• Title/Summary/Keyword: Discovered

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Finding associations between genes by time-series microarray sequential patterns analysis

  • Nam, Ho-Jung;Lee, Do-Heon
    • Proceedings of the Korean Society for Bioinformatics Conference
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    • 2005.09a
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    • pp.161-164
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    • 2005
  • Data mining techniques can be applied to identify patterns of interest in the gene expression data. One goal in mining gene expression data is to determine how the expression of any particular gene might affect the expression of other genes. To find relationships between different genes, association rules have been applied to gene expression data set [1]. A notable limitation of association rule mining method is that only the association in a single profile experiment can be detected. It cannot be used to find rules across different condition profiles or different time point profile experiments. However, with the appearance of time-series microarray data, it became possible to analyze the temporal relationship between genes. In this paper, we analyze the time-series microarray gene expression data to extract the sequential patterns which are similar to the association rules between genes among different time points in the yeast cell cycle. The sequential patterns found in our work can catch the associations between different genes which express or repress at diverse time points. We have applied sequential pattern mining method to time-series microarray gene expression data and discovered a number of sequential patterns from two groups of genes (test, control) and more sequential patterns have been discovered from test group (same CO term group) than from the control group (different GO term group). This result can be a support for the potential of sequential patterns which is capable of catching the biologically meaningful association between genes.

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Esophageal Rupture Due to Diving in Shallow Waters

  • Han, Sung Ho;Chon, Soon-Ho;Lee, Jong Hyun;Lee, Min Koo;Kwon, Oh Sang;Kim, Kyoung Hwan;Kim, Jung Suk;Lee, Ho hyoung;Chon, June Raphael
    • Journal of Trauma and Injury
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    • v.31 no.1
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    • pp.16-18
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    • 2018
  • Delayed esophageal rupture due to blunt injury is not new. However, rupture due to suspected barotrauma is very rare. We describe a case of esophageal rupture in a male 24-year-old patient after diving in shallow waters. The patient was quadriplegic and could not experience the typical chest pain related to rupture and resulting mediastinitis. The rupture was discovered 4 days after emergency decompressive laminectomy and fusion for his cervical spine. The rupture was evidently caused by barotrauma and was discovered four days after admission. He underwent primary closure and pericardial flap as a life-saving procedure.

Peripheral Lung Cancer Arising in Lung Cancer -A case report- (폐장의 반흔에서 발생하는 반흔암종 1례 보고)

  • Jin, Jae-Gwon;Yu, Se-Yeong
    • Journal of Chest Surgery
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    • v.15 no.2
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    • pp.174-182
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    • 1982
  • On the right lower lobe, scar carcinoma was presented in the Korean male, 56 years old, in February, 1982. His tumor is moderate differentiated adenocarcinoma. Scar carcinoma, a rare form of adenocarcinoma, is usually discovered on autopsy and rarely on surgical resected specimen and these tumors are found in areas of lung scarring. Most of the tumors are adenocarcinoma and found in the upper lobes and related to infarcts, tuberculous scars. No relationship between smoking and scar cancers were reported. The scar cancers are becoming more common. An apparent increase in scar cancer in the periphery of the lung was reported in America. Scar cancer does not present special clinical symptoms and signs, except manifestations of surrounded tissue compressed by large tumors in far advanced stage. These tumors progress slowly and metastasize late but characteristic signs on scar area of the lung can be discovered from the early stage on X-ray examination [solitary peripheral nodule and scar]. So careful study on chest x-ray film was acquired and if necessary, conservative resection of the lesion is indicated because the long term prognosis is not at all bad.

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A Study on the effect of the Scholastic Aptitude Test on flight aptitude (비행적성에 영향을 미치는 대학수학능력시험에 관한 연구)

  • Noh, Yo-Sup
    • Journal of the Korean Society for Aviation and Aeronautics
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    • v.18 no.1
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    • pp.83-88
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    • 2010
  • The study is intended to help to select the pilot candidates with exceptional flight aptitude ability and to investigate the relationship between the results of the scholastic aptitude test and the flight aptitude. It is intended that the research will help to draw recommendations on the relevant fields of the scholastic aptitude test that is to be used to select the high caliber candidates with exceptional flight aptitude ability, to gauge the resulting effectiveness of its application and helping to revise the university's syllabus accordingly. From the study, korean, mathematics, english grade and the flight aptitude test results have all shown to hold mutual relationship and through simple correlation analysis, it was discovered that mathematics and English are the two factors that affect the results of the flight aptitude test, with the extent of its impact graded in descending order of English, mathematics and Korean. Lastly, the logistic regression analysis have discovered that the mathematics grade has significant effect on the classification of the flight aptitude and non aptitude category groups, and English also has significant influence close to the 0.05 p-values. It is believed that should the findings of this study be considered as part of the selection process of the university applicants of the department of aeronautical science, making discovery of candidates of higher quality is expected.

A Study on the region of Wuiwan(胃脘) -Focusing on the related disease- (위완(胃脘)의 부위에 대한 고찰 -관련 병증을 중심으로-)

  • Yun, Ki-ryoung;Baik, You-sang;Jang, Woo-chang;Jeong, Chang-hyun
    • Journal of Korean Medical classics
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    • v.30 no.4
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    • pp.95-108
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    • 2017
  • Objective : The current wuiwan poses a challenge in understanding related disease because one term refers to many different parts. Therefore, the objective of this paper is to review historical documents and define the areas of wuiwan revolving around the wuiwan-related disease. Method : The Sikuquanshu database, Traditional Chinese Medical(TCM) books webdatabase were studied, and selections were made from the texts that discussed wuiwan. Result & Conclusion : The term wuiwan is used to refer to stomach's capacity. The word wuiwan is first discovered in Neijing. wuiwan-related disease as shown in Neijing does not move beyond the scope of stomach. The view of seeing wuiwan as part of esophagus is discovered in the text which explains dysphagia, and it is believed that this expression was used in the purpose of pointing the airway and the esphagus. Therefore, the reason wuiwan was viwed as esophagus has to be confined within the texts in documents that explain dysphagia or within the Four-Constitution Medicine. Generally, it is more reasonable to see wuiwan within the scope of stomach.

IMTAR: Incremental Mining of General Temporal Association Rules

  • Dafa-Alla, Anour F.A.;Shon, Ho-Sun;Saeed, Khalid E.K.;Piao, Minghao;Yun, Un-Il;Cheoi, Kyung-Joo;Ryu, Keun-Ho
    • Journal of Information Processing Systems
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    • v.6 no.2
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    • pp.163-176
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    • 2010
  • Nowadays due to the rapid advances in the field of information systems, transactional databases are being updated regularly and/or periodically. The knowledge discovered from these databases has to be maintained, and an incremental updating technique needs to be developed for maintaining the discovered association rules from these databases. The concept of Temporal Association Rules has been introduced to solve the problem of handling time series by including time expressions into association rules. In this paper we introduce a novel algorithm for Incremental Mining of General Temporal Association Rules (IMTAR) using an extended TFP-tree. The main benefits introduced by our algorithm are that it offers significant advantages in terms of storage and running time and it can handle the problem of mining general temporal association rules in incremental databases by building TFP-trees incrementally. It can be utilized and applied to real life application domains. We demonstrate our algorithm and its advantages in this paper.

A Study on Didactic Transposition Method and Students' Understanding for Graph's Trail (그래프의 경로에 대한 교수학적 변환 방식과 학생들의 이해 분석)

  • Shin, Bo-Mi
    • Journal of the Korean School Mathematics Society
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    • v.13 no.2
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    • pp.289-301
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    • 2010
  • This study discovered that instructional objectives of graphs which are dealt with in Math I of the revised curriculum are not matched with those of Discrete Mathematics in the 7th Curriculum. Based on the findings, this study analysed didactic transposition method of trail in graph and matrix of Math I and students' understanding about trail. Then this study discovered that though the concept definition of trail in Math I of the revised curriculum, some textbooks and students tend to consider it as the path. The concept definition of trail is significant in systems that deal with Euler Circuits(Euler Closed trail) and Hamilton Cycle. Then it is not easy to find the value of trail in Math I of the revised curriculum.

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A Study on Information Security Management of Hospital Web Sites (의료기관 종별 웹 사이트 정보보안 관리 실태 연구)

  • Kim, Jong-Min;Ryu, Hwang-Gun
    • The Korean Journal of Health Service Management
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    • v.9 no.2
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    • pp.23-32
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    • 2015
  • In this paper, we evaluated web security vulnerability and privacy information management of hospital web sites which are registered at the Korea Hospital Association. Vulnerability Scanner (WVS) based on the OWASP Top 10 was used to evaluate the web security vulnerability of the web sites. And to evaluate the privacy information management, we used ten rules which were based on guidelines for protecting privacy information on web sites. From the results of the evaluation, we discovered tertiary hospitals had relatively excellent web security compared to other type of hospitals. But all the hospital types had not only high level vulnerabilities but also the other level of vulnerabilities. Additionally, 97% of the hospital web sites had a certain level of vulnerability, so a security inspection is needed to secure the web sites. We discovered a few SQL Injection and XSS vulnerabilities in the web sites of tertiary hospitals. However, these are very critical vulnerabilities, so all hospital types have to be inspected to protect their web sites against attacks from hacker. On the other hand, the inspection results of the tertiary hospitals for privacy information management had a better compliance rate than that of the other hospital types.

Detection of Variable Stars in the Open Cluster M11 Using Difference Image Analysis Pipeline

  • Lee, Chung-Uk;Koo, Jae-Rim;Kim, Seung-Lee;Lee, Jae-Woo;Park, Byeong-Gon;Han, Cheong-Ho
    • Journal of Astronomy and Space Sciences
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    • v.27 no.4
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    • pp.289-307
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    • 2010
  • We developed a photometric pipeline to be used for a wide field survey. This pipeline employs the difference image analysis (DIA) method appropriate for the photometry of star dense field such as the Galactic bulge. To verify the performance of pipeline, the observed dataset of the open cluster M11 was re-processed. One hundred seventy eight variable stars were newly discovered by analyzing the light curves of which photometric accuracy was improved through the DIA. The total number of variable stars in the M11 observation region is 335, including 157 variable stars discovered by previous studies. We present the catalogue and light curves for the 178 variable stars. This study shows that the photometric pipeline using the DIA is very useful in the detection of variable stars in a cluster.

A Study on the Door Discovered at the Shinchang-dong Wetland Site (광주(光州) 신창동(新昌洞) 저습지출토(低濕地出土) 나무문짝(비문(扉門))에 관한 연구(硏究))

  • Cheon, Deuk-Youm;Shin, Sang-Hyo
    • Journal of architectural history
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    • v.15 no.5
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    • pp.7-18
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    • 2006
  • A lot of relics were unearthed in the Shinchang-dong wetland site, which can help restore prehistoric life style, including construction tools such as wood doors, wood hammers, ax handgrips, sickle handgrips, wedges, awls, wood pillars and connection members, food vessels made of earth or wood and fish, shell fish, seeds and remains of weapons. In particular, a door was found in the site, which was measured at 110cm long and 37cm wide. If restored it will be 75cm wide. The door seems to date back as far as the 1st century B. C., which would be the oldest one ever discovered in Korea. This paper is intended to explore the implications of the door by investigating the environment of the Shinchang-dong wetland site bearing the relics intact, manufacturing techniques and times of manufacturing of the door as well as attributes of doors presented in the literature related to old time architecture such as Goguryeo tomb paintings and house-shaped vessels. It also intends to provide basic data for study of residential architecture in prehistoric times.

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