• Clinical and Experimental Pediatrics
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• 제55권10호
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• pp.371-376
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• 2012

Purpose: Puromycin aminonucleoside (PAN) specifically injures podocytes, leading to foot process effacement, actin cytoskeleton disorganization, and abnormal distribution of slit diaphragm proteins. p130Cas is a docking protein connecting F-actin fibers to the glomerular basement membrane (GBM) and adapter proteins in glomerular epithelial cells (GEpCs; podocytes). We investigated the changes in the p130Cas expression level in the PAN-induced pathological changes of podocytes in vitro. Methods: We observed changes in the p130Cas expression in cultured rat GEpCs and mouse podocytes treated with various concentrations of PAN and antioxidants, including probucol, epigallocatechin gallate (EGCG), and vitamin C. The changes in the p130Cas expression level were analyzed using confocal immunofluorescence imaging, Western blotting, and polymerase chain reaction. Results: In the immunofluorescence study, p130Cas showed a diffuse cytoplasmic distribution with accumulation at distinct sites visible as short stripes and colocalized with P-cadherin. The fluorescences of the p130Cas protein were internalized and became granular by PAN administration in a dose-dependent manner, which had been restored by antioxidants, EGCG and vitamin C. PAN also decreased the protein and mRNA expression levels of p130Cas at high doses and in a longer exposed duration, which had been also reversed by antioxidants. Conclusion: These findings suggest that PAN modulates the quantitative and distributional changes of podocyte p130Cas through oxidative stress resulting in podocyte dysfunction.

• 유통과학연구
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• 제8권4호
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• pp.25-34
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• 2010

While jujubes are mainly sold in dried forms as wholesome foods, sacrificial food and so on, processed foods from jujube are neither highly recognized nor in high demand. Hence, this study has proposed ways to enhance the demand for jujube processed foods and will help prepare the ground for efficient marketing strategies, based on the survey result on the pattern in which customers in Korea purchase jujube-processed foods. The conclusion for this study has been derived by researching the relevant literature and analyzing the relevant company data and customer survey results. The study implies the following points regarding enhancing the demand for jujube-processed foods. First, long-term solutions are necessary. These may include establishing a technological system that can produce various foods processed from jujubes, and improving the customer accessibility in accordance with the changes in the retail environment. To implement these solutions, it is necessary to familiarize the customers with jujube-processed foods by securing a good sales network and through active promotion and advertising. Second, systematic marketing strategies are needed, which may be applied in developing the products as well as distribution and promotion methods and prices that correspond with the changes in the customer environment and the different tastes for various age, gender and residential area groups.

• Proceedings of the National Institute of Ecology of the Republic of Korea
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• 제4권4호
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• pp.141-145
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• 2023

This study surveyed the changes in the proportion of Ecological and Natural Map (ENM) grades in Korea, the distribution ratio of ENM 1st-grade areas by region, and the current status of regional public appeals for the five-year period from 2017 to 2021. The nationwide changes in ENM grades revealed an increase in 1st-grade, 3rd-grade, and separately managed areas but a decrease in the ratio of 2nd-grade areas. Nationwide, Gangwon had the highest distribution ratio of 1st-grade areas, at 46.77%, while Gwangju had the lowest, at 0.05%. In the five-year study period, 383 appeals concerning ENM grades were received and processed. Gangwon had the greatest number of appeals, with 96, while Sejong had the fewest, with 1. A significant correlation was observed between the distribution ratio of 1st-grade areas and public appeals.

• Ocean Systems Engineering
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• 제12권4호
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• pp.403-411
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• 2022

Annually, about 48-60% of sediment discharge of the Mekong River is delivered near the mouths of the Mekong River branches which is mostly coinciding with the southwest (SW) monsoon. This sediment budget in turn will be southwestwardly transported along the coast of the Mekong Delta (MD) during the northeast (NE) monsoon. Analysis of monsoonal changes in grain-size distribution (GSD) of surface sediment contributes to a better understanding of erosion and deposition processes along the MD. This study aims to figure out changes in GSD and sediment textures along the MD between SW and NE monsoons based on 183 surficial sediment samples collected along the MD during two field surveys carried-out in October 2016 and February-March 2017. Compared to the GSD during the SW and NE monsoon, the GSD along the MD changed significantly, especially in the estuary areas and along the coast of Bac Lieu and Ganh Hao. Whereas, in the west coast of the MD, GSD seem no changes between the two seasons. These changes in seabed sediment suggest that sediment with grain-sizes ranging from silt to fine sand can be transported during only a NE season.

• 환경영향평가
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• 제15권1호
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• pp.67-78
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• 2006

Global warming brings about changes of diverse environmental, especially changes of plant distribution. The purpose of this paper is to examine the relationship between temperature rise and changes of northern limit of vegetation growth in Korea. Bamboos (Phyllostachys) and boundary between the northern type and southern type of garlic (Allium sativum L.) were selected. The data of the distributions of bamboos and garlic are collected by field survey and interviews. Temperature is analyzed from 1904 to 2000. The northern limit of Phyllostachys moves 60-100 km northward, for about 100 years, the period of 1907-2003 and mean temperature of Korea increases about $2^{\circ}C$ during the same period. It means that the northern limit moves 30-50 km northward, for each $1^{\circ}C$ rising of January mean temperature. The boundary between the northern type and southern types of garlic moves northward 40-140 km from 1980s to 2000. The moving width is broad in the west coastal region while the width is narrow in the inland and mountain regions. The mean moving width is about 100 km.

• 보건행정학회지
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• 제14권3호
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• pp.20-44
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• 2004

The National Health Insurance Expenditure has been increased rapidly since the introduction of the separation of prescription and dispensing in 2000, and this trend of rapid growth in overall spendings rate has been observed predominantly among medical practitioners. This study was conducted to investigate the growth rate and distributional changes in private medical practitioners' expenses from 1999 to 2002 and its determinants using the National Health Insurance claims data. The total increasing rate of all medical practitioners' expenditure paid by the National Health Insurance between 1999 and 2002 was $41.71\%$, which exceeding that of general hospitals by $20\%$p. But the income distribution among each practitioner was improved as the changes in Gini coefficient(from 0.40 to 0.38) and decile distribution ratio(from 0.25 to 0.29) during the same period showed. However, this improvement in distributional patterns is not enough since even in 2002 it turned out that the highest $10\%$ income group earned 33times more than the lowest $10\%$ income group did. Also, higher Gini coefficient was observed in larger cities and some department like plastic surgery, obstetrics and gynecology. The major causes of this differentials in medical practitioners' expenses were factors related to medical demand like proportion of old population, residential economic status in a given area. In addition, providers' economic incentives also played an important role in determining their income distribution. The large income differentials among physicians may imply a skewed distribution of patients and thus long waiting time, inefficient utilization of resources and potential inadequate quality of care. In this sense, unreasonable distributional gaps should be reduced, so effective measures as well as ongoing monitoring would be necessary to correct current distributional problems.

• 산경연구논집
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• 제11권5호
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• pp.27-34
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• 2020

Purpose: North Korea is a very close country geographically and culturally, but the nation has been one of the most secretive countries in the world. However, in recent years, North Korean society has been known to rapidly change its economic environment as well as its diplomatic and political environment. Since the gaining power of Jong-un, Kim in 2012, the North Korean government has implemented a new set of economic policies. North Korea has embraced limited market systems and mechanisms that have become a part of the formal planned economy. This study is concerned with the recent changes in the market and marketing activities of the communist country. It also seeks to gain an understanding of the changing market behavior of North Korean consumers. The purpose of this study is to enhance understanding of the market environments of North Korea and to provide appropriate implications for practitioners and researchers. Research design, data and methodology: Academic access to information that can understand North Korea's reality is minimal. Therefore, this study was conducted based on a qualitative analysis of secondary data. The existing literature on North Korea, related news and reports were the basis of the analysis. Analysis of secondary data related to North Korea was the main methodology of the study. Results: The official ideology of North Korea rejected most aspects of marketing, and yet there were marketing activities in North Korea. This article focuses on the development of market and marketing activities in North Korea during the recent years. This study indirectly confirmed that the market function is being activated in North Korea, and the basic functions of marketing such as advertisement, price, and distribution are being formed. In this process, the activation of the 'Jangmadang(market)' played a significant role. Conclusions: Research shows that North Korea is rapidly developing its own market function. In addition, marketing activities such as advertising and pricing strategies seem to be unprecedentedly active. However, due to changes in the political environment, the future development of North Korea's marketing is still in flux. Efforts to improve mutual understanding through continuous research are required.

• 패션비즈니스
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• 제11권6호
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• pp.115-124
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• 2007

The cross-section of the polyester filament yarn has been modified to have a variety of shape for aesthetic, added functions and sensitivities, and other purposes. Transparent polyester filament of trilobal cross-section has unique optical properties with high anisotropic reflectivity and transmissivity. The monofilament yarns may be utilized to impart to the fabrics lustrous appearance along with unique color change in case differently dyed yarns are woven together. The color changes of the fabric specimens according to the changes in observation and lighting conditions were analyzed using a CCD camera and an image analysis software. The changes of color/luster of the fabric specimens were measured and analyzed based on RGB, $L^*a^*b^*,\;L^*C^*h,$ and the color distribution within a three-dimensional color space.

• 한국해안·해양공학회논문집
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• 제28권3호
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• pp.171-176
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• 2016

기온과 수온의 분포형태는 발생빈도의 양상을 결정하는 기본적이고 필수적인 정보이다. 또한 기후변화에 의한 기온과 수온의 장기변화 양상 파악에 유용하다. 기온과 수온의 전형적인 분포형태는 다수의 첨두(mode)를 가지는 형태로 일반적으로 널리 사용되는 정규분포로 표현하기에는 한계가 있다. 본 연구에서는 Gaussian 혼합함수와 Kernel 분포함수를 보다 기온과 수온의 보다 적합한 분포함수 형태로 제안한다. 제안된 분포함수를 우리나라 연안 기온과 수온자료를 이용하여 추정-평가한 결과, 관측 자료의 분포는 꼬리 영역에서 크게 차이를 보이고 있는 것으로 파악되었다. 높은 수온영역과 낮은 기온 영역에서 꼬리 영역이 길게 나타나고 있다. 또한 본 연구에서 제안한 분포함수 추정 및 비교는 기온과 수온의 상호 변동관계 및 장기적인 변동양상을 파악할 수 있다. 그러나 평균 기온 및 수온 그리고 정규분포 함수 형태로는 이러한 변화 양상의 파악은 크게 제한되고 있다.

• 한국환경과학회:학술대회논문집
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• 한국환경과학회 2000년도 정기총회 및 봄 학술발표회
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• pp.251-254
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• 2000

In this study, we investigated vertical distribution and seasonal changes of phytophlankton community in the Hae-Dong Reservoir from March 1999 to Feburary 2000. This reservoir is relativly small (surface area, 2.7 $km^2$) and is the source of drinking water supply to the eastern part of Pusan City. Samples were collected at 2 sites (1, 3, and 6 m; site 1, in front of the dam; site 2, inlet). The dominant group was Bacillriophyceae at both sites (over 63%), and other groups exhibited seasonal changes (high cyanobacterial density in summer; green algal communities in winter). Chrysophyceae and Dinophyceae were maintained lower level during the study period. Along the water depth, all classess of phytoplankton did not show distintive vertical distribution at both sites except during the blue-green algal bloom in the middle of July and late September. The phytoplankton community dynamics in the Hoe-Dong Reservoir was strongly affected by the hydrological factors such as concentrated precipitation and short retention time.