• Title/Summary/Keyword: Disease burden

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Deciding not to Operate in Head Injuries and Legal Considerations

  • Choi, Il;Lee, Kyeong-Seok;Shim, Jai-Joon;Choi, Weon-Rim
    • Journal of Korean Neurosurgical Society
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    • v.42 no.2
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    • pp.135-140
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    • 2007
  • It is not the best way to treat a hopeless patient with life-sustaining medical devices until the heart beats stop. Advanced medical technology may prolong the life for a significant period without recovery from the disease. However, it would give an unbearable economic burden to the family and the society. In 2006, we decided not to operate 9 patients with traumatic intracranial hematomas. We examined those patients with special references to possible legal and ethical problems. It is reasonable to withhold a treatment after documentation that the family never wants any life sustaining treatment when the treatment does not guarantee the meaningful life.

Update in varicella vaccination (수두백신의 최신지견)

  • Oh, Sung Hee
    • Clinical and Experimental Pediatrics
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    • v.49 no.3
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    • pp.229-234
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    • 2006
  • Varicella, which is mostly a benign disease, but also can cause considerable health burden in the community, can be prevented by immunization with live attenuated varicella vaccine. Higher uptake of varicella vaccine by universal immunization in North America has apparently been associated with decline in the number of reported cases of varicella, varicella-related hospitalizations, and the number of deaths caused by complications of varicella. On the contrary, there has been some reluctance in endorsing varicella vaccine for universal immunization in most of European countries. Concerns include unanticipated outbreaks of varicella among vaccine recipients, risk of varicella among unvaccinated adults, risk of herpes zoster among vaccinees as well as unvaccinees. Recently developed measles, mumps, rubella, and varicella combination vaccine and herpes zoster vaccine that may be licensed in the upcoming years may be the solution for varicella vaccine to be utilized in a greater scale. In Korea several varicella vaccine products have been utilized since late 1980. The adoption of varicella vaccine for universal immunization since 2005 along with the changing view in varicella prevention strategy mandates more studies for immunogenecity and efficacy of varicella vaccines as well as more surveillance to delineate the changes in epidemiology of varicella in Korea.

Comparative Analysis of Maximum Vertical Reaction Force and Lower Limbs on Drop Landing between Normal and Flat Foot Group

  • Yoo, Kyung-Tae
    • Journal of International Academy of Physical Therapy Research
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    • v.2 no.1
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    • pp.222-228
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    • 2011
  • With comparison of maximum vertical reaction force and lower limb on drop landing between normal and flat foot group, this study is to provide fundamental data of the prevention of injury and the treatment of exercise which are frequently occurred on flat foot group's drop landing. The surface electrodes were sticked on lateral gastrocnemius muscle, medial gastrocnemius muscle, tibialis anterior and the drop landing on a force plate of 40cm was performed with a normal group who had no musculoskeletal disease and a flat foot group of 9 people who had feet examinations. Vertical reaction force were significantly statistically different between two groups(p<.001). Muscle activity of lower limbs in all three parts were not statistically different but showed high tendency on average in the flat foot group. The flat foot group had difficulties in diversification of impact burden and high muscle activity. Therefore, it was suggested that muscular strengthening of knee joints and plantar flexions of foot joints which were highly affected in impact absorption will be required.

Overview of Cancer Registration Research in the Asian Pacific from 2008-2013

  • Moore, Malcolm A.
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.8
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    • pp.4461-4484
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    • 2013
  • Cancer registration provides a firm basis for cancer control efforts and research into changing patterns of incidence, mortality, survival and prevalence is of obvious importance. Most of the countries of Asia have already published relevant data although the level of coverage and accuracy do vary a great deal both between and within countries. The present review concerns the relevant literature for the period 2008-2013, focusing on the types of research conducted and the conclusions that can be drawn with regard to what should be done in the future to translate the information available into effective intervention efforts to reduce the burden of disease. A major emphasis has been on determining variation in incidence and mortality/survival on the basis of ethnicity and socioeconomic as well as geographical background, as well as trends over time, either for cancer in general or specific organ sites. In addition a small number of papers focused on methodological, quality and cancer control issues, very pertinent to the future development of cancer registry based research.

Overview of management of children with COVID-19

  • Wati, Dyah Kanya;Manggala, Arya Krisna
    • Clinical and Experimental Pediatrics
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    • v.63 no.9
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    • pp.345-354
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    • 2020
  • The widespread and contagious coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 has become a burden in the global health domain. The subsequent discovery of the virus features and pathogenesis, and prompt and adequate management are still lacking and remain inconclusive. Children usually present milder symptoms than adults, and management focuses on providing symptomatic and respiratory supports. Several treatment modalities, including the utilization of mechanical ventilation (MV), antivirals, immune-modulating drugs, or other agents, may present promising results in reducing the symptoms of COVID-19, particularly in severe cases. Although no randomized clinical trials have been published to date, it is interesting to explore potential modalities for treating COVID-19 in children, based on review articles, case reports, and recent guidelines.

Sick or sickness? The importance of person centred healthcare and medicine paradigm

  • Tassinari, Mariateresa;Roberti di Sarsina, Paolo
    • CELLMED
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    • v.4 no.4
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    • pp.24.1-24.4
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    • 2014
  • When you act for a good or just when you make a choice, you should ask yourself if the result of your action coincides with the principle that has generated it. Health and respect for our own individuality are two essential goods for the human being and also values that medicine itself should guard carefully remembering that its goal is to take care for a person and not only to cure a sick body. The means to achieve all this can only be a person-centered medicine which has the honor and the burden of considering the person (in the Kantian sense) and his health as an end, not a means. The current mainstream concept of health defined in 1948 by the World Health Organization as a state of complete mental, physical and social wellbeing and not merely the absence of disease and infirmity remind us that medical reasoning, based on the pathogenesis operator, is no longer sufficient in dealing with requests from the citizens: is now the right time to shift the focus from sickness to health giving emphasis to the salutogenic medicine approach.

WHO Treatment Guidelines for Drug-Resistant Tuberculosis, 2016 Update: Applicability in South Korea

  • Jeon, Doosoo
    • Tuberculosis and Respiratory Diseases
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    • v.80 no.4
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    • pp.336-343
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    • 2017
  • Despite progress made in tuberculosis control worldwide, the disease burden and treatment outcome of multidrug-resistant tuberculosis (MDR-TB) patients have remained virtually unchanged. In 2016, the World Health Organization released new guidelines for the management of MDR-TB. The guidelines are intended to improve detection rate and treatment outcome for MDR-TB through novel, rapid molecular testing and shorter treatment regimens. Key changes include the introduction of a new, shorter MDR-TB treatment regimen, a new classification of medicines and updated recommendations for the conventional MDR-TB regimen. This paper will review these key changes and discuss the potential issues with regard to the implementation of these guidelines in South Korea.

Disease Burden and Etiologic Distribution of Community-Acquired Pneumonia in Adults: Evolving Epidemiology in the Era of Pneumococcal Conjugate Vaccines

  • Heo, Jung Yeon;Song, Joon Young
    • Infection and chemotherapy
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    • v.50 no.4
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    • pp.287-300
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    • 2018
  • Pneumonia is the leading cause of morbidity and mortality, particularly in old adults. The incidence and etiologic distribution of community-acquired pneumonia is variable both geographically and temporally, and epidemiology might evolve with the change of population characteristics and vaccine uptake rates. With the increasing prevalence of chronic medical conditions, a wide spectrum of healthcare-associated pneumonia could also affect the epidemiology of community-acquired pneumonia. Here, we provide an overview of the epidemiological changes associated with community-acquired pneumonia over the decades since pneumococcal conjugate vaccine introduction.

Single-Stage Open Repair of Extensive Arch and Descending Thoracic Aneurysm through Sternotomy: A Case Report

  • Kim, Joon Young;Kim, Hong Rae;Kim, Joon Bum
    • Journal of Chest Surgery
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    • v.54 no.6
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    • pp.509-512
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    • 2021
  • Extensive thoracic aortic disease involving the ascending aorta, the aortic arch, and the descending thoracic aorta may require multiple surgical and interventional managements, which impose a burden in terms of cumulative surgical trauma and the risk of interval mortality. Herein, we describe a single-stage arch and descending thoracic aorta replacement via sternotomy in a patient with multiple comorbidities presenting with an extensive thoracic aortic aneurysm.

Supporting Patients With Schizophrenia in the Era of COVID-19 (COVID-19 유행 시기의 조현병 환자 지원)

  • Kim, Sung-Wan
    • Korean Journal of Schizophrenia Research
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    • v.24 no.2
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    • pp.45-51
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    • 2021
  • The coronavirus disease 2019 (COVID-19) pandemic has drastically impacted our society and health care system. People with schizophrenia are more vulnerable to this burden of illness and related societal changes. In addition, they are more susceptible to the transmission of COVID-19 and have a significantly higher mortality rate compared to the general population. In a recent study, vaccinated patients with schizophrenia showed a greatly decreased mortality level similar to that of the general population. However, patients with schizophrenia were less likely to be vaccinated. Mental health professionals should provide them with appropriate information on prevention strategies against COVID-19 and vaccination. Long-lasting social distancing and social disconnection can make people with schizophrenia more vulnerable to loneliness and depression. Furthermore, patients with schizophrenia may face challenges continuing psychiatric treatment due to the COVID-19 pandemic. Social support and suitable mental health services using novel technologies should be developed and provided to patients with schizophrenia.