• The Journal of the Korea Contents Association
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• v.10 no.8
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• pp.95-103
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• 2010

Raw files record luminance values corresponds to each pixel of a digital camera sensor. In digital imaging, controlling exposure to capture the first highlight stop is important on linear-distribution of raw file characteristic. This study sought to verify the efficiency of ETTR method and found the optimum over-exposure amount to maintain the first highlight stop to be the largest number of levels. This was achieved by over-exposing a scene with a raw file and converting it to under-exposure in a raw file converting software. Our paper verified the efficiency of ETTR by controlling the exposure range and ISOs. Throughout the results, if exposure increases gradually 6 steps, dynamic range is also increased. And it shows that the optimized exposure value is around + $1\frac{2}{3}$ stop over compared to the normal exposure with the high ISOs simultaneously. We compared visual noise value at $1\frac{2}{3}$ stop to the normal exposure visual noise. Based on the normal exposure's visual noise, we can confirm that visual noise decrement is increased by increasing ISOs. In this experimental result, we confirm that overexposure about + $1\frac{2}{3}$ stop is the optimum value to make the widest dynamic range and lower visual noise in high ISOs. Based on the study results, we can provide the effective ETTR information to consumers and manufacturers. This method will contribute to the optimum image performance in maximizing dynamic range and minimizing noise in a digital imaging.

• Macromolecular Research
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• v.17 no.2
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• pp.99-103
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• 2009

We evaluated the efficacy of pH-sensitive micelles, formed by methoxy poly(ethylene glycol)-b-poly($\beta$)-amino ester) (PEG-PAE), as carriers for paclitaxel (PIX), a drug currently used to treat various cancers. PTX was successful encapsulated by a film hydration method. Micelles encapsulated more than 70% of the PTX and the size of the PTX-encapsulated micelles (PTX-PM) was less than 150 nm. In vitro experiments indicated that the micelles were unstable below pH 6.5. After encapsulation of PTX within the micelles, dynamic light scattering (DLS) studies indicated that low pH had a similar demicellization effect. An in vitro release study indicated that PTX was slowly released at pH 7.4 (normal body conditions) but rapidly released under weakly acidic conditions (pH 6.0). We demonstrated the safety of micelles from in vitro cytotoxicity tests on HeLa cells and the in vivo anti-tumor activity of PTX-PM in B16F 10 tumor-bearing mice. We concluded that these pH-sensitive micelles have potential as carriers for anti-cancer drugs.

• Journal of The Korean Association of Information Education
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• v.4 no.1
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• pp.57-71
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• 2000

Generally, Web Based Instruction has been deployed through whole studies, but the characteristic that is suit various WBI materials to a course of study is a important problem of instructional practice and it also has not to overlook. Therefore, Today's problem that is application of learning materials about the regional autonomy for Web Based Instruction, A plan that it can be solved in the social studies is propelling in this paper. Each of the whole country's region, the learning about the regional autonomy with centering around text, it is a text book, 'Social Investigation', that is developed specially is teaching until now, but developmental model of learning materials about the regional autonomy for Web Based Instruction is proposed by the efforts for improve this problem. Various learning materials about the regional autonomy for Web Based Instruction applied to learn our regional cultural life through the school homepage with based on this proposal. As a result of this study, By sloughing off old sensibility with centering around text, Student's Ability of self directed learning and solving problem is expanded with the dynamic multimedia regional Webpage's environment

• Korean Institute of Interior Design Journal
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• v.16 no.6
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• pp.77-85
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• 2007

The space where one's body lives is not only a space as the simple environment that is built with the physical factors, but also a space experienced by a movement accompanied by the concept of body perception including mental activities. In this study, the importance of the body is recognized and the meaning of the space of body perception including mental activities is understood. In this manner, the spatial unfolding phase and expression features are to be investigated through a standard of "What do they change?" by grasping those as a flexible space that changes spatial recognition. The following results have been drawn in this study; First, the application of the flexible concept in the space can give rise to the activities of an experiencing person in terms of being the object of spatial experience and appreciation. Also, the application changes a slightly static concept into a relative and dynamic space by introducing the movement. Second, the establishment of a space by a human's movement is accompanied by all perceptions and enables to perceive the space shape, the space itself and mutual communication between the spaces. Third, the expression of the human's movement in the fixed form of space lies in the extension of the fused spacial area with an observer beyond the physical spatial limitation. As human body intervenes in space, the meaning of the space has become more abundant and diverse and the space will be presented as the arena for sensitive and flexible communication as a responsive space that corresponds.

• Korean Chemical Engineering Research
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• v.46 no.4
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• pp.799-805
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• 2008

In general, anionic and cationic surfactants are incompatible because their mixtures form insoluble complexes and precipitate in the water. There are, however, some equimolar complexes of anionic and cationic surfactant that are soluble and behave like regular surfactants, specifically like nonionic surfactants, thus named pseudo-nonionic surfactant complexes. Pseudo-nonionic complexes are more effective and efficient in surface activities than their ionic surfactant components as shown by their equilibrium and dynamic surface tensions. They pack at the interface more than their ionic components. When a novel cationic surfactant, diglyceryl dodecyl dimethyl ammonium chloride(DGDAC), having the polyhydroxyl group at the hydrophilic head group, was mixed with a conventional anionic surfactant (sodium dodecyl sulfate; SDS) at equimolar ratio, we found that the aqueous equimolar mixture showed strong positive synergism in which molecular interaction parameter ${\beta}^M$ was very low, -17.2. According to the studies of equilibrium phase behavior and microscopy, this mixed system could form homogenous solutions containing vesicles.

• The Korean Journal of Nuclear Medicine
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• v.37 no.6
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• pp.418-427
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• 2003

Objects: $^{99m}-lactosylated$ human serum albumin (LSA) is a newly synthesized radiopharmaceutical that binds to asialoglycoprotein receptors, which are specifically presented on the hepatocyte membrane. Hepatic uptake and blood clearance of LSA were evaluated in rat with acute hepatic injury induced by dimethylnitrosamine (DMN) and results were compared with corresponding findings of liver enzyme profile and these of histologic changes. Materials and Methods: DMN (27 mg/kg) was injected intraperitoneally in Sprague-Dawley rat to induce acute hepatic injury. At 3(DMN-3), 8(DMN-8), and 21 (DMN-21) days after injection of DMN, LSA injected intravenously, and dynamic images of the liver and heart were recorded for 30 minutes. Time-activity curves of the heart and liver were generated from regions of interest drawn over liver and heart area. Degree of hepatic uptake and blood clearance of LSA were evaluated with visual interpretation and semiquantitative analysis using parameters (receptor index : LHL3 and index of blood clearance : HH3), analysis of time-activity curve was also performed with curve fitting using Prism program. Results: Visual assessment of LSA images revealed decreased hepatic uptake in DMN treated rat, compared to control group. In semiquantitative analysis, LHL3 was significantly lower in DMN treated rat group than control rat group (DMN-3: 0.842, DMN-8: 0.898, DMN-21: 0.91, Control: 0.96, p<0.05), whereas HH3 was significantly higher than control rat group (DMN-3: 0.731,.DMN-8: 0.654, DMN-21: 0.604, Control: 0.473, p<0.05). AST and ALT were significantly higher in DMN-3 group than those of control group. Centrilobular necrosis and infiltration of inflammatory cells were most prominent in DMN-3 group, and were decreased over time. Conclusion: The degree of hepatic uptake of LSA was inversely correlated with liver transaminase and degree of histologic liver injury in rat with acute hepatic injury.