• The Korean Journal of Applied Statistics
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• v.24 no.6
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• pp.1077-1094
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• 2011

We accomplish clustering analyses for yeast cell cycle microarray expression data. To reflect the characteristics of a time-course data, we screen the genes using the test statistics with Fourier coefficients applying a FDR procedure. We compare the results done by model-based clustering, K-means, PAM, SOM, hierarchical Ward method and Fuzzy method with the yeast data. As the validity measure for clustering results, connectivity, Dunn index and silhouette values are computed and compared. A biological interpretation with GO analysis is also included.

• Journal of the Korean Data and Information Science Society
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• v.22 no.4
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• pp.741-753
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• 2011

We accomplish clustering analyses for yeast cell cycle microarray expression data. We compare model-based clustering, K-means, PAM, SOM and hierarchical Ward method with yeast data. As the validity measure for clustering results, connectivity, Dunn Index and silhouette values are computed and compared.

• The Korean Journal of Applied Statistics
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• v.20 no.1
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• pp.167-181
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• 2007

Many clustering algorithms and cluster validation techniques for high-dimensional gene expression data have been suggested. The evaluations of these cluster validation techniques have, however, seldom been implemented. In this paper we compared various cluster validity indices for low-dimensional simulation data and real gene expression data, and found that Dunn's index is the most effective and robust, Silhouette index is next and Davies-Bouldin index is the bottom among the internal measures. Jaccard index is much more effective than Goodman-Kruskal index and adjusted Rand index among the external measures.

• The Korean Journal of Applied Statistics
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• v.22 no.4
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• pp.745-758
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• 2009

Cluster analysis is the automated search for groups of related observations in a data set. To group the observations into clusters many techniques has been proposed, and a variety measures aimed at validating the results of a cluster analysis have been suggested. In this paper, we compare complete linkage, Ward's method, K-means and model-based clustering and compute validity measures such as connectivity, Dunn Index and silhouette with simulated data from multivariate distributions. We also select a clustering algorithm and determine the number of clusters of Korean consumers based on Korean consumers' palatability scores for Hanwoo bull in BBQ cooking method.

• Journal of Korean Society for Geospatial Information Science
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• v.22 no.4
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• pp.175-181
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• 2014

Korean government proposed a new initiative 'government 3.0' with which the administration will open its dataset to the public before requests. City of Seoul is the front runner in disclosure of government data. If we know what kind of attributes are governing factors for any given segmentation, these outcomes can be applied to real world problems of marketing and business strategy, and administrative decision makings. However, with respect to city of Seoul, selection of optimal variables from the open dataset up to several thousands of attributes would require a humongous amount of computation time because it might require a combinatorial optimization while maximizing dissimilarity measures between clusters. In this study, we acquired 718 attribute dataset from Statistics Korea and conducted an analysis to select the most suitable variables, which differentiate Gangnam from other districts, using the Genetic algorithm and Dunn's index. Also, we utilized the Microsoft Azure cloud computing system to speed up the process time. As the result, the optimal 28 variables were finally selected, and the validation result showed that those 28 variables effectively group the Gangnam from other districts using the Ward's minimum variance and K-means algorithm.

• Communications for Statistical Applications and Methods
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• v.27 no.6
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• pp.589-602
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• 2020

The development of smart grids has enabled the easy collection of a large amount of power data. There are some common patterns that make it useful to cluster power consumption patterns when analyzing s power big data. In this paper, clustering analysis is based on distance functions for time series and clustering algorithms to discover patterns for power consumption data. In clustering, we use 10 distance measures to find the clusters that consider the characteristics of time series data. A simulation study is done to compare the distance measures for clustering. Cluster validity measures are also calculated and compared such as error rate, similarity index, Dunn index and silhouette values. Real power consumption data are used for clustering, with five distance measures whose performances are better than others in the simulation.

• Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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• v.35 no.5
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• pp.415-422
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• 2017

Finding influential factors from given clustering result is a typical data science problem. Genetic Algorithm based method is proposed to derive influential factors and its performance is compared with two conventional methods, Classification and Regression Tree (CART) and Chi-Squared Automatic Interaction Detection (CHAID), by using Dunn's index measure. To extract the influential factors of preference towards political parties in South Korea, the vote result of $18^{th}$ presidential election and 'Demographic', 'Health and Welfare', 'Economic' and 'Business' related data were used. Based on the analysis, reverse engineering was implemented. Implementation of reverse engineering based approach for influential factor analysis can provide new set of influential variables which can present new insight towards the data mining field.

• 한국데이터정보과학회:학술대회논문집
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• 2006.04a
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• pp.63-76
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• 2006

Several clustering algorithms to analyze gene expression data and cluster validation techniques that assess the quality of their outcomes, have been suggested, but evaluations of these cluster validation techniques have seldom been implemented. In this paper we compared various cluster validity indices for simulation data and real genomic data, and found that Dunn's index is more effective and robust through small simulations and with real gene expression data.

• Proceedings of the Korean Society for Bioinformatics Conference
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• 2003.10a
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• pp.26-51
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• 2003

Large scale protein interaction maps provide a new, global perspective with which to analyse protein function. PSIMAP, the Protein Structural Interactome Map, is a database of all the structurally observed interactions between superfamilies of protein domains with known three-dimensional structure in thePDB. PSIMAP incorporates both functional and evolutionary information into a single network. It makes it possible to age protein domains in terms of taxonomic diversity, interaction and function. One consequence of it is to predict the most important protein domain structure in evolution. We present a global analysis of PSIMAP using several distinct network measures relating to centrality, interactivity, fault-tolerance, and taxonomic diversity. We found the following results: ${\bullet}$ Centrality: we show that the center and barycenter of PSIMAP do not coincide, and that the superfamilies forming the barycenter relate to very general functions, while those constituting the center relate to enzymatic activity. ${\bullet}$ Interactivity: we identify the P-loop and immunoglobulin superfamilies as the most highly interactive. We successfully use connectivity and cluster index, which characterise the connectivity of a superfamily's neighbourhood, to discover superfamilies of complex I and II. This is particularly significant as the structure of complex I is not yet solved. ${\bullet}$ Taxonomic diversity: we found that highly interactive superfamilies are in general taxonomically very diverse and are thus amongst the oldest. This led to the prediction of the oldest and most important protein domain in evolution of lift. ${\bullet}$ Fault-tolerance: we found that the network is very robust as for the majority of superfamilies removal from the network will not break up the network. Overall, we can single out the P-loop containing nucleotide triphosphate hydrolases superfamily as it is the most highly connected and has the highest taxonomic diversity. In addition, this superfamily has the highest interaction rank, is the barycenter of the network (it has the shortest average path to every other superfamily in the network), and is an articulation vertex, whose removal will disconnect the network. More generally, we conclude that the graph-theoretic and taxonomic analysis of PSIMAP is an important step towards the understanding of protein function and could be an important tool for tracing the evolution of life at the molecular level.