• Title/Summary/Keyword: Double Number Line

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Over-Expression of Ephrin-A5 in Mice Results in Decreasing the Size of Progenitor Pool through Inducing Apoptosis

  • Noh, Hyuna;Park, Soochul
    • Molecules and Cells
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    • v.39 no.2
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    • pp.136-140
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    • 2016
  • Eph receptors and their ligands, ephrins, mediate cell-to-cell contacts in a specific brain region and their bidirectional signaling is implicated in the regulation of apoptosis during early brain development. In this report, we used the alpha(${\alpha}$)-Cre transgenic line to induce ephrin-A5 over-expression in the distal region of the neural retina. Using this double transgenic embryo, we show that the over-expression of ephrin-A5 was responsible for inducing massive apoptosis in both the nasal and temporal retinas. In addition, the number of differentiated retinal neurons with the exception of the bipolar neuron was significantly reduced, whereas the laminar organization of the mature retina remained intact. Consistent with this finding, an analysis of the mature retina revealed that the size of the whole retina-particularly the nasal and temporal regions-is markedly reduced. These results strongly suggest that the level of ephrin-A5 expression plays a role in the regulation of the size of the retinal progenitor pool in the neural retina.

Static and dynamic responses of a tied-arch railway bridge under train load

  • Gou, Hongye;Yang, Biao;Guo, Wei;Bao, Yi
    • Structural Engineering and Mechanics
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    • v.71 no.1
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    • pp.13-22
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    • 2019
  • In this paper, the static and dynamic responses of a tied-arch railway bridge under train load were studied through field tests. The deflection and stresses of the bridge were measured in different static loading scenarios. The dynamic load test of the bridge was carried out under the excitation of running train at different speeds. The dynamic properties of the bridge were investigated in terms of the free vibration characteristics, dynamic coefficients, accelerations, displacements and derailment coefficients. The results indicate that the tie of the measuring point has a significant effect on the vertical movement of the test section. The dynamic responses of arch bridge are insensitive to the number of trains. The derailment coefficients of locomotive and carriage increase with the train speed and symmetrically distributed double-line loads reduce the train derailment probability.

Analysis of Fatty Acid in Rice Bran Oil by Gas Chromatography (Gas Chromatography에 의(依)한 미강유(米糠油)의 지방산분석(脂肪酸分析))

  • Chung, T.M.;Shin, J.S.
    • Applied Biological Chemistry
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    • v.9
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    • pp.29-33
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    • 1968
  • Through an experiment with gas chromatography carried out using diethylene glycol succinate(DEGS) as the packing material of the column, we have obtained the correction factor between the weight ratio and the peak dimension of the saturated fatty acid methyl esters of C10, C12, C14, C16, and C18 and unsaturated fatty acid methyl esters of oleic acid, linoloic acid, and linolenic acid, employing the detector of thermal conductivity type. Quantitative analysis of the fatty acids contained in rice Bran oil was performed with the above correction factor and the results are as follows; 1. Main components were found to be palmitic acid, oleic acid sand linolenic acid. No trases of capric acid (C10) lauric acid (C10) were found. 2. It was confirmed that there were straight line relation between the logarism retention time of each fatty acid and the number of carbon of saturated fatty acid or the number of double bond of other fatty acids having the same number of carbon. 3. The correction factor became larger as to the number of carbon increased up to C18 in case of saturated fatty acids, end as for other fatty acids, and as for other fatty acids of the same carbon number, it became larger according as the number of double bond increased.

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HI superprofiles of galaxies from THINGS and LITTLE THINGS

  • Kim, Minsu;Oh, Se-Heon
    • The Bulletin of The Korean Astronomical Society
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    • v.46 no.2
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    • pp.68.3-69
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    • 2021
  • We present a novel profile stacking technique based on optimal profile decomposition of a 3D spectral line data cube, and its performance test using the HI data cubes of sample galaxies from HI galaxy surveys, THINGS and LITTLE THINGS. Compared to the previous approach which aligns all the spectra of a cube using their central velocities derived from either moment analysis, single Gaussian or hermite h3 polynomial fitting, the new method makes a profile decomposition of the profiles from which an optimal number of single Gaussian components is derived for each profile. The so-called superprofile which is derived by co-adding all the aligned profiles from which the other Gaussian models are subtracted is found to have weaker wings compared to the ones constructed in a typical manner. This could be due to the reduced number of asymmetric profiles in the new method. A practical test made on the HI data cubes of the THINGS and LITTLE THINGS galaxies shows that our new method can extract more mass of kinematically cold HI components in the galaxies than the previous results. Additionally, we fit a double Gaussian model to the superprofiles whose S/N is boosted, and quantify not only their profile shapes but derive the ratio of the Gaussian model parameters, such as the intensity ratio and velocity dispersion ratio of the narrower and broader Gaussian components. We discuss how the superprofile properties of the sample galaxies are correlated with their other physical properties, including star formation rate, stellar mass, metallicity, and gas mass.

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Development of the pyramiding lines with strong culm genes derived from crosses among the SCM near isogenic lines in rice

  • Ookawa, Taiichiro;Kamahora, Eri;Ebitani, Takeshi;Yamaguchi, Takuya;Murata, Kazumasa;Iyama, Yukihide;Ozaki, Hidenobu;Adachi, Shunsuke;Hirasawa, Tadashi;Kanekatsu, Motoki
    • Proceedings of the Korean Society of Crop Science Conference
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    • 2017.06a
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    • pp.21-21
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    • 2017
  • Severe lodging has recurrently occurred at strong typhoon's hitting in recent climate change. The identification of quantitative trait loci (QTLs) and their responsible genes associated with a strong culm and their pyramiding are important for developing high-yielding varieties with a superior lodging resistance. To identify QTLs for lodging resistance, the tropical japonica line, Chugoku 117 and the improved indica variety, Habataki were selected as the donor parent, as these had thick and strong culms compared with the temperate japonica varieties in Japan such as Koshihikari. By using chromosome segment substitution lines (CSSLs) in which chromosome segments from the japonica variety were replaced to them from Habataki, we identified the QTLs for strong culm on chrs. 1 and 6, which were designated as STRONG CULM1 (SCM1) and STRONG CULM2 (SCM2), respectively. By using recombinant inbred lines (BILs) derived from a cross between Chugoku 117 and Koshihikari and introgression lines, we also identified the other QTLs for strong culm on chrs. 3 and 2, which were designated as STRONG CULM3 (SCM3) and STRONG CULM4 (SCM4), respectively. Candidate region of SCM1 includes Gn1 related to grain number. SCM2 was identical to APO1, a gene related to the control of panicle branch number, and SCM3 was identical to FC1, a strigolactone signaling associated gene, by performing fine mapping and positional cloning of these genes. To evaluate the effects of SCM1~SCM4 on lodging resistance, the Koshihiakri near isogenic line (NIL) with the introgressed SCM1 or SCM2 locus of Habataki (NIL-SCM1, NIL-SCM2) and the another Koshihikari NIL with the introgeressed SCM3 or SCM4 locus of Chugoku 117 (NIL-SCM3, NIL-SCM4) were developed. Then, we developed the pyramiding lines with double or triple combinations derived from step-by-step crosses among NIL-SCM1 NIL-SCM4. Triple pyramiding lines (NIL-SCM1+2+3, ~ NIL-SCM1+3+4) showed the largest culm diameter and the highest culm strength among the combinations and increased spikelet number due to the pleiotropic effects of these genes. Pyramiding of strong culm genes resulted in much increased culm thickness, culm strength and spikelet number due to their additive effect. SCM1 mainly contributed to enhance their pyramiding effect. These results in this study suggest the importance of identifying the combinations of superior alleles of strong culm genes among natural variation and pyramiding these genes for improving high-yielding varieties with a superior lodging resistance.

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Development of a Mobile Tower-yarder with Tractor (I) - Design and Manufacture - (트랙터부착형 타워집재기 개발(I) - 설계 및 제작-)

  • Park, Sang-Jun;Kim, Bo-Kyun
    • Journal of Korean Society of Forest Science
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    • v.97 no.1
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    • pp.61-70
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    • 2008
  • This study was conducted to develop a mobile tower-yarder with tractor for agriculture and forestry that is the efficient yarder in steep terrains, thinning operation and small scale logging operation. It was designed and manufactured that the power source of tower-yarder is equiped three hydraulic pump connected to PTO of tractor, and three hydraulic pump is used to operate the four motor for drum, the cylinder for clutch of interlocker, the cylinder for tower expanding and the out-rigger cylinder. It was to adopt the running skyline system and the inter-lock function, and to equip the double capstan drum, the storage drum and the clutch for interlock in the development of tower-yarder. It was to develop the tower-yarder which the winch torque of double-capstan drum, the traction force of double-capstan drum, the number of rotation of double-capstan drum and the line speed is $191kg{\cdot}m$, 1,910 kgf, 220.5 rpm and 138.5 m/min, respectively. And it was known that the optimum flange diameter of the main and haulback storage drum is about 360 mm and about 460 mm in order to storage the main line length of 250m and the haulback line length of 450 m. The carriage was made to adopt the running skyline system and to equip the lock function in order to the convenience of chocking and the fall down preventing of tree. It was provided to develop the wire remote controller for the inter-lock function, the convenience of control and the efficiency of yarding. In development process, this tower-yarder was attached the 3-point linkage hitch equipment and the tire wheel for the traction and moving of tower-yarder. Also, it was equipped that the out-rigger and the guy line in order to raise the safety and efficiency of yarding of tower-yarder.

A Study on the Fare Elasticities of DST Applications; An Empirical Analysis (경전선 이단적재열차(DST) 도입을 위한 운임 탄력성 조사 연구)

  • Yun, Donghee;Lee, Jinsun;Kim, Ickhee
    • Journal of the Korean Society for Railway
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    • v.15 no.5
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    • pp.517-523
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    • 2012
  • Double Stack Train(DST) is being used variously around USA and Canada. The greatest advantage of the DST is mass transportation without extending the length of freight train and number of cars. So the DST system can be a kind of innovative train to increase the competitiveness of rail logistic business. As the domestic rail logistic increase, for enhancement of environment friendly green transportation amount, the DST needs more for efficiency. In this study, as the alternative way to introduce the DST to the Kyungbu Line, it's investigated the extensibility of rail freight with the relation of rail fare discount and examined the necessity of pilot business to the Kyungjeon Line which was expected comparatively lower cost. If the DST system is introduced to the Kyungjeon Line, the cost of mass transportation can be much lower and then the comparativeness of rail transportation will be increased, therefore logistic companies can have some margin additionally. In the result of survey to the related companies, if rail transportation fare is 37.7 % cheaper than current road transportation fare, the modal shift can be transferred by maximum 100%.

Design Optimization of Composite Radar Absorbing Structures to Improve Stealth Performance

  • Jang, Byungwook;Kim, Myungjun;Park, Jungsun;Lee, Sooyong
    • International Journal of Aeronautical and Space Sciences
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    • v.17 no.1
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    • pp.20-28
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    • 2016
  • In this study, an efficient method of designing laminate composite radar absorbing structures (RAS) is proposed with consideration given to the structural shape so as to improve aircraft stealth performance. The calculation of the radar cross section (RCS) should be decreased to enhance the efficiency of the stochastic optimization when designing an RAS. In the proposed method, RAS are optimized to match up the input impedance of the minimal RCS, which is obtained by using physical optics and the transmission line theory. Single and double layer dielectric RAS for aircraft wings are employed as numerical examples and designed using the proposed method, RCS minimization and reflection coefficient minimization. The availability of the proposed method is assessed by comparing the similarity of the results and computation time with other design methods. According to the results, the proposed method produces the same results as the stochastic optimization, which adopts the RCS as the objective function, and can improve RAS design efficiency by reducing the number of RCS analyses.

A Study on the Control of Multi-Input Hydraulic System for Robot Leg using LQR Technique (LQR 기법을 이용한 로봇다리의 다중입력 유압시스템 제어에 관한 연구)

  • Yoo, Sam-Hyeon;Lim, Soo-Chul
    • Journal of the Korea Institute of Military Science and Technology
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    • v.12 no.4
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    • pp.540-547
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    • 2009
  • In the near future, military robots are likely to be substituted for military personnel in the field of battle. The power system of a legged robot is considerably more complex than the one used for a land vehicle because of the coordination and stability issues due to the large number of degree of freedom. In this paper, a servovalve-piston combination system for a straight-line motion of robot leg is modeled as three degree of freedom based on double inputs and single output transfer function. The output is the displacement of piston from neutral. The inputs are valve displacement from neutral and arbitrary load force in this system. LQR(Linear Quadratic Regulator) technique is applied in order to achieve robust stability and fast responses of the system. The Kalman filter loop, rejection of disturbance and noise, riccati equation, filter gain matrix, and frequency domain equality are analyzed and designed.

A Study on the Comprehensive Approach to Health Education: Cooperative Learning (협동학습(Cooperative Learning)을 적용한 보건교육 수업에 관한 연구)

  • 김은주
    • Korean Journal of Health Education and Promotion
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    • v.21 no.3
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    • pp.151-177
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    • 2004
  • Recently, the educational community has attempted to implement the theory of multiple intelligences. In approaching multiple intelligences, teachers have applied the same structural approach which has been so successful with cooperative learning. Cooperative learning is easy to learn and implement, fun for teachers and students, and produce profoundly positive outcomes along a remarkable number of dimensions. Different structures are designed for different outcomes, including enhanced mastery of subject matter, improved thinking skills, team building, class building, development of social character and social skills, communication skills, classroom management, classroom discipline, and development of and engagement of each of the multiple intelligences. Cooperative learning is becoming an increasingly popular teaching strategy. In this study, it is aimed to clarify the application of cooperative learning in health education. Cooperative Learning in health education enhances student learning by: 1) providing a shared cognitive set of information between students, 2) motivating students to learn the material, 3) ensuring that students construct their own health knowledge, 4) providing formative feedback, 5) developing social and health group skills necessary for success outside the classroom, and 6) promoting positive interaction between members of different cultural and socio-economic groups. Cooperative Learning structures and techniques in health education are following. Flash Card, Focused Listing, Structured Problem-solving, Paired Annotations, Structured Learning Team Group Roles, Send-A-Problem, Value Line, Uncommon Commonalities, Team Expectations, Double Entry Journal, Guided Reciprocal Peer Questioning, What if. Because the purpose of health education is the practice, therefore health specialists have to guide powerful and effective teaching method The application of cooperative learning in health education may improve its effectiveness.