• Title/Summary/Keyword: Dynamic CT

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Myocardial Coverage and Radiation Dose in Dynamic Myocardial Perfusion Imaging Using Third-Generation Dual-Source CT

  • Masafumi Takafuji;Kakuya Kitagawa;Masaki Ishida;Yoshitaka Goto;Satoshi Nakamura;Naoki Nagasawa;Hajime Sakuma
    • Korean Journal of Radiology
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    • v.21 no.1
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    • pp.58-67
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    • 2020
  • Objective: Third-generation dual-source computed tomography (3rd-DSCT) allows dynamic myocardial CT perfusion imaging (dynamic CTP) with a 10.5-cm z-axis coverage. Although the increased radiation exposure associated with the 50% wider scan range compared to second-generation DSCT (2nd-DSCT) may be suppressed by using a tube voltage of 70 kV, it remains unclear whether image quality and the ability to quantify myocardial blood flow (MBF) can be maintained under these conditions. This study aimed to compare the image quality, estimated MBF, and radiation dose of dynamic CTP between 2ndDSCT and 3rd-DSCT and to evaluate whether a 10.5-cm coverage is suitable for dynamic CTP. Materials and Methods: We retrospectively analyzed 107 patients who underwent dynamic CTP using 2nd-DSCT at 80 kV (n = 54) or 3rd-DSCT at 70 kV (n = 53). Image quality, estimated MBF, radiation dose, and coverage of left ventricular (LV) myocardium were compared. Results: No significant differences were observed between 3rd-DSCT and 2nd-DSCT in contrast-to-noise ratio (37.4 ± 11.4 vs. 35.5 ± 11.2, p = 0.396). Effective radiation dose was lower with 3rd-DSCT (3.97 ± 0.92 mSv with a conversion factor of 0.017 mSv/mGy∙cm) compared to 2nd-DSCT (5.49 ± 1.36 mSv, p < 0.001). Incomplete coverage was more frequent with 2nd-DSCT than with 3rd-DSCT (1.9% [1/53] vs. 56% [30/54], p < 0.001). In propensity score-matched cohorts, MBF was comparable between 3rd-DSCT and 2nd-DSCT in non-ischemic (146.2 ± 26.5 vs. 157.5 ± 34.9 mL/min/100 g, p = 0.137) as well as ischemic myocardium (92.7 ± 21.1 vs. 90.9 ± 29.7 mL/min/100 g, p = 0.876). Conclusion: The radiation increase inherent to the widened z-axis coverage in 3rd-DSCT can be balanced by using a tube voltage of 70 kV without compromising image quality or MBF quantification. In dynamic CTP, a z-axis coverage of 10.5 cm is sufficient to achieve complete coverage of the LV myocardium in most patients.

Dynamic Computed Tomographic Characteristics of aColorectal Leiomyoma in a Dog (개에서 발생한 결장 평활근종에 대한 동적 컴퓨터 단층촬영 소견 1례)

  • Park, Noh-Won;Chung, Wook-Hun;Han, Jae-Woong;Eom, Ki-Dong
    • Journal of Veterinary Clinics
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    • v.32 no.2
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    • pp.200-204
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    • 2015
  • A 12-year-old neutered male Shih Tzu presented with constipation and dyschezia. Abdominal radiographs showed distension of the descending colon and dorsal compression of the colon by a soft tissue mass. The mass was well-marginated with homogeneous soft tissue attenuation and showed no evidence of metastasis on computed tomography (CT). The dynamic CT showed a consistently mild contrast enhancement. The perfusion and capillary permeability were lower than those of the gluteal muscle. The tentative imaging diagnosis was a benign intrapelvic tumor, which rarely shows angiogenesis. The mass was excised, and a leiomyoma was confirmed by histopathologic examination.

Quantitative Assessment of Salivary Gland washout in Clinically Healthy Dogs

  • Jang, Won-seok;Hwang, Tae-sung;Jung, Dong-in;Lee, Jae-hoon;Lee, Hee-chun
    • Journal of Veterinary Clinics
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    • v.37 no.1
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    • pp.28-33
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    • 2020
  • The aims of this study were to obtain the normal ranges of enhancement parameters for salivary gland in dynamic CT and to investigate the effects of fasting time on contrast enhancement in clinically normal beagle dogs. With five healthy beagle dogs, dynamic CT examination was performed according to fasting times (as fasting times, 12hours, 0 min, 20 min, 40 min, 1 hours, 6 hours, 24 hours). In normal beagles with 12hours fasting, enhancement parameters through the preliminary study were as follows: ImaxA - 472 .49 ± 19.01 HU; ImaxS - 138.95 ± 6.2 5 HU; TmaxA - 25.8 ± 1.79 sec; TmaxS - 69.0 ± 23.11 sec; Teq - 80.5 ± 6.61 sec; T-Aeq - 54.5 ± 5.51 sec (Imax - peak enhancement; Tmax - time to peak enhancement; Teq - time to equilibrium phase; T-Aeq - time between peak enhancement in the common carotid artery and onset of the equilibrium phase; A - common carotid; S - submandibular gland; HU - Hounsfield unit). Additionally, ImaxA and ImaxS were significantly increased in 40 min after eating. Because these results associated with postprandial hemodynamic changes can make the diagnosis of salivary gland diseases more difficult, sufficient fasting time is important for accurate diagnosis.

Lung cancer and insurance medicine (폐암과 보험의학)

  • Lee, Sin-Hyung
    • The Journal of the Korean life insurance medical association
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    • v.31 no.1
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    • pp.34-36
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    • 2012
  • Lung cancer such as small cell lung cancer(SCLC) and non small cell lung cancer(NSCLC) have high mortality rate, so, we insurance doctors have little interest in their risk. But nowadays there's a lot of development in targeted therapy of NSCLC. Screening by CT scanning and early resection strategy also shows better prognosis. It is helpful for underwriters and insurance doctors to review the current development of targeted therapy of NSCLC and estimation of extra-risk of early lung cancer. The preferred treatment option for patients whose tumors contain EGFR-activating mutations are one of the EGFR-directed tyrosine kinase inhibitors, such as gefitinib or erlotinib. In patients with NSCLC whose tumors harboured an ALK rearrangement, there was 61% objective response rate to crizotinib in the phase 1 study. The median survival progression-free survival was 10 months. Mortality analysis of early lung cancer who were detected by CT screening, MR of 105% and EDR of 1‰ were calculated.

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Realtime 3D Reconstruction of the Surface on Cross Sectional Contour in CT Image (단면 윤곽선을 이용한 표면의 실시간 3차원 재구성)

  • Koo, J.Y.;Jung, S.B.;Min, H.G.;Hong, S.H.
    • Proceedings of the KOSOMBE Conference
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    • v.1998 no.11
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    • pp.189-190
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    • 1998
  • In this paper, we show the realtime 3D reconstruction algorithm with the sliced CT images. The preprocessing is thresholding, labeling, contouring, and extracting dominant point. we reconstruct 3D image with dominant points using dynamic matching technique. The software implemented in Visualc++ 5.0 as a window-based application program.

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Analysis and Design of a New Topology of Soft-Switching Inverters

  • Chen, Rong;Zhang, Jia-Sheng
    • Journal of Power Electronics
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    • v.13 no.1
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    • pp.51-58
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    • 2013
  • This paper proposes the power conversion mechanism of a bailer-charge-transfer zero-current-switching (CT-ZCS) circuit. The operation modes are analyzed and researched using state trajectory equations. The topology of CT-ZCS based on soft-switching inverters offers some merits such as: tracking the input reference signal dynamically, bearing load shock and short circuit, multiplying inverter N+1 redundancy parallel, coordinating power balance for easy control, and soft-switching commutation for high efficiency and large capacity. These advantages are distinctive from conventional inverter topologies and are especially demanded in AC drives: new energy generation and grid, distributed generation systems, switching power amplifier, active power filter, and reactive power compensation and so on. Prototype is manufactured and experiment results show the feasibility and dynamic voltage-tracking characteristics of the topology.

Experimental Study on Deformation and Failure Behavior of Limestones under Dynamic Loadings (동적하중 하에서 석회암의 변형 및 파괴거동에 관한 실험적 연구)

  • Kang, Myoung-Soo;Kang, Hyeong-Min;Kim, Seung-Kon;Cheon, Dae-Sung;Kaneko, Katsuhiko;Cho, Sang-Ho
    • Tunnel and Underground Space
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    • v.22 no.5
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    • pp.339-345
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    • 2012
  • Information on the deformation behavior and fracture strength of rocks subjected to dynamic loadings is important to stability analyses of underground openings underground vibration due to rock blasts, earthquakes and rock bursts. In this study, Split Hopkinson Pressure Bar (SHPB) system was applied to estimate dynamic compressive and tensile fracture strengths of limestone and also examine deformation behavior of limestones under dynamic loadings. A micro-focus X-ray CT scanner was used to observe non-destructively inside the impacted limestone specimens. From the dynamic tests, it was revealed that the limestone have over 140MPa dynamic compressive strength and the strain-rate dependency of the strength. Dynamic Brazilian tensile strength of the limestone exceeds 21MPa and shows over 3 times static Brazilian tensile strength.

Measurement of Variation in Water Equivalent Path Length by Respiratory Organ Movement

  • Minohara, Shinichi;Kanai, Tatsuaki;Endo, Masahiro;Kato, Hirotoshi;Miyamoto, Tadaaki;Tsujii, Hirohiko
    • Proceedings of the Korean Society of Medical Physics Conference
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    • 2002.09a
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    • pp.90-93
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    • 2002
  • In particle radiotherapy, a shape of the beam to conform the irradiation field is statically defined by the compensator, collimator and potal devices at the outside of the patient body. However the target such as lung or liver cancer moves along with respiration. This increases the irradiated volume of normal tissue. Prior discussions about organ motions along with respiration have been mainly focused on inferior-superior movement that was usually perpendicular to beam axis. On the other hand, the change of the target depth along the beam axis is very important especially in particle radiotherapy, because the range end of beam (Bragg peak) is so sharp as to be matched to distal edge of the target. In treatment planning, the range of the particle beam inside the body is calculated using a calibration curve relating CT number and water equivalent path length (WEL) to correct the inhomogeneities of tissues. The variation in CT number along the beam path would cause the uncertainties of range calculation at treatment planning for particle radiotherapy. To estimate the uncertainties of the range calculation associated with patient breathing, we proposed the method using sequential CT images with respiration waveform, and analyzed organ motions and WELs at patients that had lung or liver cancer. The variation of the depth along the beam path was presented in WEL rather than geometrical length. In analyzed cases, WELs around the diaphragm were remarkably changed depending on the respiration, and the magnitude of these WEL variations was almost comparable to inferior-superior movement of diaphragm. The variation of WEL around the lung was influenced by heartbeat.

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A Study on the ballistic impact resistance and dynamic failure behavior of aramid FRMLs by high velocity impact (고속충격에 의한 아라미드 섬유강화 금속적층재의 방탄성능 및 동적파손거동에 관한 연구)

  • 손세원;이두성;김동훈;홍성희
    • Proceedings of the Korean Society of Precision Engineering Conference
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    • 2000.11a
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    • pp.527-532
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    • 2000
  • The armor composite material targets such as aramid FRMLs with different type and ply number of face material and different type of back-up material, were studied to determine ballistic impact resistance and dynamic failure behavior during ballistic impact. Ballistic impact resistance is determined by $\textrm{V}_{50}$ ballistic limit, a statical velocity with 50% probability for complete penetration, test method. Also dynamic failure behaviors are respectfully observed that result from $\textrm{V}_{50}$ tests. $\textrm{V}_{50}$ tests with $0^{\circ}$ obliquity at room temperature were conducted with projectiles that were able to achieve near or complete penetration during high velocity impact tests. As a result, ballistic impact resistance of anodized Al 5052-H34 alloy(2 ply) is better than that of anodized Al 5052-H34 alloy(1 ply), but Titanium alloy showed the similar ballistic impact resistance. In the face material, ballistic impact resistance of titanium alloy is better than that of anodized Al 5052-H34 alloy. In the back-up material, ballistic impact resistance of T750 type aramid fiber is better than that of CT709 type aramid fiber.

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Radiologic Findings of Renal Oncocytomas (신장 호산성과립세포종의 영상의학적 소견)

  • Cho, Jae-Ho
    • Journal of Yeungnam Medical Science
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    • v.26 no.1
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    • pp.30-37
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    • 2009
  • Purpose : To radiologically differentiate renal oncocytoma from other renal solid tumors, we analyzed and characterized, retrogradely, radiologic findings of renal oncocytomas. Materials and Methods : Radiologic findings of pathologically proven renal oncocytoma were analyzed in 9 patients. CT was performed in all patients, ultrasonography in 4 patients and MRI in 3 patients.(51) Results : On ultrasonography, the echogenicity of the mass was slightly more hyperechoic than normal renal parenchyma in all 4 cases. Two cases were homogeneous and the remaining two cases were relatively homogeneous. On CT, all 8 cases showed iso-density to slightly low density compared to normal renal parenchyma and 5 cases were homogeneous but the central portion of the mass was of a slightly lower density than the peripheral portion in 3 cases. All six cases had an arterial phase scan and were heterogeneously enhanced. An irregular, lower-enhancing portion was found in the central portion of the mass. Segmental inversion of contrast enhancement was found in 5 of 6 cases that had a dynamic enhancement study. On MR T1-weighted imaging, the mass was of iso-signal intensity to normal renal parenchyma and the central portion of the mass had a slightly hypo-signal intensity than the peripheral portion. On T2-weighted imaging, 2 cases were heterogeneous; the peripheral portion was of low signal intensity and central portion was of higher signal intensity than normal renal parenchyma. One case was relatively homogeneous and showed a slightly lower signal intensity than that of normal parenchyma, except for a central small portion showing high signal intensity. For 2 cases that had a dynamic study, a segmental inversion of contrast enhancement was noted. Conclusion : Renal oncocytoma is seen as a well-marginated solid mass lesion. On enhanced scans it is heterogeneously enhanced and segmental inversion of contrast enhancement may be seen. The possibility of oncocytoma can be suggested in cases showing these radiologic findings.

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