• Journal of Communications and Networks
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• v.16 no.5
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• pp.534-547
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• 2014

Large-scale failures resulting from natural disasters or intentional attacks are now causing serious concerns for communication network infrastructure, as the impact of large-scale network connection disruptions may cause significant costs for service providers and subscribers. In this paper, we propose a new framework for the analysis and prevention of network service disruptions in large-scale failure scenarios. We build dynamic deterministic and probabilistic models to capture the impact of regional failures as they evolve with time. A probabilistic failure model is proposed based on wave energy behaviour. Then, we develop a novel approach for preventive protection of the network in such probabilistic large-scale failure scenarios. We show that our method significantly improves uninterrupted delivery of data in the network and reduces service disruption times in large-scale regional failure scenarios.

• Journal of Integrative Natural Science
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• v.5 no.3
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• pp.198-210
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• 2012

Circadian rhythms govern a remarkable variety of metabolic and physiological functions. Accumulating epidemiological and genetic evidence indicates that the disruption of circadian rhythms might be directly linked to cancer. Intriguingly, several molecular gears constituting the clock machinery have been found to establish functional interplays with regulators of the cell cycle, and alterations in clock function could lead to aberrant cellular proliferation. In addition, connections between the circadian clock and cellular metabolism have been identified that are regulated by chromatin remodelling. This suggests that abnormal metabolism in cancer could also be a consequence of a disrupted circadian clock. Therefore, a comprehensive understanding of the molecular links that connect the circadian clock to the cell cycle and metabolism could provide therapeutic benefit against certain human neoplasias.

• The Bulletin of The Korean Astronomical Society
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• v.43 no.1
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• pp.31.1-31.1
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• 2018

While astronomers are working hard to detect the earliest galaxies and to follow their evolution to redshift z~0, they remain baffled by the present-day dichotomy between disky, star forming (aka late-type) galaxies and quiescent, spheroidal (aka early-type) galaxies. The key is to find galaxies in transition from one class to the other, whose spectra indicate intense recent star formation that has now ended. We have identified thousands of such "post-starburst galaxies" and discovered that they are often the products of late-type galaxy-galaxy mergers. Their current kinematics, stellar populations, and morphologies are consistent with late- to early-type galaxy evolution. I will discuss recent work that suggests new connections between this violent history and the central supermassive black hole. In particular, the molecular gas reservoir of a post-starburst galaxy declines rapidly after the starburst ends and in a manner consistent with feedback from an active nucleus. Furthermore, a star is ~300x more likely to be tidally disrupted by the nucleus of a post-starburst galaxy than in other galaxies. Like the well-known black hole-bulge mass correlation, these surprising links between the properties of a galaxy on kpc scales and its supermassive black hole on pc scales require explanation.

• The Plant Pathology Journal
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• v.28 no.4
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• pp.401-408
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• 2012

Initial subcellular responses in susceptible (PI 274420) and resistant (cv. Hartwig) soybeans infected with the soybean cyst nematode (SCN) were examined 2 and 4 days after inoculation (DAI). Subcellular features common to both soybeans at 2 DAI included hypertrophied initial syncytial cells (ISCs) and syncytium-component cells (SCs) with a dense cytoplasm containing proliferated rough and smooth endoplasmic reticulum (RER and SER), a hypertrophied nucleolus, and reduced vacuoles, suggesting that the nematode-infected cells were dedifferentiated. In the resistant soybean, a striking initial subcellular difference from the susceptible soybean was the dilation of the RER, indicating ER dysfunction and leading to cell death. This disturbed nematode feeding, as evidenced by disrupted feeding tubes. In PI 274420, the ISC cytoplasm was depleted, with the exception of ER membranes, at 4 DAI, while the SC cytoplasm was dense with proliferation of starch-containing plastids around multiple nuclei that might be derived from the congregation of nuclei in the neighboring SCs and in part by nuclear division without cytokinesis. In cv. Hartwig, syncytia were necrotized with secondary cell wall thickening outside the plasma membrane and an extremely dense cytoplasm containing a nucleus with an electron-lucent nucleolus, accompanied by the proliferation of closely stacked parallel RER and ribosomes. These results suggest that syncytia develop continuously in PI 274420 to produce and store nutritional substances in SCs, providing for the nematode through ISC until maturation, but in cv. Hartwig, syncytia degenerate early due to excessive metabolism, blocking nematode feeding and cytoplasmic connections with adjacent intact cells.

• The KIPS Transactions:PartC
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• v.11C no.7 s.96
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• pp.889-894
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• 2004

Most ad-hoc routing protocols such as AODV(Ad Hoc On-Demand Distance Vector) and DSR(Dynamic Source Routing) do not try to search for new routes if the network topology does not change. Hence, with low node mobility, traffic may be concentrated on several nodes, which results in long end-to-end delay due to congestion at the nodes. Furthermore, since some specific nodes are continuously used for long duration, their battery power may be rapidly exhausted. Expiration of nodes causes connections traversing the nodes to be disrupted and makes many routing requests be generated at the same time. Therefore, we propose a load balancing approach called Simple Load-balancing Approach (SLA), which resolves the traffic concentration problem by allowing each node to drop RREQ (Route Request Packet) or to give up packet forwarding depending on its own traffic load. Meanwhile, mobile nodes nay deliberately give up forwarding packets to save their own energy. To make nodes volunteer in packet forwarding. we also suggest a payment scheme called Protocol-Independent Fairness Algorithm (PIEA) for packet forwarding. To evaluate the performance of SLA, we compare two cases where AODV employs SLA or not. Simulation results show that SLA can distribute traffic load well and improve performance of entire ad-hoc networks.