• Title/Summary/Keyword: Domain Model

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Implementation of GIS-based Application Program for Circuity and Accessibility Analysis in Road Network Graph (도로망 그래프의 우회도와 접근도 분석을 위한 GIS 응용 프로그램 개발)

  • Lee, Kiwon
    • Journal of the Korean Association of Geographic Information Studies
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    • v.7 no.1
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    • pp.84-93
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    • 2004
  • Recently, domain-specific demands with respect to practical applications and analysis scheme using spatial thematic information are increasing. Accordingly, in this study, GIS-based application program is implemented to perform spatial analysis in transportation geography with base road layer data. Using this program, quantitative estimation of circuity and accessibility, which can be extracted from nodes composed of the graph-typed network structure, in a arbitrary analysis zone or administrative boundary zone is possible. Circuity is a concept to represent the difference extent between actual nodes and fully connected nodes in the analysis zone. While, accessibility can be used to find out extent of accessibility or connectivity between all nodes contained in the analysis zone, judging from inter-connecting status of the whole nodes. In put data of this program, which was implemented in AVX executable extension using AvenueTM of ArcView, is not transportation database information based on transportation data model, but layer data, directly obtaining from digital map sets. It is thought that computation of circuity and accessibility can be used as kinds of spatial analysis functions for GIS applications in the transportation field.

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Facilitation of cisplatin-induced acute kidney injury by high salt intake through increased inflammatory response (염분 섭취에 의한 시스플라틴 유도 급성 신장 손상의 촉진과 염증 반응과의 연관성)

  • Ji, Seon Yeong;Hwangbo, Hyun;Kim, Min Yeong;Kim, Da Hye;Park, Beom Su;Park, Joung-Hyun;Lee, Bae-Jin;Lee, Hyesook;Choi, Yung Hyun
    • Journal of Marine Bioscience and Biotechnology
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    • v.13 no.2
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    • pp.86-93
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    • 2021
  • A high salt diet contributes to kidney damage by causing hypoxia and oxidative stress. Recently, an increase in dietary salt has been reported to induce an inflammatory phenotype in immune cells, further contributing to kidney damage. However, studies on the exact mechanism and role of a high salt diet on the inflammatory response in the kidneys are still insufficient. In this study, a cisplatin-induced acute kidney injury model using C57BL/6 mice was used to analyze the effect of salt intake on kidney injury. Results showed that high salt administration aggravated kidney edema in mice induced by treatment with cisplatin. Moreover, the indicators of kidney and liver function impairment were significantly increased in the group cotreated with high salt compared with that treated with cisplatin alone. Furthermore, the exacerbation of kidney damage by high salt administration was also associated with a decrease in the number of cells in the immune regulatory system. Additionally, high salt administration further decreased renal perfusion functions along with increased cisplatin-induced damage to proximal tubules. This was accompanied by increased expression of T cell immunoglobulin, mucin domain 1 (a biomarker of kidney injury), and Bax (a pro-apoptotic factor). Moreover, cisplatin-induced expression of proinflammatory mediators and cytokines, including cyclooxygenase-2 and tumor necrosis factor-α in kidney tissue, was further increased by high salt intake. Therefore, these results indicate that the kidney's inflammatory response by high salt treatment can further promote kidney damage caused by various pathological factors.

In vitro CaCO3 Crystallization at Room Temperature and Atmospheric Pressure Using Recombinant Proteins GRP_BA and GG1234 (재조합단백질 GRP_BA 및 GG1234를 이용한, 상온상압조건에서의 In vitro 탄산칼슘 결정화)

  • Son, Chaeyeon;Song, Wooho;Choi, Hyunsuk;Choi, Yoo Seong
    • Korean Chemical Engineering Research
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    • v.57 no.2
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    • pp.205-209
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    • 2019
  • The exquisite structure and attractive biological properties of biominerals have great potential and increased interest for use in a wide range of medical and industrial applications. Calcium carbonate biomineralization, mainly controlled by shell matrix proteins, has been used as a representative model to understand the biomineralization mechanism. In this study, in vitro calcium carbonate crystallization was carried out under room temperature and atmospheric pressure using recombinant shell matrix protein GRP_BA and artificial shell matrix protein GG1234. Both proteins inhibited the growth of typical rhombohedral calcite crystals in the calcium carbonate crystallization using $CaCl_2$ solution and $(NH_4)_2CO_3$ vapor, and spherulitic calcite crystals with rosette-like structures were synthesized in both the presence of GRP_BA and GG1234. These results might be caused by the properties of block-like domain structure and intrinsically disordered proteins. We expect that this study can contribute to enhance understanding of the calcium carbonate biomineralization controlled by shell matrix proteins.

A Study on the Efficient Tension Estimation of Cables under Ambient Vibration using Minimized Measurement and Signal Processing System (최소화된 계측 및 신호 처리 시스템을 이용한 상시진동 케이블의 효율적인 장력 추정에 관한 연구)

  • Lee, Hyeong-Jin
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.19 no.11
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    • pp.594-603
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    • 2018
  • Recently, according to the development of measurement techniques, it has become possible to take complicated and time-consuming field measurements in a simple and convenient manner. In this background, this study estimated the tension of cables under ambient vibration using minimized measurement and signal processing. The VBDM using video-only by low-cost equipment was used as a minimized measurement. An estimation of the natural frequency using the mirror frequency concept was also proposed to solve the shortage of frequency band in this case. Furthermore, the FDD method was adopted for a natural frequency estimation in the ambient vibration related to field application. Experimental studies using a cable-stayed bridge model were carried out to examine the properties of the mirror frequency and the applicability of FDD with the proposed minimized system. The results showed that FDD for ambient vibration also works properly in an estimation of the natural frequency using the minimized system. In addition, the mirror frequency concept can allow a high natural frequency estimation even in a distorted signal by low-speed recording, which can overcome the limit of the minimized system. Overall, the proposed minimized system can be effective for the tension estimations of a cable under ambient vibration.

Using Topology Optimization, Light Weight Design of Vehicle Mounted Voltage Converter for Impact Loading (위상 최적화 기법을 이용한 충격하중에 대한 차량 탑재형 전력변환장치의 마운트 경량화 설계)

  • Ko, Dong-Shin;Lee, Hyun-Kyung;Hur, Deog-Jae
    • Journal of the Computational Structural Engineering Institute of Korea
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    • v.31 no.6
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    • pp.353-358
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    • 2018
  • In this study, it is describe to an optimization analysis process for the weight reduction of the voltage converter in the electric vehicle charging systems. The optimization design is a technique that finds the optimal material distribution under a given material quantity constraint by combining the design sensitivity with the material properties and the mathematical optimization. Among the topology optimization, a lightweight design is performed by a solid isotropic material with penalization with simple formula and well-convergence. The lightweight design consists of three steps. As a first step, a finite element model for the basic design of the on-board voltage converter was constructed and static analysis was performed on the load. In the second step, the optimum shape is obtained for the lightweight by performing the topology optimization using the solid isotropic material with penalization applying the stiffness coefficient of the isotropic material to the static analysis result. As a final step, impact analysis was performed by applying a half-sinusoidal pulse shape impact load which satisfies the impact test standard of the vehicle-mounted part with respect to the optimum shape. In the topology optimization, the design domain was defined as the mounting bracket area, and the design technology was finally achieved by optimizing the mounting bracket to achieve a weight reduction of 20% over the basic design.

The Method for Colorizing SAR Images of Kompsat-5 Using Cycle GAN with Multi-scale Discriminators (다양한 크기의 식별자를 적용한 Cycle GAN을 이용한 다목적실용위성 5호 SAR 영상 색상 구현 방법)

  • Ku, Wonhoe;Chun, Daewon
    • Korean Journal of Remote Sensing
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    • v.34 no.6_3
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    • pp.1415-1425
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    • 2018
  • Kompsat-5 is the first Earth Observation Satellite which is equipped with an SAR in Korea. SAR images are generated by receiving signals reflected from an object by microwaves emitted from a SAR antenna. Because the wavelengths of microwaves are longer than the size of particles in the atmosphere, it can penetrate clouds and fog, and high-resolution images can be obtained without distinction between day and night. However, there is no color information in SAR images. To overcome these limitations of SAR images, colorization of SAR images using Cycle GAN, a deep learning model developed for domain translation, was conducted. Training of Cycle GAN is unstable due to the unsupervised learning based on unpaired dataset. Therefore, we proposed MS Cycle GAN applying multi-scale discriminator to solve the training instability of Cycle GAN and to improve the performance of colorization in this paper. To compare colorization performance of MS Cycle GAN and Cycle GAN, generated images by both models were compared qualitatively and quantitatively. Training Cycle GAN with multi-scale discriminator shows the losses of generators and discriminators are significantly reduced compared to the conventional Cycle GAN, and we identified that generated images by MS Cycle GAN are well-matched with the characteristics of regions such as leaves, rivers, and land.

North Korea's Cyber Attack Patterns and Behaviors : An Analysis Based on Cyber Power and Coercion Theory (북한의 대남 사이버공격 양상과 행태 : 사이버파워와 강압이론을 통한 분석)

  • Yoon, Taeyoung;Woo, Jeongmin
    • Convergence Security Journal
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    • v.18 no.1
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    • pp.117-128
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    • 2018
  • The purpose of this paper is to analyze the behavior of North Korea's cyber attack against South Korea since 2009 based on major international security theories and suggest South Korea's policy option. For this purpose, this paper applied the behavioral domain and characteristics of 'cyber power' and 'coercion dynamics' model, which are attracting attention in international security studies. The types of cyber attacks from North Korea are classified into the following categories: power-based incarceration, leadership attacks and intrusions, military operations interference, and social anxiety and confusion. In terms of types and means of cyber power, North Korean GPS disturbance, the Ministry of Defense server hacking and EMP are hard power with high retaliation and threat and cyber money cashing and ransomware are analyzed by force in the act of persuasion and incentive in the point of robbing or asking for a large amount of money with software pawns. North Korea 's cyber attack has the character of escape from realistic sanctions based on the second nuclear test. It is important for South Korea to clearly recognize that the aggressive cyberpower of North Korea is changing in its methods and capabilities, and to ensure that North Korea's actions result in far greater losses than can be achieved. To do this, it is necessary to strengthen the cyber security and competence to simultaneously attack and defend through institutional supplement and new establishment such as cyber psychological warfare, EMP attack preparation, and enhancement of security expertise against hacking.

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Fine mapping of rice bacterial leaf blight resistance loci on K1 and K2 of Korean races of Xoo (Xanthomonas oryzae) using GWAS analysis

  • Hyeon, Do-Yun;Lee, Jeong-Ro;Jo, Gyu-Taek;Raveendar, Sebastin;Sin, Myeong-Jae;Lee, Gyeong-Jun
    • Proceedings of the Plant Resources Society of Korea Conference
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    • 2019.04a
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    • pp.62-62
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    • 2019
  • Bacterial leaf blight(BLB), caused by X. oryzae pv. oryzae(Xoo), is one of the most destructive diseases of rice due to its high epidemic potential. Understanding BLB resistance at a genetic level is important to further improve the rice breeding that provides one of the best approaches to control BLB disease. In the present investigation, a collection of 192 accessions was used in the genome-wide association study (GWAS) for BLB resistance loci against four Korean races of Xoo that were represented by the prevailing BLB isolates under Xoo differential system. A total of 192 accessions of rice germplasm were selected on the basis of the bioassay using four isolated races of Xoo such as K1 and K2. The selected accessions was used to prepare 384-plex genotyping by sequencing (GBS) libraries and Illumina HiSeq 2000 pairedend read was used for GBS sequencing. GWAS was conducted using TASSEL 5.0. The TASSEL program uses a mixed linear model (MLM). The results of the bioassay using a selected set of 192 accessions showed that a large number of accessions (93.75%) were resistant to K1 race and K2 resistant germplasm proportion remained between 66.67. The genotypic data produced SNP matrix for a total of 293,379 SNPs. After imputation the missing data was removed, which exhibited 34,724 SNPs for association analysis. GWAS results showed strong signals of association at a threshold of [-log10(P-value)] more than 5 (K1 and K2) for nine of the 39 SNPs, which are plausible candidate loci of resistance genes. These SNP loci were positioned on rice chromosome 2, 9, and 11 for K1 and K2 races. The significant loci detected have also been illustrated and make the CPAS markers for NBS-LRR type disease resistance protein, SNARE domain containing protein, Histone deacetylase 19, NADP-dependent oxidoreductase, and other expressed and unknown proteins. Our results provide a better understanding of the distribution of genetic variation of BLB resistance to Korean pathogen races and breeding of resistant rice.

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Secure Training Support Vector Machine with Partial Sensitive Part

  • Park, Saerom
    • Journal of the Korea Society of Computer and Information
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    • v.26 no.4
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    • pp.1-9
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    • 2021
  • In this paper, we propose a training algorithm of support vector machine (SVM) with a sensitive variable. Although machine learning models enable automatic decision making in the real world applications, regulations prohibit sensitive information from being used to protect privacy. In particular, the privacy protection of the legally protected attributes such as race, gender, and disability is compulsory. We present an efficient least square SVM (LSSVM) training algorithm using a fully homomorphic encryption (FHE) to protect a partial sensitive attribute. Our framework posits that data owner has both non-sensitive attributes and a sensitive attribute while machine learning service provider (MLSP) can get non-sensitive attributes and an encrypted sensitive attribute. As a result, data owner can obtain the encrypted model parameters without exposing their sensitive information to MLSP. In the inference phase, both non-sensitive attributes and a sensitive attribute are encrypted, and all computations should be conducted on encrypted domain. Through the experiments on real data, we identify that our proposed method enables to implement privacy-preserving sensitive LSSVM with FHE that has comparable performance with the original LSSVM algorithm. In addition, we demonstrate that the efficient sensitive LSSVM with FHE significantly improves the computational cost with a small degradation of performance.

A vision-based system for long-distance remote monitoring of dynamic displacement: experimental verification on a supertall structure

  • Ni, Yi-Qing;Wang, You-Wu;Liao, Wei-Yang;Chen, Wei-Huan
    • Smart Structures and Systems
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    • v.24 no.6
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    • pp.769-781
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    • 2019
  • Dynamic displacement response of civil structures is an important index for in-construction and in-service structural condition assessment. However, accurately measuring the displacement of large-scale civil structures such as high-rise buildings still remains as a challenging task. In order to cope with this problem, a vision-based system with the use of industrial digital camera and image processing has been developed for long-distance, remote, and real-time monitoring of dynamic displacement of supertall structures. Instead of acquiring image signals, the proposed system traces only the coordinates of the target points, therefore enabling real-time monitoring and display of displacement responses in a relatively high sampling rate. This study addresses the in-situ experimental verification of the developed vision-based system on the Canton Tower of 600 m high. To facilitate the verification, a GPS system is used to calibrate/verify the structural displacement responses measured by the vision-based system. Meanwhile, an accelerometer deployed in the vicinity of the target point also provides frequency-domain information for comparison. Special attention has been given on understanding the influence of the surrounding light on the monitoring results. For this purpose, the experimental tests are conducted in daytime and nighttime through placing the vision-based system outside the tower (in a brilliant environment) and inside the tower (in a dark environment), respectively. The results indicate that the displacement response time histories monitored by the vision-based system not only match well with those acquired by the GPS receiver, but also have higher fidelity and are less noise-corrupted. In addition, the low-order modal frequencies of the building identified with use of the data obtained from the vision-based system are all in good agreement with those obtained from the accelerometer, the GPS receiver and an elaborate finite element model. Especially, the vision-based system placed at the bottom of the enclosed elevator shaft offers better monitoring data compared with the system placed outside the tower. Based on a wavelet filtering technique, the displacement response time histories obtained by the vision-based system are easily decomposed into two parts: a quasi-static ingredient primarily resulting from temperature variation and a dynamic component mainly caused by fluctuating wind load.