• Journal of Radiopharmaceuticals and Molecular Probes
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• v.5 no.2
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• pp.89-100
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• 2019

In our previous studies, we developed a ¹⁸F-labeled TSPO-binding ligand, named [¹⁸F]CB251, which has been proved to be a promising TSPO-binding PET radiotracer for the detection and monitoring of TSPO expression in pathological diseases. (Ki = 0.27 nM for TSPO, 1.96% ID/g of tumor uptake at 1h post-injection) Based on these results, we utilized 6,8-dichloro-2-phenylimidazo[1,2-a]pyridineacetamide analogs, CB185 (1) as a targeting moiety for the selective delivery of probes and anticancer molecules to TSPO-overexpressed tissues. In this study, we designed CB185 derivatives contains different PEG chains (n = 1, 3 and 5) and fluorescence dye (Cy5) to identify the necessary space between a TSPO-binding ligand and an anticancer agent. Three CB185 derivatives (11a-c) which contains Cy5 and PEG chain, were synthesized and the effect of PEG additive on their TSPO-binding affinities were evaluated using in vitro assays. The binding affinity for compounds 11a-c was lower than that of PK11195 (Ki = 3.2 nM), but still characterized by nanomolar binding affinity for TSPO (Ki = 46.5 nM for 11a, 51.0 nM for 11b, and 388.5 nM for 11c). These results showed that the conjugates are characterized by a moderate binding affinity toward TSPO except for compound 11c, which PEG chain consist of five PEG monomers. Our finding might add useful information to decide the appropriate PET chain length for developing new TSPO-targeting drug carriers.

• Textile Coloration and Finishing
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• v.14 no.1
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• pp.51-57
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• 2002

In the prior study, the mechanical properties and the dyeability of the easily dyeable polyester grim(EDY) were investigated. In this study, to interpret the dyeing behavior of EDY with C. I. Disperse Violet 1, the thermodynamic parameters of dyeing, such as the standard affinity, the heat of dyeing(the enthalpy change), the entropy change, the diffusion coefficient, and the activation energy of diffusion, were obtained from adsorption isotherms and dyeing rate at various temperatures and compared to these of regular polyester (REG-PET). The heat of dyeing(the enthalpy change) and the entropy change for EDY showed smaller negative values than those for REG-PET. This means that the dye molecules in the EDY are combined more loosely than in the REG-PET and that is due to the flexibility of polymer chains of EDY. The diffusion coefficients of C. I. Disperse Violet 1 into the EDY were larger than those for REG-PET, and the activation energy of diffusion on EDY was smaller than that on REG-PET.

• Proceedings of the Korean Society of Dyers and Finishers Conference
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• 2012.03a
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• pp.29-29
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• 2012

Rhodamine chromophore/fluorophore have been attracted to many researchers due to its excellent photophysical properties. In this study, we have designed and synthesized a strong emissive fluorescent dye chemosensor for toxic elements. A rhodamine-based sensor was prepared by incorporation the rhodamine fluorophore and several functional host groups with high affinity to hazardous metal and anion. This sensor shows a high selectivity and an excellent sensitivity and is a dual-responsive colorimetric and fluorescent metal/anion-specific sensor. In addition, the 1:1 binding mode was proposed based on Job's plot method. Finally, computational calculation was simulated and calculated to approach for HOMO/LUMO of this dye chemosensor.

• Korean Journal of Human Ecology
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• v.19 no.4
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• pp.709-717
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• 2010

This study investigated the properties and functions of wool and silk dyed with Catechu by examining the effects of dying conditions such as dye concentration, dying temperature, dyeing time, pH level and pre-mordants. These conditions were examined in relation to dye uptake and color changes, washing fastness, light fastness, ultraviolet-cut ability and antimicrobial ability of the dyed fabrics. Catechu showed good affinity to silk fiber. Langmuir adsorption isotherm was obtained, and so it was considered that ionic bondings are formed between Catechu and protein fiber. As the dyeing time and temperature is increased, the dyeability of both silk and wool fabrics also increases. At high temperatures the color of dyed fabrics changes from Y and YR to R. Wool is effective in using Al, Cu, Fe mordant, while silk is effective only in using only Cu mordants. The dyeability was shown to be improved at low pH levels. Additionally, both washing fastness and light fastness were shown to be low. However, the fabric color gradually changed to red was due to mailard reaction of catechol tannin causingby repeated washing and sunlight. The ultraviolet-cut ability was improved for cotton fabric dyed with Catechu. Also, dyed fabric with Catechu showed very good antimicrobial abilities at 99.9%.

• Journal of the Korean Society of Clothing and Textiles
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• v.18 no.3
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• pp.287-297
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• 1994

The purpose of this study is to investigate the Improvement of fiber surface, tenacity & elogation, fabric counts, thickness, handle, moisture regain, static voltage, handle, dyeability when polyester fabrics are treated with NaOH solution adding quartemary ammonium salt (Benzyl dimetyl dodecyl ammonium chloride . BDMDAC) The results are as follows. I. In regard to the method of processing VET, when the PET fabrics are alkaline-hydrolyzed adding BDMDAC, the weight loss of PET fabrics increased remarkably to the increse of BDMDAC concentration than when they are treated only in NaOH solution. When PET fabrics are alkaline-hydrolyzed the amount of BDMDAC as the catalyst is proper lg/1 II. The change in physical & chemical properties of alkaline-hydrolyzed PET fabrirs. 1. As the amount of the weight loss on PET fabrics increased, the void space of the PET yale increased but tenacity & elongation and thickness decreased. 2. The fabric counts of PET increased due to shrinkage by alkaline-hydrolydzing. 3. As the amount of of the weight loss on PET fabrics increased. NUMERI, FUKURAMI, increaseed and KOSHI decreased and Total hand value(T.H.V) in all cases increaseed. When the weight Ioss is 30.9% T.H.V. is best. 4. Moisture regain of PET fabrics a little increased by alkaline-hydrolyzing treatment. As the weight loss increased, static voltage is decreased. 5. The last dye absorption is different according to the degree of the Affinity. In regard to the difference of dye color, the dyestuff of low molecular weight dyed for deep color.

• Journal of the Korea Fashion and Costume Design Association
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• v.8 no.1
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• pp.49-57
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• 2006

Turmeric is aromatic, perennial herb, up to 1m high and distributed in East Asia. Parts used of it Rhizomes and is known to be used a medicinal stuff yellow dye stuff from past to nowadays in the Oriental region. The objectives of this study were to investigate and to compare to the dyeability of Turmeric according to pH, temperature, mordants, and the antimicrobial properties of wool dyed with turmeric. The results of this study are as follows: The wavelengths of the strongest absorption of Turmeric extract were 420 nm respectively. The extracted dye from Turmeric has affinity to wool. The dyeing rates are decreased according to diluting times and the dyeing rates are increased according to high temperature. The color of pH 3-7 is yellow green, over pH 9 is turned to orange yellow. The color of the non-mordant sample is yellow but it changed to bright yellow by Al, to orange yellow by Cu mordant, and to brown yellow by Fe mordant. The launder fastness and is not good, 2-4 grade and the light fastness is bad, 2-3 grade, but the dry-cleaning fastness is generally good, 4-5 grade. The fabrics dyed with Turmeric extract showed high antibacterial property on Staphylococcus aureus.

• Textile Coloration and Finishing
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• v.24 no.1
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• pp.8-17
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• 2012

In order to dye nylon/cotton blended fabrics in solid colors with only acid dyes, a hetero-bifunctional bridge compound (DBDCBS) was examined. The bridge compound was designed to react only onto cotton fabrics first, on which amino-containing acid dyes react later by covalent bonding. By the effect of DBDCBS, amino-containing acid dyes exhibited high affinity toward the cotton fabrics. From the dyeing properties examined at various conditions, the optimum dyeing was decided at pH 4 and $100^{\circ}C$. Consequently, the solid color was obtained on nylon/cotton blended fabrics in one bath dyeing process using only acid dyes. The DBDCBS did not show any negative effect on nylon side in terms of dyeing and physical properties.

• Journal of the Korean Society of Clothing and Textiles
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• v.26 no.3_4
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• pp.422-430
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• 2002

Dyeing properties of the colorants from gromwell on cotton fabric were investigated. The effects of dyeing conditions on dye uptake and the effects of mordants and mordanting methods on K/S value, color change and colorfastness were explored. Gromwell colorants showed low affinity to cotton fabric, and its adsorption isotherm was Freundlich type close to Langmuir type. Therefore, it was considered that hydrogen bonding and Vander Waals force were involved in the adsorption of gromwell colorants to cotton fabric. Pre-mordanting method except Sn mordant gave higher K/S value but it was not significant. Gromwell colorants produced mainly R and RP color on cotton fabric depending on mordants and mordanting method. Dyed cotton fabric showed generally high colorfastness irrespective of mordanting treatment. Light colorfastness was increased by repeat dyeing and Fe and Sn mordanting.

• Journal of the Korean Society of Clothing and Textiles
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• v.28 no.12 s.138
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• pp.1625-1631
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• 2004

The purpose of this study was to investigate dyeing properties of cotton fabrics by American fleabane extract. Effect of dyeing condition on dye uptake and effect of mordanting on dye uptake, color change and colorfastness were explored. Its affinity to cotton fiber was considerably lower than wool, and its hydrogen bonding was involved in the absorption of American fleabane colorants to cotton fiber. K/S value of pre­mordanting was higher than sim-mordanting or post-mordanting. Except that Sn mordanted showed high K/S value, it did not significantly increase. American fleabane produced mainly yellowish color on mordants and mordanting method. Cotton fabrics showed generally high colorfastness except colorfastness to washing.

• Restorative Dentistry and Endodontics
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• v.20 no.1
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• pp.152-163
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• 1995

This experiment was performed to observe the adhesion pattern and microleakage in the gingival margin according to variation in the resin cement thickness which results from thickness of Die spacer. which is considered to effect the adaptability of the composite resin inlays. Clearfil CR inlays were fabricated on stone models with CR Sep applicated once and Nice fit twice, 4 times, and 6 times each. After 2nd curing within the CRC-100 oven, CR inlays were cemented with CR inlay cement. Dye(2% methylene blue) penetration and adhesion pattern were evaluated after sectioning of gingival margin into :3 pieces. The results were as follows ; 1. The thickness of resin cement showed unevenchanging pattern with that of die spacer, namely, it was increased until 4 times' application of Nice-Fit but was decreased with 6 times' application of that. 2. The degree of dye penetration wasn't affected by cement thickness within a limited value. 3. Most of dye penetration was shown through the interface between cement and enamel rather than the interface between cement and CR inlay. This shows that the affinity of resin cement for CR inlay was superior to the adhesive strength with tooth structure. 4. No gap was found at the interface between enamel and cement but some showed separation between dentin and cement. It is concidered that the contraction force of cement was less than the bond strength with the enamel. 5. Lots of voids were found in the CR inlay and resin cement. There was a pooling tendency of bonding agent and cement in the axiogingival line angle portion. 6. In some specimens, cracks were shown in enamel margin. From this it could be considered that cavity preparation and surface treatment weakened the tooth structure.