• 대한예방한의학회지
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• 제12권1호
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• pp.149-156
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• 2008

In the situation providing the aged society, the contents of the symptoms of senility centering around the aged-pulse condition were arranged. The results were as follows. In the questions about the aged symptoms, the results of indicating the gradual physical-age following the aged symptoms with the real age(from 40 to 100, 7 grade) and the gradual physical-age following the ageing grade of male and female (the 3 grade of the female / the 4 grade of the male) could have the differentiations. And the distinction of the aged pulse condition was observed two pulse condition ; the one is the minute pulse condition(Mi, Sei ;微細) as lowering function and the other is the Hyun, Ghin(弦, 緊) pulse condition as the blood's tention and contration.

• 대한약침학회지
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• 제17권3호
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• pp.57-61
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• 2014

Objectives: When a person speaks, voice problems usually include pain or discomfort and/or difficulties in terms of the pitch, the loudness and the quality of the voice. When patients with voice problems induced by stroke, Parkinson's disease, and systemic diseases involving the voice are examined, generally, of the Four Diagnoses (四診), a Diagnosis of Hearing can be used in current Korean medicine. The effects of acupuncture and herb medicine on voice problems have been reported for over 20 years. However, when it comes to improvements, objective and subjective evaluation methods need to be explained. Methods: Subjective methods for evaluating voice were studied through a literature search of old medicinal books containing Korean medicine diagnostics, and an objective evaluation method using Praat software is presented. Results: Korean medicine doctors analyze the patient's voice in clinical settings unconsciously on a daily basis. However, most voice diagnoses depend on the doctor's subjective evaluation. Voice qualities can be evaluated by using the Eight Principles (八綱), including Yin-Yang; the Five Elements (Phases); the Grade, Roughness, Breathy, Asthenic, Strained (GRBAS) score, and the Visual Analogue Scale (VAS) as subjective methods, and an acoustic analysis using the Praat program can be used as an objective method. Conclusion: A more complete voice examination can be achieved by using subjective and objective methods at the same time. For an objective explanation and management of patient's voice problems or systemic disorders, an objective method should be used in Korean medicine, which already has many subjective diagnostic methods. More research needs to be conducted, and more clinical evidence needs to be collected in the future.

• 대한의생명과학회지
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• 제26권3호
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• pp.127-135
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• 2020

Coronavirus is generally known to cause minor respiratory diseases in animals and humans. However, some coronavirus genus is reported to cause animal-to-human interspecies infection. Since the end of 2019, a new type of coronavirus (COVID-19) infection is spreading rapidly throughout the world, leading to the declaration of the pandemic by the World Health Organization (WHO). Despite various clinical studies to counter COVID-19 infection, the total confirmed cases and death rates are still accumulating. To break down this new threat, we should pay attention to newly revealed information based on scientific facts. In this review, we introduced the clinical characteristics, diagnostic methods, and treatment of patients infected with COVID-19. Moreover, we highlighted the correlation between COVID-19 severity and patients with underlying diseases. Potential risks associated with COVID-19 can be differed depending on the condition of patients and can cause pulmonary complications. Therefore, lung capacity exams are expected to help predict the progression of the disease along with previously established detection methods such as molecular diagnostics and immunoassay. Although physiological research hasn't yet been emphasized to evaluate COVID-19 infection, this review is expected to be valuable to give new inspiration to deal with COVID-19 which might strike again in the future.

• 제3의학
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• 제1권1호
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• pp.37-44
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• 1996

This study has surveyed the problems raised through the standardization process of differentiation system and searched its solution, reaching the following conclusion. 1. The most serious problem is, most frequently occurred, an wilful application of differentiation system or constitutive classification for disease. 2. To overcome this wilfulness, we must make a definite understanding of the origin and its applicative limit of the theory. 3. And it must be preceded for a correct and objective differentiation to standardize in all choice of the differential diagnostics and its applicative condition. 4. To establish such a corresponding diagnostic scheme, it must be generally agreed on an individuality and inevitability of the suitability to differentiation principles. 5. And, though we can make a prescription through the frequency, degree, and clarified cause of the symptom, its flexibility of application must not be necessarily, ignored. 6. As this study for standardizing the disharmony between liver and pancreas(肝脾不調) shows, accordingly, we must begin by scrutinizing and defining what the chief cause, head, and inevitable symtoms are and discern them from its affinities, making necessarily a great deal attention to minute feelings and degree about its individual symptoms. On the ground of these recognition, we must go further to establish a general standardization and try to get a specific study series.

• 대한한의학회지
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• 제17권2호
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• pp.58-72
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• 1996

I. PURPOSE AND SIGNIFICANCE OF RESEARCH The presentation of research direction for compositive study and application of oriental medicine is urgently demanded. Since there is few investigation for the interest in basic and clinical field of oriental medicine, and we hope that compositive study and concentrative research between instruction in college and local clinics is established by this research. II. RESEARCH CONTENT ${\cdot}$ Analysis of survey in basic field of oriental medicine as instruction curriculum. ${\cdot}$ Analysis of survey in clinical field of oriental medicine as the classification of disease. III. RESULT The result of investigation shows that the most interested field is acupuncture and moxibustion in clinical field and diagnostics in basic field of oriental medicine. And oriental medicinal clinic doctors are concerned about prescription and a newly-developed techniques such as new acupuncture therapy, new machines. They hope that a study of oriental medicine in clinical field be accomplished with the special clinics as leader. According to the previous results, we can work out the foundation of compositive study and concentrative research between instruction in college and local clinics, and on this ground it is considered that we can grope for the presentation of research direction of local clinics.

• 대한한의학원전학회지
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• 제28권1호
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• pp.21-34
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• 2015

Objectives : The treatment starts with physical examination. The four examinations(四診) is a method to examine the disease. The books on history of diagnostics about it contained substantial contents about inspection(望診) and palpation including pulse taking(切診), while they contained little contents about auscultation(聞診) and interrogation or questioning(問診) relatively. For this reason, this study was conducted as on interrogation first of all. Methods : I looked into the contents related to interrogation that were scattered in plenty of books. There were chapters of specialty in interrogation since the Ming dynasty, so I looked into these chapters in chronological order. Results & Conclusions : The level of the contents of interrogation prior to the Ming dynasty were rudimentary and recapitulative. However, there was a turning point by three kinds of books appeared in the Ming dynasty. Yixuerumen Wenzheng dealt with detailed contents. Yixuezhunshengliuyao Wenbingbixiang extended the range of contents. Jingyuequanshu Shiwenpian systematized Eight Principle Pattern Identification(八綱辨證) with increase of contents. Since then, books of the Qing Dynasty were mostly based on three kinds of books ahead. Among these, Yimenfalu Yimingwenbingzhifa(醫門法律 一明問病之法) and Xingsewaizhenjianma wenfa(形色外診簡摩 問法) mentioned the importance of a succinct interrogation that hit the mark and Yibian Yiwenzheng dealt with another detailed contents unlike the previous books based on substantial contents.

• 스마트미디어저널
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• 제2권4호
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• pp.34-40
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• 2013

다양하고 빠른 차세대 유전체 서열 분석기를 사용한 개인 유전체 분석은 생명과학 연구뿐만 아니라 질병의 진단과 치료를 포함하는 의학 분야까지 새로운 지평을 열고 있다. 저렴한 비용으로 읽혀진 개인 유전체 서열은 통합 과정을 거쳐 유전체 이상을 점검할 수 있고, 얻어진 서열 데이터는 유전자 변이성 연구, 유전체 발현 연구, 후성유전학적 연구, 유전체 주석화 등에 이용될 수 있다. 개인 유전체 데이터는 생물학적 연구 결과와 임상 연구 데이터를 연계하여 질환 위험도의 예측과 맞춤 치료에 이용할 수 있게 되었다. 개인 맞춤의학 시대에 전문적 데이터와 일반인 사용자의 간극을 메우기 위해 스마트 미디어 기기와 같은 적극적인 인터페이스의 개발이 시급하다.

• Korean Journal of Acupuncture
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• 제26권3호
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• pp.103-110
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• 2009

Objectives : The purpose of this study is to review the Seven Acupoints for Stroke and reveal the meaning of the composition of that. Methods : 1. The authors reviewed several literatures and studies related with the Seven Acupoints for Stroke. 2. We investigated the composition of Seven Acupoints for Stroke and found the mechanism of the function and clinical usefulness of that. Results and Conclusions : 1. Seven Acupoints for Stroke is composed of 7 acupoints, i.e. 1 acupoint of Governer Vessel, 2 acupoints of Yang Myoung meridian, and 4 acupoints of So Yang meridian construct that. 3. Seven Acupoints for Stroke can be used for many of central nervous disease related with stress.

• 대한임상검사과학회지
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• 제38권3호
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• pp.158-165
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• 2006

Although Mycobacterium tuberculosis complex strains remain responsible for the majority of diseases caused by mycobacterial infections worldwide, the increase in HIV infections has allowed for the emergence of other non-tuberculous mycobacteria as clinically significant pathogens. However, Mycobacterium species has a long period of incubation, and requires serious biochemical tests such as niacin, catalase, and nitrate test that are often tedious. The development of rapid and accurate diagnostics can aid in the early diagnosis of disease caused by Mycobacterium. The current DNA amplification and hybridization methods that have been developed target several genes for the detection of mycobacterial species such as hps65, 16S rDNA, rpoB, and dnaj. These methods produce rapid and accurate results. In this study, PCR-restriction fragment length polymorphism analysis(PCR-RFLP) based on the region of the rpoB gene was used to verify the identification of non-tuburculosis Mycobacterium species. A total of 8 mycobacterial reference strains and 13 clinical isolates were digested with restriction enzymes such as Msp I in this study. The results of using this process clearly demonstrated that all 13 specimens were identified by rpoB gene PRA method. The PCR-RFLP method based on the rpoB gene is a simple, rapid, and accurate test for the identification of Mycobacterium.

• 동의생리병리학회지
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• 제20권4호
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• pp.759-765
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• 2006

In order to provide the methodology of researching constitutional theories, the original meaning and the source of the term, ti(體) and zhi(質) written in and other text were reviewed, and then components of constitution(體質) and some evaluative norms and prospect on constitutional theories were proposed. Ti(體) means body or 5 tissues or patterns of them and zhi(質) means quality in , so the temporary meaning of constitution was generally same with present one. But the temperament originated from Greek and Elizabethan era is thought that it corresponds with constitution, but it means generally body type and character and mental pathologic features. The fundamental requirements of constitutional theories are needed stability, creativity, clinical efficiency and reproductiveness for differentiating with classical diagnostics over the range of disease and aging of the subject. And heredity, universality and extensiveness were recommended as additional requirements for making level up the theories through long-term follow-up, and to evaluate these requirements detail items were proposed. More of these, weight rendering should be made respectively afterwards.