This study was done to investigate effects of ${\gamma}$-irradiated pork feeding on the formation of glutathione S-transferase placental form positive (GST-P$^{+}$) foci, lipid peroxidation, cytochrome P450 system and microsomal glucose 6-phosphatase activity in diethylnitrosamine (DEN)-initiated rat hepatocarcinogenesis. Weaning Sprague-Dawley male rats were fed the diet containing ${\gamma}$-irradiated ground pork at the dose of 0, 3, 10, 30 kGy as a 20% of protein source for 8 weeks. One week after feeding, rats were intraperitoneally injected twice with a dose of DEN (50 mg/kg BW). As a promote.,0.05%phenobarbital was fed in drinking water from one week after DEN treatment until the end of experiment. At the end of 8th week, rats were sacrificed and hepatic GST-P$^{+}$ foci, microsomal malondialdehyde (MDA) and conjugated diene contents were determined. In addition, cytochrome P450 content and the activities of NADPH cytochrome P450 reductase and glucose 6-phosphatase were also measured. There was no significant effect by gamma irradiation on microsomal MDA content, conjugated diene, cytochrome P450 content and activities of NADPH cytochrome P450 reductase and glucose 6-phosphatase. However with DEN treatment, microsomal MDA content showed a increasing tendency. Cytochrome P450 content was also significantly increased while microsomal glucose 6-phophatase activity was significantly decreased with DEN treatment. However the activity of NADPH cytochrome P450 reductase was not affected. An interesting finding in this study was that the number and area of hepatic GST-P$^{+}$ foci of rats fed gamma irradiated pork were tended to be decreased by high dose of irradiation, but were not significantly different. These results might imply that the consumption of low dose of gamma irradiated pork does not affect the formation of hepatic GST-P$^{+}$ foci and lipid peroxide and membrane stability.ability.
Journal of the Korean Society of Food Science and Nutrition
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v.28
no.3
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pp.638-645
/
1999
This study was done to investigate effects of ${\gamma}$ irradiated beef feeding on the formation of gluta thione S transferase placental form positive(GST P+) foci, lipid peroxidation, cytochrome P450 system and microsomal glucose 6 phosphate activity in diethylnitrosamine(DEN) initiated rat hepatocarci nogenesis. Weaning Sprague Dawley male rats were fed the diet containing ${\gamma}$ irradiatied ground beef at the dose of 0, 3, 5kGy as a 20% of protein source for 8 weeks. One week after feeding, rats were intraperitoneally injected twice with a dose of DEN(50mg/kg BW). As a promoter, 0.05% phenobarbital was fed in drinking water from one week after DEN treatment until the end of experiment. At the end of 8th week, rats were sacrificed and hepatic GST P+ foci, microsomal malondialdehyde(MDA) and conjugated diene contents were determined. In addition, cytochrome P450 content and the activities of NADPH cytochrome P450 reductase and glucose 6 phosphatase were also measured. There was no significant effect by gamma irradiation on microsomal MDA content, conjugated diene, cytochrome P450 content and activities of NADPH cytochrome P450 reductase and glucose 6 phosphatase. However with DEN treatment, microsomal MDA content and conjugated diene contents were significantly changed. Cytochrome P450 content was also significantly increased while microsomal glucose 6 phophatase activity was significantly decreased with DEN treatment. However activity of NADPH cytochrome P450 reductase was not affected. An interesting finding in this study was that the number and area of hepatic GST P+ foci of the rats fed gamma irradiated beef were significantly(p<0.05) lower than those of the control. Such a lowering effect on GST P+ foci formation was highest at the dose of 3kGy than others. Overall results suggest that the consumption of low dose of gamma irradiated beef does not affect the formation of lipid peroxide, cytochrome P450 system and membrane stability.
Because of its stable quantity and quality, groundwater has long been a reliable source of drinking water for domestic users. Rapid economic growth and rising standards of living have in recent years put severe demands on drinking water supplies in Korea. Groundwaters that are currently being used for natural mineral water were hydrochemically evaluated and investigated in order to maintain their quality to satisfy strict health standards. There exist 15 natural mineral water plants in the Okcheon metamorphic belt. Characteristics of groundwaters are different from those of other areas in that electrical conductivity, hardness, contents of Ca, Mg and $HCO_3$are relatively high. The content of major cations is in the order of Ca>Mg, Na>K, whereas that of major anions shows the order of $HCO_3$>$SO_4$>Cl>F. The fact that the Ca-Mg-HCO$_3$type is mostly predominant among water types reflects that dissolution of carbonates that are abundantly present in the metamorphic rocks plays an important part in groundwater chemistry. Representative correlation coefficients between chemical species show Mg-$HCO_3$(0.92), Ca-$HCO_3$(0.88), Ca-Mg(0.80), Ca-Cl(0.78), Mg-$SO_4$(0.78), Ca-$SO_4$(0.71), possibly due to the effect by dissolution of carbonates, gypsum or anhydrite. Determinative coefficients between some chemical species represent a good relationship, especially for EC-(K+Na+Ca), Ca-$HCO_3$, Ca-Mg, indiacting that they are similar in chemical behaviors. According to saturation index, most chemical species are undersaturated with respect to major minerals, except for some silica phases. Groundwater is slightly undersaturated with respect to calcite and dolomite, whereas it is still greatly undersaturated with respect to gypsum, anhydrite and fluorite, Based on the Phase equilibrium in the systems $NA_2$O-$Al_2$$O_3$-$SiO_2$-$H_2$O and $K_2$O-$Al_2$$O_3$-$SiO_2$-$H_2$O, it is clear that groundwater is in equilibrium with kaolinite, evolved from the stability area of gibbsite during water-rock interaction. It is expected that chemical evolution of groundwater continue to proceed with increasing pH by reaction of feldspars, with calcite much less reactive.
1. Introduction Community medicine with the concept of comprehensive medical care and an ideal medical care delivery system not only for an individual or family but for the whole community has emerged. In April 1970, the Presbyterian Medical Center started a hospital based community health service project in order to improve the health of the people in rural areas. Prior to commencing a comprehensive medical care system, a family survey was needed. The major objective of this survey was to obtain information concerning the people and their environment so as to be able to plan and implement a comprehensive medical care program in Soyang-Myun. 2. Survey Method An interview using a family record form was carried out for each household. This family record form was designed to get information about demography, family planning, environmental sanitation and vital statistics. Prior to beginning, the members of the survey team were trained in interviewing techniques for three days. The team consisted of a public health nurse, four nurse-aides, a sanitarian and four health extension workers who are working in our project, The survey was carried out during the period November 1971 to March 1972. 3. Project area 1) Population of Soyang-Myun was 11,668; male, 5,962 and female, 5,706. Sex ratio: 104.5. 2) Households : 1,858 3) Family size: The average household consisted of 6.3 persons. 4) Educational level of householder a. Illiterate 13% b. No schooling but able to read 10% c. Preschool children 19% d. Primary school 47% e. Middle school 7% f. High school 3% g. College or University 1% 5) Occupational distribution of householders a. Farmer 67% b. Laborer 13% c. Office worker 4% d. Merchant 4% e. Industrial worker 2% f. Unemployed 8% g. Miscellaneous 2% 6) Religious affiliation a. No religion 74% b. Buddhist 12% c. Protestant 10% d. Catholic 4% 4. Survey results Living Environment : a. Home ownership 95% b. Kinds of roofing Straw-thatched house 84% Tile-roofed house 10% Slate-roofed house 5% Other 1% c. Floor space Less than 6 pyong 10% 6-10 pyong 53% 11-15 pyong 24% 16-20 pyong 9% More than 20 pyong 4% d. Radio ownership 80% Environmental Sanitation : a. the source of drinking water public well 49% private well 30% drainage water 9% steam water 8% well pump 3% water distribution system 1% b. Distance between well and toilet more than 16meters 38% 6-10 meter 31% 11-15 meters 14% Less than 6 meters 17% c. The status of well management Bad 72% Fair 26% Good 2% d. General sanitary state of house Bad 37% Fair 51% Good 12% e. House drainage system had no house drainage. 77% Family Planning : a. 24% of the people have used contraceptives, but 12% ceased to use them. 76% have never used contraceptives. b. used methods 1oop 68% oral pill 16% vasectomy 4% condom 1% tubal ligation 1% two or more methods 10% Maternal Health : a. The number of conceptions of housewives under 50 years of age. 11 times 26% 6 times 11% 5 times 11% 4 times 9% b. The place of delivery own house 88% hospital 1% others 11% Treatment of general sickness : a. The place of treatment Soyang Health Center 31% Hospital (private or otherwise) 26% Pharmacy 14% Herb medicine 5% Private care 5% No treatment 12% Miscellaneous 7% b. Usual causes of diseases Unknown 46% Tuberculosis 29% Neuralgia 8% CVA 3% Bronchitis 3% Others 11%
The geochemical and nitrogen isotopic analyses for shallow groundwater of Ogcheon area were carried out to characterize the geochemical characteristics of the groundwater and to identify the source of nitrate. Groundwater shows a neutral pH to weakly alkalic condition with pH values ranging from 6.9 to 8.4. The average of EC, Eh and DO is $344.2\;{\mu}s/cm$, 195 mV, 4 mg/L, respectively. According to piper diagram, chemical composition of groundwater is dominantly characterized by Ca-$HCO_3$ type. On the other hand, groundwater type in the study area include Ca-Cl+$NO_3$ type that were highly influenced by agricultural activities. $NO_3$-N concentration of the collected samples(n=45) range from 12.4 to 34.2 mg/l. These data show that the $NO_3$-N concentration exceeds Korea Drinking Water Standard (10 mg/l). The $\delta^{15}N-NO_3$ values range from $2.7^{\circ}/_{\circ\circ}$ to $18.8^{\circ}/_{\circ\circ}$. The enrichments of heavy isotope in the groundwater indicate that major origin of nitrate pollution were associated with animal and human waste. Also the denitrification may have partly contributed as one of the sources of nitrogen.
Since 2000, environmental policies and regulations in Korea are rapidly changing to TMDL(Total Maximum Daily Load) and nonpoint source control. This is due to bad water quality in drinking water sources. Although many environmental facilities having high removal efficiency are constructed and applied in nationwide for controling various pollutants from wastewaters, the water quality in rivers is worse and worse because of nonpoint pollution. In fact, TMDL is a new environmental regulation controling total daily loadings from watershed areas. Actually, the nonpoint pollutant is originated from various landuses and its control is based on TMDL regulation. Therefore, this research is performed to determine the size of detention basin to control nonpoint pollutants from resort developing areas. The detention basin is one of best management practices, which is useful for controling pollutants and flooding from the developing areas. However, it should be designed and constructed with cost effective method. Recent 10 years rainfall data are used to determine the size of detention basin. The cost effective size is determined to 7.4mm accumulated rainfall.
Journal of Korean Society of Environmental Engineers
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v.28
no.1
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pp.74-80
/
2006
Benefit transfer is a method, which obtains an estimate for the economic valuation of non-marketed commodities at a given site through the analysis of studies that have been previously carried out to value similar commodities at a different location. The objective of this study was to estimate benefit transfer values for the construction of the integrated sewerage system in the catchment area of dams in Korea. For pooled data analysis, five models were suggested in this study. Among five models, model 2 showed only 6 to 7% errors when the willingness-to-pay(WTP) predicted in the policy-site, Dam Soyang was compared with that estimated using contingent valuation method(CVM) in the study-sites, Dams Namgang, Hapcheon, and Daecheong. However, the WTP estimate predicted by model 1 showed the absolute errors of 42 to 47% when it was compared with WTP estimated using CVM in Dams Andong and Imha. It seemed that residents of Dams Andong and Imha have feeling of being victimized since two dams were constructed very adjacently, the upstream area was designated as drinking water source protection zone, and thereafter their developmental economical actions have been significantly restricted.
VOCs were detected in the 21 groundwaters out of 37 groundwaters sampled from around the Hanam Industrial Complex and the Gwangju stream. Ten components of chlorinated aliphatic hydrocarbons of VOCs were detected in the 18 groundwater samples. Among them, total trihalomethanes (TTHM) concentration is in the range of $0.1~36.2{\;}\mu\textrm{g}/L$, CECs concentration is $2.3~190{\;}\mu\textrm{g}/L$, and chlorinated solvents concentration containing PCE, TCE, etc. is $0.1~124.2{\;}\mu\textrm{g}/L$ respectively. Ten components of the aromatic hydrocarbons of VOCs were detected in the 5 groundwater samples, but their concentration are less than $1{\;}\mu\textrm{g}/L$. Detection frequency and concentration of the chlorinated aliphatic hydrocarbons components from the groundwaters in the Hanam Industrial Complex are higher than those of nearby downtown Gwangju stream. VOCs components except for TCE are lower than the MCL of USGS drinking water standard. TCE concentration of the 2 groundwater samples is over MCL, whose concentrations are 5 and 25 times higher than MCL, respectively. TCE is detected from the H8 and H10 groundwater samples and CFCs is detected H8 and H11 groundwater samples in the Hanam Industrial Complex. TTHM in study area is estimated from leakage of the main waters or sewage waters. Because most of the studied groundwater is under an aerobic condition, aromatic hydrocarbons are well degraded. But chlorinated aliphatic hydrocarbons are degraded very slowly.
Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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v.28
no.2
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pp.273-280
/
2010
This study aims to research into a plan for the spatial design on the major facilities in new-town region in Mongolia by using the spatial analytical technique in GIS. In case of Mongolian region, the demand for new-town development is rapidly increasing around Ulaanbaatar, where is the capital. On the other hand, the adequately relevant ground or the spatial-design technique is failing to be applied. This study extracted the region available for developing new down by using spatial analytical technique in GIS, and researched into the spatial-design plan for housing complex, filtration plant, sewage disposal plant, power plant, general park, crematory. The housing complex in the targeted region could be known to be adequate to be positioned around watercourse and road. It could be known to be adequate for filtration plant, which is the source of drinking water, to be located in the upper-stream region of a river, which is secured good quality of water, and for sewage disposal plant to be located in the lower-stream region available for minimizing occurrence of contamination. It is judged to be required for a proposed site of power plant to be located in the upper-stream region, for the park unit, which is space of the living culture, to be repaired and expanded the existing facilities, and for traffic network to be expanded through predicting demand along with new-town development. It is judged to be probably needed to be reflected even the flexible aspect for changing design through surveying the feasibility and economic efficiency on the future spatial design.
Hydrochemical analyses, carbon isotopic (${\delta}^{13}C_{DIC}$) analyses, and noble gas isotopic ($^3He/^4He$ and $^4He/^{20}Ne$) analyses of the Dalki carbonate waters in the Chungsong area were carried out to elucidate their hydrochemical composition and to determine the source of $CO_2$ gas and noble gases. The carbonate waters have a pH of between 5.93 and 6.33, and an electrical conductivity 1950 to $3030{\mu}S/cm$. The chemical composition of all carbonate waters was Ca(Mg)-$HCO_3$, with a high Na content. The contents of Fe, Mn, and As in some carbonate waters exceed the limit stipulated for drinking water. The concentrations of major ions are slightly higher than those reported previously. The ${\delta}^{13}C_{DIC}$ values range from -6.70‰ to -4.47‰, indicating that the carbon originated from a deep-seated source. The $^3He/^4He$ and $^4He/^{20}Ne$ ratios vary from $7.67{\times}10^{-6}$ to $8.38{\times}10^{-6}$ and from 21.32 to 725.7, respectively. On the $^3He/^4He$ versus $^4He/^{20}Ne$ diagram, the noble gas isotope ratios plot in the field of a deep-seated source, such as mantle or magma. We therefore conclude that $CO_2$ gas and noble gas in the Dalki carbonate waters originated from a deep-seated source, rather than an inorganic $CO_2$ origin as suggested in a previous study.
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