• KIEAE Journal
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• v.10 no.2
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• pp.9-18
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• 2010

As an aging population has increased vastly and nuclear families have been a dominating family type in modern Korean society, the numbers of the elderly who suffer Empty Nest Syndrome and LID (Loss Isolation Depression) syndrome have been accelerated. These syndromes involve psychological instability, melancholy, and lethargy. To make the elderly get out of this phenomenon and live actively, the scheme of converting their existing house into shared housing was set as a hypothetical solution in this study. This study sets out to find out responses of the elderly to alter their own house's function in housing improvement area. A Small Workshop Panel method was used and the elderly aged 55 years upwards took part and they own a detached house in a housing improvement area that is relatively large for the elderly or the elderly couple to live alone. Through the workshop, problems that the elderly have been experiencing within their houses were looked into and responses of the elderly on altering their house to shared housing by introducing developed schematic plans. Although, the first response was negative, positive responses from the house owners were carried out when a visual support i.e. developed shared housing plan was provided. The positive response was based on the fact that subsidies from the government on house renovation and tenants matching programs are supported as shared housing could provide home owners economical support with rents and help them to feel less lonely. This is a way of relieving the elderly from being neglected and supporting them to live and age actively in their later lives. Furthermore, by providing a visual media to the elder residents in housing improvement area, their greater understandings on the development and addressing their opinions were possible. Therefore, more tools that promote elder residents' participation are needed for future housing improvement projects and an aging society.

• Journal of the Korean earth science society
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• v.26 no.7
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• pp.714-724
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• 2005

The East Sea, a semi-enclosed marginal sea with shallow straits in the northwest Pacific, is marked by the nearly geographic isolation and the low sea surface salinity during the last glacial maximum (LGM). The East Sea might have the only connection to the open ocean through the Korea Strait with a sill depth of 130 m, allowing the paleo-Tsushima Water to enter the sea during the LGM. The low paleosalinity associated with abnormally light $\delta^{18}O$ values of planktonic foraminifera is interpreted to have resulted from river discharge and precipitation. Nevertheless, two LGM features in the East Sea are disputable. This study attempts to estimate volume transport of the paleo-Tsushima Water via the Korea Strait and further examines its effect on the low sea surface salinity (SSS) during the lowest sea level of the LGM. The East Sea was not completely isolated, but partially linked to the northern East China Sea through the Korea Strait during the LGM. The volume transport of the paleo-Tsushima Water during the LGM is calculated approximately$(0.5\~2.1)\times10^{12}m^3/yr$ on the basis of the selected seismic reflection profiles along with bathymetry and current data. The annual influx of the paleo-Tsushima Water is low, compared to the 100 m-thick surface water volume $(about\;79.75\times10^{12}m^3)$ in the East Sea. The paleo-Tsushima Water influx might have changed the surface water properties within a geologically short time, potentially decreasing sea surface salinity. However, the effect of volume transport on the low sea surface salinity essentially depends on freshwater amounts within the paleo-Tsushima Water and excessive evaporation during the glacial lowstands of sea level. Even though the paleo-Tsushima Water is assumed to have been entirely freshwater at that time period, it would annually reduce only about 1‰ of salinity in the surface water of the East Sea. Thus, the paleo-Tsushima Water influx itself might not be large enough to significantly reduce the paleosalinity of about 100 m-thick surface layer during the LGM. This further suggests contribution of additional river discharges from nearby fluvial systems (e.g. the Amur River) to freshen the surface water.

• Parasites, Hosts and Diseases
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• v.55 no.3
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• pp.239-246
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• 2017

Strains of Toxoplasma gondii in Brazil are highly genetically diverse compared to strains from North America and Europe. Dogs are epidemiologically important because they act as sentinels for T. gondii infections in humans and are good indicators of environmental contamination. The aim of this study was to isolate and genetically characterize T. gondii strains from tissues of naturally infected Brazilian dogs. For this study, 21 blood samples were collected from dogs at the Zoonosis Control Centers of $Ilh{\acute{e}}us$ and Itabuna cities, Bahia, Brazil. The sera were examined for T. gondii antibodies using the indirect hemagglutination test. Brains and hearts of seropositive dogs were bioassayed in mice to isolate and characterize T. gondii parasites by PCR-RFLP using 10 genetic markers (SAG1, newSAG2, SAG3, BTUB, c22-8, c29-2, GRA6, PK1, APICO, and L358). However, T. gondii was isolated from only 4 (57.1%) dogs, designated TgDgBr6, 13, 17, and 21. All strains were virulent, causing clinical changes (rough hair coat, lethargy, and abdominal distention) and the death of all mice within 8-20 days after inoculation. Genetic analysis of these 4 T. gondii isolates revealed 4 distinct genotypes with different clonal lineage combinations (types I, II, and III) and 2 atypical alleles. Using PCR-RFLP with several markers, this study contributes to evaluations of the genetic diversity of strains circulating in Brazil.

• Asian-Australasian Journal of Animal Sciences
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• v.15 no.7
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• pp.1040-1044
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• 2002

The efficacy of an organic acid solution in the prevention of neonatal kid diarrhoea, was examined in this study and was compared with that of different antibiotics. In a goat farm, kids and their mothers were divided in 4 experimental groups. The kids of Group I were not given any treatment serving as negative controls. The kids of Group II were treated orally for 3 consecutive days with a solution of organic acids starting approximately 12 h after their birth. The kids of Groups III and IV were treated once orally with ampicillin and oxytetracycline respectively, approximately 12 h after birth. All groups were compared as regards the occurrence of diarrhoea, its duration, and the rate of mortality. The results have shown that the number of cases and the duration of diarrhoea were significantly reduced in all treated groups, when compared to the control group (p<0.05). However, no or little difference was noted with respect to morbidity, mortality and diarrhoea characteristics when treated groups were compared with each other (p>0.05). Samples of diarrhoeic faeces from kids in the control group resulted in the isolation of K88 and K99 strains of Escherichia coli. It was concluded that, early oral administration of organic acids can be effective in the prevention of scours in neonatal kids, possibly caused by enterotoxigenic E. coli strains, and to a degree of protection similar to that seen with the used antibiotic schemes.

• Journal of the Institute of Electronics Engineers of Korea TC
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• v.42 no.3 s.333
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• pp.33-38
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• 2005

In this paper, we have designed and fabricated a hybrid ring coupler to prove the fabrication possibility of various passive components, applying millimeter wave using newly proposed transmission lines, i.e. BAMLs. The characteristics of the fabricated hybrid ing coupler were a the S31(coupling) of 3.58 dB, the S21(thru) of 3.31 dB at the 60 GHz center frequency, the S11(return loss) over 16.17 dB, S41(isolation) over 55 dB at 61 GHz, and the phase difference between port 2 and port 3 of $180{\pm}loat$ 60GHz. In order to reduce the size of hybrid ring coupler, we designed the hybrid ring coupler which inserts a slow wave structure. With this structure, we were able to reduce the hybrid ring coupler by $33\%$ area.

• Journal of the Institute of Electronics Engineers of Korea TC
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• v.38 no.12
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• pp.49-57
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• 2001

In this paper, equivalent circuit model and novel model parameter extraction method of a silicon(Si) substrate are presented. Substrate coupling through Si-substrate is quantitatively investigated by analyzing equivalent circuit with operating frequency and characteristic frequencies (i.e., pole and zero frequency) of a system. For the experimental verification of the equivalent circuit and parameter extraction method, test patterns are designed and fabricated in standard CMOS technology with various isolation distances, substrate resistivity, and guard-ring structures. Then, these are measured in l00MHz-20GHz frequency range by using vector network analyzer. It is shown that the equivalent-circuit-based HSPICE simulation results using extracted parameters have excellent agreement with the experimental results. Thus, the proposed equivalent circuit and parameter extraction methodology can be usefully employed in mixed-signal circuit design and verification of a circuit performance.

• Korean Journal of Veterinary Pathology
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• v.3 no.1
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• pp.35-44
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• 1999

The morphologic changes of small intestinal epithelium in pigs diagnosed as porcine epidemic diarrhea(PED} by virus isolation and immunohistochemistry were studied through light microscope and transmissible electron microscope. On semi-thin section, the histologic findings showed severe villous atrophy and fusion with hyperplasia of cuboidal epithelium in the villi, inflammatory cell infiltration in lamina propria, and increased mitotic figures in the crypt. The structural changes were mostly restricted to the cytoplasm of affected absorptive epithelium of villi. 3 types of epithelial changes were found; degenerated virus-affected cells, undifferentiated cuboidal cells, and normal columnar cells. On electron microscopy, round to spherical viral particles of 50∼l00nm in diameter were found within the dilated vesicles and endoplasmic reticulums of degenerated cells, which had decreased their cytoplasmic electron density due to dilated and missing organelles(e.g. mitochondria, ERs, etc.). Microvilli were shortened and sparse, leaving denuded terminal web of the villous epithelial cells. Fat globules were often found within slightly degenerated enterocytes. On the tip of villi, severely damaged cells were exfoliated and replaced by undifferentiated cuboidal cells We found distinct ultrastructural changes in the jejunal epithelium confirming PED virus infection is involved in malabsorptive diarrhea.

• Journal of Food Hygiene and Safety
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• v.15 no.2
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• pp.128-136
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• 2000

Twenty-four Vibrio strains were isolated from imported frozen seafoods and identified according to their physiological and biochemical properties. They included two V cholerae non-01 sp., two V. diazotrophicus sp., one V. hollisae sp., five V. natriegens sp., eight V. fluvialis sp., and four V. nereis sp.. Two of them were not identified as Vibrio species. When these strains were tested using API-2OE kit fur identification, however, only the results for two V. cholerae and five of the V. fluvialis strains matched the results obtained previously. Due to the importance of detecting V cholerae from foods, phylogenetic identification of the strains was attempted based on restriction fragment length polymorphism (RFLP) of the 16S rDNAs amplified by PCR. The results suggested that the two strains had identical RFLP patterns which were more closely related to that of V. proteolyticus than V. cholerae. The problems associated with identification of pathogens originated from seafoods demand development of accurate and rapid identification methods.

• Journal of the korean academy of Pediatric Dentistry
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• v.11 no.1
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• pp.75-89
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• 1984

A total of 141 strains of Streptococcus mutans were isolated from dental plaques of 153 subjects. Eighty-two children with caries-experience, 18 caries-free children and their mothers were participated. All isolates were examined for their serotypes by immunodiffusion method with 7 reference sera and their antibiotic susceptibilities to 7 antibiotics by agar dilution method using 7 kinds of antibiotics, and were compared their results by caries experience (DMFT ratio) and by intrafamilial levels. 1. Isolation rate of Streptococcus mutans were greater in samples of carious teeth than those of sound teeth, and in mothers than in children. 2. Multiple serotypes of Streptococcus mutans were occasionally found in a single samples. 3. Of the total 141 isolates (83 isolates from children, and 58 from their mothers), type c isolates were most prevalent (63.8%). Type d,e and f were found, comprizing 14.9%, 10.6% and 6.4% respectively. Serotype g, a and untypable strain were also found but far lower frequencies (2.8-0.7%), and type b was detected. 4. These results suggest that there are no significant correlation among the distribution of serotypes, antibiotic susceptibilities, caries experience and intrafamilial relationships. 5. Most of isolates were susceptible to chloramphenicol (100%), penicillin (95.7%), ampicillin (94.3%), and gentamicin (92.2%), but about one-third isolates were resistant to cephaloridine (27%), streptomycin (33.3%) and kanamycin (47.6%), resulting that 91 strains (64.5%) among 141 isolates were resistant to one or more drugs used. 6. Of the 91 resistant strains, 20 different resistant patterns were observed, and the most frequently encountered patterns were KM, SM and CE.

• Fisheries and Aquatic Sciences
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• v.16 no.1
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• pp.1-5
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• 2013

To assess the feasibility of phlorotannins from Eisenia bicyclis as cancer chemopreventative agents, we tested whether they induced quinone reductase (QR) in Hepa1c1c7 cells. The ethyl acetate (EtOAc) soluble fraction obtained from E. bicyclis exhibited a QR induction activity in Hepa1c1c7 cells. Successive column chromatography of the active EtOAc fraction resulted in the isolation of four phlorotannins. Their structures were elucidated using one- and two-dimensional nuclear magnetic resonance spectroscopic techniques and characterized as phloroglucinol (1), dioxinodehydroeckol (2), dieckol (3), and fucofuroeckol-A (4). Among these compounds, fucofuroeckol-A (4) showed moderate QR induction activity, and dioxinodehydroeckol (2) exhibited potent QR induction potency with $2.05{\pm}0.04$ fold induction at a concentration of $50{\mu}M$ compared to the dimethyl sulfoxide solvent-treated control cells. However, phloroglucinol (1) and dieckol (3) exerted no detectable QR induction activity in Hepa1c1c7 cells. These results suggest that dioxinodehydroeckol could serve as a useful cancer chemopreventive chemical.