• Journal of Dental Anesthesia and Pain Medicine
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• 제20권1호
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• pp.19-27
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• 2020

Background: Surgical extraction of third molars is associated with postoperative pain and swelling at the extraction site. Pain is commonly managed using non-steroidal anti-inflammatory drugs (NSAIDs). Postoperative pain is usually moderate to severe in the first 12 h postoperatively and lasts for 3-5 days. However, with NSAIDs, these symptoms usually subside within 24 h. Diclofenac sodium and etodolac are NSAIDs, more selectively cyclooxygenase-2 inhibitors, with good analgesic efficacies. Methods: We compared the safety and analgesic efficacy of diclofenac sodium with etodolac peroral after surgical extraction of third molars in a double-blind, double-dummy, parallel-group study. The subjective pain improvement and pain relief after 2, 6, 24, 48, and 72 h using the visual analogue scale were measured as the study outcome. Results: Etodolac was equivalent to diclofenac sodium in pain alleviation at all postoperative time periods. No significant differences were found between diclofenac sodium and etodolac groups (P > 0.05). Both study medications were well tolerated and safe with mild adverse effects in only a few participants. Conclusion: Diclofenac sodium and etodolac are comparable in terms of analgesic efficacy and safety after surgical removal of third molars.

• 한방안이비인후피부과학회지
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• 제13권2호
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• pp.200-210
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• 2000

objective to ascertain whether the concept of the therapeutic side is associated with changes in the blind sport mapping that represents the brain function. design Physiological blind spot maps were used as an integer of brain activity before and after acupuncture needling on the meridian point Hapkok(合谷) and Techung(太衝) in the unilateral side decided by double-blind controlled study(20 subjects). setting outpatient clinic participants: adult volunteers intervention twenty subjects were divided into two comparative groups and underwent specific acupuncture therapy on the unilateral side. Blinded examiners obtained reproducible pre and post-acupuncture cortical maps, which were subjected to statistical analysis. main outcome measures Brain activity was demonstrated by reproducible circumferential measurements of cortical hemispheric blind spot maps before and after acupuncture on the unilateral side. in case of acupuncture needling on the ipsilateral side of an enlarged side of bilnd spot, there were reduction of blind spot in 7 cases of 10 subjects, and enlargement in 3 cases. in case of acupuncture needling on the contralateral side of the enlarged side of blind spot, there were enlargement of blind spot in 6 cases of 10 subjects, and reduction in 4 cases. results the significant changes in the blind spots before and after acupuncture were observed Acupuncture needlings on the ipsilateral or contralateral side of an enlarged cortical map were associated with the concept of the therapeutic side traditionally accepted in the oriental medical society. Acupuncture needling on the ipsilateral side of an enlarged blind spot map is associated with the reduction of map, and increaed contralateral cortical activity. Acupuncture needling on the side opposite an enlarged blind spot map is associated with the enlargement of map, and decreased cortical activity. conclusion Reproducible maps of cortical responses can be used to measure the neurological consequences of acupuncture needling. Acupuncture can affect the somatic sensory informations that reach to the contralateral thalamus, and so affect thalamic integration. we found that acupuncture therapy may be associated with an increase or a decrease in brain function depending on the side of acupuncture needling. thus, the traditional concept of the contralateral therapeutic theory in acupuncture approach has the clinical significance in the view of brain function.

• Journal of Acupuncture Research
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• 제20권1호
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• pp.22-34
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• 2003

Objective : To ascertain whether the concept of the treatment side is associated with changes in the blind spot mapping that represents the brain function. Methods : Among the outpatients who visited to Department of Acupuncture & Moxibustion, National Medical Center from March 2002 to October 2002, we selected 40 clinical trial volunteers that showed right side physiological blind spot more enlarged than left, and underwent the examinations of Department of Opthalmology, National Medical Center for ruling out the pathological conditions. Physiological blind spot maps were used as an integer of brain activity before and after electroacupuncture application on the unilateral ST36 meridian point by dividing 40 subjects into two comparative groups for double-blind controlled study. Results: The significant changes in the blind spots were observed. Electroacupuncture application on the ipsilateral or contralateral ST36 of an enlargement cortical map were associated with the concept of determining the treatment side. In the case of electroacupuncture application on the ipsilateral side of an enlarged blind spot, there were decrease of $4.11{\pm}8.56cm$(17.3%) in blind spot perimetry length(p < 0.05). In the case of contralateral side, there were increase of $3.19{\pm}5.40cm$(13.7%) in blind spot perimetry length(p<0.05). The Differences were statistically significant(p<0.05). Conclusions: We found that eletroacupuncture application was associated with an increase or decrease in the brain function in the view of blind spot changes depending on the treatment side. These results suggest that the traditional acupuncture therapeutic strategy with determining the treatment side has clinical significance in the view of the brain function.

• KSII Transactions on Internet and Information Systems (TIIS)
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• 제16권4호
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• pp.1266-1285
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• 2022

Compact E-cash is the first scheme which can withdraw 2^l coins within 𝒪(1) operations and then store them in 𝒪(𝑙) bits. Because of its high efficiency, a lot of research has been carried out on its basis, but no previous research pay attention to the privacy of payees and in some cases, payees have the same privacy requirement as payers. We propose a double-blind compact E-cash scheme, which means that both the payer and the payee can keep anonymous while spending. In our scheme, the payer and the bank cannot determine whether the payees of two different transactions are the same one and connect the payee with transactions related to him, in this way, the privacy of the payee is protected. And our protocols disconnect the received coin from previous transaction, then, the coin can be transferred into an unspent coin which belongs to the payee. The proposed e-cash scheme is secure within y-DDHI and LRSW assumption.

• 전기학회논문지
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• 제57권7호
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• pp.1290-1294
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• 2008

We present a novel deblurring algorithm for bi-level images blurred by some parameterizable point spread function. The proposed method iteratively searches unknown parameters in the point spread function and noise-to-signal ratio by minimizing an objective function that is based on the binariness and the difference between two intensity values of restoring image. In simulations and experiments, the proposed method showed improved performance compared with the Wiener filtering based method in terms of bit error rate after segmentation.

• 한국영양학회:학술대회논문집
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• 한국영양학회 2004년도 춘계학술대회
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• pp.132-132
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• 2004

• 한국식품영양과학회:학술대회논문집
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• 한국식품영양과학회 2003년도 정기총회 및 54차 학술발표회:건강기능식품의 유효성평가
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• pp.94-94
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• 2003

• 한국생활과학회지
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• 제13권3호
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• pp.467-475
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• 2004

The purpose of this study was to examine the sewing construction of a double robe, the difference between the single and double robe, and the size and construction method of the double robe through a close analysis of a replica to facilitate a better understanding of the robe making in late Chosun dynasty. The results were as follows: 1. There was no significant difference in the design and sewing method between the girl's robe and an adult's even though the girl's robe was much smaller. 2. The girl's robe differed from its modern counterparts in some respects: unlike modem robes, Chungyun's robe consisted of two-layers in which the four layers were sewn together and it could be seen most clearly in the way the collar was stitched only onto the outer layer. The two layers seemed to be put on successively since they were not sewn together. The inner collars of the two robes were sewn together when the maker put on a coat string to the outer robe, and the two robes were put together with hemming and blind stitch at the top of the outer collars to make the robe formally stable, which clearly distinguished the princess' robe from a single, for example, four-layered robe. The robe was constructed using traditional sewing methods including broad stitch, back stitch, hemming, and blind stitch, and each stitch was only about 1 mm wide. 3. The maker of the robe managed to construct a formally stable and aesthetically satisfactory robe with the least amount of fabric and proper sewing methods.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제42권2호
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• pp.84-89
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• 2016

Objectives: To compare the efficacy of intravenous ondansetron (4 mg, 2 mL) and granisetron (2 mg, 2 mL) for preventing postoperative nausea and vomiting (PONV) in patients during oral and maxillofacial surgical procedures under general anesthesia. Materials and Methods: A prospective, randomized, and double blind clinical study was carried out with 60 patients undergoing oral and maxillofacial surgical procedures under general anesthesia. Patients were divided into two groups of 30 individuals each. Approximately two minutes before induction of general anesthesia, each patient received either 4 mg (2 mL) ondansetron or 2 mg (2 mL) granisetron intravenously in a double blind manner. Balanced anesthetic technique was used for all patients. Patients were assessed for episodes of nausea, retching, vomiting, and the need for rescue antiemetic at intervals of 0-2, 3, 6, 12, and 24 hours after surgery. Incidence of complete response and adverse effects were assessed at 24 hours postoperatively. Data was tabulated and subjected to statistical analysis using the chi-square test, unpaired t-test, or the Mann-Whitney U-test as appropriate. A P-value less than 0.05 was considered statistically significant. Results: There was no statistically significant difference between the two groups for incidence of PONV or the need for rescue antiemetic. Both study drugs were well tolerated with minimum adverse effects; the most common adverse effect was headache. The overall incidence of complete response in the granisetron group (86.7%) was significantly higher than the ondansetron group (60.0%). Conclusion: Granisetron at an intravenous dose of 2 mg was found to be safe, well tolerated, and more effective by increasing the incidence of complete response compared to 4 mg intravenous ondansetron when used for antiemetic prophylaxis in maxillofacial surgery patients receiving general anesthesia. Benefits of granisetron include high receptor specificity and high potency, which make it a valuable alternative to ondansetron.

• The Korean Journal of Pain
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• 제32권2호
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• pp.97-104
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• 2019

Background: This study was conducted to compare the effectiveness of low-dose ketamine versus ketorolac in pain control in patients with acute renal colic presenting to the emergency department (ED). Methods: This is a double-blind randomized clinical trial. The initial pain severity was assessed using the numerical rating scale (NRS). Then, ketamine or ketorolac was administered intravenously at a dose of 0.6 mg/kg and 30 mg respectively. The pain severity and adverse drug reactions were recorded 5, 15, 30, 60, and 120 min thereafter. Results: The data of 62 subjects in the ketamine group and 64 patients in the ketorolac group were analyzed. The mean age of the patients was $34.2{\pm}9.9$ and $37.9{\pm}10.6\;years$ in the ketamine and ketorolac group, respectively. There was no significant difference in the mean NRS scores at each time point, except for the 5 min, between the two groups. Despite a marked decrease in pain severity in the ketamine group from drug administration at the 5 min, a slight increase in pain was observed from the 5 min to the 15 min. The rate of adverse drug reactions, including dizziness (P = 0.001), agitation (P = 0.002), increased systolic blood pressure (> 140 mmHg), and diastolic blood pressure (> 90 mmHg) was higher in the ketamine group. Conclusions: Low dose ketamine is as effective as ketorolac in pain management in patients with renal colic presenting to the ED. However, it is associated with a higher rate of adverse drug reactions.