• Title/Summary/Keyword: Dog-bone

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Guided Bone Regeneration with a PDGF-BB-Ioaded Resorbable Membrane in the Dehisced Implant of the Beagle Dog (치아매식술에 이용한 혈소판 유래 성장인자 함유 흡수성 차폐막의 골유도 재생효과)

  • Kwon, Young-Hyuk;Park, Joon-Bong;Herr, Yeek;Chung, Chong-Pyung;Han, Soo-Bog;Lee, Seung-Jin
    • Journal of Periodontal and Implant Science
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    • v.28 no.3
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    • pp.431-451
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    • 1998
  • 4 beagle dogs aged over one and half years and weighed 15 to 16 Kg were utilized in this study. Experimental dehiscent defects were made in the mandibular edentulous area after removal of lower premolar. e-PTFE membrane resorbable membrane, and PDGF-BB-loaded resorbable membrane were covered at the dehiscent defects around the dental implants respectively. Animal was sacrificed at 1, 2, 3 months respectively. Non-decalicifed specimens were made and mutiple-stained for light microscopic study. The results were as follows: 1. Dehiscent defects around the implant installed in the beagle dog were an excellent defect model for studying guided bone regeneration. 2. Fibroblasts penetrated into expanded-PTFE membrane was observed and inflammatory cell infiltration was also observed around the membrane. 3. Resorbable membrane was degradaded and resorbed at 1 month after application to the dehiscent defect. Though multinucleated giant cells were observed adjacent to the membrane, that had no reverse effect on the boe regeneration. 4. PDGF-BB-Ioaded resorbable membrane was same capability as the resorbable membrane and e-PTFE membrane in the guided bone regeneration. 5. PDGF-BB-Ioaded resorbable membrane-applied site was better than resorbable membrane-applied site in the speed and maturity of bone formation. Within the above results, it was suggested that PDGF-BB-Ioaded resorbable membrane might have same bone regeneration capacity as nonresorbable membrane in the dehisced implant of the beagle dog and potentiality to use in human subjects.

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Clinical Effect of Guide Bone Regeneration of Mandibular Nonunion in a Geriatric Dog (노령견의 하악골절 불유합 1례에서 골유도재생술의 임상적 효과)

  • Kim, Se-Eun;Shim, Kyung-Mi;Bae, Chun-Sik;Choi, Seok-Hwa;Jeong, Soon-Jeong;Kang, Seong-Soo
    • Journal of Veterinary Clinics
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    • v.30 no.2
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    • pp.127-130
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    • 2013
  • A 13-year-old, 4.2 kg female poodle was referred for failure of first bilateral mandibular surgery at a local animal hospital after pathologic fracture. Surgery was performed with 2.0-mm miniplates/screws and porcine cancellous bone grafts. In addition, because of the large size of the right segmental defect, a barrier absorbable membrane was employed for guide bone regeneration on right mandible. After surgery, follow-ups performed at 1 day, 1, 4, 8, and 12 weeks; there were no signs of dental malocclusion, nonunion or soft tissue infection. However, a 1-year long-term follow-up showed nonunion in the left mandibular fracture site for which a collagen membrane had not been used. It is considered that use of porcine bone graft with barrier absorbable membrane may be effective for the repair of mandibular nonunion in a geriatric dog.

The experimental study of early loading on the Miniplate in the beagle dog (성견의 하악골에 식립된 Miniplate에 가한 조기 부하의 영향에 관한 실험적 연구)

  • Chung, Yong-Koo;Lee, Young-Jun;Chung, Kyu-Rhim
    • The korean journal of orthodontics
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    • v.33 no.4 s.99
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    • pp.307-317
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    • 2003
  • Conventional osseointegrated titanium implants have many limitations; large size, limited location for placement of the implant, severity of the surgery, discomfort of initial healing, difficulty of oral hygiene and uncontrollable force direction. Recently titanium miniscrew and miniplate have been used for an alternative to conventional dental implant. But in relation to miniplate, miniscrew has disadvantages in that more potential inflammation, light orthodontic force application and limited orthodontic application. This study was conducted to evaluate the effectiveness of miniplate by observing the reactions of peri-implant tissues to early orthodontic and orthopedic loading of titanium miniplate. In four adult beagle dogs 10 miniplates were inserted into the alveolar bone using 20 osseointegrated titanium screws. 4 miniplates were placed in two dogs(dogA, B) and 6 miniplates in two dogs(dogC, D). In dogA, B miniplates were loaded with 200gm of force immediately after placement for 15 weeks. In dogc, D, miniplates were loaded with 400gm of force immediately after placement for 8 weeks. Miniplates of dogA were removed, dogA was healed for 4 weeks, and the area which was removed of miniscrew was examined. Following an observation period, the miniplates including miniscrews and the surrounding bone of dogB and dogC, D were removed, respectively. Undecalcified section along the long axis of miniscrews were made and the degree of osseointegration was examined under the light microscope. The results were as follows. 1. In the histologic features there was direct contact between bone and miniscrew in all groups except one, dogC control group. The loaded miniscrew demonstrated only a slight increase of the osseous proximaty when compared with unloaded miniscrew 2. There was no significant difference of the osseointegration of Peri-miniscrew surface between dogB and dogC, D. But dogB showed slightly more increased bone apposition than dogC, D 3. The gingiva overlapping the miniplate and miniscrew showed no inflammatory sign in clinical and histological aspects. 4. The impaled hard and soft tissues at the area which was removed of miniscrews showed good healing without inflammatory reaction. 5. The mobility showed slight increase in un-loaded miniplate but that was insignificant. Based on the results of this study, miniplate(C-tube) can be used as a firm osseous orthodontic and orthopedic anchorage unit immediately after insertion.

Bone Alkaline Phosphatase Levels in Serum of Normal Dogs (정상적인 개에서의 Serum Bone Alkaline Phosphatase의 활성치)

  • 조성진;김남수;최인혁
    • Journal of Veterinary Clinics
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    • v.14 no.1
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    • pp.65-69
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    • 1997
  • The bone alkaline phosphatase(BALP) in 130 sera of normal dogs were assayed according to the lectin precipitation method of Rosalki and Foo. The serum BALP activities showed a wide variation as $23.27({\pm}14.73)$ IU/L in young dogs from 6weeks to 12 months old and were lower in magnitude as $9.24({\pm}3.36)$ IU/L in elder dogs from 1 years to 6years old. The serum BALP activities in normal dogs were no significant correlation in sex.

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A Successful Management of an Esophageal Perforation Caused by Esophageal Foreign Body with a Non-operative Treatment in a Dog (개에서 식도 이물에 의한 식도 천공의 비침습적 치료를 통한 성공적 관리 증례)

  • Lee, Hyeon-Suk;Baek, Dae-Seung;Ju, Ho-Jong;Kim, Jun-Hwan;Hong, Yeon-Jung;Park, Jin-Ho;Cho, Ho-Seong;Park, Chul
    • Journal of Veterinary Clinics
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    • v.29 no.6
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    • pp.506-508
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    • 2012
  • A 5-year-old, intact female, Pomeranian was presented with a persistent vomiting for 5 days after swallowing a chicken bone. The dog was diagnosed with an esophageal foreign body, and a small perforation was found after the endoscopic removal of the chicken bone. The dog was determined to be treated with a non-operative management, and a complete closure of the perforation was confirmed by a flexible endoscopy 3 weeks after removal of a chicken bone. This paper reports the case of esophageal perforation caused by foreign body in esophagus managed with the non-operative therapy instead of surgical correction.

Multilobular Osteochondrosarcoma of the Cranium in a Miniature Pinscher Dog

  • Kim, Soo-Chan;Lee, Jung-Woo;Jeong, Woo-Chang;Song, Ha-Na;Choi, Soo-Young;Choi, Ho-Jung;Lee, Young-Won
    • Journal of Veterinary Clinics
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    • v.34 no.6
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    • pp.470-473
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    • 2017
  • An eight-year old neutered male miniature pinscher dog was referred with a mass on the right frontal region. Radiography, computed tomography (CT) and magnetic resonance imaging (MRI) examination were performed. Imaging results showed mineralized mass invaded frontal bone without brain parenchymal change and distant metastasis. The mass was removed mostly by surgical resection, and the dog was discharged without any complications. On the histopathological examination, the mass was diagnosed as grade I multilobular osteochondrosarcoma. Though the mass recurred after the surgical resection, the dog is still alive to date without metastasis.

A HISTOLOGICAL STUDY OF THE ROOT RESORPTION APPLYING TO INTERMITTENT AND CONTINUOUS FORCE FOR INCISOR INTRUSION OF DOG (성견의 전치부 INTRUSION시 간헐적 교정력과 지속적 교정력의 적용에 따른 치근 흡수에 관한 실험적 연구)

  • Chang, Ji-Chul;Park, Young-Chul
    • The korean journal of orthodontics
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    • v.22 no.1
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    • pp.241-251
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    • 1992
  • The purpose of this study was to investigate the root resorption pattern in incisors in dog under intrusive orthodontic loadings of various magnitude and duration. Intrusive forces were generated by closed coil springs. Force magnitudes were 15-30gm, 50-60gm and 80-110gm. Durations were continuous and intermittent. Intermittent duration was applied at intervals of 12 hours. The readjustment of the force was done every 4 days. The forces were maintained for 30 days. All specimens were decalfied, embedded in paraffin and stained with hematoxylin-eosin stain. Observations were made with light microscope. The following results were obtained; 1. The continuity of root surface was ceased in all, except intermittent forced teeth with 25gm. 2. The root resorptions, cementoclasts and cemental lacunae, were increased around periapical regions and the destructive scope of bone was deeply extended as the exerted orthodontic forces increased. 3. It was inspected that, under the same forces, root resorption and bone destruction were more deeply appeared in the continuously forced teeth than the intermittently forced ones. 4. All of the alveolar bone, showed direct and undermining bone resorptions.

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Tissue Responses Around Two Types of Dental Implant in Beagle Dog (두 종류의 치과 임플란트 식립후 조직의 반응에 대한 비교연구)

  • Chung, Hyung-Geun;Kwon, Young-Hyuk;Lee, Man-Sup;Park, Joon-Bong
    • Journal of Periodontal and Implant Science
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    • v.29 no.4
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    • pp.929-942
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    • 1999
  • Three beagle dogs aged over one and half years were used in this study. All mandibular premolars were carefully extracted. Two AVANA implants(Sumin, Korea) and two 3i implants(Implant Innovation, USA) were installed at each right and left side respectively. Each dog was sacrificed at 4, 8. 12 weeks. Non-decalcified specimens were made and stained for a light microscopic study. The results were as follows ; 1. Inflammation was not observed in the area of bone tissue adjacent to the implant body. 2. With time, quantity of osseointe-gration increased in each type of den-dental implant. There was no difference between AVANA implant and 3i implant. 3. Maturation of the bone around each type of the dental implant increased with time. 12 weeks after implant installation, the bone around dental implant represented compact bone-like appreance. 4. In case implants were located adjacent to a root, newly-formed periodontal ligament tissue was observed around the implant. And the direction of the periodontal ligament fiber was parallel to the surface of the implant . Within the results of this study, AVANA implants represented similar osseointegra-tion in comparision with 3i implants.

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The Use of a Porcine Cancellous Bone Graft for Arthrodesis of Bilateral Antebrachiocarpal Luxation in a Dog (양측 전완앞발목관절 탈구의 관절고정술을 위한 돼지뼈 해면골이식의 적용)

  • Heo, Su-Young;Lee, Ki-Chang;Kim, Nam-Soo
    • Journal of Veterinary Clinics
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    • v.29 no.3
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    • pp.259-262
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    • 2012
  • A seven-year-old Yorkshire terrier 2.1 kg was admitted with a 2 months history of sever bilateral forelimb lameness and joint instability. Examination and radiographs revealed caudal luxation of bilateral antebrachiocarpal joint. Luxation of bilateral antebrachiocarpal (ABC) joint in a toy breed dog was treated with pancarpal arthrodesis. Modified external skeletal fixator (ESF) (type IIb) with polymethylmethacrylate (PMMA) was utilized in this case. Porcine cancellous bone graft (PCBG) was inserted to fill the joint space in carpus. The clinical and radiographic assessments of joint after the surgical procedure proved that PCBG can be used a promising alternative to Autogenous cancellous bone graft (ACBG).