라미터 추출 방법을 보인다. 등가 회로 모델을 해석함으로써 회로 블록 사이의 기판 커플링 특성을 고찰하고, 커플링의 크기를 회로 동작 주파수와 특성 주파수(시스템의 폴과 제로 주파수)를 사용하여 분석함으로써 기판 커플링의 물리적 특성을 정량적으로 해석하였다. 제안된 등가회로 모델과 모델 파라미터 추출 방법의 정확성과 타당성을 실험적으로 검증하기 위하여 표준 CMOS 공정을 사용하여 다양한 거리와 기판 저항, 그리고 가드링 구조를 갖는 테스트 패턴을 설계, 제작하고 100 MHz-20 GHz 주파수 영역에서 측정하였다. 그리고 실리콘 기판 등가 회로 모델 을 사용하여 HSPICE를 사용하여 시뮬레이션하고 그 결과를 측정 결과와 비교함으로써 제안된 회로 모델과 파라미터 추출 방법의 정확성을 보였다. 따라서 등가 회로 모델과 파라미터 추출 방법은 정확한 혼성 신호 회로 디자인과 효과적인 시스템의 성능 검증에 유용하게 사용될 수 있다.

• 한국수의병리학회지
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• 제3권1호
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• pp.35-44
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• 1999

The morphologic changes of small intestinal epithelium in pigs diagnosed as porcine epidemic diarrhea(PED} by virus isolation and immunohistochemistry were studied through light microscope and transmissible electron microscope. On semi-thin section, the histologic findings showed severe villous atrophy and fusion with hyperplasia of cuboidal epithelium in the villi, inflammatory cell infiltration in lamina propria, and increased mitotic figures in the crypt. The structural changes were mostly restricted to the cytoplasm of affected absorptive epithelium of villi. 3 types of epithelial changes were found; degenerated virus-affected cells, undifferentiated cuboidal cells, and normal columnar cells. On electron microscopy, round to spherical viral particles of 50∼l00nm in diameter were found within the dilated vesicles and endoplasmic reticulums of degenerated cells, which had decreased their cytoplasmic electron density due to dilated and missing organelles(e.g. mitochondria, ERs, etc.). Microvilli were shortened and sparse, leaving denuded terminal web of the villous epithelial cells. Fat globules were often found within slightly degenerated enterocytes. On the tip of villi, severely damaged cells were exfoliated and replaced by undifferentiated cuboidal cells We found distinct ultrastructural changes in the jejunal epithelium confirming PED virus infection is involved in malabsorptive diarrhea.

• 한국식품위생안전성학회지
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• 제15권2호
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• pp.128-136
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• 2000

수입 냉동어패류에서 24주의 Vibiro 균주를 순수 분리하여 그들의 생리, 생화학적 특성에 따라 동정한 결과 V. cholerae non-O1과 V. diazotrophicus가 각 2주, V. hollisae 1주, V. natriegens 5주, V. fluvialis 8주, V. nereis 4주인 것으로 밝혀졌고 2주는 Vibirio속 균주가 아닌 것으로 나타났다. 이 균주들을 API-2OE kit로 동정한 결과는 위의 결과와 매우 달라, V. cholerae로 동정된 2주와 fluvialis로 동정된 5균주의 경우에만 결과가 일치하였고 나머지는 Vibrio속이 아닌 것으로 분석되었다. 식품류에서 V. cholerae가 검출된 점에 주목하여 이 분리균들의 동정을 보다 정확히 하기 위하여 분리균들의 165 rRNA를 증폭시켜 이들의 RFLP를 분석하였다. 그 결과, r cholerae로 동정된 두 균주는 동일한 RFLP양상을 갖고 있었으며, V. cholerae보다는 V. proteolyticus의 RFLP에 보다 가까운 것으로 나타났다. 따라서 식품류의 병원균 검색을 보다 정확하고 신속하게 할 수 있도록 효율적인 검색 방법의 개발이 시급하다고 하겠다.

• 대한소아치과학회지
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• 제11권1호
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• pp.75-89
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• 1984

A total of 141 strains of Streptococcus mutans were isolated from dental plaques of 153 subjects. Eighty-two children with caries-experience, 18 caries-free children and their mothers were participated. All isolates were examined for their serotypes by immunodiffusion method with 7 reference sera and their antibiotic susceptibilities to 7 antibiotics by agar dilution method using 7 kinds of antibiotics, and were compared their results by caries experience (DMFT ratio) and by intrafamilial levels. 1. Isolation rate of Streptococcus mutans were greater in samples of carious teeth than those of sound teeth, and in mothers than in children. 2. Multiple serotypes of Streptococcus mutans were occasionally found in a single samples. 3. Of the total 141 isolates (83 isolates from children, and 58 from their mothers), type c isolates were most prevalent (63.8%). Type d,e and f were found, comprizing 14.9%, 10.6% and 6.4% respectively. Serotype g, a and untypable strain were also found but far lower frequencies (2.8-0.7%), and type b was detected. 4. These results suggest that there are no significant correlation among the distribution of serotypes, antibiotic susceptibilities, caries experience and intrafamilial relationships. 5. Most of isolates were susceptible to chloramphenicol (100%), penicillin (95.7%), ampicillin (94.3%), and gentamicin (92.2%), but about one-third isolates were resistant to cephaloridine (27%), streptomycin (33.3%) and kanamycin (47.6%), resulting that 91 strains (64.5%) among 141 isolates were resistant to one or more drugs used. 6. Of the 91 resistant strains, 20 different resistant patterns were observed, and the most frequently encountered patterns were KM, SM and CE.

• Fisheries and Aquatic Sciences
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• 제16권1호
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• pp.1-5
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• 2013

To assess the feasibility of phlorotannins from Eisenia bicyclis as cancer chemopreventative agents, we tested whether they induced quinone reductase (QR) in Hepa1c1c7 cells. The ethyl acetate (EtOAc) soluble fraction obtained from E. bicyclis exhibited a QR induction activity in Hepa1c1c7 cells. Successive column chromatography of the active EtOAc fraction resulted in the isolation of four phlorotannins. Their structures were elucidated using one- and two-dimensional nuclear magnetic resonance spectroscopic techniques and characterized as phloroglucinol (1), dioxinodehydroeckol (2), dieckol (3), and fucofuroeckol-A (4). Among these compounds, fucofuroeckol-A (4) showed moderate QR induction activity, and dioxinodehydroeckol (2) exhibited potent QR induction potency with $2.05{\pm}0.04$ fold induction at a concentration of $50{\mu}M$ compared to the dimethyl sulfoxide solvent-treated control cells. However, phloroglucinol (1) and dieckol (3) exerted no detectable QR induction activity in Hepa1c1c7 cells. These results suggest that dioxinodehydroeckol could serve as a useful cancer chemopreventive chemical.