• Title/Summary/Keyword: Docosahexaenoic acid

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Effects of Dietary Polyunsaturated Fatty Acids on Tocopherol Contents and Lipid Peroxidation of Plasma and Tissues in Rats Fed High Fat Diet (고지방식이에서 서로 다른 불포화 지방산 섭취가 쥐의 혈청과 조직의 Tocopherol함량과 지질과산화물 형성에 미치는 영향)

  • 남정혜
    • The Korean Journal of Food And Nutrition
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    • v.7 no.4
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    • pp.373-382
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    • 1994
  • This study was observed the effect of n6 and n3 polyunsaturated fatty acids of dietary corn oil and fish oil which was supplemented with similar levels of tocopherol in high fat diet on the levels of tocopherol, malondialdehyde ( MDA) productions of plasma and tissues of rats. Also RBC hemolysis, superoxide dismutase (SOD) and glutathione peroxidase (GSH Px) activities In liver were determined. Male Sprague Dawley rats were fed high fat (40%Cal) diet which was different only In fatty acid composition for 6 weeks. Dietary (arts were beef tallow(BT) as a source of saturated fatty acid, corn oil(CO) for n6 linoleic acid (LA) and fish oil(FO) for n3 eicosapentaenoic acid(EPA) + docosahexaenoic acid (DHA). Plasma and liver tocopherol levels were lowered by n3 PUy4 but there was no difference in malondialdehyde(MDA) level by different dietary PUFA. However, MDA content of RBC and hemolysis were increased by n3 PUFA. MDA content, superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) activities in liver were increased in more unsaturated dietary fat groups. Especially, SOD activity was increased in proportion to the degree of fat unsaturation.

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Evaluation of Dietary Supplementation with Linseed Oil for Juvenile Atlantic Bluefin Tuna Thunnus thynnus (치어기 대서양참다랑어(Thunnus thynnus) 사료 내 아마인유의 이용성 평가)

  • Seung-Cheol Ji;Jongho Lim;Jaehyeong Shin;Kyeong-Jun Lee
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.56 no.5
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    • pp.741-748
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    • 2023
  • This study evaluated the supplemental effects of linseed oil (LO) as a substitute for docosahexaenoic acid oil (DHAO) in the diet of juvenile Atlantic bluefin tuna. A control diet (DHA) was formulated to contain 65% enzyme-treated fish meal and 3% of DHAO. A LO diet was formulated to contain 1% LO replacing 1% DHAO in DHA diet. In a feeding trial, 300 juvenile bluefin tuna (initial body weight 1.15 g) were randomly divided into two concrete tanks (70 ton capacity) and fed one of the experimental diets for 13 days. Weight gain was higher in the LO group (519%) than in the control (443%) while survival and protein digestibility were similar between groups. The biological assessment of the tuna digestive organs did not differ between the DHA and LO groups. The fatty acid composition of the carcass showed that α-linolenic acid was only observed in the LO group, and there was no difference in the composition of eicosapentaenoic acid and docosapentaenoic acid between the groups. These results indicate that LO could be a dietary good oil source for Atlantic bluefin tuna without apparent negative effects.

Prediction of Daphnia Production along a Trophic Gradient

  • Park, Sang-Kyu;Goldman, C.R.
    • Journal of Ecology and Environment
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    • v.31 no.2
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    • pp.125-129
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    • 2008
  • To predict Daphnia secondary productivity along a trophic gradient indexed as total phosphorus (TP) concentration, we estimated energy transfer efficiencies from food quality for Daphnia such as eicosa-pentaenoic acid (EPA) or docosahexaenoic acid (DHA) content. Eleven flow-through Daphnia magna growth experiments were conducted with seston from 9 lakes, ponds and river waters. Primary productivities were estimated from food supply rates in the flow-through experiments, producing energy transfer efficiencies from seston to D. magna. We found DHA content was the best predictor of energy transfer efficiencies among the essential fatty acids. An asymptotic saturation model explained 79.6% of the variability In energy transfer efficiencies. Based on empirical data in this study and empirical models from literature, we predict that Daphnia productivity would peak in mesotrophic systems by decreasing food quality and Increasing food quantity along trophic gradient.

Analytical Studies of Constituents of Antlers (녹용류의 성분 분석 연구)

  • Ha, Hun;Yoon, Soo-Hong
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.25 no.2
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    • pp.279-282
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    • 1996
  • 동양의학에서 강정 강장제로서의 귀히 여겨지는녹용의 유효성분과 또한 녹각과 그 유효성의 차이를 찾기 위해 무기질, 아미노산과 지방산 조성 등을 비교 검토하였다. 무기질 조성은 녹용과 녹각에서 Ca의 함량이 제일 높았고, Na과 K 함량도 상당히 높았으며 Hg 등 중금속은 전혀 검출되지 않았으며, 녹각에서는 Mn과 Fe이 미량 검출되었다. 녹용의 지방산은 포화지방산보다 불포화지방산 함량이 월등히 높았으며 그 중에서도 동맥경화증을 경감시킨다고 하는 docosahexaenoic acid가 43.73%로 제일 높았고, 녹각에서는 녹용에 비해 전반적으로 함량이 낮았다. 아미노산은 녹용에서 총 17종이 검출되었는데, glycine 함량이 제일 높았고, alanine과 proline 순이었다. 이는 collagen이 녹용의 상당부분을 차지한다는 것을 시사하며, 녹각에서는 비록 함량은 적었지만 10종이 검출되었으며, glutamic acid, proline, glycine과 alanine 등도 상당히 함유되어 있었다.

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Effect of Menhaden Oil Feeding on Protein Kinase C Activity and Membrane Phospholipid Profiles in Mouse Epidermal Cells (지방질원으로서 어유가 백서 상피세포의 인지질 조성 및 Protein Kinase C 활성에 미치는 영향)

  • Choe, Myeon
    • Journal of Nutrition and Health
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    • v.27 no.5
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    • pp.419-428
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    • 1994
  • To investigate the effect of dietary menhaden oil on protein kinase C (PKC) activity and membrane phospholipid composition in epidermal cells, female BALB/C mice were fed either menhaden oil or corn oil with two different levels(5% or 20%) for 6 weeks. Membrane phosphatidycholine(PC) was decreased in menhaden oil-fed group. Eicosapentaenoic acid(EPA) and Docosahexaenoic acid(DHA) were only presented in the acyl chain of membrane phospholipid of menhaden oil-fed mice, so that membrane fluidity of the group could be different from the other group. Both cytosolic and membrane-associated PKC activity in epidermal cells were decreased in menhaden oil-fed mice when compare with corn oil-fed mice. Furthermore, rate of PKC transfer from cytosol to membrane in menhaden oil-fed group was not as fast as in corn oil-fed group. Based on these observations, dietary menhaden oil might act differently from other dietary fat in carcinogenesis.

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Molecular Species Composition of Phosphatidylcholine Isolated from Chum Salmon Meat Oil

  • Lee, Seung-Joo;Ha, Wang-Hyun;Choi, Hye-Jin;Cho, Soon-Yeong
    • Fisheries and Aquatic Sciences
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    • v.13 no.3
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    • pp.206-209
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    • 2010
  • Chum salmon (Oncorhynchus keta) meat oil contained high amounts of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) compared to oils extracted from other tissues of the fish. EPA and DHA occupied more than 25% of the total fatty acids in chum salmon meat oil. The main lipid classes in the meat oil were triacylglycerides and phospholipids. The major fatty acids of the molecular species composition of phosphatidylcholine isolated from the meat oil were DHA and EPA. DHA and EPA were the major molecular species in the phosphatidylcholine of chum salmon meat oil, representing 44% and 17%, respectively.

Calcium-alginate gel을 이용한 DHA유의 캡슐화

  • Yoon, Young-Soo;Kwak, Ki-Seok;Lee, Ju-Hang;Cho, Sang-Won;Lee, Won-Dong;Jeon, Byung-Jun;Lee, Sung;Ji, Chung-Il;Kim, Sang-Ho;Lee, Yang-Bong;Kim, Sun-Bong
    • Proceedings of the Korean Society of Fisheries Technology Conference
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    • 2001.10a
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    • pp.169-170
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    • 2001
  • 등푸른 생선 등에 많은 eicosapentaenoic acid(EPA, $C_{20-5}$ n-3), docosahexaenoic acid(DHA, $C_{22-6}$ n-3)등의 n-3계 지방산은 순환기 계통 질환의 위험인자를 제거해 주거나 혈청내 지질 구성이나 혈소판응집 기능에 변화를 주어 동맥경화증에 유익한 효과를 나타낸다고 알려져 있다. 특히 DHA는 망막 및 두뇌 인지질의 구성성분으로 실험동물의 학습능을 비롯한 뇌기능 향상에 기여한다고 한다. (중략)략)략)

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Separation of Tetrodotoxin, DHA and EPA from Pufferfish Liver Waste (복어간 폐기물로부터 Tetrodotoxin, DHA 및 EPA의 분리)

  • 차병윤;최진석;임정규;이동익;이원갑;이은열;김희숙;김동수
    • Journal of Life Science
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    • v.10 no.2
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    • pp.115-124
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    • 2000
  • The present study was undertaken to separate the available components effectively, such as tetrodotoxin(TTX), docosahexaenoic acid(DHA, C22:6,ω-3) and eicosapentaenoic acid (EPA, C20:5,ω -3) from pufferfish liver waste, which are known to have high values as bioactive materials. By using ultrafiltration, it was possible to separate high contents of 68mg TTX from pufferfish liver waste. In contrast, by activated charcoal column, it was to obtain about 54mg TTX. The recovering ratios were 65.3% and 45.0% in the two different methods of ultrafiltration and activated charcoal column, respectively. From the results of HPLC and gas chromatography-mass spectrometry(GC-MS), the obtained toxins were identified to be TTX and its derivatives. In addition, it was also possible to obtain 72.3g DHA and 11.4g EPA from 1kg of pufferfish liver by high performance liquid chromatography (HPLC). These amounts of DHA and EPA were also 17.70% and 1.04% in the total lipid of pufferfish liver oil from analysis of gas chromatography(GC), respectively.

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Analysis of Biochemical Compositions and Nutritive Values of Six Species of Seaweeds (해조류 6종의 생화학적 조성 및 영양적 가치 분석)

  • Kim, Donggiun;Park, Jongbum;Lee, Taek-Kyun
    • Journal of Life Science
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    • v.23 no.8
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    • pp.1004-1009
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    • 2013
  • The biochemical compositions and nutritive values of six species of seaweeds were analyzed to determine their applicability in functional foods or ingredients. The biochemical compositions (moisture, ash, protein, lipid, and dietary fiber) and fatty acid contents were determined for the following seaweed extracts: Phaeophyceae (Laminaria japonica, Hizikia fusiformis, and Undaria pinnatifida), Rhodophyceae (Porphyra tenera and Gracilaria verrucosa), and Chlorophyceae (Ulva lactuca). The moisture content (% dry weight) ranged from 11.47% to 13.94%, ash from 19.15% to 26.50%, protein from 5.08% to 15.44%, lipid from 2.75% to 4.43%, and dietary fiber from 36.84% to 52.98%. C14:0, C16:0, C18:0, C16:1, C18: 1n-3, C18:2n-6, C18:3n-6, C20:4n-6, and C20:5n-3 represented the predominant proportions of fatty acids. Interestingly, docosahexaenoic acid (C22:6n-3, DHA) was either not found or only detected in trace amounts in the analyzed seaweeds. The levels of n-3 fatty acid were higher than other polyunsaturated fatty acids, and the n-6/n-3 ratio was very low. These results indicate that seaweed inhabiting Korean coastal areas will be beneficial to human health.