• KSCE Journal of Civil and Environmental Engineering Research
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• v.8 no.1
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• pp.87-95
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• 1988

In the arctic offshore regions, massive offshore gravity platforms are recommended to be construced because of severe environments. In such structures which is so large that its characteristic length is of the order of the wave length, wave-structure interaction problem has been solved using linear diffraction theory. Structural analysis of the large scale offshore structures requires wave force distribution along depth and wave pressure distribution on the body surface. In this study, existing computer program which calculates the total wave force acting on axisymmetric bodies has been modified to calculate wave force distribution along depth and wave pressure distribution on the body surface. Numerical results of pressure distribution for a fixed vertical cylinder obtained from this analysis has been compared with the results of an analytic solution of MacCamy-Fuchs, and good agreements has been obtained. It is desirable to use 6 in the case of analytic solution, and 5 in the case of numerical solution as the Fourier Mode of Green function. The results in this study are expected to be utilized for structural analysis such as pseudo-static analysis, dynamic analysis and fatigue analysis.

• Journal of Biomedical Engineering Research
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• v.20 no.2
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• pp.173-182
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• 1999

Contrast-enhanced CT has an important role in assessing liver lesions, the optimal protocol to get most effective result is not clear. The mein goal when deciding injention protocol is to optimize lesion detectability with rapid scanning when lesion to liver contrast is maximum. For this purpose, we developed a physiological model of the contrast medium enhancement based on the compartment modeling and pharmacokinetics. Blood supply to liver is achieved in two paths. This dual supply characteristic distinguishes the CT enhancement of liver from that of the other organs. The first path is by hepatic artery and to second, by portal vein. However, it is assumed that only gepatic artery can supply blood to hepatocellular carcinoma(HCC) compartment, thus, the difference of contrast enhancement is resulted between normal liver tissue and hepatic tumor. By solving differential equations for each compartment simultaneously using the computer program Matlab, CT contrast-enhancement curves were simulated. The simulated enhancement curves for aortic, hepatic, portal vein, and HCC compartments were compared with the mean enhancement curves from 24 patients exposed to the same protocols as the simulation. These enhancement curves showed a good agreement. Furthermore, we simulated lesion-to-liver curves for various injection protocols, and the effects were analyzed. The variables to be considered in the injection protocol were injection rate, dose, and concentration of contrast material. These data may help to optimize scanning protocols for better diagnosis.