• The Journal of Korean Institute of Communications and Information Sciences
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• v.32 no.6A
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• pp.565-572
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• 2007

3G Long Term Evolution (3G LTE) is a next generation cellular networks system capable or providing various mobile multimedia services by using OFDMA and MIMO based radio access technology. Among many differences from existing WCDMA based systems, the facts that 3G LTE uses Physical Resource Block (PRB) as its radio resources and provides all services through the PS domain make the development of new resource management schemes necessary. This paper proposes an adaptive partitioning based downlink call admission control scheme. It separates realtime call requests from non-realtime ones, specifies maximum allowable resource amounts for each type, but if the maximum is exceeded, call requests are accepted with probability proportional to remaining resource amounts. Despite the fact that such adaptive concept has been already adopted by other call admission schemes, the contributions of our paper, which are that we are able to find an efficient way to apply the proposed scheme exploiting PRB characteristics and measure the resource usage of base stations by PRB utilization and payload ratio, are still valid. When judging from simulation results in comparison with others, our scheme is able to prioritize realtime call requests over non-realtime ones, and at the same time, overall system performance is superior.

• Journal of Life Science
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• v.22 no.3
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• pp.293-297
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• 2012

The movement of vesicles from the neuronal cell body to specific destinations requires molecular motors. The squid giant axon represents a powerful model for studies of the axonal transport mechanism because the axoplasm can readily be separated from the sheath by simple extrusion. In a previous study, vesicular movements in the axoplasm of the squid giant axon were inhibited by the kinesin antibody. In the present study, we cloned and sequenced the cDNAs for squid brain KIFs. Amplification of the conserved nucleotide sequences of the motor domain by polymerase chain reaction (PCR) using first-strand cDNAs of the squid optic lobe identified six new KIF proteins. Motif analysis of the motor domains revealed that the squid KIFs are homologous to the consensus sequences of the mouse KIFs. The phylogenetic tree generated by using the maximum parsimony (MP) method, the neighbor-joining (NJ) method, the minimum evolution (ME) method, and the maximum likelihood (ML) method showed that squid KIFs are closest to mouse KIFs. These data prove the phylogenetic relationships between squid KIFs and mouse ones.

• Journal of the Korean Magnetics Society
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• v.19 no.5
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• pp.176-179
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• 2009

We report a direct observation of Barkhausen avalanches in 50-nm Fe film, using a magneto-optical microscope magnetometer, capable of time-resolved domain observation. The time-resolved domain-evolution patterns exhibit that the occurrence of Barkhausen jump is random with respect to interval, size, and location. From the repetitive measurements more than 1000 times, we found that the probability distribution of Barkhausen jump size follows a power-law distribution and the critical exponent reveals the value of 1.14 $\pm$ 0.03.

• Structural Monitoring and Maintenance
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• v.1 no.2
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• pp.183-195
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• 2014

Scour is one of the leading causes of overwater bridge failures worldwide. While monitoring systems have already been implemented or are still being developed, they suffer from limitations such as high costs, inaccuracies, and low reliability, among others. Also, most sensors only measure scour depth at one location and near the pier. Thus, the objective is to design a simple, low cost, scour hole topography monitoring system that could better characterize the entire depth, shape, and size of bridge scour holes. The design is based on burying a robust, waterproofed, piezoelectric sensor strip in the streambed. When scour erodes sediments to expose the sensor, flowing water excites it to cause the generation of time-varying voltage signals. An algorithm then takes the time-domain data and maps it to the frequency-domain for identifying the sensor's resonant frequency, which is used for calculating the exposed sensor length or scour depth. Here, three different sets of tests were conducted to validate this new technique. First, a single sensor was tested in ambient air, and its exposed length was varied. Upon verifying the sensing concept, a waterproofed prototype was buried in soil and tested in a tank filled with water. Sensor performance was characterized as soil was manually eroded away, which simulated various scour depths. The results confirmed that sensor resonant frequencies decreased with increasing scour depths. Finally, a network of 11 sensors was configured to form a distributed monitoring system in the lab. Their exposed lengths were adjusted to simulate scour hole formation and evolution. Results showed promise that the proposed sensing system could be scaled up and used for bridge scour topography monitoring.

• Genomics & Informatics
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• v.4 no.4
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• pp.147-160
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• 2006

GATA transcription factors are widespread eukaryotic regulators whose DNA-binding domain is a class IV zinc finger motif in the form $CX_{2}CX_{17-20}CX_{2}C$followed by a basic region. In fungi, they act as transcriptional activators or repressors in several different processes, ranging from nitrogen source utilization to mating-type switching. Using an in-house bioinformatics portal system, we surveyed 50 fungal and 9 out-group genomes and identified 396 putative fungal GATA transcription factors. The proportion of GATA transcription factors within a genome varied among taxonomic lineages. Subsequent analyses of phylogenetic relationships among the fungal GATA transcription factors, as well as a study of their domain architecture and gene structure, demonstrated high degrees of conservation in type IVa and type IVb zinc finger motifs and the existence of distinctive clusters at least at the level of subphylum. The SFH1 subgroup with a 20-residue loop was newly identified, in addition to six well-defined subgroups in the subphylum Pezizomycotina. Furthermore, a novel GATA motif with a 2f-residue loop ($CX_{2}CX_{21}CX_{2}C$, designated 'zinc finger type IVc') was discovered within the phylum Basidiomycota. Our results suggest that fungal GATA factors might have undergone multiple distinct modes of evolution resulting in diversified cellular modulation in fungi.

• Journal of the Korean Society of Marine Environment & Safety
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• v.28 no.1
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• pp.161-167
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• 2022

Ocean waves passing through the underwater bar at a shallow depth experience a shoaling effect caused by decreasing water depth, a nonlinear interaction therein owing to steepening wave slope, and a wave dispersion effect as the water depth increases again. Because this problem includes many complicated phenomena, it is used as a good example of validating a theoretical development or a CFD method for ocean wave applications. Validation is performed mainly for regular waves by comparing the wave elevation patterns in the time domain with the experimental results. In this study, the spectral evolution of wave spectrum is investigated in the frequency domain when a CFD method such as OpenFOAM is applied for this problem. In particular, the effects of initial phase conditions as well as the nonlinear interaction among harmonic waves are studied.

• Molecules and Cells
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• v.45 no.12
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• pp.911-922
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• 2022

A structural protein of SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2), nucleocapsid (N) protein is phosphorylated by glycogen synthase kinase (GSK)-3 on the serine/arginine (SR) rich motif located in disordered regions. Although phosphorylation by GSK-3β constitutes a critical event for viral replication, the molecular mechanism underlying N phosphorylation is not well understood. In this study, we found the putative alpha-helix L/FxxxL/AxxRL motif known as the GSK-3 interacting domain (GID), found in many endogenous GSK-3β binding proteins, such as Axins, FRATs, WWOX, and GSKIP. Indeed, N interacts with GSK-3β similarly to Axin, and Leu to Glu substitution of the GID abolished the interaction, with loss of N phosphorylation. The N phosphorylation is also required for its structural loading in a virus-like particle (VLP). Compared to other coronaviruses, N of Sarbecovirus lineage including bat RaTG13 harbors a CDK1-primed phosphorylation site and Gly-rich linker for enhanced phosphorylation by GSK-3β. Furthermore, we found that the S202R mutant found in Delta and R203K/G204R mutant found in the Omicron variant allow increased abundance and hyper-phosphorylation of N. Our observations suggest that GID and mutations for increased phosphorylation in N may have contributed to the evolution of variants.

• Transactions of the Korean Society for Noise and Vibration Engineering
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• v.26 no.3
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• pp.270-280
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• 2016

This paper investigates the evolution of EM admittance of piezoelectric transducers mounted on a notched beam from wave propagation perspective. A finite element analysis is adopted to obtain numerical solutions for Lamb waves reverberating on the notched beam. The mode-converted Lamb wave signals due to a notch are extracted by using the polarization characteristics of piezoelectric transducers collocated on the beam. Then, a series of temporal spectrums are computed to demonstrate the evolution of EM admittance through fast Fourier transform of the mode-converted Lamb wave signals which are consecutively truncated in the time domain. When truncation time is relatively small, the corresponding temporal spectrum is governed by the characteristics of the input driving frequency. As truncation time becomes large, however, the modal characteristics of the notched beam play a crucial role in the temporal spectrum within the input driving frequency band. This implies that mode-converted Lamb waves reverberating on the beam contributes to the resonance of the beam. The root mean square values are computed for the temporal spectrums in the vicinity of each resonance frequency. The root mean square values increase monotonically with respect to truncation time for any resonance frequencies. Finally the implications of the numerical observation are discussed in the context of damage detection of a beam.

• Journal of Life Science
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• v.11 no.1
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• pp.39-41
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• 2001

Cytohesin family has been thought to participate in inside-outside signaling linking growth factor receptor stimulation of PI 3-kinase to cell adhesion and stimulate nucleotide exchange of ARF through its Sec7 domain. The genomic structure of the cytohesin family was analyzed by BLAST search using cDNA and genomic DNA sequences from the GeneBank database. The cytohesin-2 was encoded by 12 exons. while the cytohesin-4 was encoded by 13 exons. The Sec7 and PH domains were not encoded by separate exons. In an analysis of retroviral integration, those two families did not contain any retroviral elements in introns or exons. The phylogenetic tree calculated by the neighbor-joining method suggests that the cytohesin-1 family was closely related to cytohesin-3 (ARNO3) family. These date could be of great use in further studies for resolving the exact function and evolution of the cytohesin family.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.9 no.4
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• pp.1471-1492
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• 2015

The rapid development of smartphone technologies have resulted in the evolution of mobile botnets. The implications of botnets have inspired attention from the academia and the industry alike, which includes vendors, investors, hackers, and researcher community. Above all, the capability of botnets is uncovered through a wide range of malicious activities, such as distributed denial of service (DDoS), theft of business information, remote access, online or click fraud, phishing, malware distribution, spam emails, and building mobile devices for the illegitimate exchange of information and materials. In this study, we investigate mobile botnet attacks by exploring attack vectors and subsequently present a well-defined thematic taxonomy. By identifying the significant parameters from the taxonomy, we compared the effects of existing mobile botnets on commercial platforms as well as open source mobile operating system platforms. The parameters for review include mobile botnet architecture, platform, target audience, vulnerabilities or loopholes, operational impact, and detection approaches. In relation to our findings, research challenges are then presented in this domain.