• Title/Summary/Keyword: Drug Reduction

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Effect of Aquatic Exercise Program on Lower Limbs, Muscle Strength, Knee Joint Flexion and Pain Changes of Arthritis Patients (수중운동이 관절염 환자의 하지근력, 관절각도 및 통증에 미치는 영향)

  • Lee, Young-Ok;Choi, Myung-Han;Kim, Jong-Im;Lee, Tae-Yong
    • Journal of muscle and joint health
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    • v.5 no.2
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    • pp.222-237
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    • 1998
  • In an attempt to investigate the effect of long-term aquatic exercise program on lower limbs' muscle strength, knee Joint flexion, pain reduction and weight changes with aquatic exercise program. Forty three women with arthritis were pre and post tested for changes of muscle strength, range of motion, weight and pain. This data was collected from April 1, 1997 to February 24, 1998. The mean age was 52.5. Statistically significant in lower limbs' muscle strength with an aquatic exercise program by age, BMI, education, rheumatic drug use, illness duration until 12 weeks after experiment. Statistically significant in knee joint flexion with aquatic exercise program by age, BMI, education, rheumatic drug use, illness duration until 12 weeks after experiment. Statistically significant in pain reduction with aquatic exercise program by age, BMI, education, rheumatic drug use, illness duration until 12 weeks after experiment. Statistically significant in weight changes with aquatic exercise program by age, BMI, education, rheumatic drug use, illness duration until 6 weeks after experiment. As a conclusion, aquatic exercise programs for the patients with arthritis require at least 12 weeks and a variety of aquatic exercise programs for the effective control should be developed.

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Anthelmintic Efficiency of Nitroxynil against Fasciola hepatica, Eurythrema Pancreaticum and Paramphistomum sp. in Korean Native Goat (재래흑산양(在來黑山羊)의 흡충류(吸蟲類)(간질(肝蛭), 췌질(膵蛭), 쌍구흡충(雙口吸蟲))에 대(對)한 Nitroxynil(Trodax)의 구충효과(驅蟲效果))

  • Suh, Myung-Deuk
    • Korean Journal of Veterinary Research
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    • v.23 no.2
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    • pp.199-203
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    • 1983
  • The anthelmintic efficiency of nitroxynil(Trodax) at a dose rate of 10mg/kg was tested in naturally infected Korean native goat (Black goat) against Fasciola hepatica, Eurythrema pancreaticum, and Paramphistomum sp. The drug was administered with injection subcutaneouslly and the efficiency was measured by faecal examination microscopically. The results obtained were summarized as follows: 1. The anthelmintic efficiency of nitroxynil against Fasciola hepatica was shown 33.3% on day 7, 88.9% on day 14 and 94.4% on day 28 after the administration of the drug, respectively. The reduction rates of egg per gram of faeces (E. P. G.) against Fasciola hepatica in faecal examination were shown 86.8% on day 7, 97.7% on day 14, and 99.7% on day 28 postmedication. 2. The anthelmintic efficiency of nitroxynil against Paramphistomum sp. was shown 0% on day 7, 10.5% on day 14, and 36.8% on day 28 after the administration of drug. The reduction rates of E. P. G. against the parasite were shown 13.2% on day 14, and 39.4% on day 28 postmedication. 3. The anthelmintic efficiency of nitroxynil against Eurythrema pancreaticum was shown 0% on day 7, 16.6% on day 14, and 25% on day 28 after the administration of the drug.

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Factors associated with changes in pharmaceutical expenditures of outpatient care in clinic setting : Focusing on the incentive scheme to reduce total prescribed drug expenditure and the drug utilization review system (의원 외래환자의 약품비 변화 관련요인: 처방총액 절감 인센티브제도와 DUR 제도 시행 전후를 중심으로)

  • Yi, Myung-Hyun;Chung, Woojin;Cho, Eun;Kim, Roeul;Lee, Sunmi
    • Health Policy and Management
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    • v.22 no.4
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    • pp.561-578
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    • 2012
  • This study was performed in order to compare a change in pharmaceutical expenditures per outpatient of clinic and to analyze factors relevant to a systems as part of evaluating policies for the incentive scheme to reduce total prescribed drug expenditure and for the drug utilization review system("DUR system" hereafter). For this, it had finally analytical subjects as 21,320 clinics nationwide without a change in location, clinics symbol and signed subject during both terms of the first half of 2010 and the first half of 2011. As a result, the odds ratio with reduction in pharmaceutical expenditures of clinic was statistically higher significantly in the shorter year number of opening clinic, in the larger number of doctors, when the classification of establishment is other, not individual, and when the signed subject is surgical division. Also, the odds ratio was significantly higher in the less patient number of clinic and in the lower ratio of patients aged over 65. Finally, the odds ratio was significantly high when a clinic had been located in DUR system demonstrative project area. Through this, a case of policy for improvement in doctor's autonomous prescription behavior like DUR system can be known to be effective for reduction in pharmaceutical expenditures. A future research on evaluation of policy for pharmaceutical expenditure management system will need to be performed in-depth analysis in consideration of diverse characteristics on the participatory entities.

A study on effect related to health industry through WTO entrance of China (중국(中國) WTO 가입(加入) 및 관세인하(關稅引下)에 따른 4개 분야(分野) 보건산업(保健産業) 수출(輸出)에 대한 연구(硏究))

  • Kim, Jong-Kwon
    • THE INTERNATIONAL COMMERCE & LAW REVIEW
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    • v.27
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    • pp.165-181
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    • 2005
  • The health industry of China is faster than before, so it will be rank 5th at world-wide markets in 2010. Firstly, the custom tariff was lower at 15% in 2000 and at 10.4% on June 2005. And, it will be lower into 9.8% in 2010. Secondly, this is because of expansion of purchase power on increase in economic growth, extended human life expectancy. As it is entered the WTO in January 2002, it will positively affect on export of Korea for China. This paper focuses on the analysis of export increase caused by reduction of custom tariff in China. As above mentioned, the time schedule on average reduction of custom tariff was 15% in 2000, 10.4% in 2005. Then, it will be lower into 9.8% in 2010. As the empirical test related health industry, it presents 19.80% export increase rate for China of Korea on reduction of custom tariff from 2001 to 2010. The exporting of drug for China will be up to 17.85% for 10 years. Also, the exporting of Biomedical will be up to 20.99%, and respectively 22.95%, 22.60% in Cosmetics and food industry. Conclusionally, the exporting of this health industry will be increase greatly, compared with any other industries. So, it is necessary that firms increase in R&D investment and government support as policy for health industry.

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Dietary Self-Efficacy and Dietary Behaviors by Eating Areas according to Perceived Dietary Habit Levels related to Sodium Intake (나트륨 섭취 인지수준에 따른 식사 장소별 식행동 및 식이 자아효능감)

  • Yeon, Jee-Young;Kwon, Kwang-Il;Kim, Jong-Wook;Park, Hye-Kyung
    • The Korean Journal of Food And Nutrition
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    • v.30 no.1
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    • pp.166-174
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    • 2017
  • The purpose of this study was to compare dietary self-efficacy for sodium intake reduction and dietary behaviors by eating areas. Subjects (797 males and 767 females) were classified according to perceived dietary habit levels related to sodium intake (lowest: ${\leq}10$ (n=434), low: $11{\sim}{\leq}13$ (n=471), high: $14{\sim}{\leq}15$ (n=360), highest: $16{\leq}$ (n=299)) using an online survey with a sample that was geographically representative of the population. The highest group was significantly younger and had a higher student proportion than the lowest group. Dining contexts regarding home led to a significantly higher sodium intake in the highest group, but it was eating out for the lowest group. The highest group had a significantly lower intention to reduce sodium intake compared to the lowest group. In the home cooked meals, the highest group displayed a significantly lower cooking frequency, less effort with respect to a low sodium diet and cooking habits related to sodium intake as compared to the lowest group. Also, regarding eating out and food service, the highest group exhibited significantly lower efforts and dietary behaviors to reduce sodium intake than the lowest group. The dietary score for sodium reduction behavior in the highest group was significantly lower compared to the lowest group, for home cooked meals, eating out, as well as food service. Thus, dietary guidelines and nutrition education for the reduction of sodium intake by eating areas need to be developed and provided.

A Study on the Actual Condition of Drug Abuse by Some Juveniles in Seoul - Based on Third School Year Students of Some Senior High Schools - (서울 시내 일부 청소년의 약물남용 실태에 관한 조사 연구 - 고등학교 3학년 학생을 중심으로 -)

  • Koh, Hong-Kyeong;Kim, Myung
    • Korean Journal of Health Education and Promotion
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    • v.7 no.1
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    • pp.72-82
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    • 1990
  • The actual condition of drug abuse by some Juveniles in our country and effects of some elements on their drug abusing were observed providing basic materials for health education to juveniles to contribute to the health improvement of them and the reduction of the harmfulness of drug abuse. 1035 third school year students of some senior high schools in Seoul were subjected to the questionnaire survey. The results could be summarized as follows : 1. Among the twelve kinds of drug involved in the study, alcohol (72.0%), cigarette (44.2%), stimulants (23.9%), analgesics (7.9%) appeard abused in the order named. 2. As for the motives of using antitussives, 30.1% of students answered because of curiosity, then 28.8%, in order to get a calm condition, and then 16.4%, to get along with friends. 3. As the result from seeing how much each drug abuser is contact with his family, frends, school, social surroundings and himself, every abuser appeared having higher degree of discontentment with family, school, society and himself excepting friends. 4. And when analyzed the relationship between their misconducting and drug-abusing, a close relationship was shown : mere abusers among misconduct-experienced students, and more misconduct-experienced students among abusers.

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The Effects after Implementing a Drug Utilization Review System on Contraindicated Drug use: A Systematic Review (사용금기 약물에 대한 의약품안전사용서비스의 효과에 대한 체계적 문헌고찰)

  • Lee, Heeyoung;Choi, Hyea Suk;Ji, Eunhee
    • Korean Journal of Clinical Pharmacy
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    • v.29 no.1
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    • pp.9-17
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    • 2019
  • Objective: The objective of the present study was to evaluate the effects of implementing a systematic Drug Utilization Review (DUR) system on contraindicated drug use and pharmaceutical expenditures in Korea. Methods: A literature search was conducted using search engines such as PubMed, EMBASE, NDSL, and RISS for relevant systematic studies. The database search was performed and updated in April 2018. Two independent reviewers evaluated the abstracts to find potentially eligible articles. Results: In total, 1433 potentially eligible studies were selected, and 11 articles were eventually shortlisted for inclusion in the present review system. The outcome showed that contraindicated drug use decreased after implementation of the DUR system in Korea. The analysis also showed that the DUR system contributed to a reduction in pharmaceutical expenditures. Conclusions: Our study showed that implementing the DUR system reduced both contraindicated drug use and pharmaceutical expenditures in Korea.

Reduced Addamycin Cytotoxicity in RIF-1 Multicell Spheroid Due to an Acidic Microenvironment

  • Um, Kyung-Il;Cheston, Sally B.;Suntharalingam, Mohan;Rhee, Juong-G.
    • Environmental Mutagens and Carcinogens
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    • v.17 no.1
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    • pp.7-11
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    • 1997
  • Variations in adriamycin uptake and cytotoxicity were studied in tumor cells that were grown in different growth states and microenvironments. RIF-1 tumor cells were maintained in an RPMI 1640 medium, and grown in either a monolayer or multicell spheroids. For exponentially growing cells, adriamycin cytotoxicity increased with increased dosage up to 2.5 $\mu$g/ml, and this cytotoxicity was reduced when the cells were grown in a plateau phase or in an acidic microenvironment (pH 6.6). This reduced cytotoxicity was correlated with the uptake of the drug. For multicell spheroids, the cytotoxicity of the drug was reduced dramatically, and this reduction was also correlated with a reduced uptake of the drug and an acidic pH inside of the spheroids. When the drug cytotoxicity was evaluated at different locations within the spheroids, the cells in the inner regions were least affected by the drug, suggesting that both an acidic microenvironment and noncycling plateau phase cells are contributing factors in decreasing the efficacy of the drug in an organized tissue, such as multicell spheroids.

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