• Journal of KIISE:Computer Systems and Theory
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• v.35 no.6
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• pp.237-247
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• 2008

A virtual screening is the process of reducing an unmanageable number of compounds to a limited number of compounds for the target of interest by means of computational techniques such as molecular docking. And it is one of a large-scale scientific application that requires large computing power and data storage capability. Previous applications or softwares for molecular docking such as AutoDock, FlexX, Glide, DOCK, LigandFit, ViSION were developed to be run on a supercomputer, a workstation, or a cluster-computer. However the virtual screening using a supercomputer has a problem that a supercomputer is very expensive and the virtual screening using a workstation or a cluster-computer requires a long execution time. Thus we propose a service-based virtual screening system using Grid computing technology which supports a large data intensive operation. We constructed 3-dimensional chemical molecular database for virtual screening. And we designed a resource broker and a data broker for supporting efficient molecular docking service and proposed various services for virtual screening. We implemented service based virtual screening system with DOCK 5.0 and Globus 3.2 toolkit. Our system can reduce a timeline and cost of drug or new material design.

• Journal of Advanced Research in Ocean Engineering
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• v.1 no.3
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• pp.148-156
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• 2015

Deck plates of ships or offshore structures would make out-of-plane distortion for their thin thickness. These distortions are usually straightened by thermal straightening such as flame heating method. After thermal straightening, the blocks are lifted and moved by cranes to assemble it at dry-dock stage. After this lifting process, out-of-plane deformation again happens frequently. And then, they continuously cause quality and accuracy problems in the final dry-dock process. So, it takes more time for repair and correction working. According to preceding research, the lifting process by cranes would offset the effect on thermal straightening. The target of this study is to develop a methodology analyzing the remaining efficiency of thermal straightening after block lifting. The development was based on the assumption of yield state at straightening region. Therefore the remaining efficiency was obtained by different stiffness slope while lifting & relieving. The efficiency formula was designed using inherent strain, and we made a table of zero-efficiency by cooling speed and class rule's steels. As a result, if the stress orthogonal to straightened line is calculated during lifting analysis by FEA, the efficiency can be obtained linearly to the values in the table. Finally, even optimized carling position can be designed by considering the regional data from series project and welding region on deck.

• Journal of the Society of Naval Architects of Korea
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• v.32 no.1
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• pp.9-16
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• 1995

The erection process planning is to decide erection strategy and sequence that satisfies dock duration. The erection scheduling is to decide erection date of each block. The load profile varies according to scheduling and it is related to building cost. It must be possible to simulate the various combinations of process plan and schedule for optimal planning. To develop the process planning system for optimal planning, the system that generate the sequence of erection automatically and the load leveling system are required. This paper suggests the method that generates the erection sequence. The load leveling should be done to all the ships in the same dock batch to get reliable results. In this case since the search space is very large, efficient optimization method is needed Our research achieved the load leveling system using Genetic Algorithm. This system made it possible to simulate various process plans to which schedule is considered.

• IE interfaces
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• v.24 no.1
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• pp.78-86
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• 2011

To mitigate space restriction and to raise productivity, some shipbuilding companies use floating-docks on the sea instead of dry-docks on the land. In that case, a floating-crane that can lift very heavy objects (up to 3,600 tons) is used to handle the blocks which are the basic units in shipbuilding processes, and so, very large blocks (these are called the mega-blocks) can be used to build a ship. But, because these mega-blocks can be made only in the area near the floating-dock and beside the sea, the space is very important resource for the process. Therefore, our problem is to make an efficient spatial schedule for the mega-block assembly yard. First of all, we formulate this situation into a mathematical model and find optimal solution for a small problem using a commercial optimization software. But, the software could not give optimal solutions for practical sized problems in a reasonable time, and so we propose a GA-based heuristic algorithm. Through a numerical experiment, finally, we show that the spatial scheduling algorithm can provide a very good performance.

• Journal of Navigation and Port Research
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• v.41 no.5
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• pp.329-336
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• 2017

This study suggests a general process of analyzing the mooring and cargo handling limit waves, which is an incident to the new energy port under long wave agitation. To reduce damages of ships and harbor structures due to strong wave responses, it is necessary to predict the change of wave field in the mooring berth to make the proper decision by dock master. The berthing area at a new LNG port in the east coast of Korea in this study is frequently affected by oscillations from waves of 8.5~13s periods in the wintertime. The long period waves give difficulties on port operation by lowering the annual berthing ratio. It needs to find the event waves from the real time offshore wave records, which cause over the mooring limits. For that purpose, the wave records from field measurement and offshore wave buoy were analyzed. From numerical simulation, the response characteristics of long period waves in the berthing area were deduced with or without breakwater expansion plan, analyzing the offshore field wave data collected for two years. Some event wave cases caused over the cargo handling and mooring limits as per the standard Korean port design guideline, and those were used for the decision of port operation by dock master, comparing with the real time offshore wave observations.

• Proceedings of the PSK Conference
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• 2002.10a
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• pp.314.2-314.2
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• 2002

DNA topoisomerases catalyze changes in DNA topology through cycles of transient DNA strand breakage and religation. During this process. the active site tyrosine in human DNA topoisomerase Ⅰ(Top Ⅰ) becomes covalently linked to the 3'-ends of a single-stranded nick in the DNA duplex, Stabilization of the Top Ⅰ-DNA cleavable complex is the common initial event leading to the cytotoxicity of top 1 inhibitors. (omitted)

• Journal of Korean Society of societal Security
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• v.1 no.1
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• pp.63-67
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• 2008

This study focuses on assessing the security ri sk or the terrorism in chemical process industries. This research modifies conventional method for assessing the terrorism risk. The risk assessment method is developed and it is implemented as software to analyze the possibility of terrorism and sabotage. This program includes five steps; asset characterization, threat assessment, vulnerability analysis, risk assessment and new countermeasures. It is a systematic, risk based approach in which risk is a function of the severity of consequences of an undesired event, the likelihood of adversary attack, and the likelihood of adversary success in causing the undesired event. The reliability of the program is verified using a dock zone case. The case dock zone includes a storage farm, a manufacturing plant, an electrical supply utility, a hydrotreater unit, many containers, and administration buildings. This study represents chemical terrorism response technology, the prevention plan, and new countermeasure to mitigate by using risk assessment methods in the chemical industry and public sector. This study suggests an effective approach to the chemical terrorism response management.

• Journal of the Korean Society of Manufacturing Process Engineers
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• v.11 no.1
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• pp.95-100
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• 2012

A deck crane is installed on the deck of a ship when there is no adequate facility for loading and unloading in dock or harbor. Deck cranes in Korea have been imported from abroad, and the import-substitution effect will arise if its production can be localized. Now, it is required to suggest the structural design of a deck crane that meet the domestic criterion, considering loading condition. In this study, the structural analysis of a pedestal in the deck crane was peformed by finite element method to investigate the strength requirement. In addition, the structural design of a pedestal was suggested by using ANSYS and VisualDOC. The optimized structure of a pedestal was determined, considering lightweight design.

• Journal of the Korean Society of Industry Convergence
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• v.26 no.6_3
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• pp.1305-1314
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• 2023

The global ship repair and modification market is expected to grow up to approximately $ 30 billion by 2025. Korea's shipbuilding industry is leading the world grounded on its international competitiveness in design and production technology. The reality, however, is that the ship repair and modification industry is centered on Gyeongnam, and there are only two to three ship repair workplaces that can repair large ships. Therefore, domestic ship repair companies target small and medium-sized ships mainly. This is because there are few workplaces equipped with a large dock in which large ships like LNG ships can be inspected regularly or repaired, complaints are severe for environmental problems, and related environmental regulations are so strict that it is very hard to obtain government approval for the extension of ship repair and modification workplaces or the opening of new shipbuilding sites. Besides, on account of the workers' high wages, few experts related, and higher ship repair price compared to that of Southeast Asia, most of the volume of repairing large ships including domestic LNG ships is being lost to Southeast Asian or Chinese markets. In this study, the work process and pre-work preparation process for ship hull (winch, windlass, hatch cover, ramp door, cargo gear, anchor chain) repair were analyzed and presented to foster domestic ship repair experts and revitalize related industries.

• Journal of the Korean Society of Marine Environment & Safety
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• v.28 no.7
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• pp.1267-1273
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• 2022

Although the Korea shipbuilding industry has recently been receiving most of the orders for ships in the world, production processes are being disrupted due to a shortage of manpower at the production site. This is because the workers quit the shipyard as both work and wages were reduced due to the long slump in the shipbuilding industry. The main reason for the increase in orders was the large-scale orders for Qatar LNG carriers, and the situation in which the technical specifications required for ships are becoming more complex is also working to an advantage. Because the contract delivery time is of utmost importance for ships, the dock launch plan is the most important management item among the shipyard's major processes. The structure to be built in the dock may be a hull that has left the design work or a finished vessel, and in some cases, it is often at the level of some blocks of the hull. When launching, the hull is affected by the hogging or sagging moment due to the fluid force, and securing the safety of the structural strength of the block connection is of utmost importance. In a normal process, the connecting member launches after welding has been completed, but in actual shipbuilders, quick decision-making is needed on the conditions for securing structural safety to comply with the docking schedule. In this study, a detailed analysis method and applicability using a bending stress evaluation method and finite element analysis modelling were analyzed to rationally judge the above-mentioned problems from an engineering point of view. The main contents mentioned in the thesis can be used as good examples when conducting similar structural strength evaluations in the future.