• 한국원자력학회:학술대회논문집
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• 한국원자력학회 2004년도 요약집 춘계학술발표대회
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• pp.267.1-267.1
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• 2004

• 한국원자력학회:학술대회논문집
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• 한국원자력학회 2002년도 추계학술발표회요약집
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• pp.325.2-325
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• 2002

• Journal of Radiation Protection and Research
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• 제16권1호
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• pp.25-32
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• 1991

MCNP 코드를 사용하여 LAEA에서 권고하고 있는 물팬톰과 미국내 선량계 성능시험 프로그램에서 규정하고 있는 PMMA 펜톰내 0.07mm 및 10mm 깊이에서의 환산인자 H(d)/Ka을 계산하였다. 계산은 팬톰의 한면에 수직으로 입사하는 단일에너지 광자의 확장정열범에 대해 수행하였다. 결과는 팬톰내에서 정의되는 선량당량으로 선량계를 교정할 때 환산인자로 사용될 수 있다.

• 한국산업보건학회지
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• 제28권3호
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• pp.283-291
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• 2018

Objectives: To monitor the radon concentration level in plants that handle phosphorus rock and produce gypsum board and cement, and evaluate the effective dose considering the effect of radon exposure on the human body. Methods: Airborne radon concentrations were measured using alpha-track radon detectors (${\alpha}$-track, Rn-tech Co., Korea) and continuous monitors (Radon Sentinel 1030, Sun Nuclear Co., USA). Radon concentrations in the air were converted to radon doses using the following equation to evaluate the human effects due to radon. H (mSv/yr) = Radon gas concentration x Equilibrium factor x Occupancy factor x Dose conversion factor. The International Commission on Radiological Protection (ICRP) used $8nSv/(Bq{\cdot}hr/m^3)$ as the dose conversion factor in 2010, but raised it by a factor of four to $33nSv/(Bq{\cdot}hr/m^3)$ in 2017. Results: Radon concentrations and effective doses in fertilizer manufacturing process averaged $14.3(2.7)Bq/m^3$ ($2.0-551.3Bq/m^3$), 0.11-0.54 m㏜/yr depending on the advisory authority and recommendation year, respectively. Radon concentrations in the gypsum-board manufacturing process averaged $14.9Bq/m^3$ at material storage, $11.4Bq/m^3$ at burnability, $8.1Bq/m^3$ at mixing, $10.0Bq/m^3$ at forming, $8.9Bq/m^3$ at drying, $14.7Bq/m^3$ at cutting, and $10.5Bq/m^3$ at shipment. It was low because it did not use phosphate gypsum. Radon concentrations and effective doses in the cement manufacturing process were $23.2Bq/m^3$ in the stowage area, $20.2Bq/m^3$ in the hopper, $16.8Bq/m^3$ in the feeder and $11.9Bq/m^3$ in the cement mill, marking 0.12-0.63 m㏜/yr, respectively. Conclusions: Workers handling phosphorous gypsum directly or indirectly can be assessed as exposed to an annual average radon dose of 0.16 to 2.04 mSv or 0.010 to 0.102 WLM (Working Level Month).

• 한국의학물리학회지:의학물리
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• 제21권3호
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• pp.239-245
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• 2010

본 연구의 목적은 직 간접 변환방식 검출기를 사용한 디지털 유방 X선 촬영시스템의 영상 화질을 비교하고 평가함에 있다. 영상의 정량적인 분해능을 나타내는 변조전달함수(MTF), 노이즈 특성을 나타내는 정규화된 잡음력 스펙트럼(NNPS), 그리고 신호 대 잡음비 성능을 나타내는 양자검출효율(DQE)인자를 이용하여 영상 화질평가를 하였다. DQE는 IEC 62220-1-2 규약에 따라 edge 팬텀을 사용한 MTF 도출을 이용하여 계산되었다. 대조도 대 노이즈비(CNR) 측정은 한국의료영상품질관리원에서 제시한 가이드라인에 따라 측정되었다. 직접 변환방식 검출기가 간접 변환방식 검출기에 비해 공간주파수별로 MTF와 DQE 값이 높은 것으로 측정되었다. 동일한 평균유선선량(AGD)일 때 직접 변환방식의 검출기는 더 높은 CNR값을 보였다. 공간주파수별로 높은 DQE 값을 갖는 직접 변환방식 검출기는 디지털 유방 X선 촬영시스템에 있어서 향상된 영상 화질과 적은 환자선량을 제공할 것이다.

• 대한방사선기술학회지:방사선기술과학
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• 제40권4호
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• pp.595-603
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• 2017

본 연구는 파킨슨질환의 진행 정도를 평가할 수 있는 선조체를 모사한 brain 팬텀을 직접 제작하여, PET-CT검사 시 최적의 영상의 질을 유지하면서 CT 스캔에 의한 brain 선량 저감을 위한 가능성을 평가하였다. 팬텀의 hot sphere와 background (radi oacti vi ty rati o 3:1)에 $^{18}F$ FP-CIT를 주입하고, 관전압(100, 120 kVp)과 관전류(80, 140, 200 mAs)의 조건을 변화시키며 CT 스캔을 실험하였다(기준조건; 120 kVp, 140 mAs). 각 조건에 따라 예상유효선량을 conversion factor를 적용해 계산하였고, SNR과 CRChot의 영상평가 인자를 설정하여 영상의 질을 평가하였다. 실험결과 CT 촬영 기준조건 이하에서의 예상유효선량은 최소 10%에서 최고 60% 정도 감소하였고, 기준조건 이상에서의 예상유효선량은 40% 증가하였다. 또한 PET 영상의 SNR과 CRChot의 유의한 차이는 없었으므로, 관전압과 관전류의 감소에 따라 brain 선량이 감소함을 확인하였다. 이와 동시에 스캔 조건의 변화에도 불구하고 SNR과 CRChot 측면에서의 영상의 질에는 유의한 변화가 없었다. 이러한 사실은 낮은 선량 조건으로도 기존의 선량 조건으로 획득한 영상의 질 수준을 얻을 수 있었으므로, 추후 brain PET-CT 스캔의 선량감소와 동시에 영상의 질 향상에 관한 연구의 기초자료로 활용이 가능할 것으로 사료된다.

• Nuclear Engineering and Technology
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• 제54권5호
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• pp.1781-1788
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• 2022

The containment building Kori Unit 1 may require sequential steps for full decommissioning. This study assumes that the containment building is to be used as an auxiliary building that handles nuclear power systems and materials during decommissioning before conversion into a greenfield. Through the derivation of guidelines and dose evaluation, it was confirmed whether the radiation workers were satisfied with the ALARA decision. The specific modeling of the external radiation exposure was performed based on the facility investigation procedures. The external radiation specific derived concentration guideline levels (DCGLs) for radiation workers in containment building were obtained using the RESRAD-BUILD code and were applied to the VISIPLAN 3D ALARA Planning Tool code to calculate the working dose and check worker safety. The derivation of site-specific and realistic DCGLs and dose evaluation via 3D modeling can contribute to the scenario development for the decommission and remediation of containment building.

• 한국의학물리학회:학술대회논문집
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• 한국의학물리학회 2002년도 Proceedings
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• pp.255-259
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• 2002

To reduce the uncertainty in the calibration of radiation beams, absorbed dose to water for high energy electrons is recommended as the standards and reference absorbed dose by AAPM Report no.51 and IAEA Technical Reports no.398. In these recommendations, water is, defined as the reference medium, however, the water substitute solid phantoms are discouraged. Nevertheless, when accurate chamber positioning in water is not possible, or when no waterproof chamber is available, their use is permitted at beam qualities R$\_$50/ < 4 g/cm$^2$ (E$\_$0/ < 10 MeV). For the electron dosimetry using solid phantom, a depth-scaling factor is used for the conversion of depth in solid phantoms to depth in water, and a fluence-scaling factor is used for the conversion of ionization chamber reading in plastic phantom to reading in water. In this work, the properties, especially depth-scaling factors c$\_$p1/ and fluence-scaling factors h$\_$pl/ of several commercially available water substitute solid phantoms were determined, and the electron dosimetry using these scaling method was evaluated. As a result, it is obviously that dose-distribution in solid phantom can be converted to appropriate dose-distribution in water by means of IAEA depth-scaling.

• Nuclear Engineering and Technology
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• 제51권8호
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• pp.1991-1997
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• 2019

In this manuscript, we present a method for the direct calculation of an ambient dose equivalent (H^* (10)) for the external gamma-ray exposure with an energy range of 40 keV to 2 MeV in an electronic personal dosimeter (EPD). The designed EPD consists of a 3 × 3 ㎟ PIN diode coupled to a 3 × 3 × 3 ㎣ CsI (Tl) scintillator block. The spectrum-to-dose conversion function (G(E)) for estimating H^* (10) was calculated by applying the gradient-descent method based on the Monte-Carlo simulation. The optimal parameters for the G(E) were found and this conversion of the H^* (10) from the gamma spectra was verified by using ²⁴¹Am, ¹³⁷Cs, ²²Na, ⁵⁴Mn, and ⁶⁰Co radioisotopes. Furthermore, gamma spectra and H^* (10) were obtained for an arbitrarily mixed multiple isotope case through Monte-Carlo simulation in order to expand the verification to more general cases. The H^* (10) based on the G(E) function for the gamma spectra was then compared with H^* (10) calculated by simulation. The relative difference of H^* (10) from various single-source spectra was in the range of ±2.89%, and the relative difference of H^* (10) for a multiple isotope case was in the range of ±5.56%.

• 한국임상약학회지
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• 제33권4호
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• pp.278-289
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• 2023

Background: Linezolid has been widely used in the treatment for multidrug-resistant tuberculosis. However, there are limitations to use it such as long treatment, because of related side effects, even adequate treatment period has been needed for remission of multidrug-resistant tuberculosis (MDR-TB). Method: The meta-analysis was performed based on Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) criteria. To choose literatures, systematic literature reviews were conducted with databases of PubMed, Web of Science, and EMBASE. Results: Efficacy and safety of Linezolid were determined by 85% (95% CI=79~89%, p<0.05) in the sputum culture conversion and 55% (95% CI=45~64%, p<0.01) in side effects related to linezolid, respectively. In addition, I² was estimated by 72%. In the subgroup analysis, efficacy and safety by dose and region were analyzed. In the subgroup analysis, compared with the linezolid dose in groups greater than 600 mg/day and less than 600 mg/day, this study showed 85% (95% CI 79~90%, p>0.05) in 206 patients and 82% (95% CI 73~89%, p<0.05) in 297 patients, respectively. Also, in the subgroup analysis, adverse effects caused by linezolid occurred more than 50% of treated patients. Conclusion: Therapeutic efficacy of linezolid for MDR-TB patients was confirmed regardless of the initial dose of linezolid, especially for sputum culture conversion and it was recommended that the dose of linezolid has been more effective below 600 mg/day. However, it should be necessary to closely monitored for safety issues since serious side effects possibly occurred by administration of long period treatment.