• Journal of Oriental Neuropsychiatry
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• v.20 no.2
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• pp.163-176
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• 2009

Objectives : To address most probable and suitable method for designing clinical trial intervening Traditional Korean Herbal Medicine on hwa-byung. Study Design : A systematic review of research studies of complementary and/or alternative medical(CAM) treatment of depression, and of domestic clinical trials of Traditional Korean Medicine, and of Chinese clinical trials of Traditional Chinese Medicine. Methods : Randomized, controlled trials(RCTs) of treatment of depression intervening herbal medicine were searched through MEDLINE, Cochrane Library, and CNKI databases. Also, domestic RCTs intervening Traditional Korean Herbal Medicine were searched through Korean Traditional Knowledge Portal and Korean studies Information Service System(KISS). Studies were evaluated using Iadad scale and self-designed tool for this study. Results : Thirty four RCT studies( 10 from MEDLINE, 16 from CNKI, 8 domestic studies) of herbal medicine met inclusion criteria. Mean Jadad score of studies published in English was 2.8${\pm}$0.79, in Chinese 1.94${\pm}$0.77, and in Korean 2.75${\pm}$0.71. Twenty one percent of studies included pattern differentiation in their inclusion criteria. Twenty nine percent of studies used combined treatment of herbal and conventional medicine. Among studies on depression, 9% included Complementary Medical assessing tools. Conclusions : There is shortage of domestic clinical trial involving herbal medicine. In China, studies tend to focus on investigating effect of Combined treatment of herbal and conventional medicine on depression. Clinical trial(s) of hwa-byung should provide good internal validity by describing methodology for randomization, double-blinding, and attrition. Also, specific guideline for clinical trial, including Traditional Korean Medical aspects across inclusion criteria, and assessing tools is needed.

• The Journal of Korean Academy of Prosthodontics
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• v.55 no.1
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• pp.18-25
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• 2017

Purpose: The aim of this study was to evaluate the effect of two types of coloring agents and the number of application on the color of zirconia. Materials and methods: Monolithic zirconia specimens ($15.7mm{\times}15.7mm{\times}2.0mm$) (n = 33) was prepared and divided into 11 groups. Each experimental group was coded as a1-a5, w1-w5 according to the type of coloring agent and number of application. Specimens with no coloring agent applied were set as control group. The color difference of specimen was measured by using double-beam spectrophotometer, and calculated color difference (${{\Delta}E^*}_{ab}$), translucency parameter (TP). All data was analyzed with two-way ANOVA, multiple comparison $Sch{\acute{e}}ffe$ test, Pearson correlation and linear regression analysis. Results: As the number of application increased, values of $CIE\;L^*$ was decreased, but values of $CIE\;b^*$ was increased in both coloring agents. However, there was no significant difference on values of translucency parameter. The color difference range of each group was ${0.87{\Delta}E^*}_{ab}$ to ${9.43{\Delta}E^*}_{ab}$. Conclusion: In this study, type of coloring agent and the number of application did not affect the color difference of zirconia.

• The Journal of Korean Academy of Prosthodontics
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• v.60 no.4
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• pp.431-441
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• 2022

The digital facebow device records the trajectory of the mandibular movement where it is then reflected on the computer-aided design software, leading to an improvement on treatment outcomes of prosthetic restorations. In this clinical case, using a digital technology, an implant placement and prosthetic restoration were done in a patient who has lost maxillary and mandibular molars. Following an intraoral scan, a surgical stent for implant surgery was fabricated based on digital diagnostic wax-up, and implants were installed. After six months of sufficient osseointegration, customized abutments and the first temporary prostheses were delivered. Then two months later, at an abutment level, an intraoral scan and digital facebow transfer device were used to mount the intraoral scan data on a virtual articulator, and record the mandibular movements. Once the second temporary prostheses were fabricated and delivered on a basis of the mandibular movement, the definitive zirconia prostheses were designed and delivered based on a stabilized occlusion that was duplicated via double scan technique.