• Radiation Oncology Journal
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• 제14권4호
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• pp.323-332
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• 1996

목적 : 방사선 치료에 있어서 조직내 등선량 분포곡선을 변형시킬 목적으로 쐐기 차폐물이 사용되고 있는데 최근 기존의 고정 쐐기와는 다르게 비대칭적인 콜리메이터인 Independent Jaw에 의해 등선량 분포곡선을 변형시키는 동적 쐐기 기법이 실용화 되고 있으나 아직 그 방사선 물리학적인 특성에 대해서는 잘 알려져 있지 않다. 이에 본 저자는 기존의 고정 쐐기와 비교하여 조직내 방사선량 분포의 특성을 알아보고자 본 연구를 계획하였다. 대상 및 방법 : 물 판톰, 폴리 스타이린 판톰, 평균 유방 모형 판톰을 대상으로 전리함, 필름, TLD 등을 이용하여 동적 쐐기와 고정 쐐기의 선량 분포를 측정하여 비교하였다. 방사선원은 선형 가속기의 6MV x선을 사용하였고 $15{\times}15$ 조사면에서 15, 30, 45도 쐐기를 이용하였다 조직내선량 분포는 전리함과 필름 선량계를 사용하였고, 유방 접선 치료방식에서의 반대편 유방 조사선량은 TLD를 사용하였다. 결과 : 1) 조직내 $\%$심도 선량은 고정 쐐기의 경우 심도 선량 깊이가 깊어지는 방사선의 경화 현상이 뚜렷하였으나 동적 쐐기의 경우에는 발견할 수 없었으며 그 $\%$심도선량은 개방 조사면과 유사하였다. 2) 조직내 등선량 분포 곡선을 보면 동적 쐐기의 경우 고정 쐐기와는 달리 원하는 깊이, 원하는 조사면에서 원하는 쐐기 각도를 얻을 수 있었으며 쐐기 각도를 이루는 등선량 분포 곡선이 고정 쐐기에 비해 더욱 직선적이었다. 3) 산란선량은 동적 쐐기의 경우 개방 조사면과 그 양이 거의 동일하였으며 유방보존술에서의 접선 조사방식의 방사선치료에서 고정 쐐기 대신에 동적 쐐기를 사용함으로써 반대측 유방으로의 피폭선량을 감소시킬 수 있었다. 결론적으로 동적 쫴기 기법은 단순히 고정 쐐기를 대체할 수 있을 뿐만 아니라 고정 쐐기의 단점을 보완해 줄 수 있으며 향후 방사선 치료에 있어서 더 다양한 유용성을 가질 수 있으리라 생각한다.

• 대한방사선치료학회지
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• 제14권1호
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• pp.109-116
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• 2002

The mordem linear accelerators are equipped with X-ray collimators that can be moved independently to allow asymmetric fields with field centers positioned away from the true central axis of the beam. We have studied the dosimetric of an independent collimator system using measurements performed quarter fields. The field size factors for asymmetric fields are compared to those for symmetric fields. Dosimetric measurements include portent depth don, beam penumbra and shape of isodose curves for symmetric and quarter fields.

• 대한방사선치료학회지
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• 제11권1호
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• pp.73-78
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• 1999

In general, the patients of the head and neck cancer are treated with 4MV photon beam up to prescribed dose, but spinal cord should be excluded in the treatment field. When its absorbed dose is limited at the tolerance dose. In case of the patients who has the positive posterior neck nodes need a boost electron beam treatment to the prescribed dose. In that case, the anatomical structure of the neck and the physical structure of the standard electron cone interrupt to allow proper access to the disease site. Therefore, we extended treatment SSD for the remove of the those hindrances. In this study, we evaluated the dosimetric variation of the standard electron cone for the extended SSD, from 100cm to 120cm, 5 cm increment, and compare to the custom-made electron cone. As a result, the $\%$ depth dose, the point of maximum dose and the range of maximum were changed within the $2\%$. The penumbra width was increased from 1.0cm to 2.0cm. However, the dosimetric characteristics of the custom-made electron cone was very similar to that of the 100cm SSD standard electron cone and due to its characteristic of physical structure, patients didn't need re-positioning after photon beam treatment, therefore accurate treatment was possible, we conclude that the custom-made electron cone was very useful for the clinical practice.

• 대한방사선치료학회지
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• 제5권1호
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• pp.115-119
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• 1992

The beam characteristics and dosimetric measurements of the 6MV X-ray and 6MeV electron beam from a ML-6M linear accelerator are examined. The Percent Depth Dose(PDD) table and the tissue Maximum Ratio(TMR) table are taken from measurement as a function of the field size and the depth. The calculated TMR table from PDD table is compared with those from measurement. Other beam characteristics such as output factor, beam profile(including flatness, symmetry and penumbra), wedge, and the variation of Dmax are presented. All of these dosimetric measurements sufficiently characterized the beam to permit safe clinical use.

• 한국의학물리학회지:의학물리
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• 제35권1호
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• pp.10-15
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• 2024

Purpose: This study aimed to comprehensively investigate the diverse characteristics of a novel commercial bolus, CLEANBOLUS-WHITE (CBW), to ascertain its suitability for clinical application. Methods: The evaluation of CBW encompassed both physical and biological assessments. Physical parameters such as mass density and shore hardness were measured alongside analyses of element composition. Biological evaluations included assessments for skin irritation and cytotoxicity. Dosimetric properties were examined by calculating surface dose and beam quality using a treatment planning system (TPS). Additionally, doses were measured at maximum and reference depths, and the results were compared with those obtained using a solid water phantom. The effect of air gap on dose measurement was also investigated by comparing measured doses on the RANDO phantom, under the bolus, with doses calculated from the TPS. Results: Biological evaluation confirmed that CBW is non-cytotoxic, nonirritant, and non-sensitizing. The bolus exhibited a mass density of 1.02 g/cm³ and 14 shore 00. Dosimetric evaluations revealed that using the 0.5 cm CBW resulted in less than a 1% difference compared to using the solid water phantom. Furthermore, beam quality calculations in the TPS indicated increased surface dose with the bolus. The air gap effect on dose measurement was deemed negligible, with a difference of approximately 1% between calculated and measured doses, aligning with measurement uncertainty. Conclusions: CBW demonstrates outstanding properties for clinical utilization. The dosimetric evaluation underscores a strong agreement between calculated and measured doses, validating its reliability in both planning and clinical settings.

• 한국의학물리학회지:의학물리
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• 제32권4호
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• pp.159-164
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• 2021

Purpose: We investigated the properties of CLEANBOLUS based on silicone with suitable characteristics for clinical use. Methods: We evaluated the characteristics of CLEANBOLUS and compared the results with the commercial product (Super-Flex bolus). Also, we conducted physical evaluations, including shore hardness, element composition, and elongation break. Transparency was investigated through the measured absorbance within the visible region (400-700 nm). Also, dosimetric characteristics were investigated with surface dose and beam quality. Finally, the volume of unwanted air gap was investigated based on computed tomography images for breast, chin, and nose using Super-Flex bolus and CELANBOLUS. Results: CLEANBOLUS showed excellent physical properties for a low shore hardness (000-35) and elongation break (>1,000%). Additionally, it was shown that CLEANBOLUS is more transparent than Super-Flex bolus. Dosimetric results obtained through measurement and calculation have an electron density similar to water in CLEANBOLUS. Finally, CLEANBOLUS showed that the volume of unwanted air gap between the phantom and each bolus is smaller than Super-Flex bolus for breast, chin, and nose. Conclusions: The physical properties of CLEANBOLUS, including excellent adhesive strength and lower shore hardness, reduce unwanted air gaps and ensure accurate dose distribution. Therefore, it would be an alternative to other boluses, thus improving clinical use efficiency.

• Nuclear Engineering and Technology
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• 제56권7호
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• pp.2516-2523
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• 2024

This study aims to validate the dosimetric characteristics of Low Dose Rate (LDR) I-125 source Geant4-based Monte Carlo code. According to the recommendation of the American Association of Physicists in Medicine (AAPM) task group report (TG-43), the dosimetric parameters of a new brachytherapy source should be verified either experimentally or theoretically before clinical procedures. The simulation studies are very important since this procedure delivers a high dose of radiation to the tumor with only a minimal dose affecting the surrounding tissues. GEANT4 Monte Carlo simulation toolkit associated brachytherapy example was modified, adapted and several updated techniques have been developed to facilitate and smooth radiotherapy techniques. The great concordance of the current study results with the consensus data and with the results of other MC based studies is promising. It implies that Geant4-based Monte Carlo simulation has the potential to be used as a reliable and standard simulation code in the field of brachytherapy for verification and treatment planning purposes.

• 대한방사선치료학회지
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• 제7권1호
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• pp.15-31
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• 1995

The radiosurgery treatment is one time, non surgical approach to the treatment of patients with intracranial disorders whose conditions would be difficult or dangerous to treat with conventional sugical procedures. The LINAC based radiosurgery is based on the combination of multiple isocentric arc irradiation with small fields centered in the stereotactic target. The absorption of the beam in a tissue equivalent medium, such as water, as well as the uniformity, or profile, of the beam must be precisely documented. The beam characteristics and dosimetric measurememts of the 6MV X-ray beam from a ML-6M linear accelerator are examined. The percent depth dose (PDD) and beam profile (including flatness, symmetry and penumbra) is calibrated with the radiosurgery cone in water phantom. The cone is made of lead which size is from $10{\times}10mm{\phi}$ to $30{\times}30mm{\phi}$ All of these dosimetric measurements sufficiently characterized the beam to permit safe clinical use.

• Nuclear Engineering and Technology
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• 제54권1호
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• pp.255-261
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• 2022

A reliable and well-characterized dosimetry system which is traceable to the international measurement system, is the key element to quality assurance in radiation processing with cobalt-60 gamma rays, X-rays, and electron beam. This is specifically the case for health-regulated processes, such as the radiation sterilization of single use medical devices and food irradiation for preservation and disinfestation. Polyethylene is considered to possess a lot of interesting dosimetric characteristics. In this work, a detailed study has been performed to determine the dosimetric characteristics of a commercialized high-density polyethylene (HDPE) film using Fourier transformed infrared spectrometry (FTIR). Correlations have been established between the absorbed dose and radiation induced infrared absorption in polyethylene having a maximum at 965 cm^-1 (transvinylene band) and 1716 cm^-1 (ketone-carbonyl band). We have found that polyethylene dose-response is linear with dose for both bands up to1000 kGy. For transvinylene band, the dose-response is more sensitive if irradiations are made in helium. While, for ketone-carbonyl band, the dose-response is more sensitive when irradiations are carried out in air. The dose-rate effect has been found to be negligible when polyethylene samples are irradiated with electron beam high dose rates. The irradiated polyethylene is relatively stable for several weeks after irradiation.

• Nuclear Engineering and Technology
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• 제55권1호
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• pp.270-277
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• 2023

Exposure to ionizing radiation induces free radicals in human nails. These free radicals generate a radiation-induced signal (RIS) in electron paramagnetic resonance (EPR) spectroscopy. Compared with the RIS of tooth enamel samples, that in human nails is more affected by moisture and heat, but has the advantages of being sensitive to radiation and easy to collect. The fingernail as a biological sample is applicable in retrospective dosimetry in cases of localized hand exposure accidents. In this study, the dosimetric characteristics of fingernails were analyzed in fingernail clippings collected from Korean donors. The dose response, fading of radiation-induced and mechanically induced signals, treatment method for evaluation of background signal, minimum detectable dose, and minimum detectable mass were investigated to propose a fingernail-EPR dosimetry protocol. In addition, to validate the practicality of the protocol, blind and field experiments were performed in the laboratory and a non-destructive testing facility. The relative biases in the dose assessment result of the blind and field experiments were 8.43% and 21.68% on average between the reference and reconstructed doses. The results of this study suggest that fingernail-EPR dosimetry can be a useful method for the application of retrospective dosimetry in cases of radiological accidents.